Click here to switch to the map view.

The map label for this gene is dtpB [H]

Identifier: 59713256

GI number: 59713256

Start: 76715

End: 78190

Strand: Reverse

Name: dtpB [H]

Synonym: VF_A0073

Alternate gene names: 59713256

Gene position: 78190-76715 (Counterclockwise)

Preceding gene: 59713257

Following gene: 59713253

Centisome position: 5.88

GC content: 39.43

Gene sequence:

>1476_bases
ATGTGGAACAAACTAAATAAGTCCATGATGTTTTGCCAAATGATGTTTGGCTTATCATTTTATGGCGTAATGGTTATTTT
AACTCGCTTTTTCCTTGAAGAACTAAACTACAGCGAAGCTGACACCATGATGGTTGTTGGTGCATTTTCATCAATTGGTC
CATTATTTGCCATTGCTGGTGGATTCATTGCTGATAAGTTTTTAGGCGCTTACCGCTCACTAACCATTAGTTACTTTGGT
TTTGCTACTGGTTATGCACTGCTGGTGCTTGGTTCATATACTACAAATGTTCCAATGGCGTTGTGTGGTATTGCATTAGC
GAGCTACGGCCGAGGCTTAATGTCTCCTTCTTACCCAAGCCTATACAAACGTACTTTTGATACTCAAGAGCATTTTGAAA
ACTGCTACCCAGTGAACTATTCAGTCAATAACGTTGGTGCCCTACTAGGCCAATATCTATTCCCGATGTTTGTTCTTGTT
TTAGGGTTCCACGGAAGTTTCTTATTATCATGTGTTCTTGCTTTATTAGCTTTTGCGACTCTGGTGATCTTCCGTAAACC
ACTATTAACCGTTGGTGCTCATATTGATCAAAAACCTGTAAGTATGCAAAACTGGATTTCATTTCTAATCACATCAGTAG
CAATGATTGCCTTAGTTTTCTTCATGTTCTCAAACATGGATATTGGTCAAAACATTGTTTACGGCATTGGCCTTGCAGCT
ATCGGTTACTTCGTGATTTTAATGCTTAAGTCAAAGAAATCGGATGCGCTTAAAATGGGCACGATCCTAATCATGACAGC
ACTAACGACTGCATTCTTTGTCTACTACGGTCAAATGATGACATCAATGACCATGGTAACGATCAATACTATGCGTGGTG
ACCTATTCGACCTTATTCCTATCGCACCTGAAGCATCAATGGCAATGAATCCGCTGTGGTGTATCGTTGCAGGTCCAGTT
ATTGCTATGATTTTCTCAGCACTTGAAAAACGCGATATTCATTTTTCAACAGCAACAAAAATCGGCTTTGCATTCATCTT
AACTGCGATCGCTTTTGGTATTTTAACCATGGCGGTAATGGGTGTGGGTGAAGATGCAATCATTCGTCCTGAAGTATTCT
TACTTATTCACTTCTTCCAAGCATTTGCTGAAGTAATTGTAGGTAGCTTAGTGGTAGCCTTCATTCTGTCTGTTGCACCA
AAACATATAGAAGGCTTCTCTGTAAGTTTATTCTCTGTAGCGATGGCATTAAGTGGCATTATTGGTGCAGTATTCTCAAC
ATCTATTGCGCAAGAAAAAGGTCATGTCATTACTCAAGAGTTTGTACAAACAGTATATGGTAGTTATTTCCAACTACTCA
CTGTACTTGCAGTAGTAATGGTTGCCATCGCTTTCATTGCTTCATTCATCATTCGTAAGATGCTTGAAAGCAGCAAACAA
GCTGAAGAAGTCGAGTTGAAAGAGCAAAAAGCATAA

Upstream 100 bases:

>100_bases
TACTTACAATATTTAAACGATGCTTTTTTGAGAATATCGTACTTTGTTACATTCTTTTGATGATAAAATACGAAAAGTAA
TTATCTAAAAGAGACTCCTT

Downstream 100 bases:

