Click here to switch to the map view.

The map label for this gene is csxA [H]

Identifier: 59713289

GI number: 59713289

Start: 118786

End: 121194

Strand: Reverse

Name: csxA [H]

Synonym: VF_A0106

Alternate gene names: 59713289

Gene position: 121194-118786 (Counterclockwise)

Preceding gene: 59713292

Following gene: 59713284

Centisome position: 9.11

GC content: 39.48

Gene sequence:

>2409_bases
ATGTCGCAAATTTCTCTTAATGGCAAATGGATACTCACCTCTCCAGCGCATTCGCATCTTGCAATTCCAATGACGGTTCC
CGGCGATAATTACCATGCTTTATACCAAGCAGGGATCATTACCAATCCATATATGGGAACGAACGAAAATGAGGTTCAAT
GGGTAAGAGAATGCGATTGGCATCTATCTCAAGAATTTTCTCTTTCACCACAAGAGATGAGTGCTGCATCTTTAATACTC
AATTTAAGTCGTGTTGATACATTGGCTAATGTCTTTATTAATAATGAACTTGTTTTAAGCTCTACTAACCAATTTCAACG
CCACCGCATTGATATCAAACCATTTGTTAAACCGGGTGATAACACGATTTCAGTTCATTTCTCTCGAGTCGATGAAGAGG
CGCTATCAAGAGCGAAGAAATTACCTATGCCTATCCCATGGGCGGTAGGGAATAACCAGCTTCCACACATGAACCTAATA
CGCAAAACACAATGCCACTCTGGTTGGGATTGGGGAATTTGCTTAATGGTTTCTGGTATCTATGATCCAATTTATATTGA
GGTTGTAAAAAAGATTGAATTAAGCTCAATCGAAACTGCACAAATTTGGTATCAAGGTGCTGTTGATCTTACGGTTAATG
TTAAACATGAGTGTATTGCGGGACAAGCGATTACCGTTAATTTCAATGACGAAATTCACACGTTAATTAGCCATGAGAGT
GGTGAAACAAGCACCATTTTCCATATTGAAAATCCTGAACTTTGGTGGCCTTCTGGCTACGGTGAGCAACCTTTATATTC
ACTCACCGTTGAACTGGATGAACAAACAATCACAAAAAGAGTTGGCTTACGTCAATTAGAGCTTAATAACAAAAATGATG
AAATTGGCTCAGCGATGGAATTTGTGATTAATGGTTTTCCTATTAACTCAAAAGGAGCGAATTGGATCCCTATGGATGCA
ATGCCAAGCCTTGAGTCTGAAAGCCGTTACCGAGAATTATTAACCAGTGCTAAAGACGCTAACATGAACATGATCCGTGT
TTGGGGAGGTGGTCAATATGAGTCCGAACTATTCTACGATCTCTGTGATGAACTGGGATTAATGGTATGGCAAGACATGA
TGTTTGCTTGCTCCCTTTATCCTTCTACGGATGCATTTTTAAAAGACGTTGAACCTGAGATCCGACAACAAATTCAGCGC
TTAAAAGATCATCCCTCAATTGTTCTTTGGTGTGGCGATAACGAAGTTATTGGAGCGATTGGTTGGTACGATGAATCTAA
GAACAATAAAACAACCTATACGGTTAATTACGATCGCTTAAATCGCAATATTGCTCAATGGATTGCAGAAGAAGATCCAA
GTCGTCGATTCTGGACTAGCTCTCCTTGTAATGGCGATATGGATTTTGGTGATGCTTGGCATAATGATAACCGCGGTGAT
ATGCACTTTTGGGATGTTTGGCACTCAGGAAAATCATTTGATGCTTATCAAGATATCAAACCACGCTTTTGCTCTGAGTT
TGGTTTTCAGTCTTGGCCTTCTTTTTCAGAGGTAAAAACCTTTGTTCCTGAAGAAGACTGGAATGTCACGTCTCCGACCT
TTGAAGGACACCAAAAAAATGGACGTGGTAATAGCATCATCACTGAGATGTTTACTCGTTACTTCCGCTTTCCATCTAAC
TTTGAACAAATGCTATATTTAAGCCAAGTACAACAAGCCATTGCGATTAAAACTGGTTGCGAATATTGGCGTGCAATCAG
TCCTATATGTCGAGGCATGCTCTATTGGCAACTCAATGATAATTGGCCTGTGAGTTCATGGTCGAGTATTGAATACAGCG
GTCGTTGGAAGCAGCTTCATTATCATGCGAAACGCTTCTTCGCGCCAACTTACGTGCCTTTTGAAGAAACAAATTCTGAA
TTACGCATTCGAGCGGTCAATGATCATCGAACCGAAGCTCATATTGATGGCACTGTTTATTGGATGGATTTTAATGGGGA
ACTACTGGGTAAATGGGCTGTAAATTACACCATTGAGGAAGATGGCAATGATGTTATTTGGTCATTAAGTAAAGAAAAAT
TCCAAGTTAGTGAGAATAATAGCTTTTTCTTTATTGAAATCGAAGTTAACGGAGAGTCTATTCAAAACACGTGGTTTGCA
ACCCCTAAACTCAAACAGCTAACAATGAAGAAGGCTAAAATCAATCTTATTCAATCAGGAACGATGCTTACCCTTCAATC
AGATAATCCTGCTTTCTTTGTTCACTTAGAACATGACGGTAAAGGACAATTTAGTGACTCGAGTTTTACATTATTACCTG
AAAAACCGGTAACCATTGAGTATCTTGGTGATGATATCGAAACTCTAAAAAATACACTCCGAGTGTATGATTTATCCAAT
AGCTACTGA

Upstream 100 bases:

>100_bases
GATTCACTCTCATCCGAGAATAGAGTCACATATTTTCTCTGCTTTCAGACATACACTTCTTGCAATTTCTTCACTATATA
CGGCATCAGAAGGATTTTTT

Downstream 100 bases:

>100_bases
GAAAACTCACCACTCTAATAAAAAAGCCAATGATCATTTCATTGGCTTTTTCATTGAGCTATGAGGTTATTTGACCAAAT
ATTCCTTGGACACTTTATCA

Product: beta-mannosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 802; Mature: 801

Protein sequence:

>802_residues
MSQISLNGKWILTSPAHSHLAIPMTVPGDNYHALYQAGIITNPYMGTNENEVQWVRECDWHLSQEFSLSPQEMSAASLIL
NLSRVDTLANVFINNELVLSSTNQFQRHRIDIKPFVKPGDNTISVHFSRVDEEALSRAKKLPMPIPWAVGNNQLPHMNLI
RKTQCHSGWDWGICLMVSGIYDPIYIEVVKKIELSSIETAQIWYQGAVDLTVNVKHECIAGQAITVNFNDEIHTLISHES
GETSTIFHIENPELWWPSGYGEQPLYSLTVELDEQTITKRVGLRQLELNNKNDEIGSAMEFVINGFPINSKGANWIPMDA
MPSLESESRYRELLTSAKDANMNMIRVWGGGQYESELFYDLCDELGLMVWQDMMFACSLYPSTDAFLKDVEPEIRQQIQR
LKDHPSIVLWCGDNEVIGAIGWYDESKNNKTTYTVNYDRLNRNIAQWIAEEDPSRRFWTSSPCNGDMDFGDAWHNDNRGD
MHFWDVWHSGKSFDAYQDIKPRFCSEFGFQSWPSFSEVKTFVPEEDWNVTSPTFEGHQKNGRGNSIITEMFTRYFRFPSN
FEQMLYLSQVQQAIAIKTGCEYWRAISPICRGMLYWQLNDNWPVSSWSSIEYSGRWKQLHYHAKRFFAPTYVPFEETNSE
LRIRAVNDHRTEAHIDGTVYWMDFNGELLGKWAVNYTIEEDGNDVIWSLSKEKFQVSENNSFFFIEIEVNGESIQNTWFA
TPKLKQLTMKKAKINLIQSGTMLTLQSDNPAFFVHLEHDGKGQFSDSSFTLLPEKPVTIEYLGDDIETLKNTLRVYDLSN
SY

Sequences:

>Translated_802_residues
MSQISLNGKWILTSPAHSHLAIPMTVPGDNYHALYQAGIITNPYMGTNENEVQWVRECDWHLSQEFSLSPQEMSAASLIL
NLSRVDTLANVFINNELVLSSTNQFQRHRIDIKPFVKPGDNTISVHFSRVDEEALSRAKKLPMPIPWAVGNNQLPHMNLI
RKTQCHSGWDWGICLMVSGIYDPIYIEVVKKIELSSIETAQIWYQGAVDLTVNVKHECIAGQAITVNFNDEIHTLISHES
GETSTIFHIENPELWWPSGYGEQPLYSLTVELDEQTITKRVGLRQLELNNKNDEIGSAMEFVINGFPINSKGANWIPMDA
MPSLESESRYRELLTSAKDANMNMIRVWGGGQYESELFYDLCDELGLMVWQDMMFACSLYPSTDAFLKDVEPEIRQQIQR
LKDHPSIVLWCGDNEVIGAIGWYDESKNNKTTYTVNYDRLNRNIAQWIAEEDPSRRFWTSSPCNGDMDFGDAWHNDNRGD
MHFWDVWHSGKSFDAYQDIKPRFCSEFGFQSWPSFSEVKTFVPEEDWNVTSPTFEGHQKNGRGNSIITEMFTRYFRFPSN
FEQMLYLSQVQQAIAIKTGCEYWRAISPICRGMLYWQLNDNWPVSSWSSIEYSGRWKQLHYHAKRFFAPTYVPFEETNSE
LRIRAVNDHRTEAHIDGTVYWMDFNGELLGKWAVNYTIEEDGNDVIWSLSKEKFQVSENNSFFFIEIEVNGESIQNTWFA
TPKLKQLTMKKAKINLIQSGTMLTLQSDNPAFFVHLEHDGKGQFSDSSFTLLPEKPVTIEYLGDDIETLKNTLRVYDLSN
SY
>Mature_801_residues
SQISLNGKWILTSPAHSHLAIPMTVPGDNYHALYQAGIITNPYMGTNENEVQWVRECDWHLSQEFSLSPQEMSAASLILN
LSRVDTLANVFINNELVLSSTNQFQRHRIDIKPFVKPGDNTISVHFSRVDEEALSRAKKLPMPIPWAVGNNQLPHMNLIR
KTQCHSGWDWGICLMVSGIYDPIYIEVVKKIELSSIETAQIWYQGAVDLTVNVKHECIAGQAITVNFNDEIHTLISHESG
ETSTIFHIENPELWWPSGYGEQPLYSLTVELDEQTITKRVGLRQLELNNKNDEIGSAMEFVINGFPINSKGANWIPMDAM
PSLESESRYRELLTSAKDANMNMIRVWGGGQYESELFYDLCDELGLMVWQDMMFACSLYPSTDAFLKDVEPEIRQQIQRL
KDHPSIVLWCGDNEVIGAIGWYDESKNNKTTYTVNYDRLNRNIAQWIAEEDPSRRFWTSSPCNGDMDFGDAWHNDNRGDM
HFWDVWHSGKSFDAYQDIKPRFCSEFGFQSWPSFSEVKTFVPEEDWNVTSPTFEGHQKNGRGNSIITEMFTRYFRFPSNF
EQMLYLSQVQQAIAIKTGCEYWRAISPICRGMLYWQLNDNWPVSSWSSIEYSGRWKQLHYHAKRFFAPTYVPFEETNSEL
RIRAVNDHRTEAHIDGTVYWMDFNGELLGKWAVNYTIEEDGNDVIWSLSKEKFQVSENNSFFFIEIEVNGESIQNTWFAT
PKLKQLTMKKAKINLIQSGTMLTLQSDNPAFFVHLEHDGKGQFSDSSFTLLPEKPVTIEYLGDDIETLKNTLRVYDLSNS
Y

Specific function: Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration. Has no beta-mannosidase activity [H]

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Secreted, extracellular space [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI84798622, Length=850, Percent_Identity=33.4117647058824, Blast_Score=369, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17550784, Length=718, Percent_Identity=29.6657381615599, Blast_Score=309, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24643838, Length=882, Percent_Identity=28.7981859410431, Blast_Score=288, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24643840, Length=787, Percent_Identity=29.987293519695, Blast_Score=275, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.165 [H]

Molecular weight: Translated: 92527; Mature: 92396

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQISLNGKWILTSPAHSHLAIPMTVPGDNYHALYQAGIITNPYMGTNENEVQWVRECDW
CCEEEECCEEEEECCCCCCEEEEEEECCCCEEEEEEECCEECCCCCCCCCHHHHHHHCCC
HLSQEFSLSPQEMSAASLILNLSRVDTLANVFINNELVLSSTNQFQRHRIDIKPFVKPGD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHCCCCCCCCCCCC
NTISVHFSRVDEEALSRAKKLPMPIPWAVGNNQLPHMNLIRKTQCHSGWDWGICLMVSGI
CEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCC
YDPIYIEVVKKIELSSIETAQIWYQGAVDLTVNVKHECIAGQAITVNFNDEIHTLISHES
CCHHHHHHHHHHHCCCCEEEEEEEECEEEEEEEECEEEECCCEEEEEECCCEEEEEECCC
GETSTIFHIENPELWWPSGYGEQPLYSLTVELDEQTITKRVGLRQLELNNKNDEIGSAME
CCCEEEEEECCCCEECCCCCCCCCEEEEEEEECHHHHHHHCCCEEEECCCCCCHHHHHHH
FVINGFPINSKGANWIPMDAMPSLESESRYRELLTSAKDANMNMIRVWGGGQYESELFYD
HHEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHH
LCDELGLMVWQDMMFACSLYPSTDAFLKDVEPEIRQQIQRLKDHPSIVLWCGDNEVIGAI
HHHHHHHHHHHHHHHHEECCCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEE
GWYDESKNNKTTYTVNYDRLNRNIAQWIAEEDPSRRFWTSSPCNGDMDFGDAWHNDNRGD
EEEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCC
MHFWDVWHSGKSFDAYQDIKPRFCSEFGFQSWPSFSEVKTFVPEEDWNVTSPTFEGHQKN
EEEEEEECCCCCCCHHHHCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GRGNSIITEMFTRYFRFPSNFEQMLYLSQVQQAIAIKTGCEYWRAISPICRGMLYWQLND
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC
NWPVSSWSSIEYSGRWKQLHYHAKRFFAPTYVPFEETNSELRIRAVNDHRTEAHIDGTVY
CCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEEECEEEE
WMDFNGELLGKWAVNYTIEEDGNDVIWSLSKEKFQVSENNSFFFIEIEVNGESIQNTWFA
EEECCCCEEEEEEEEEEEECCCCEEEEEECCCEEEEECCCCEEEEEEEECCCCCCCEEEC
TPKLKQLTMKKAKINLIQSGTMLTLQSDNPAFFVHLEHDGKGQFSDSSFTLLPEKPVTIE
CCCHHHHHHHHHEEEEEECCEEEEEECCCCEEEEEEEECCCCCCCCCCEEEECCCCEEEE
YLGDDIETLKNTLRVYDLSNSY
ECCCHHHHHHHCEEEEECCCCC
>Mature Secondary Structure 
SQISLNGKWILTSPAHSHLAIPMTVPGDNYHALYQAGIITNPYMGTNENEVQWVRECDW
CEEEECCEEEEECCCCCCEEEEEEECCCCEEEEEEECCEECCCCCCCCCHHHHHHHCCC
HLSQEFSLSPQEMSAASLILNLSRVDTLANVFINNELVLSSTNQFQRHRIDIKPFVKPGD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHCCCCCCCCCCCC
NTISVHFSRVDEEALSRAKKLPMPIPWAVGNNQLPHMNLIRKTQCHSGWDWGICLMVSGI
CEEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCC
YDPIYIEVVKKIELSSIETAQIWYQGAVDLTVNVKHECIAGQAITVNFNDEIHTLISHES
CCHHHHHHHHHHHCCCCEEEEEEEECEEEEEEEECEEEECCCEEEEEECCCEEEEEECCC
GETSTIFHIENPELWWPSGYGEQPLYSLTVELDEQTITKRVGLRQLELNNKNDEIGSAME
CCCEEEEEECCCCEECCCCCCCCCEEEEEEEECHHHHHHHCCCEEEECCCCCCHHHHHHH
FVINGFPINSKGANWIPMDAMPSLESESRYRELLTSAKDANMNMIRVWGGGQYESELFYD
HHEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHH
LCDELGLMVWQDMMFACSLYPSTDAFLKDVEPEIRQQIQRLKDHPSIVLWCGDNEVIGAI
HHHHHHHHHHHHHHHHEECCCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEE
GWYDESKNNKTTYTVNYDRLNRNIAQWIAEEDPSRRFWTSSPCNGDMDFGDAWHNDNRGD
EEEECCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCC
MHFWDVWHSGKSFDAYQDIKPRFCSEFGFQSWPSFSEVKTFVPEEDWNVTSPTFEGHQKN
EEEEEEECCCCCCCHHHHCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GRGNSIITEMFTRYFRFPSNFEQMLYLSQVQQAIAIKTGCEYWRAISPICRGMLYWQLND
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECC
NWPVSSWSSIEYSGRWKQLHYHAKRFFAPTYVPFEETNSELRIRAVNDHRTEAHIDGTVY
CCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEEECEEEE
WMDFNGELLGKWAVNYTIEEDGNDVIWSLSKEKFQVSENNSFFFIEIEVNGESIQNTWFA
EEECCCCEEEEEEEEEEEECCCCEEEEEECCCEEEEECCCCEEEEEEEECCCCCCCEEEC
TPKLKQLTMKKAKINLIQSGTMLTLQSDNPAFFVHLEHDGKGQFSDSSFTLLPEKPVTIE
CCCHHHHHHHHHEEEEEECCEEEEEECCCCEEEEEEEECCCCCCCCCCEEEECCCCEEEE
YLGDDIETLKNTLRVYDLSNSY
ECCCHHHHHHHCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]