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The map label for this gene is diaA [H]

Identifier: 59712820

GI number: 59712820

Start: 2486998

End: 2487588

Strand: Direct

Name: diaA [H]

Synonym: VF_2213

Alternate gene names: 59712820

Gene position: 2486998-2487588 (Clockwise)

Preceding gene: 59712819

Following gene: 59712821

Centisome position: 85.83

GC content: 41.62

Gene sequence:

>591_bases
ATGCTAGAAAATATCAAAGAAAGCTTTACTGAAAGCATTCAAATCCAAATTGCCGCAGCGGAAGCTCTACCTGACCATAT
CATGCACGCATCCCAAGCGATGGTTGCAACATTATTAAACGGCAATAAAATTCTATGTTGTGGTAACGGTGGTTCTGCAT
CAAATGCACAACAATTTGCCTCTTGCCTATTAAATCGATTTGAGACTGAACGCCCTAGCCTTCCTGCAATGGCTCTTACT
GCTGATACCTCAACGCTGACAGCGATTGCTAATGATTACAATTACTCTGAAATCTTTTCAAAGCAAGTTCGAGCACTAGG
TCAACCAGGCGATATTTTATTAGCAATATCAACGAGTGGAAACAGTCAAGATATCCTAAAAGCAATGGAAGCCGCAGTAA
GTCGTGATATGACGATTATTGCCTTAACGGGCATGGATGGTGGCGTTATGGCTGGTTTACTTGGTGAATCGGATGTAGAA
ATTCGAATACCTTCTCACCGTGTAGCTCGCATTCAAGAAGTTCACCTATTAACATTGCATTGCATTTGTGATCTTGTTGA
TCAGGTTCTTTTCCCACAACACACCGAGTAA

Upstream 100 bases:

>100_bases
CTCTGTTGAACATACATCTTTTAGATTTGATGTCGTTGCTATCCATGCTCAAGGTAAGGAAATCAACTGGATCAAAAATG
CTATTGTTGAAGGGTAAACA

Downstream 100 bases:

>100_bases
TAATATGAAATTAGTGAAATTAAGTGCTTTACTGCTTTCTGCGGTATTACTGCAAGGTTGTGCTGGCTTGTTCATTGCAG
GAGCGGCAACAACCGCGTCT

Product: DnaA initiator-associating factor for replication initiation

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MLENIKESFTESIQIQIAAAEALPDHIMHASQAMVATLLNGNKILCCGNGGSASNAQQFASCLLNRFETERPSLPAMALT
ADTSTLTAIANDYNYSEIFSKQVRALGQPGDILLAISTSGNSQDILKAMEAAVSRDMTIIALTGMDGGVMAGLLGESDVE
IRIPSHRVARIQEVHLLTLHCICDLVDQVLFPQHTE

Sequences:

>Translated_196_residues
MLENIKESFTESIQIQIAAAEALPDHIMHASQAMVATLLNGNKILCCGNGGSASNAQQFASCLLNRFETERPSLPAMALT
ADTSTLTAIANDYNYSEIFSKQVRALGQPGDILLAISTSGNSQDILKAMEAAVSRDMTIIALTGMDGGVMAGLLGESDVE
IRIPSHRVARIQEVHLLTLHCICDLVDQVLFPQHTE
>Mature_196_residues
MLENIKESFTESIQIQIAAAEALPDHIMHASQAMVATLLNGNKILCCGNGGSASNAQQFASCLLNRFETERPSLPAMALT
ADTSTLTAIANDYNYSEIFSKQVRALGQPGDILLAISTSGNSQDILKAMEAAVSRDMTIIALTGMDGGVMAGLLGESDVE
IRIPSHRVARIQEVHLLTLHCICDLVDQVLFPQHTE

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=196, Percent_Identity=68.8775510204082, Blast_Score=284, Evalue=3e-78,
Organism=Escherichia coli, GI1786416, Length=163, Percent_Identity=42.9447852760736, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21025; Mature: 21025

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENIKESFTESIQIQIAAAEALPDHIMHASQAMVATLLNGNKILCCGNGGSASNAQQFA
CCCHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
SCLLNRFETERPSLPAMALTADTSTLTAIANDYNYSEIFSKQVRALGQPGDILLAISTSG
HHHHHHHCCCCCCCCEEEEECCCHHEEEHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCC
NSQDILKAMEAAVSRDMTIIALTGMDGGVMAGLLGESDVEIRIPSHRVARIQEVHLLTLH
CHHHHHHHHHHHHHCCEEEEEEECCCCCCEEHCCCCCCEEEEECCHHHHHHHHHHHHHHH
CICDLVDQVLFPQHTE
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLENIKESFTESIQIQIAAAEALPDHIMHASQAMVATLLNGNKILCCGNGGSASNAQQFA
CCCHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
SCLLNRFETERPSLPAMALTADTSTLTAIANDYNYSEIFSKQVRALGQPGDILLAISTSG
HHHHHHHCCCCCCCCEEEEECCCHHEEEHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCC
NSQDILKAMEAAVSRDMTIIALTGMDGGVMAGLLGESDVEIRIPSHRVARIQEVHLLTLH
CHHHHHHHHHHHHHCCEEEEEEECCCCCCEEHCCCCCCEEEEECCHHHHHHHHHHHHHHH
CICDLVDQVLFPQHTE
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA