Click here to switch to the map view.

The map label for this gene is 59713121

Identifier: 59713121

GI number: 59713121

Start: 2818736

End: 2819452

Strand: Direct

Name: 59713121

Synonym: VF_2514

Alternate gene names: NA

Gene position: 2818736-2819452 (Clockwise)

Preceding gene: 59713120

Following gene: 59713127

Centisome position: 97.28

GC content: 40.86

Gene sequence:

>717_bases
ATGATCCCACATGCTCCTCAAGAAATTTTAAACTGGCCCTCCTTTTTCAAACATAAGCAGGAGATCAGTAAAGATAAACG
GCTAAAAAACTTCTACAAGACAGGAACGTACGAAGAAGAAACACCACTAAGTGACATTGAGTTTGTGGCGCTTGATTTTG
AAACTACGGGATTAGATGCGAACCAAAATAGTATTATCAGTATTGGTTTAGTGCCTTTTACGTTAGAACGTATTTTTTGC
CGTCAATCACAACACTGGTTTGTGAAGGCACAAGACAGCTTAGAAGAAAATTCAGTGGTCATTCATGGTATTACTCACTC
AGACCTACAAGGTGCTCCAGATTTACGCCGGATTTTAGAACAGGTATTAGATGCACTCGCAGGAAAAGTCGTAGTTGTGC
ACTATCGCCGTATAGAACGAGACTTCTTTGATGCAAATCTTCGCAGTTTGATTGGTGAAGGGATCGTTTTCCCAGTCGTA
GATACCATGCAAATTGAAGGAGATTATCAACAAGAACAAGCGAAAGGCTTTATCAATTGGCTTAAAGGTAAGCGTCCAGA
ATCAATTAGACTAGCCAACACTCGGTTGCGTTATGGATTGCCTTCATATCCTCCCCATCACGCATTAACAGATGCAATAG
CGACGGCTGAATTATTTCAAGCACAAGTGAGATACCACTTCTCACCTCACGATCCAATTCGTAAGTTGTGGTTATAA

Upstream 100 bases:

>100_bases
CTTTGAACGCCGTAATTTAAAGGATGCATTCCAAGTATTAAGTAACGCTCAAAATTTCTTAAAATATCGCTATAACGCGA
ATAAATTCTAGGAGCTAATG

Downstream 100 bases:

>100_bases
CGTTTTATTTATATTGCGATGAAATATAAAAAAGCCGATGAAGATAAAACTTCGTCGGCTTTTATGTGCACGTAATAATC
TAAAATAAATTAACTACGGT

Product: DNA polymerase III subunit epsilon

Products: diphosphate; DNAn+1

Alternate protein names: Exonuclease RNAse T And DNA Polymerase III; DNA Polymerase III Epsilon Subunit; Exonuclease; DNA Polymerase III; DNA Polymerase III PolC-Type; Exonuclease Superfamily; DNA Polymerase; DNA Polymerase Exonuclease Activity; Exonuclase; DNA Polymerase III Epsilon-Subunit Paralog

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MIPHAPQEILNWPSFFKHKQEISKDKRLKNFYKTGTYEEETPLSDIEFVALDFETTGLDANQNSIISIGLVPFTLERIFC
RQSQHWFVKAQDSLEENSVVIHGITHSDLQGAPDLRRILEQVLDALAGKVVVVHYRRIERDFFDANLRSLIGEGIVFPVV
DTMQIEGDYQQEQAKGFINWLKGKRPESIRLANTRLRYGLPSYPPHHALTDAIATAELFQAQVRYHFSPHDPIRKLWL

Sequences:

>Translated_238_residues
MIPHAPQEILNWPSFFKHKQEISKDKRLKNFYKTGTYEEETPLSDIEFVALDFETTGLDANQNSIISIGLVPFTLERIFC
RQSQHWFVKAQDSLEENSVVIHGITHSDLQGAPDLRRILEQVLDALAGKVVVVHYRRIERDFFDANLRSLIGEGIVFPVV
DTMQIEGDYQQEQAKGFINWLKGKRPESIRLANTRLRYGLPSYPPHHALTDAIATAELFQAQVRYHFSPHDPIRKLWL
>Mature_238_residues
MIPHAPQEILNWPSFFKHKQEISKDKRLKNFYKTGTYEEETPLSDIEFVALDFETTGLDANQNSIISIGLVPFTLERIFC
RQSQHWFVKAQDSLEENSVVIHGITHSDLQGAPDLRRILEQVLDALAGKVVVVHYRRIERDFFDANLRSLIGEGIVFPVV
DTMQIEGDYQQEQAKGFINWLKGKRPESIRLANTRLRYGLPSYPPHHALTDAIATAELFQAQVRYHFSPHDPIRKLWL

Specific function: Unknown

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 27495; Mature: 27495

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPHAPQEILNWPSFFKHKQEISKDKRLKNFYKTGTYEEETPLSDIEFVALDFETTGLDA
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCC
NQNSIISIGLVPFTLERIFCRQSQHWFVKAQDSLEENSVVIHGITHSDLQGAPDLRRILE
CCCCEEEEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHH
QVLDALAGKVVVVHYRRIERDFFDANLRSLIGEGIVFPVVDTMQIEGDYQQEQAKGFINW
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEECCCHHHHHHHHHHHH
LKGKRPESIRLANTRLRYGLPSYPPHHALTDAIATAELFQAQVRYHFSPHDPIRKLWL
HCCCCCCCEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
>Mature Secondary Structure
MIPHAPQEILNWPSFFKHKQEISKDKRLKNFYKTGTYEEETPLSDIEFVALDFETTGLDA
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCC
NQNSIISIGLVPFTLERIFCRQSQHWFVKAQDSLEENSVVIHGITHSDLQGAPDLRRILE
CCCCEEEEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHH
QVLDALAGKVVVVHYRRIERDFFDANLRSLIGEGIVFPVVDTMQIEGDYQQEQAKGFINW
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEECEEEEEECCCHHHHHHHHHHHH
LKGKRPESIRLANTRLRYGLPSYPPHHALTDAIATAELFQAQVRYHFSPHDPIRKLWL
HCCCCCCCEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA