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The map label for this gene is tolC [H]

Identifier: 59712840

GI number: 59712840

Start: 2505031

End: 2506356

Strand: Direct

Name: tolC [H]

Synonym: VF_2233

Alternate gene names: 59712840

Gene position: 2505031-2506356 (Clockwise)

Preceding gene: 59712833

Following gene: 59712844

Centisome position: 86.45

GC content: 40.5

Gene sequence:

>1326_bases
ATGAGAAAACTGCTTCCACTCTTTATTGGAATGGCACTAGGTAGTTTCAGCTCTTTAGCTGCTGCCGATGATCTAGCACA
AGTCTACAACCAAGCTAAAGAAAATGACCCTCAGCTATTAAGAGCTGCTGCAACGAAAGACGCAGCGTTTGAAGCGGTAA
ACTCTTCGCAAAGTTCATTGTTACCTCAAATCGACTTAACAGCAGGCTACAATATTTTACGTAGTGACAACGATACTCGT
GATAATGATCGTTTAACTGCTGGTATTAACCTTTCTCAAGAGCTATACCAACAGTCTAGCTGGGTTAGCTTAGACATTGC
AGAGAAAAGCGCTCGCCAAGCAGACTCGGCATATGCAGCAGAACAACAAGGTGTCATTTTACGTGTCGCACAAGCTTACT
TTGACGTGCTGCGTGCCAACGATAACCTAGAATTTGTACGAGCAGAAAAAGCAGCCGTTGCTCGTCAACTTGAACAAACA
AAACAACGTTTTGATGTAGGTTTGTCAGCAATTACCGATGTTCATGATGCTCAAGCTCAATACGATAGCGTATTAGCAAA
TGAAGTATTAACAGAGAACCAATTAGTAAATAGCTACGAAGATTTACGAGTAATTACAGGCCAGGGCCATACTCACCTAA
GCGTACTTGATACTAAACGCTTTTCAGCAAGCCCATCAGAGCAATCATCTGATAGCCTAATTGAAGAAGCACAAGAGAAA
AACTTGAGTTTATTAGCCGCTCGTATCAGCGCTGATGTAGCAAAAGATAATATTTCTCTAGCAAGTTCTGGTCACATGCC
ATCACTGACATTTGATGCGGGTTATAACTACACGGATCAAAGTGGCACAAAAAATGGCTTTAATGATGATAGCTACGGCG
ACATCAATGCTGGTATTAATTTATATATCCCACTATATACCGGTGGTAATACAAGCTCACTAACAAGCCAAGCTGAATTC
CAATATGTAGCAGCAAGCCAAGAGCTAGAAGCAACGTACCGTGATGTAACTAAAAATGTACGTGCATTTAATAACAACAT
CAATGCGTCAATTGGTGCTTTAAAAGCATACGAACAGACAGTTATCTCTGCACAATCAGCATTAGAAGCGACAGAAGCAG
GTTTTGATGTTGGTACTCGTACTATTGTTGATGTATTAGACTCTACTCGTCGTTTGTATGATGCAAACCGTAACTTAGCA
AACGCTCGTTACGATTACATTATTAGCGTACTTCAGTTAAAACAAGCAGTTGGCACACTAAGCGAACAAGATATCATGGA
TATCAACATGGGTTTAAAAGCAAATAAGACGACACAAACCAAATAA

Upstream 100 bases:

>100_bases
AAAACGTAAAAAAACGTAATCTTTAGAGCCAGAGGGTGTCTAGATAAGGTACACTCTATGAACTATATTATATAAAACAA
TTTTTGCAGGACAAACCACC

Downstream 100 bases:

>100_bases
GTTGATACCAATTATGTAATTACTACATAATTAGCACACAAACAAAAAAGCCACATTACTATAATGTGGCTTTTCTTTTA
TCCGTTGCCGCTATTAGCCG

Product: outer membrane channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MRKLLPLFIGMALGSFSSLAAADDLAQVYNQAKENDPQLLRAAATKDAAFEAVNSSQSSLLPQIDLTAGYNILRSDNDTR
DNDRLTAGINLSQELYQQSSWVSLDIAEKSARQADSAYAAEQQGVILRVAQAYFDVLRANDNLEFVRAEKAAVARQLEQT
KQRFDVGLSAITDVHDAQAQYDSVLANEVLTENQLVNSYEDLRVITGQGHTHLSVLDTKRFSASPSEQSSDSLIEEAQEK
NLSLLAARISADVAKDNISLASSGHMPSLTFDAGYNYTDQSGTKNGFNDDSYGDINAGINLYIPLYTGGNTSSLTSQAEF
QYVAASQELEATYRDVTKNVRAFNNNINASIGALKAYEQTVISAQSALEATEAGFDVGTRTIVDVLDSTRRLYDANRNLA
NARYDYIISVLQLKQAVGTLSEQDIMDINMGLKANKTTQTK

Sequences:

>Translated_441_residues
MRKLLPLFIGMALGSFSSLAAADDLAQVYNQAKENDPQLLRAAATKDAAFEAVNSSQSSLLPQIDLTAGYNILRSDNDTR
DNDRLTAGINLSQELYQQSSWVSLDIAEKSARQADSAYAAEQQGVILRVAQAYFDVLRANDNLEFVRAEKAAVARQLEQT
KQRFDVGLSAITDVHDAQAQYDSVLANEVLTENQLVNSYEDLRVITGQGHTHLSVLDTKRFSASPSEQSSDSLIEEAQEK
NLSLLAARISADVAKDNISLASSGHMPSLTFDAGYNYTDQSGTKNGFNDDSYGDINAGINLYIPLYTGGNTSSLTSQAEF
QYVAASQELEATYRDVTKNVRAFNNNINASIGALKAYEQTVISAQSALEATEAGFDVGTRTIVDVLDSTRRLYDANRNLA
NARYDYIISVLQLKQAVGTLSEQDIMDINMGLKANKTTQTK
>Mature_441_residues
MRKLLPLFIGMALGSFSSLAAADDLAQVYNQAKENDPQLLRAAATKDAAFEAVNSSQSSLLPQIDLTAGYNILRSDNDTR
DNDRLTAGINLSQELYQQSSWVSLDIAEKSARQADSAYAAEQQGVILRVAQAYFDVLRANDNLEFVRAEKAAVARQLEQT
KQRFDVGLSAITDVHDAQAQYDSVLANEVLTENQLVNSYEDLRVITGQGHTHLSVLDTKRFSASPSEQSSDSLIEEAQEK
NLSLLAARISADVAKDNISLASSGHMPSLTFDAGYNYTDQSGTKNGFNDDSYGDINAGINLYIPLYTGGNTSSLTSQAEF
QYVAASQELEATYRDVTKNVRAFNNNINASIGALKAYEQTVISAQSALEATEAGFDVGTRTIVDVLDSTRRLYDANRNLA
NARYDYIISVLQLKQAVGTLSEQDIMDINMGLKANKTTQTK

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=443, Percent_Identity=46.5011286681716, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48100; Mature: 48100

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLLPLFIGMALGSFSSLAAADDLAQVYNQAKENDPQLLRAAATKDAAFEAVNSSQSSL
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHC
LPQIDLTAGYNILRSDNDTRDNDRLTAGINLSQELYQQSSWVSLDIAEKSARQADSAYAA
CCEEECCCCCCEEECCCCCCCCCCEEECCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
EQQGVILRVAQAYFDVLRANDNLEFVRAEKAAVARQLEQTKQRFDVGLSAITDVHDAQAQ
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDSVLANEVLTENQLVNSYEDLRVITGQGHTHLSVLDTKRFSASPSEQSSDSLIEEAQEK
HHHHHHHHHHHHHHHHCCHHCEEEEECCCCEEEEEEECHHCCCCCCCCCHHHHHHHHHHC
NLSLLAARISADVAKDNISLASSGHMPSLTFDAGYNYTDQSGTKNGFNDDSYGDINAGIN
CHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LYIPLYTGGNTSSLTSQAEFQYVAASQELEATYRDVTKNVRAFNNNINASIGALKAYEQT
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VISAQSALEATEAGFDVGTRTIVDVLDSTRRLYDANRNLANARYDYIISVLQLKQAVGTL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
SEQDIMDINMGLKANKTTQTK
CCCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure
MRKLLPLFIGMALGSFSSLAAADDLAQVYNQAKENDPQLLRAAATKDAAFEAVNSSQSSL
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHC
LPQIDLTAGYNILRSDNDTRDNDRLTAGINLSQELYQQSSWVSLDIAEKSARQADSAYAA
CCEEECCCCCCEEECCCCCCCCCCEEECCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
EQQGVILRVAQAYFDVLRANDNLEFVRAEKAAVARQLEQTKQRFDVGLSAITDVHDAQAQ
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDSVLANEVLTENQLVNSYEDLRVITGQGHTHLSVLDTKRFSASPSEQSSDSLIEEAQEK
HHHHHHHHHHHHHHHHCCHHCEEEEECCCCEEEEEEECHHCCCCCCCCCHHHHHHHHHHC
NLSLLAARISADVAKDNISLASSGHMPSLTFDAGYNYTDQSGTKNGFNDDSYGDINAGIN
CHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LYIPLYTGGNTSSLTSQAEFQYVAASQELEATYRDVTKNVRAFNNNINASIGALKAYEQT
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VISAQSALEATEAGFDVGTRTIVDVLDSTRRLYDANRNLANARYDYIISVLQLKQAVGTL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
SEQDIMDINMGLKANKTTQTK
CCCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]