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The map label for this gene is agmR [H]

Identifier: 59712981

GI number: 59712981

Start: 2661301

End: 2661930

Strand: Direct

Name: agmR [H]

Synonym: VF_2374

Alternate gene names: 59712981

Gene position: 2661301-2661930 (Clockwise)

Preceding gene: 172087768

Following gene: 59712982

Centisome position: 91.85

GC content: 39.84

Gene sequence:

>630_bases
ATGGACGACAACTACACTATTATCATTGCAGACGATCACCCCTTATTTCGCAATGCACTTTTTCAATCTATCCACATGGC
AATCAGTGGTGCAAACCTACTAGAAGCTGATTCATTAGAGGCGTTATTAAAAGTATTAGAGAAAGAACCTGAACCTGATT
TACTGCTCTTAGACTTAAAAATGCCGGGTAGTAATGGCATGTCAGGATTAATCCAATTACGCTCTCAATATCCTGATTTA
CCGATTGTGGTTGTATCAGCGAGTGAAGAAGCAAGTATTGTCTCTCAAGTTAAAACCCATGGTGCATTCGGTTTTATTCC
TAAATCCAGTGACATGAAGTCGCTTATCGGGGCACTTAATCAAATTTTAGCGGGGGATTCCTATTTTCCTGCAGGAGCAA
TTAAGAACTCAGCAGCTTGCGATGATTTAGCGACAAAAATAGCCGCGCTAACGCCTCAGCAATATAAAGTACTCGGAATG
TTGTCAGATGGGTTGCTCAATAAACAAATTGCGTATGATTTAGACGTATCAGAAGCCACAATAAAAGCACACATGACAGC
AATATTTAGAAAGTTAGGAGTGAAGAATCGCACTCAAGCCGTCATTCTTTTACAACAAACGGAAAGTTAA

Upstream 100 bases:

>100_bases
AATGAGTTAGAGAGGCAGCTCAGATTTTAGCGACTAAAAATTGCTCAAAACACAAGAGGATGTTAATTTTATTTTATAAC
TTATAAGGAATCTTGTAGCC

Downstream 100 bases:

>100_bases
CCAAGATATAACACTCTAGACGCTAAAATAAATTAAACTCTCTTCTACGCTATACCAATCAATATGACTTCACATCATTG
ATTGGTATTCCATCCCTCTG

Product: two-component response regulator

Products: NA

Alternate protein names: Protein AgmR [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MDDNYTIIIADDHPLFRNALFQSIHMAISGANLLEADSLEALLKVLEKEPEPDLLLLDLKMPGSNGMSGLIQLRSQYPDL
PIVVVSASEEASIVSQVKTHGAFGFIPKSSDMKSLIGALNQILAGDSYFPAGAIKNSAACDDLATKIAALTPQQYKVLGM
LSDGLLNKQIAYDLDVSEATIKAHMTAIFRKLGVKNRTQAVILLQQTES

Sequences:

>Translated_209_residues
MDDNYTIIIADDHPLFRNALFQSIHMAISGANLLEADSLEALLKVLEKEPEPDLLLLDLKMPGSNGMSGLIQLRSQYPDL
PIVVVSASEEASIVSQVKTHGAFGFIPKSSDMKSLIGALNQILAGDSYFPAGAIKNSAACDDLATKIAALTPQQYKVLGM
LSDGLLNKQIAYDLDVSEATIKAHMTAIFRKLGVKNRTQAVILLQQTES
>Mature_209_residues
MDDNYTIIIADDHPLFRNALFQSIHMAISGANLLEADSLEALLKVLEKEPEPDLLLLDLKMPGSNGMSGLIQLRSQYPDL
PIVVVSASEEASIVSQVKTHGAFGFIPKSSDMKSLIGALNQILAGDSYFPAGAIKNSAACDDLATKIAALTPQQYKVLGM
LSDGLLNKQIAYDLDVSEATIKAHMTAIFRKLGVKNRTQAVILLQQTES

Specific function: Positive activator for glycerol metabolism [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786747, Length=191, Percent_Identity=26.7015706806283, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=31.5533980582524, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789937, Length=198, Percent_Identity=26.7676767676768, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1787473, Length=209, Percent_Identity=33.4928229665072, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788712, Length=193, Percent_Identity=29.0155440414508, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=28.2926829268293, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788222, Length=193, Percent_Identity=22.279792746114, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22555; Mature: 22555

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDNYTIIIADDHPLFRNALFQSIHMAISGANLLEADSLEALLKVLEKEPEPDLLLLDLK
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEE
MPGSNGMSGLIQLRSQYPDLPIVVVSASEEASIVSQVKTHGAFGFIPKSSDMKSLIGALN
CCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHH
QILAGDSYFPAGAIKNSAACDDLATKIAALTPQQYKVLGMLSDGLLNKQIAYDLDVSEAT
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHEEEHHHCCCCCCCEEEECCCCHHH
IKAHMTAIFRKLGVKNRTQAVILLQQTES
HHHHHHHHHHHHCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MDDNYTIIIADDHPLFRNALFQSIHMAISGANLLEADSLEALLKVLEKEPEPDLLLLDLK
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEE
MPGSNGMSGLIQLRSQYPDLPIVVVSASEEASIVSQVKTHGAFGFIPKSSDMKSLIGALN
CCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHH
QILAGDSYFPAGAIKNSAACDDLATKIAALTPQQYKVLGMLSDGLLNKQIAYDLDVSEAT
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHEEEHHHCCCCCCCEEEECCCCHHH
IKAHMTAIFRKLGVKNRTQAVILLQQTES
HHHHHHHHHHHHCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1938886; 10984043 [H]