Click here to switch to the map view.

The map label for this gene is ygjD [H]

Identifier: 59712856

GI number: 59712856

Start: 2524468

End: 2525484

Strand: Reverse

Name: ygjD [H]

Synonym: VF_2249

Alternate gene names: 59712856

Gene position: 2525484-2524468 (Counterclockwise)

Preceding gene: 172087763

Following gene: 59712854

Centisome position: 87.16

GC content: 42.58

Gene sequence:

>1017_bases
ATGCGAATTTTAGGCATTGAAACCTCGTGTGATGAAACGGGTGTTGCGATTTATGATGATGAAAAAGGGTTATTAGCTCA
TCAGCTGTATAGCCAAGTAAAACTGCATGCTGATTACGGCGGTGTAGTGCCTGAATTGGCTTCTCGTGATCATGTTAAAA
AGACCATTCCGTTGATTAAAGCAGCACTAAATGATGCTGGTTTAACCAAAGATGATATCGATGGGATTGCGTATACTGCT
GGCCCTGGTCTAGTGGGCGCCTTACTTGTTGGTTCAACTATTGGCCGAAGCATTGCTTATGCATGGGATGTTCCTGCAAT
TCCTGTCCATCATATGGAAGGGCATTTGCTTGCTCCAATGCTTGAGGATGAGCCACCAGCATTTCCATTTGTTGCTTTAC
TTGTTTCTGGTGGTCACACCATGATGGTTGAAGTAAAAGGCATTGGTGAATATCAGATCCTTGGTGAATCTGTGGATGAT
GCGGCTGGTGAAGCATTTGATAAAACAGCAAAACTGATGGGATTAGATTACCCTGGTGGTCCATTACTTTCTAAATTAGC
AGAGAGTGGTACAAAAGGGCGTTTTAAATTCCCACGCCCTATGACCGATCGCCCTGGCTTGGATTTTAGTTTTTCTGGTT
TGAAAACATTTGCTGCAAATACGATTCGTGGCAATGAAGATGATCTACAAACACGAGCTGATATTGCTTTTGCTTTTCAG
GAAGCGGTAGTTGATACATTAGCGATTAAATGTCGCCGAGCTTTAAAGCAAACAGGCATGAAACGTTTAGTGATGGCTGG
TGGCGTAAGTGCGAATAAATATTTACGCCAAGAACTAGAAGTGATGATGAAGAAAATTGGTGGTGAGGTGTATTACCCTC
GAACTGAATTTTGTACCGATAATGGTGCCATGATCGCTTACGCTGGAATTCAACGTTTGAAAAACGGCGAAACGACAGAT
TTAGCGGTTCAAGCTAAACCTCGTTGGCCAATAGATCAGTTAGCGCCAATTAAATAA

Upstream 100 bases:

>100_bases
ATTTCTTTGTTTATTTTGCCTTCTTAAGGCATCTCCTTGCTTGAGGTAGCTCAGGGATGTAGGTAATATGGCGATAAATT
AACAGGTAGCTGAGAAAAAT

Downstream 100 bases:

>100_bases
AAAGTGATCCGTTTGGATCATAAAAGATCGTTATCTATATAAAGGGGCTATTTAGTCCCTTTTTCTTTGCCATATTTTTG
TCTCTTTGCCTTCAAAGAAA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIKAALNDAGLTKDDIDGIAYTA
GPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPMLEDEPPAFPFVALLVSGGHTMMVEVKGIGEYQILGESVDD
AAGEAFDKTAKLMGLDYPGGPLLSKLAESGTKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRGNEDDLQTRADIAFAFQ
EAVVDTLAIKCRRALKQTGMKRLVMAGGVSANKYLRQELEVMMKKIGGEVYYPRTEFCTDNGAMIAYAGIQRLKNGETTD
LAVQAKPRWPIDQLAPIK

Sequences:

>Translated_338_residues
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIKAALNDAGLTKDDIDGIAYTA
GPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPMLEDEPPAFPFVALLVSGGHTMMVEVKGIGEYQILGESVDD
AAGEAFDKTAKLMGLDYPGGPLLSKLAESGTKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRGNEDDLQTRADIAFAFQ
EAVVDTLAIKCRRALKQTGMKRLVMAGGVSANKYLRQELEVMMKKIGGEVYYPRTEFCTDNGAMIAYAGIQRLKNGETTD
LAVQAKPRWPIDQLAPIK
>Mature_338_residues
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIKAALNDAGLTKDDIDGIAYTA
GPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPMLEDEPPAFPFVALLVSGGHTMMVEVKGIGEYQILGESVDD
AAGEAFDKTAKLMGLDYPGGPLLSKLAESGTKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRGNEDDLQTRADIAFAFQ
EAVVDTLAIKCRRALKQTGMKRLVMAGGVSANKYLRQELEVMMKKIGGEVYYPRTEFCTDNGAMIAYAGIQRLKNGETTD
LAVQAKPRWPIDQLAPIK

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=337, Percent_Identity=34.1246290801187, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI8923380, Length=321, Percent_Identity=31.4641744548287, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=79.3413173652695, Blast_Score=558, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI17557464, Length=330, Percent_Identity=30.9090909090909, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71995670, Length=342, Percent_Identity=32.1637426900585, Blast_Score=140, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6320099, Length=370, Percent_Identity=31.6216216216216, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=28.448275862069, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI20129063, Length=338, Percent_Identity=33.1360946745562, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI21357207, Length=327, Percent_Identity=29.6636085626911, Blast_Score=147, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36526; Mature: 36526

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIK
CEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALNDAGLTKDDIDGIAYTAGPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEECCC
LEDEPPAFPFVALLVSGGHTMMVEVKGIGEYQILGESVDDAAGEAFDKTAKLMGLDYPGG
CCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCC
PLLSKLAESGTKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRGNEDDLQTRADIAFAFQ
HHHHHHHHCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
EAVVDTLAIKCRRALKQTGMKRLVMAGGVSANKYLRQELEVMMKKIGGEVYYPRTEFCTD
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEECCCHHEECC
NGAMIAYAGIQRLKNGETTDLAVQAKPRWPIDQLAPIK
CCCEEEHHHHHHHCCCCCCEEEEEECCCCCHHHCCCCC
>Mature Secondary Structure
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIK
CEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALNDAGLTKDDIDGIAYTAGPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEECCC
LEDEPPAFPFVALLVSGGHTMMVEVKGIGEYQILGESVDDAAGEAFDKTAKLMGLDYPGG
CCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCC
PLLSKLAESGTKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRGNEDDLQTRADIAFAFQ
HHHHHHHHCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
EAVVDTLAIKCRRALKQTGMKRLVMAGGVSANKYLRQELEVMMKKIGGEVYYPRTEFCTD
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEECCCHHEECC
NGAMIAYAGIQRLKNGETTDLAVQAKPRWPIDQLAPIK
CCCEEEHHHHHHHCCCCCCEEEEEECCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA