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The map label for this gene is argD [H]

Identifier: 59712891

GI number: 59712891

Start: 2566482

End: 2567696

Strand: Reverse

Name: argD [H]

Synonym: VF_2284

Alternate gene names: 59712891

Gene position: 2567696-2566482 (Counterclockwise)

Preceding gene: 59712892

Following gene: 59712890

Centisome position: 88.62

GC content: 42.06

Gene sequence:

>1215_bases
ATGACGACCAATTCACAAGTTGAACGTAAAGATTTTAATGATGTAATGGTACCTTGTTATAACCCAATGGAAGTGATCCC
TGTAAAAGGCGAGGGAGCTCGAGTATGGGACCAAACGGGTAAGGATTACATTGATTTTGCTGGAGGTATTGCAGTGAGCT
GTTTAGGCCACTGTCATCCTATTATGGTTAATGCACTACAAGAGCAGTCACAAAAGTTGTGGCATTTAAGTAATGTTATG
ACCAATGAGCCAGCTATTCGACTCGCTAAAAAGTTAACTGAAGTCTCTTTTGCTGAAAAAGTATTTTTTGCTAACTCAGG
TGCTGAAGCGAATGAAGCGGCGTTGAAGTTAGCGCGTCGTTGGGCTGTGGATGTTCATAGCGAAGAAAAGAGTGAAATAA
TTGCTTTTAAACAAGGCTTCCATGGTCGAACTTTCTTTACTGTAACCGTTGGCGGTCAAGCTGCGTATTCTGATGGTTTT
GGTCCTAAACCGGGTGATATTACTCATTTAGAATACAATAACCTTGCTGAACTTGAAGCACACATGTCTGATAAAACGTG
TGCGGTAATGATGGAGCCATTACAGGGAGAAGGGGGGATAGTTTCGCCTACTTCTGAATTTGTAAAAGGCGTAAAAGCAT
TATGTGAAAAGTACAATGCACTGCTGATTTTTGATGAAGTTCAAACAGGTAATGGCCGAACTGGTGATTTTTATGCCTAT
CAAGGATTAGGTGTTACACCTGATATTCTCAGTACTGCTAAATCACTTGGTGGTGGTTTCCCTATCGGAGCTATGCTCAC
TACGACTGAATTAGCTCAGCATTTAAAAGTAGGAACCCATGGTTCGACTTATGGTGGTAATCCACTTGCTTGTGCTATTG
CGGAAGCGGTGGTTGAAGAAGTATCAAAACCTGAAGTTTTAAATGGCGTTAAAGAGCGCGAGCAATGGTTCCGTTCTGGT
CTAGAGGCATTAAACGCCAAATATCATATGTTTTCAGAGATCCGAGGCAAAGGTTTATTGCTTGGTGCTGCTCTAAATGA
AGAGTGGCAAGGTCGAGCTCGTGACATATTGGTGGCAGCGGGAGAGCAAGGTTTGATGGTACTTGTTGCTGGCGTTAATG
TGGTTCGATTTACCCCATCATTAGTGATTACAAAAGAAGAAGTTGAGTTAGGTTTTGAGCGCTTAGATAAGGCGCTTGCT
TCTCTAACGAAATAA

Upstream 100 bases:

>100_bases
TAATGCTTTTTTAGTTCAAAAAAAGAATTTTGTGCTATTGAAAAGGTTAACGGTTTGTAAATATTATGCAGGATAACGGC
ATACGCAGAAGGAAAGTGTG

Downstream 100 bases:

>100_bases
CGCTTTAAAGAATATTAGGCAACTCATGGTCGAGTTGCCTTTGTTTTTGGCATCGGAGGGAATATTGATGCTTGTTATCC
GTCCTATTACTCAAGAAGAT

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTTNSQVERKDFNDVMVPCYNPMEVIPVKGEGARVWDQTGKDYIDFAGGIAVSCLGHCHPIMVNALQEQSQKLWHLSNVM
TNEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARRWAVDVHSEEKSEIIAFKQGFHGRTFFTVTVGGQAAYSDGF
GPKPGDITHLEYNNLAELEAHMSDKTCAVMMEPLQGEGGIVSPTSEFVKGVKALCEKYNALLIFDEVQTGNGRTGDFYAY
QGLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAIAEAVVEEVSKPEVLNGVKEREQWFRSG
LEALNAKYHMFSEIRGKGLLLGAALNEEWQGRARDILVAAGEQGLMVLVAGVNVVRFTPSLVITKEEVELGFERLDKALA
SLTK

Sequences:

>Translated_404_residues
MTTNSQVERKDFNDVMVPCYNPMEVIPVKGEGARVWDQTGKDYIDFAGGIAVSCLGHCHPIMVNALQEQSQKLWHLSNVM
TNEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARRWAVDVHSEEKSEIIAFKQGFHGRTFFTVTVGGQAAYSDGF
GPKPGDITHLEYNNLAELEAHMSDKTCAVMMEPLQGEGGIVSPTSEFVKGVKALCEKYNALLIFDEVQTGNGRTGDFYAY
QGLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAIAEAVVEEVSKPEVLNGVKEREQWFRSG
LEALNAKYHMFSEIRGKGLLLGAALNEEWQGRARDILVAAGEQGLMVLVAGVNVVRFTPSLVITKEEVELGFERLDKALA
SLTK
>Mature_403_residues
TTNSQVERKDFNDVMVPCYNPMEVIPVKGEGARVWDQTGKDYIDFAGGIAVSCLGHCHPIMVNALQEQSQKLWHLSNVMT
NEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARRWAVDVHSEEKSEIIAFKQGFHGRTFFTVTVGGQAAYSDGFG
PKPGDITHLEYNNLAELEAHMSDKTCAVMMEPLQGEGGIVSPTSEFVKGVKALCEKYNALLIFDEVQTGNGRTGDFYAYQ
GLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAIAEAVVEEVSKPEVLNGVKEREQWFRSGL
EALNAKYHMFSEIRGKGLLLGAALNEEWQGRARDILVAAGEQGLMVLVAGVNVVRFTPSLVITKEEVELGFERLDKALAS
LTK

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=34.1085271317829, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=34.4370860927152, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI13994255, Length=422, Percent_Identity=28.9099526066351, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI37574042, Length=414, Percent_Identity=26.8115942028986, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI226442709, Length=380, Percent_Identity=27.3684210526316, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI24119277, Length=419, Percent_Identity=25.0596658711217, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI226442705, Length=414, Percent_Identity=25.6038647342995, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI188536080, Length=434, Percent_Identity=23.2718894009217, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI38679950, Length=434, Percent_Identity=23.2718894009217, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI38679946, Length=434, Percent_Identity=23.2718894009217, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789759, Length=400, Percent_Identity=56.25, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1788044, Length=392, Percent_Identity=56.8877551020408, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=33.0827067669173, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI145693181, Length=384, Percent_Identity=33.3333333333333, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=33.5012594458438, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786349, Length=307, Percent_Identity=31.9218241042345, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786991, Length=295, Percent_Identity=31.5254237288136, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=389, Percent_Identity=36.5038560411311, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=30.9633027522936, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI25144274, Length=279, Percent_Identity=34.4086021505376, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=416, Percent_Identity=26.4423076923077, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=26.6514806378132, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71981843, Length=158, Percent_Identity=35.4430379746835, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=35.6060606060606, Blast_Score=257, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6323470, Length=401, Percent_Identity=35.9102244389027, Blast_Score=230, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6324386, Length=335, Percent_Identity=29.2537313432836, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=427, Percent_Identity=25.2927400468384, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357415, Length=390, Percent_Identity=35.6410256410256, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI161085790, Length=420, Percent_Identity=30.2380952380952, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28574759, Length=420, Percent_Identity=29.7619047619048, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=28.2296650717703, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281366494, Length=435, Percent_Identity=22.9885057471264, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667139, Length=435, Percent_Identity=22.9885057471264, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24667143, Length=435, Percent_Identity=22.9885057471264, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43832; Mature: 43701

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNSQVERKDFNDVMVPCYNPMEVIPVKGEGARVWDQTGKDYIDFAGGIAVSCLGHCHP
CCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCHHHHCCCHHHHHCCCHHHHHHHCHHH
IMVNALQEQSQKLWHLSNVMTNEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
WAVDVHSEEKSEIIAFKQGFHGRTFFTVTVGGQAAYSDGFGPKPGDITHLEYNNLAELEA
HHHCCCCCCHHHEEEECCCCCCCEEEEEEECCCEEECCCCCCCCCCEEEECCCCHHHHHH
HMSDKTCAVMMEPLQGEGGIVSPTSEFVKGVKALCEKYNALLIFDEVQTGNGRTGDFYAY
HCCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEE
QGLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAIAEAVVEE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
VSKPEVLNGVKEREQWFRSGLEALNAKYHMFSEIRGKGLLLGAALNEEWQGRARDILVAA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEE
GEQGLMVLVAGVNVVRFTPSLVITKEEVELGFERLDKALASLTK
CCCCCEEEEECCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTNSQVERKDFNDVMVPCYNPMEVIPVKGEGARVWDQTGKDYIDFAGGIAVSCLGHCHP
CCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCHHHHCCCHHHHHCCCHHHHHHHCHHH
IMVNALQEQSQKLWHLSNVMTNEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
WAVDVHSEEKSEIIAFKQGFHGRTFFTVTVGGQAAYSDGFGPKPGDITHLEYNNLAELEA
HHHCCCCCCHHHEEEECCCCCCCEEEEEEECCCEEECCCCCCCCCCEEEECCCCHHHHHH
HMSDKTCAVMMEPLQGEGGIVSPTSEFVKGVKALCEKYNALLIFDEVQTGNGRTGDFYAY
HCCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEEE
QGLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAIAEAVVEE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
VSKPEVLNGVKEREQWFRSGLEALNAKYHMFSEIRGKGLLLGAALNEEWQGRARDILVAA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEEE
GEQGLMVLVAGVNVVRFTPSLVITKEEVELGFERLDKALASLTK
CCCCCEEEEECCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]