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The map label for this gene is cdaR [H]

Identifier: 59712762

GI number: 59712762

Start: 2411794

End: 2412939

Strand: Direct

Name: cdaR [H]

Synonym: VF_2155

Alternate gene names: 59712762

Gene position: 2411794-2412939 (Clockwise)

Preceding gene: 59712755

Following gene: 59712763

Centisome position: 83.24

GC content: 35.17

Gene sequence:

>1146_bases
ATGCAGTTAACCACAATGATCGCCAAACAAATTGTTGAGCGTTCAATGAAAATTATCAAACACTCTGTCAATGTGATGGA
TGAGTATGGTGTGATTATTGGTTCAGGGGATCCATCAAGATTAAACTGTCGCCATGAAGGGGCAATACTCGCTATTAATG
AAAATCGAGAAGTTGAAATCGATTACTCTACAGCTCAACAATTACGTGGTGTAAAAGCTGGAATTAACTTACCTATTGTG
TTTCAAAATAAGGTTATTGGGGTTGTTGGTATTTCTGGAAAACCTTCAGAGATCCAACAATACGGTGAGTTAGTAAAAAT
GACTGCCGAACTTATCATTGAGCAAGCCGCTTTAATGACAGAAATCCAGTGGTCTAAACGTCACAAAGAAGAATTAGTTC
TACAATTAATTCAACCATCAGACTTAAATACACAACAGCTTTATTCAATTGCAGAACGATTAGAACTCGATCTTAATCAA
CCACGAATCGCAACCATTATTAAGGTAGATTCTTTTAATGGTGAAAACCTTTCTCTCAGCCATCTTCAAAAATTAGTTCA
TTTATTAGAATATCCAGAGCGCGATAATTTAGTGGCAATCAGCTCCGTGACCTTAAACGAAGTTGTGGTATTAAAGCCAA
TTACATTAACGGATACGGGGTGGAATCGAAGTCATGAAGAAAAAAGGATCCGCCAATTATTTCAACGCATCTCTCATGAT
GAGAAATTCACAATCAAAATAGCATTGGGTGATTACTTTCCAAATCTAGAGGGACTAGCACAATCTTATATGACAGCAAA
AGCGACCATGAGTACTGCTAATGCTAAAAATCGCATTTTATTTTTCCAAGATAACAAACTACCCGTTTTAATTAATGGAA
TAAAATCCGATACTTGGCGCATGGAACAATTAAAGCAACCTATCGTTAATCTTCAAAAATCAGATCCTAAAGGGATATTA
CTCAAAACCCTTAAAGCCTTTTTTAATCATAATTGTGATTCAGCTCAAACCTGTAAATCATTACATATTCATCGGAATAC
TCTTCGCTACAGGCTGGATAAAATAAACAAAGAAACAAGCTTAGATATCAATAAGATAAATGATTCTACCTATTTGTACC
TTGCTTCATTAATGAGCAATAAATAA

Upstream 100 bases:

>100_bases
GGATCAAAGACAATGCCGAGCTCTTTTACTCCAGTATAATCTTATCCCTATTTTTTTTATAGCTAACTCCCTCCTTTCTT
AATAGCTAAAAGGTTTAAAG

Downstream 100 bases:

>100_bases
TACTCAATTTGTGCAATTGCACAATGATTTAAATATTTAATCGATAAAATTTGGGCATTCGACTAAAGCATATTGATAAC
GATAACGTTAGATTACCGAC

Product: DNA-binding transcriptional activator

Products: NA

Alternate protein names: Sugar diacid regulator [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MQLTTMIAKQIVERSMKIIKHSVNVMDEYGVIIGSGDPSRLNCRHEGAILAINENREVEIDYSTAQQLRGVKAGINLPIV
FQNKVIGVVGISGKPSEIQQYGELVKMTAELIIEQAALMTEIQWSKRHKEELVLQLIQPSDLNTQQLYSIAERLELDLNQ
PRIATIIKVDSFNGENLSLSHLQKLVHLLEYPERDNLVAISSVTLNEVVVLKPITLTDTGWNRSHEEKRIRQLFQRISHD
EKFTIKIALGDYFPNLEGLAQSYMTAKATMSTANAKNRILFFQDNKLPVLINGIKSDTWRMEQLKQPIVNLQKSDPKGIL
LKTLKAFFNHNCDSAQTCKSLHIHRNTLRYRLDKINKETSLDINKINDSTYLYLASLMSNK

Sequences:

>Translated_381_residues
MQLTTMIAKQIVERSMKIIKHSVNVMDEYGVIIGSGDPSRLNCRHEGAILAINENREVEIDYSTAQQLRGVKAGINLPIV
FQNKVIGVVGISGKPSEIQQYGELVKMTAELIIEQAALMTEIQWSKRHKEELVLQLIQPSDLNTQQLYSIAERLELDLNQ
PRIATIIKVDSFNGENLSLSHLQKLVHLLEYPERDNLVAISSVTLNEVVVLKPITLTDTGWNRSHEEKRIRQLFQRISHD
EKFTIKIALGDYFPNLEGLAQSYMTAKATMSTANAKNRILFFQDNKLPVLINGIKSDTWRMEQLKQPIVNLQKSDPKGIL
LKTLKAFFNHNCDSAQTCKSLHIHRNTLRYRLDKINKETSLDINKINDSTYLYLASLMSNK
>Mature_381_residues
MQLTTMIAKQIVERSMKIIKHSVNVMDEYGVIIGSGDPSRLNCRHEGAILAINENREVEIDYSTAQQLRGVKAGINLPIV
FQNKVIGVVGISGKPSEIQQYGELVKMTAELIIEQAALMTEIQWSKRHKEELVLQLIQPSDLNTQQLYSIAERLELDLNQ
PRIATIIKVDSFNGENLSLSHLQKLVHLLEYPERDNLVAISSVTLNEVVVLKPITLTDTGWNRSHEEKRIRQLFQRISHD
EKFTIKIALGDYFPNLEGLAQSYMTAKATMSTANAKNRILFFQDNKLPVLINGIKSDTWRMEQLKQPIVNLQKSDPKGIL
LKTLKAFFNHNCDSAQTCKSLHIHRNTLRYRLDKINKETSLDINKINDSTYLYLASLMSNK

Specific function: Seems to regulate the expression of the operons for the enzymes involved in D-galactarate, D-glucarate and D-glycerate utilization [H]

COG id: COG3835

COG function: function code KT; Sugar diacid utilization regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdaR family [H]

Homologues:

Organism=Escherichia coli, GI87081694, Length=378, Percent_Identity=42.8571428571429, Blast_Score=310, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008599 [H]

Pfam domain/function: PF05651 Diacid_rec [H]

EC number: NA

Molecular weight: Translated: 43391; Mature: 43391

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTTMIAKQIVERSMKIIKHSVNVMDEYGVIIGSGDPSRLNCRHEGAILAINENREVEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEECCCCEEEE
DYSTAQQLRGVKAGINLPIVFQNKVIGVVGISGKPSEIQQYGELVKMTAELIIEQAALMT
EHHHHHHHCHHHCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQWSKRHKEELVLQLIQPSDLNTQQLYSIAERLELDLNQPRIATIIKVDSFNGENLSLS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHH
HLQKLVHLLEYPERDNLVAISSVTLNEVVVLKPITLTDTGWNRSHEEKRIRQLFQRISHD
HHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC
EKFTIKIALGDYFPNLEGLAQSYMTAKATMSTANAKNRILFFQDNKLPVLINGIKSDTWR
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCHHH
MEQLKQPIVNLQKSDPKGILLKTLKAFFNHNCDSAQTCKSLHIHRNTLRYRLDKINKETS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
LDINKINDSTYLYLASLMSNK
CEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MQLTTMIAKQIVERSMKIIKHSVNVMDEYGVIIGSGDPSRLNCRHEGAILAINENREVEI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEECCCCEEEE
DYSTAQQLRGVKAGINLPIVFQNKVIGVVGISGKPSEIQQYGELVKMTAELIIEQAALMT
EHHHHHHHCHHHCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQWSKRHKEELVLQLIQPSDLNTQQLYSIAERLELDLNQPRIATIIKVDSFNGENLSLS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCHH
HLQKLVHLLEYPERDNLVAISSVTLNEVVVLKPITLTDTGWNRSHEEKRIRQLFQRISHD
HHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCC
EKFTIKIALGDYFPNLEGLAQSYMTAKATMSTANAKNRILFFQDNKLPVLINGIKSDTWR
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCHHH
MEQLKQPIVNLQKSDPKGILLKTLKAFFNHNCDSAQTCKSLHIHRNTLRYRLDKINKETS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
LDINKINDSTYLYLASLMSNK
CEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10762278 [H]