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The map label for this gene is aer [H]

Identifier: 59713275

GI number: 59713275

Start: 102112

End: 103668

Strand: Reverse

Name: aer [H]

Synonym: VF_A0092

Alternate gene names: 59713275

Gene position: 103668-102112 (Counterclockwise)

Preceding gene: 59713277

Following gene: 59713274

Centisome position: 7.79

GC content: 37.57

Gene sequence:

>1557_bases
ATGAAGACAGATGCGTCTAACAATAAAGAAGTTCTATTTCCCAAAGAATATAACTTGTTATCAATCACCTCCCCATCAAG
TCATATTACCTACGCAAGTAACAATTTTTGTGAAGTAGCTGGATTTACGTTAGATGAACTGAATTCACAACCCCATAATA
TCGTTCGCCATCCAGATATGCCGAGTGAAGCATTTAAAGATATGTGGTCTCACCTAAAAAACAAAAAATCATGGATGGGA
TTAGTTAAAAATAAATGTAAAGACGGAAATTACTATTGGGTTGACGCCTTCGCATCTCCTATCCTTCAAAATGGTGAAAT
AAAAGAGTATCAATCTGTTAGATTAAGCCCTTCTCGAGAGCATATTGCTAACGCTGAAAAAGTATATGCATCATTAAAAT
CAGGTAAGAAACCATTAAAACTAACATTGCCAAGAACTCGTTTATGGCAACGCTTTGCTTTAACATTAATACCTAGTTTT
ATTGTCGCGGCTCTGATTTCATATCAATGGTCCCCTTTATTTGGTTTAAGCCTCTTGAGTACACTTTCGCTATTGAGTGT
CTATTCATTAACTCGTCGTTTAGAGCAATTATCAACTAAAGCAAAAGCGGTCTTTGATAATCCACTAATGGAATTAATTT
ACACGAATCATGTGGATGATATTTCAGAAATAGAACTTGCGTTAAAAATGCGTCAATCTGAAATTAATGCCATTATTGGA
CGCATTCAAGACTCTAACGAGCAGATTGAAACACTAGCGAAATCATCAACTTCTAACTGCCTAGATACCGTTAATAACCT
AAACGAACAAACTCAAGAAACTCATCAGGTTGCTAATGCTATCCAAGAAATGTCAGCTTCCGTTAACGATATTGCGGCAA
ATGTTCTAAGTACAGCTCAAGCAACAGAAGAAGCATATCAAGTCACTTCTGAGGGAATGGCAACAGTCACAGAGACCGTA
AACTCAATCCAAATGCTTTCTACACAATTAACCAATGCCTCCAATATTATTGCAACACTGGAAGCTCGCGGTAACGAAAT
TGGTTCTGTGTTAACCGTGATACAAGCGATTGCAGAACAAACAAATCTATTAGCATTAAATGCGGCAATCGAAGCTGCAC
GAGCCGGAGAACAAGGCAGAGGATTTGCCGTTGTTGCTGATGAAGTCAGAGCATTAGCTCAGCGAAGTCAAGATTCAGCA
AAAGAAATTCAAGATATGATCAAACAGATACAACAAAGTACACAAGATGCCGTTGAAGCAATGGAACAAGGTAAATCACT
ATCTGGTGTATGCGTAGATTCAGCAAATAAATCAGGCCATACGTTACAAGAATCCTTTGAGCAAGTGAGTGCAATTGCTG
AAAAAAACACTCAAATATCCGTTGCGATTGAGCAAATTGTCAAAGTATCCGAAGACATGAATACAAACATTCAGTCAATT
AATAATGTCTGTGAGCATACACACAACATTGCAAATGAAACGATGAAAGAGTGCAGTATTCTCTCAGAAACAATTGATTC
TCAAGGAGCTCTGGTCGCTCAATTCCGAAACGTATAA

Upstream 100 bases:

>100_bases
CAAGAAAAAATAGGCACAAAACCTCAATAAAAATACAGTATGGTGTAATATTTGCTTACATTTAGCTGCTGAATTTATCG
AGACAAAAAGAGACAAACAC

Downstream 100 bases:

>100_bases
ACAGCCACCCGATGTTATCATCTTAGGGCTTTCGTCTTTAAATCTGCGTCTTTTTAACTACAAATTGAGCTTTTTATTTA
TCCGACTTTCTCCTTACTTA

Product: methyl-accepting chemotaxis protein, putative aerotaxis receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MKTDASNNKEVLFPKEYNLLSITSPSSHITYASNNFCEVAGFTLDELNSQPHNIVRHPDMPSEAFKDMWSHLKNKKSWMG
LVKNKCKDGNYYWVDAFASPILQNGEIKEYQSVRLSPSREHIANAEKVYASLKSGKKPLKLTLPRTRLWQRFALTLIPSF
IVAALISYQWSPLFGLSLLSTLSLLSVYSLTRRLEQLSTKAKAVFDNPLMELIYTNHVDDISEIELALKMRQSEINAIIG
RIQDSNEQIETLAKSSTSNCLDTVNNLNEQTQETHQVANAIQEMSASVNDIAANVLSTAQATEEAYQVTSEGMATVTETV
NSIQMLSTQLTNASNIIATLEARGNEIGSVLTVIQAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRSQDSA
KEIQDMIKQIQQSTQDAVEAMEQGKSLSGVCVDSANKSGHTLQESFEQVSAIAEKNTQISVAIEQIVKVSEDMNTNIQSI
NNVCEHTHNIANETMKECSILSETIDSQGALVAQFRNV

