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The map label for this gene is hflX [H]

Identifier: 59712929

GI number: 59712929

Start: 2609065

End: 2610366

Strand: Reverse

Name: hflX [H]

Synonym: VF_2322

Alternate gene names: 59712929

Gene position: 2610366-2609065 (Counterclockwise)

Preceding gene: 59712930

Following gene: 59712928

Centisome position: 90.09

GC content: 40.94

Gene sequence:

>1302_bases
TTGTTTGACCGTTATGAATCCGGTGAACAGGCTATTCTTGTGCACATTGACTTTACCTATCAAGGGGAGATTGAAGATCT
TAACGAATGTAAAATGTTAATTTCTTCTGCGGGGGTAAACACAGTAGGTGTTGTGACGGGAACCCGTCAATCTCCACTCC
CTAAATATTATGTTGGTGAAGGCAAGGCACAAGAAATTGCCGATGCTGTTCGAGCTAATAACGCAGATATCGTGATTTTT
AATCACGCATTATCTCCGGCTCAAGAACGAAATTTAGAACAATTATGTCAGTGTCGAGTAATAGATCGTACGGGTCTAAT
ACTGGATATATTTGCTCAACGAGCACGAACTTACGAAGGTAAGTTGCAAGTTGAGTTAGCACAATTACGTCATATCTCTA
CGCGATTAATCCGTGGTTGGACTCACCTTGAACGTCAAAAAGGCGGTATAGGTTTACGTGGTCCAGGTGAGACTCAGTTA
GAGACTGATAGACGATTGTTGCGTGAACGTATTAAAGCGATTCTTCGTAGGTTAGGCAAAGTAGCTAAACAACGTGAGCA
AGGGCGTCGAGCTCGACACCGTGCAGAAATTCCAACCATTTCTTTAGTCGGTTACACCAACGCAGGTAAATCTACGTTGT
TTAATCGAATTACAGAGGCTGGGGTTTATGCTGCTGACCAATTGTTTGCGACCTTGGATCCAACATTACGAAAAATAGAA
GTTGCCGATGTAGGAACCTCAATTCTTGCTGATACGGTAGGTTTTATTCGTCATTTACCACATGATTTGGTTGCCGCTTT
TAAAGCGACATTACAAGAAACACAAGAAGCTAATATCTTGTTACATGTTGTAGATGCGAGTGATGAACGTTTTCGTGAGA
ATATTGAAGCAGTAGATATTGTTCTTGAAGAGATAGATGCCAATGAGGTACCGACTCTTCTTGTAATGAATAAGATTGAT
AACTTAGAAGATCAACAACCACGAATTGAGCGTGATGAGGAAGGTATACCTCGATGTGTTTGGGTTTCCGCGATGGAAGG
CAAAGGCATAGAGTTATTATTCCAAGCATTAACAGAGCGCTTATCTGGACAGATGGTTGAGCATTCTTTGCTTTTACCGC
CTGATTGGGTTGGACGTCTTCGAAGTAAATTCTTTCAAATGCAATGTATTCTTAACGAAGAATATCAAGATGATGGCAGT
TTGCTGGTTGATGTACGTATGCAGCAAGTTGATTGGTCTAAGTTGGAAAAACGTGAAGATGCTCCCTTAAGTGATTTTAT
TATTACTAAAGAGAGTGCATAG

Upstream 100 bases:

>100_bases
CCATCACTCAGCGAGTGATCGTCCACAAGGCGAGCGTCCACAAGAAAAAACTGAAGAGTAATACTATTCTAGAATAGTTA
ATCAGTTAAGGAGTTAACGC

Downstream 100 bases:

>100_bases
AATTCTTTATCTTCATAATTATCATGGAGTTTTCTAATGGCGTGGAATGAGCCTGGAAATAACAACAATAACGGCGGCGA
TAAAGACCCTTGGGGTAATA

Product: putative GTPase HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MFDRYESGEQAILVHIDFTYQGEIEDLNECKMLISSAGVNTVGVVTGTRQSPLPKYYVGEGKAQEIADAVRANNADIVIF
NHALSPAQERNLEQLCQCRVIDRTGLILDIFAQRARTYEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRERIKAILRRLGKVAKQREQGRRARHRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKIE
VADVGTSILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDIVLEEIDANEVPTLLVMNKID
NLEDQQPRIERDEEGIPRCVWVSAMEGKGIELLFQALTERLSGQMVEHSLLLPPDWVGRLRSKFFQMQCILNEEYQDDGS
LLVDVRMQQVDWSKLEKREDAPLSDFIITKESA

