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The map label for this gene is pabA [H]

Identifier: 59712892

GI number: 59712892

Start: 2568001

End: 2568579

Strand: Reverse

Name: pabA [H]

Synonym: VF_2285

Alternate gene names: 59712892

Gene position: 2568579-2568001 (Counterclockwise)

Preceding gene: 59712893

Following gene: 59712891

Centisome position: 88.65

GC content: 38.51

Gene sequence:

>579_bases
ATGCTATTAATGATCGACAATTATGATTCGTTTACTTACAACCTATATCAGTATTTCTGTGAATTGGGTGTTGAAGTAAA
AGTCGTTCGTAATGATGAAATCGATATTGTAGGTATTGAAGCACTAAACCCTTCTCATTTAGTTATCTCCCCAGGTCCAT
GTACACCAAATGAAGCTGGCATTTCATTAGAAGCCATTAAGTATTTCGCCAGTAAATTACCGATTCTTGGCGTATGCTTA
GGCCATCAATCCATTGCTCAAGTATTTGGTGGGGATGTGGTTCGAGCTAAAAAAGTCATGCACGGTAAAACTTCTGCAAT
TACTCACACTAGCCGTAGTGTTTTCAAAGGGTTAAATAACCCGCTTACGGTGACACGTTACCACTCATTGATTGTGAAAA
AAGAGACGCTACCAGAGTGCTTTGAAGTGACTGCATGGACAGAAACTGAATCTGGTGATATGGATGAGATCATGGGATTT
TGTCATAAAAGTTTACCTATTGAAGGCGTACAGTTTCACCCTGAGTCTATTTTGACTGAACAAGGTCATGAGATCTTACG
TAACTTTATCCAAAAATAA

Upstream 100 bases:

>100_bases
ACTCGCCCATAGCGCCTTATTGTATTTAAGTTCCATCAATTGCTCGTAGGCTGACCTGCGAGCAATTTTTATTTTATCCA
TCTTATAAAGTAGTTCTTTT

Downstream 100 bases:

>100_bases
TTATTACCTCATAATGATGAGCGATCTAGCTCACCCTTCTTACTTTTTCTTTACTTTTATAACGTTTTTATTTTTGTGCA
ACTTTATGCATAGGGTGACG

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLLMIDNYDSFTYNLYQYFCELGVEVKVVRNDEIDIVGIEALNPSHLVISPGPCTPNEAGISLEAIKYFASKLPILGVCL
GHQSIAQVFGGDVVRAKKVMHGKTSAITHTSRSVFKGLNNPLTVTRYHSLIVKKETLPECFEVTAWTETESGDMDEIMGF
CHKSLPIEGVQFHPESILTEQGHEILRNFIQK

Sequences:

>Translated_192_residues
MLLMIDNYDSFTYNLYQYFCELGVEVKVVRNDEIDIVGIEALNPSHLVISPGPCTPNEAGISLEAIKYFASKLPILGVCL
GHQSIAQVFGGDVVRAKKVMHGKTSAITHTSRSVFKGLNNPLTVTRYHSLIVKKETLPECFEVTAWTETESGDMDEIMGF
CHKSLPIEGVQFHPESILTEQGHEILRNFIQK
>Mature_192_residues
MLLMIDNYDSFTYNLYQYFCELGVEVKVVRNDEIDIVGIEALNPSHLVISPGPCTPNEAGISLEAIKYFASKLPILGVCL
GHQSIAQVFGGDVVRAKKVMHGKTSAITHTSRSVFKGLNNPLTVTRYHSLIVKKETLPECFEVTAWTETESGDMDEIMGF
CHKSLPIEGVQFHPESILTEQGHEILRNFIQK

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=192, Percent_Identity=65.625, Blast_Score=279, Evalue=6e-77,
Organism=Escherichia coli, GI1787517, Length=189, Percent_Identity=41.7989417989418, Blast_Score=138, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI133901714, Length=146, Percent_Identity=32.8767123287671, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71992710, Length=146, Percent_Identity=32.8767123287671, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71992717, Length=146, Percent_Identity=32.8767123287671, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=191, Percent_Identity=49.738219895288, Blast_Score=199, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=214, Percent_Identity=31.3084112149533, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323873, Length=147, Percent_Identity=31.9727891156463, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21428; Mature: 21428

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTYNLYQYFCELGVEVKVVRNDEIDIVGIEALNPSHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCEEEEEEEECCCCEEEEECCCCCCCCCC
ISLEAIKYFASKLPILGVCLGHQSIAQVFGGDVVRAKKVMHGKTSAITHTSRSVFKGLNN
CHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCC
PLTVTRYHSLIVKKETLPECFEVTAWTETESGDMDEIMGFCHKSLPIEGVQFHPESILTE
CEEEEEHHHHHHHHCCCHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHH
QGHEILRNFIQK
HHHHHHHHHHCC
>Mature Secondary Structure
MLLMIDNYDSFTYNLYQYFCELGVEVKVVRNDEIDIVGIEALNPSHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCEEEEEEEECCCCEEEEECCCCCCCCCC
ISLEAIKYFASKLPILGVCLGHQSIAQVFGGDVVRAKKVMHGKTSAITHTSRSVFKGLNN
CHHHHHHHHHHCCCEEEEECCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCC
PLTVTRYHSLIVKKETLPECFEVTAWTETESGDMDEIMGFCHKSLPIEGVQFHPESILTE
CEEEEEHHHHHHHHCCCHHHHHEEEECCCCCCCHHHHHHHHHHCCCCCCEEECHHHHHHH
QGHEILRNFIQK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2404959; 659439 [H]