Click here to switch to the map view.

The map label for this gene is dksA [H]

Identifier: 59712772

GI number: 59712772

Start: 2435161

End: 2435610

Strand: Direct

Name: dksA [H]

Synonym: VF_2165

Alternate gene names: 59712772

Gene position: 2435161-2435610 (Clockwise)

Preceding gene: 59712771

Following gene: 172087757

Centisome position: 84.04

GC content: 41.33

Gene sequence:

>450_bases
ATGCCAGAGAGCAATACAAAAAGAACGCTAGGAATTCTAGCTATCGCTGGTGTTGAACCTTATCAGGAAAAAGCCGGTGA
GGAATACATGGGCCCAGCCCAAGTTGAACACTTTACAAAGATTCTAGAAGCTTGGCGTAACCAACTTAGGGAAGAAGTTG
CACGCACTGTGAACCACATGAAAGATGAAGCAGCGAACTTTCCAGATCCAGTTGATCGCGCAGCTCAAGAAGAAGAATTT
AGTTTAGAACTGCGTAATCGTGACCGTGAGCGCCGTTTAATTAAGAAAATTGAGAAAACACTAACAAAAATCGAAGAAGA
AGAATTCGGCTTCTGTGATTCTTGTGGTATTGAAATAGGTATTCGTCGATTAGAAGCACGTCCAACTGCTGATCTTTGTA
TTGACTGTAAAACTCTTGCAGAAATCAAAGAAAAGCAAATGGCAGGTTAA

Upstream 100 bases:

>100_bases
CAATTGATGAAATCAATATTTGATTGCCTCTTTTCTTTCTGCTATAGATAGCGCCCTCATTTGGCTAGTGAGAGTCAAAG
ACGTTTTAGGAGAAGCTGTA

Downstream 100 bases:

>100_bases
TACCTATCAAATCATAAAAAAGGGAGCATTCGCTCCCTTTTTTACGTTTAAATAGTGAATATTTATGACAACTCAATACA
TTGGTCGTTTTGCACCATCA

Product: DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MPESNTKRTLGILAIAGVEPYQEKAGEEYMGPAQVEHFTKILEAWRNQLREEVARTVNHMKDEAANFPDPVDRAAQEEEF
SLELRNRDRERRLIKKIEKTLTKIEEEEFGFCDSCGIEIGIRRLEARPTADLCIDCKTLAEIKEKQMAG

Sequences:

>Translated_149_residues
MPESNTKRTLGILAIAGVEPYQEKAGEEYMGPAQVEHFTKILEAWRNQLREEVARTVNHMKDEAANFPDPVDRAAQEEEF
SLELRNRDRERRLIKKIEKTLTKIEEEEFGFCDSCGIEIGIRRLEARPTADLCIDCKTLAEIKEKQMAG
>Mature_148_residues
PESNTKRTLGILAIAGVEPYQEKAGEEYMGPAQVEHFTKILEAWRNQLREEVARTVNHMKDEAANFPDPVDRAAQEEEFS
LELRNRDRERRLIKKIEKTLTKIEEEEFGFCDSCGIEIGIRRLEARPTADLCIDCKTLAEIKEKQMAG

Specific function: Dosage-dependent suppressor of a dnaK deletion mutation. It suppressed not only the temperature-sensitive growth but also the filamentous phenotype of the dnaK deletion strain, while the defect of lambda growth is not suppressed [H]

COG id: COG1734

COG function: function code T; DnaK suppressor protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 dksA C4-type zinc finger [H]

Homologues:

Organism=Escherichia coli, GI1786338, Length=151, Percent_Identity=80.794701986755, Blast_Score=253, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012784
- InterPro:   IPR020460
- InterPro:   IPR000962
- InterPro:   IPR020458 [H]

Pfam domain/function: PF01258 zf-dskA_traR [H]

EC number: NA

Molecular weight: Translated: 17124; Mature: 16992

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS01102 ZF_DKSA_1 ; PS51128 ZF_DKSA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESNTKRTLGILAIAGVEPYQEKAGEEYMGPAQVEHFTKILEAWRNQLREEVARTVNHM
CCCCCCHHHHHHHHCCCCCHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDEAANFPDPVDRAAQEEEFSLELRNRDRERRLIKKIEKTLTKIEEEEFGFCDSCGIEIG
HHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IRRLEARPTADLCIDCKTLAEIKEKQMAG
HHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PESNTKRTLGILAIAGVEPYQEKAGEEYMGPAQVEHFTKILEAWRNQLREEVARTVNHM
CCCCCHHHHHHHHCCCCCHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDEAANFPDPVDRAAQEEEFSLELRNRDRERRLIKKIEKTLTKIEEEEFGFCDSCGIEIG
HHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IRRLEARPTADLCIDCKTLAEIKEKQMAG
HHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]