Sequences:

>Translated_433_residues
MFDRYESGEQAILVHIDFTYQGEIEDLNECKMLISSAGVNTVGVVTGTRQSPLPKYYVGEGKAQEIADAVRANNADIVIF
NHALSPAQERNLEQLCQCRVIDRTGLILDIFAQRARTYEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRERIKAILRRLGKVAKQREQGRRARHRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKIE
VADVGTSILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDIVLEEIDANEVPTLLVMNKID
NLEDQQPRIERDEEGIPRCVWVSAMEGKGIELLFQALTERLSGQMVEHSLLLPPDWVGRLRSKFFQMQCILNEEYQDDGS
LLVDVRMQQVDWSKLEKREDAPLSDFIITKESA
>Mature_433_residues
MFDRYESGEQAILVHIDFTYQGEIEDLNECKMLISSAGVNTVGVVTGTRQSPLPKYYVGEGKAQEIADAVRANNADIVIF
NHALSPAQERNLEQLCQCRVIDRTGLILDIFAQRARTYEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRERIKAILRRLGKVAKQREQGRRARHRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKIE
VADVGTSILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDIVLEEIDANEVPTLLVMNKID
NLEDQQPRIERDEEGIPRCVWVSAMEGKGIELLFQALTERLSGQMVEHSLLLPPDWVGRLRSKFFQMQCILNEEYQDDGS
LLVDVRMQQVDWSKLEKREDAPLSDFIITKESA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=219, Percent_Identity=36.0730593607306, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI310133118, Length=221, Percent_Identity=36.1990950226244, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI310124269, Length=201, Percent_Identity=36.81592039801, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI310124267, Length=201, Percent_Identity=36.81592039801, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI310124171, Length=201, Percent_Identity=36.81592039801, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI310124169, Length=201, Percent_Identity=36.81592039801, Blast_Score=115, Evalue=8e-26,
Organism=Escherichia coli, GI1790615, Length=428, Percent_Identity=71.7289719626168, Blast_Score=624, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17561038, Length=342, Percent_Identity=25.1461988304094, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24650079, Length=282, Percent_Identity=30.8510638297872, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49006; Mature: 49006

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYESGEQAILVHIDFTYQGEIEDLNECKMLISSAGVNTVGVVTGTRQSPLPKYYVGE
CCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECC
GKAQEIADAVRANNADIVIFNHALSPAQERNLEQLCQCRVIDRTGLILDIFAQRARTYEG
CHHHHHHHHHHCCCCCEEEEECCCCCHHHCCHHHHHHEEHHCCCCHHHHHHHHHHHCCCC
KLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRERIKAILRRLGK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARHRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKIE
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEE
VADVGTSILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDI
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
VLEEIDANEVPTLLVMNKIDNLEDQQPRIERDEEGIPRCVWVSAMEGKGIELLFQALTER
HHHHCCCCCCCCEEEEHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
LSGQMVEHSLLLPPDWVGRLRSKFFQMQCILNEEYQDDGSLLVDVRMQQVDWSKLEKRED
HCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHCCHHHHHHHCC
APLSDFIITKESA
CCCHHEEEECCCC
>Mature Secondary Structure
MFDRYESGEQAILVHIDFTYQGEIEDLNECKMLISSAGVNTVGVVTGTRQSPLPKYYVGE
CCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECC
GKAQEIADAVRANNADIVIFNHALSPAQERNLEQLCQCRVIDRTGLILDIFAQRARTYEG
CHHHHHHHHHHCCCCCEEEEECCCCCHHHCCHHHHHHEEHHCCCCHHHHHHHHHHHCCCC
KLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRERIKAILRRLGK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARHRAEIPTISLVGYTNAGKSTLFNRITEAGVYAADQLFATLDPTLRKIE
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEE
VADVGTSILADTVGFIRHLPHDLVAAFKATLQETQEANILLHVVDASDERFRENIEAVDI
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
VLEEIDANEVPTLLVMNKIDNLEDQQPRIERDEEGIPRCVWVSAMEGKGIELLFQALTER
HHHHCCCCCCCCEEEEHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
LSGQMVEHSLLLPPDWVGRLRSKFFQMQCILNEEYQDDGSLLVDVRMQQVDWSKLEKRED
HCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHCCHHHHHHHCC
APLSDFIITKESA
CCCHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]