>100_bases
CGCTTGATCTTAATATTCCAATATACATTCTTATAATTCAAAGCCTCGCAATATTGTGAGGCTTTTTATACATACTTAGA
ACCCCAAAGCTTTAACATTG

Product: di-/tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MWNKLNKSMMFCQMMFGLSFYGVMVILTRFFLEELNYSEADTMMVVGAFSSIGPLFAIAGGFIADKFLGAYRSLTISYFG
FATGYALLVLGSYTTNVPMALCGIALASYGRGLMSPSYPSLYKRTFDTQEHFENCYPVNYSVNNVGALLGQYLFPMFVLV
LGFHGSFLLSCVLALLAFATLVIFRKPLLTVGAHIDQKPVSMQNWISFLITSVAMIALVFFMFSNMDIGQNIVYGIGLAA
IGYFVILMLKSKKSDALKMGTILIMTALTTAFFVYYGQMMTSMTMVTINTMRGDLFDLIPIAPEASMAMNPLWCIVAGPV
IAMIFSALEKRDIHFSTATKIGFAFILTAIAFGILTMAVMGVGEDAIIRPEVFLLIHFFQAFAEVIVGSLVVAFILSVAP
KHIEGFSVSLFSVAMALSGIIGAVFSTSIAQEKGHVITQEFVQTVYGSYFQLLTVLAVVMVAIAFIASFIIRKMLESSKQ
AEEVELKEQKA

Sequences:

>Translated_491_residues
MWNKLNKSMMFCQMMFGLSFYGVMVILTRFFLEELNYSEADTMMVVGAFSSIGPLFAIAGGFIADKFLGAYRSLTISYFG
FATGYALLVLGSYTTNVPMALCGIALASYGRGLMSPSYPSLYKRTFDTQEHFENCYPVNYSVNNVGALLGQYLFPMFVLV
LGFHGSFLLSCVLALLAFATLVIFRKPLLTVGAHIDQKPVSMQNWISFLITSVAMIALVFFMFSNMDIGQNIVYGIGLAA
IGYFVILMLKSKKSDALKMGTILIMTALTTAFFVYYGQMMTSMTMVTINTMRGDLFDLIPIAPEASMAMNPLWCIVAGPV
IAMIFSALEKRDIHFSTATKIGFAFILTAIAFGILTMAVMGVGEDAIIRPEVFLLIHFFQAFAEVIVGSLVVAFILSVAP
KHIEGFSVSLFSVAMALSGIIGAVFSTSIAQEKGHVITQEFVQTVYGSYFQLLTVLAVVMVAIAFIASFIIRKMLESSKQ
AEEVELKEQKA
>Mature_491_residues
MWNKLNKSMMFCQMMFGLSFYGVMVILTRFFLEELNYSEADTMMVVGAFSSIGPLFAIAGGFIADKFLGAYRSLTISYFG
FATGYALLVLGSYTTNVPMALCGIALASYGRGLMSPSYPSLYKRTFDTQEHFENCYPVNYSVNNVGALLGQYLFPMFVLV
LGFHGSFLLSCVLALLAFATLVIFRKPLLTVGAHIDQKPVSMQNWISFLITSVAMIALVFFMFSNMDIGQNIVYGIGLAA
IGYFVILMLKSKKSDALKMGTILIMTALTTAFFVYYGQMMTSMTMVTINTMRGDLFDLIPIAPEASMAMNPLWCIVAGPV
IAMIFSALEKRDIHFSTATKIGFAFILTAIAFGILTMAVMGVGEDAIIRPEVFLLIHFFQAFAEVIVGSLVVAFILSVAP
KHIEGFSVSLFSVAMALSGIIGAVFSTSIAQEKGHVITQEFVQTVYGSYFQLLTVLAVVMVAIAFIASFIIRKMLESSKQ
AEEVELKEQKA

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789911, Length=421, Percent_Identity=22.0902612826603, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1787922, Length=461, Percent_Identity=22.7765726681128, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53873; Mature: 53873

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA