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The map label for this gene is nsrR

Identifier: 59712922

GI number: 59712922

Start: 2602451

End: 2602876

Strand: Reverse

Name: nsrR

Synonym: VF_2315

Alternate gene names: 59712922

Gene position: 2602876-2602451 (Counterclockwise)

Preceding gene: 59712924

Following gene: 59712921

Centisome position: 89.83

GC content: 37.56

Gene sequence:

>426_bases
ATGCAATTAACAAATTTCACTGATTTTGGCTTAAGAGCCTTGATTTATTTAGGGTCATTACCAGAAGGTGAATTGACTAG
CATTACTGTGGTTACTGAAACTTTTGATGTATCACGTAACCACATGGTGAAAATAATTAACAAATTAGGCCAAGAAGGGT
ATGTCAAAACCATTCGAGGTAAAAATGGCGGGATCTGCTTAGGAAAACCTGCGGATCAAATCATTATTGGTGATGTCATT
CGAGCTATTGAACCATTACAGGTGGTTAACTGTGCTCCTGAGTTTTGCCATATTACACCGGCATGTCGTTTAAAAGGTGC
ATTAGCGAAAGCAAAGCAAGCGTTTTTAGATGAGCTTGATAAACATACGATTCAAGACATGCTTACCGATAACAGTGAGT
TACTCATTCTTTTGAAGCGAATTTAA

Upstream 100 bases:

>100_bases
TACCTTTAAAGGTGTATTTATAATGTATGTTATAAGTTGTATCTAAAATATATCTTTTAGTCAAGAGAAGAATTACAATG
AAAAAAGAGAAGGAGAGGAT

Downstream 100 bases:

>100_bases
GACTTGAATTCCAGATCCTTTCCTATCTGTTATAGGCATACTCAGGTACAATATAACTATATTTCTTGTCTCTCCGACTA
AGCAGGTCAGCCTATGTCTA

Product: transcriptional repressor NsrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MQLTNFTDFGLRALIYLGSLPEGELTSITVVTETFDVSRNHMVKIINKLGQEGYVKTIRGKNGGICLGKPADQIIIGDVI
RAIEPLQVVNCAPEFCHITPACRLKGALAKAKQAFLDELDKHTIQDMLTDNSELLILLKRI

Sequences:

>Translated_141_residues
MQLTNFTDFGLRALIYLGSLPEGELTSITVVTETFDVSRNHMVKIINKLGQEGYVKTIRGKNGGICLGKPADQIIIGDVI
RAIEPLQVVNCAPEFCHITPACRLKGALAKAKQAFLDELDKHTIQDMLTDNSELLILLKRI
>Mature_141_residues
MQLTNFTDFGLRALIYLGSLPEGELTSITVVTETFDVSRNHMVKIINKLGQEGYVKTIRGKNGGICLGKPADQIIIGDVI
RAIEPLQVVNCAPEFCHITPACRLKGALAKAKQAFLDELDKHTIQDMLTDNSELLILLKRI

Specific function: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790621, Length=138, Percent_Identity=65.9420289855072, Blast_Score=198, Evalue=1e-52,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NSRR_VIBF1 (Q5E2D6)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205698.1
- ProteinModelPortal:   Q5E2D6
- STRING:   Q5E2D6
- GeneID:   3279451
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_2315
- NMPDR:   fig|312309.3.peg.2315
- eggNOG:   COG1959
- HOGENOM:   HBG725923
- OMA:   ITNSCQF
- PhylomeDB:   Q5E2D6
- ProtClustDB:   PRK11014
- BioCyc:   VFIS312309:VF2315-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01177
- InterPro:   IPR000944
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR00738

Pfam domain/function: PF02082 Rrf2

EC number: NA

Molecular weight: Translated: 15564; Mature: 15564

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS01332 HTH_RRF2_1; PS51197 HTH_RRF2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTNFTDFGLRALIYLGSLPEGELTSITVVTETFDVSRNHMVKIINKLGQEGYVKTIRG
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECC
KNGGICLGKPADQIIIGDVIRAIEPLQVVNCAPEFCHITPACRLKGALAKAKQAFLDELD
CCCCEEECCCCCHHHHHHHHHHHCHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KHTIQDMLTDNSELLILLKRI
HHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MQLTNFTDFGLRALIYLGSLPEGELTSITVVTETFDVSRNHMVKIINKLGQEGYVKTIRG
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECC
KNGGICLGKPADQIIIGDVIRAIEPLQVVNCAPEFCHITPACRLKGALAKAKQAFLDELD
CCCCEEECCCCCHHHHHHHHHHHCHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KHTIQDMLTDNSELLILLKRI
HHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA