Click here to switch to the map view.

The map label for this gene is gntP [C]

Identifier: 59712763

GI number: 59712763

Start: 2413067

End: 2414332

Strand: Direct

Name: gntP [C]

Synonym: VF_2156

Alternate gene names: 59712763

Gene position: 2413067-2414332 (Clockwise)

Preceding gene: 59712762

Following gene: 59712764

Centisome position: 83.28

GC content: 44.31

Gene sequence:

>1266_bases
ATGATCGAAGTATCTACCCTAGGCGCTATTTCAGCGCTCGTTGTTGCTATCACCCTCATCCTTAAAAAGGTCCCGCCTGC
TTATGGCATGATTATTGGTGCTCTAATTGGTGGTATTGTCGGTGGCGTTTCATTAACAGATACAGTTAACTTGATGATTG
GCGGTGCTCAAGGAATTGTTACCGCTGTTTTACGAATTCTTGCAGCTGGTGTTCTTGCTGGTGTATTAATTGAATCAGGT
GCGGCAACCTCTATTGCAGAAACCATAGTAAAAAAAGTAGGCGAAACCAGAGCACTGTTAGCATTAGCAGTTGCAACTAT
GATCTTAACGGCTGTGGGTGTTTTCGTAGACGTTGCTGTAATTACTGTTGCACCTATTGCACTTGCGATTGCTCAGCGTG
CAGACCTATCTAAAATGGCTATCTTATTAGCGATGGTTGGCGGCGGTAAAGCTGGTAACGTAATGTCACCTAACCCAAAT
GCGATTGCGGCAGCCGATGCTTTTAATGTGCCTTTAACTTCAGTGATGGCAGCTGGTGTTATCCCTGGATTATTTGGGTT
AGTCTTTGCTTATTTCATCGCTAAAAAACTTGTTAATAAAGGCAGCAAAGTCCAAGCTCATGAAGTAGTTTCTGTTGATC
ATTCTCGCCTACCTAGTTTTACGACTTCAATCGTAGCTCCCCTTGTTGCAATCAGCCTTTTAGCCCTGCGCCCAATAGCA
GGTATTAATGTCGATCCTCTCATTGCACTTCCTTTGGGTGGCCTACTGGGTGCTGTAGCAATGAGACGCTTTAGAGATAC
CAATCATTTTGCAGTCTCTGGTTTAACTCGTATGGCTCCTGTTGCTGTAATGCTACTTGGTACCGGTACATTAGCAGGTA
TCATTGCAAACTCAGGGTTGAAATCAGGCCTTATAGATATCTTAACGGCTTCAGGCCTTCCATCTTATCTACTTGCTCCG
ATTTCTGGTGCCATGATGTCGTTAGCAACAGCATCAACAACCGCAGGAACTGCCGTTGCAGCAAGTGTATTTAGTCACAC
AATTCTAGAACTTGGCGTTCCTGCTCTTGCTGGTGCTGCAATGATTCACGCTGGTGCAACCGTATTAGATCACATGCCAC
ACGGTAGTTTCTTCCATGCAACTGGTGGCGCTGTACATATGGATATTAAAGAGCGTTTAAAACTTATTCCATACGAATCA
GCGGTTGGTCTAATGATCGCAACTGTTTCAACCCTCATCTTTGGCGTCTTCGGTTTATTTGTTTAA

Upstream 100 bases:

>100_bases
TTTAAATATTTAATCGATAAAATTTGGGCATTCGACTAAAGCATATTGATAACGATAACGTTAGATTACCGACATCTTAA
TTATTAAATGGAACGTTAAT

Downstream 100 bases:

>100_bases
TAAGGCTATATTATGAAAATCGTTATTGCTCCTGACTCTTACAAAGAAAGTTTAACGGCGATGGAAGTCGCTACGGCCAT
TGAAGCTGGATTTAAACAAG

Product: fructuronate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MIEVSTLGAISALVVAITLILKKVPPAYGMIIGALIGGIVGGVSLTDTVNLMIGGAQGIVTAVLRILAAGVLAGVLIESG
AATSIAETIVKKVGETRALLALAVATMILTAVGVFVDVAVITVAPIALAIAQRADLSKMAILLAMVGGGKAGNVMSPNPN
AIAAADAFNVPLTSVMAAGVIPGLFGLVFAYFIAKKLVNKGSKVQAHEVVSVDHSRLPSFTTSIVAPLVAISLLALRPIA
GINVDPLIALPLGGLLGAVAMRRFRDTNHFAVSGLTRMAPVAVMLLGTGTLAGIIANSGLKSGLIDILTASGLPSYLLAP
ISGAMMSLATASTTAGTAVAASVFSHTILELGVPALAGAAMIHAGATVLDHMPHGSFFHATGGAVHMDIKERLKLIPYES
AVGLMIATVSTLIFGVFGLFV

Sequences:

>Translated_421_residues
MIEVSTLGAISALVVAITLILKKVPPAYGMIIGALIGGIVGGVSLTDTVNLMIGGAQGIVTAVLRILAAGVLAGVLIESG
AATSIAETIVKKVGETRALLALAVATMILTAVGVFVDVAVITVAPIALAIAQRADLSKMAILLAMVGGGKAGNVMSPNPN
AIAAADAFNVPLTSVMAAGVIPGLFGLVFAYFIAKKLVNKGSKVQAHEVVSVDHSRLPSFTTSIVAPLVAISLLALRPIA
GINVDPLIALPLGGLLGAVAMRRFRDTNHFAVSGLTRMAPVAVMLLGTGTLAGIIANSGLKSGLIDILTASGLPSYLLAP
ISGAMMSLATASTTAGTAVAASVFSHTILELGVPALAGAAMIHAGATVLDHMPHGSFFHATGGAVHMDIKERLKLIPYES
AVGLMIATVSTLIFGVFGLFV
>Mature_421_residues
MIEVSTLGAISALVVAITLILKKVPPAYGMIIGALIGGIVGGVSLTDTVNLMIGGAQGIVTAVLRILAAGVLAGVLIESG
AATSIAETIVKKVGETRALLALAVATMILTAVGVFVDVAVITVAPIALAIAQRADLSKMAILLAMVGGGKAGNVMSPNPN
AIAAADAFNVPLTSVMAAGVIPGLFGLVFAYFIAKKLVNKGSKVQAHEVVSVDHSRLPSFTTSIVAPLVAISLLALRPIA
GINVDPLIALPLGGLLGAVAMRRFRDTNHFAVSGLTRMAPVAVMLLGTGTLAGIIANSGLKSGLIDILTASGLPSYLLAP
ISGAMMSLATASTTAGTAVAASVFSHTILELGVPALAGAAMIHAGATVLDHMPHGSFFHATGGAVHMDIKERLKLIPYES
AVGLMIATVSTLIFGVFGLFV

Specific function: High-Affinity Gluconate Transporter With Fairly Broad Specificity, Including Low Affinity For Glucuronate, Several Disaccharides, And Some Hexoses, But Not Glucose. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Escherichia coli, GI1788707, Length=251, Percent_Identity=25.8964143426295, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790776, Length=430, Percent_Identity=25.5813953488372, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 42307; Mature: 42307

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVSTLGAISALVVAITLILKKVPPAYGMIIGALIGGIVGGVSLTDTVNLMIGGAQGIV
CEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHEECCHHHHH
TAVLRILAAGVLAGVLIESGAATSIAETIVKKVGETRALLALAVATMILTAVGVFVDVAV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ITVAPIALAIAQRADLSKMAILLAMVGGGKAGNVMSPNPNAIAAADAFNVPLTSVMAAGV
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHH
IPGLFGLVFAYFIAKKLVNKGSKVQAHEVVSVDHSRLPSFTTSIVAPLVAISLLALRPIA
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCCCC
GINVDPLIALPLGGLLGAVAMRRFRDTNHFAVSGLTRMAPVAVMLLGTGTLAGIIANSGL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCH
KSGLIDILTASGLPSYLLAPISGAMMSLATASTTAGTAVAASVFSHTILELGVPALAGAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
MIHAGATVLDHMPHGSFFHATGGAVHMDIKERLKLIPYESAVGLMIATVSTLIFGVFGLF
HHHHCHHHHHCCCCCCEEECCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
V
C
>Mature Secondary Structure
MIEVSTLGAISALVVAITLILKKVPPAYGMIIGALIGGIVGGVSLTDTVNLMIGGAQGIV
CEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHEECCHHHHH
TAVLRILAAGVLAGVLIESGAATSIAETIVKKVGETRALLALAVATMILTAVGVFVDVAV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ITVAPIALAIAQRADLSKMAILLAMVGGGKAGNVMSPNPNAIAAADAFNVPLTSVMAAGV
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHH
IPGLFGLVFAYFIAKKLVNKGSKVQAHEVVSVDHSRLPSFTTSIVAPLVAISLLALRPIA
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCCCC
GINVDPLIALPLGGLLGAVAMRRFRDTNHFAVSGLTRMAPVAVMLLGTGTLAGIIANSGL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCH
KSGLIDILTASGLPSYLLAPISGAMMSLATASTTAGTAVAASVFSHTILELGVPALAGAA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHH
MIHAGATVLDHMPHGSFFHATGGAVHMDIKERLKLIPYESAVGLMIATVSTLIFGVFGLF
HHHHCHHHHHCCCCCCEEECCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]