Sequences:

>Translated_518_residues
MKTDASNNKEVLFPKEYNLLSITSPSSHITYASNNFCEVAGFTLDELNSQPHNIVRHPDMPSEAFKDMWSHLKNKKSWMG
LVKNKCKDGNYYWVDAFASPILQNGEIKEYQSVRLSPSREHIANAEKVYASLKSGKKPLKLTLPRTRLWQRFALTLIPSF
IVAALISYQWSPLFGLSLLSTLSLLSVYSLTRRLEQLSTKAKAVFDNPLMELIYTNHVDDISEIELALKMRQSEINAIIG
RIQDSNEQIETLAKSSTSNCLDTVNNLNEQTQETHQVANAIQEMSASVNDIAANVLSTAQATEEAYQVTSEGMATVTETV
NSIQMLSTQLTNASNIIATLEARGNEIGSVLTVIQAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRSQDSA
KEIQDMIKQIQQSTQDAVEAMEQGKSLSGVCVDSANKSGHTLQESFEQVSAIAEKNTQISVAIEQIVKVSEDMNTNIQSI
NNVCEHTHNIANETMKECSILSETIDSQGALVAQFRNV
>Mature_518_residues
MKTDASNNKEVLFPKEYNLLSITSPSSHITYASNNFCEVAGFTLDELNSQPHNIVRHPDMPSEAFKDMWSHLKNKKSWMG
LVKNKCKDGNYYWVDAFASPILQNGEIKEYQSVRLSPSREHIANAEKVYASLKSGKKPLKLTLPRTRLWQRFALTLIPSF
IVAALISYQWSPLFGLSLLSTLSLLSVYSLTRRLEQLSTKAKAVFDNPLMELIYTNHVDDISEIELALKMRQSEINAIIG
RIQDSNEQIETLAKSSTSNCLDTVNNLNEQTQETHQVANAIQEMSASVNDIAANVLSTAQATEEAYQVTSEGMATVTETV
NSIQMLSTQLTNASNIIATLEARGNEIGSVLTVIQAIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRSQDSA
KEIQDMIKQIQQSTQDAVEAMEQGKSLSGVCVDSANKSGHTLQESFEQVSAIAEKNTQISVAIEQIVKVSEDMNTNIQSI
NNVCEHTHNIANETMKECSILSETIDSQGALVAQFRNV

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=478, Percent_Identity=33.4728033472803, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI1787690, Length=337, Percent_Identity=30.5637982195846, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI2367378, Length=295, Percent_Identity=27.7966101694915, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788194, Length=209, Percent_Identity=31.1004784688995, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788195, Length=209, Percent_Identity=34.4497607655502, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57094; Mature: 57094

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDASNNKEVLFPKEYNLLSITSPSSHITYASNNFCEVAGFTLDELNSQPHNIVRHPDM
CCCCCCCCCCEECCCCCCEEEECCCCCCEEECCCCCHHHCCCCHHHCCCCCCCCCCCCCC
PSEAFKDMWSHLKNKKSWMGLVKNKCKDGNYYWVDAFASPILQNGEIKEYQSVRLSPSRE
CHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCHHHHHCCCCCCHH
HIANAEKVYASLKSGKKPLKLTLPRTRLWQRFALTLIPSFIVAALISYQWSPLFGLSLLS
HHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TLSLLSVYSLTRRLEQLSTKAKAVFDNPLMELIYTNHVDDISEIELALKMRQSEINAIIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RIQDSNEQIETLAKSSTSNCLDTVNNLNEQTQETHQVANAIQEMSASVNDIAANVLSTAQ
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATEEAYQVTSEGMATVTETVNSIQMLSTQLTNASNIIATLEARGNEIGSVLTVIQAIAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEHHHCCCHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRSQDSAKEIQDMIKQIQQSTQDAVEA
HCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MEQGKSLSGVCVDSANKSGHTLQESFEQVSAIAEKNTQISVAIEQIVKVSEDMNTNIQSI
HHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHH
NNVCEHTHNIANETMKECSILSETIDSQGALVAQFRNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure
MKTDASNNKEVLFPKEYNLLSITSPSSHITYASNNFCEVAGFTLDELNSQPHNIVRHPDM
CCCCCCCCCCEECCCCCCEEEECCCCCCEEECCCCCHHHCCCCHHHCCCCCCCCCCCCCC
PSEAFKDMWSHLKNKKSWMGLVKNKCKDGNYYWVDAFASPILQNGEIKEYQSVRLSPSRE
CHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCHHHHHCCCCCCHH
HIANAEKVYASLKSGKKPLKLTLPRTRLWQRFALTLIPSFIVAALISYQWSPLFGLSLLS
HHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TLSLLSVYSLTRRLEQLSTKAKAVFDNPLMELIYTNHVDDISEIELALKMRQSEINAIIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RIQDSNEQIETLAKSSTSNCLDTVNNLNEQTQETHQVANAIQEMSASVNDIAANVLSTAQ
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATEEAYQVTSEGMATVTETVNSIQMLSTQLTNASNIIATLEARGNEIGSVLTVIQAIAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEHHHCCCHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGEQGRGFAVVADEVRALAQRSQDSAKEIQDMIKQIQQSTQDAVEA
HCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MEQGKSLSGVCVDSANKSGHTLQESFEQVSAIAEKNTQISVAIEQIVKVSEDMNTNIQSI
HHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHH
NNVCEHTHNIANETMKECSILSETIDSQGALVAQFRNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]