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The map label for this gene is glmM [H]

Identifier: 59712755

GI number: 59712755

Start: 2404123

End: 2405535

Strand: Direct

Name: glmM [H]

Synonym: VF_2148

Alternate gene names: 59712755

Gene position: 2404123-2405535 (Clockwise)

Preceding gene: 59712754

Following gene: 59712762

Centisome position: 82.97

GC content: 38.43

Gene sequence:

>1413_bases
ATGATTCAATTTGGTACAGGTGGTTGGCGCGCATTTATTGGTGAAGAATTTACCAAAGATAACGTACGTCTTGTTGCTCA
AGCACTATCAAATATTATGATTAACGAACAAGTCCAAAATAAAGGGTTTGTTATTGGTTATGACCGTCGTTTCTTATCAG
ATAAAGCAGGAAAATGGTTTGCAGAAGTGGTTGCAGCCAATGGCATTAAAGTAAGTTTTATTGATAAGTTTGTTCCAACC
CCTATCGTTATGTTCCAAACAAAAGAGATGGGGTGTATCTACTCAGCTTGTATCACTGCATCTCATAACCCTGCAGACTA
CAACGGTGTGAAAGTGTTCATCGAAGGTGGTCGTGACGCCGATGAAATCATTACCCAAAAAATCGAACAACAAATTGCTC
ATTTAACTCAACAAGATGTTAATGCATTAGAATTTGAAGAAGCGGTTACTGCGGGAAAAATTGAAATCATTAACCCAATG
AACGCATTTGTTGACTCAATCATCGACTTTATCGATATCGAATCAATTAAAAAAGCCAACTTACGTGTACTTATCGACCC
AATGTTTGGTGTAGCAAAAAATGCGCTTCAAACGGTTTTAATTAATGGTCGTTGTGATGTTGACGTTATCAACGATGGTG
AAAACCCTGCATTTGGAGGCTTAATGCCATCGCCAAGTGCCGCTACTTTGTATCGCTTAAAACACTTAGTTGCACACGAA
GGTTATGACATTGGTATTGGTACTGATGGAGATGCTGACCGTCTAGGTATTATCGATGAAAAAGGTAATTTTATTCACCC
TAATGAAGTCCTAATTCTCCTTTACTACTACTTACTTGAGTACAAAGGCTGGAAAGGCTCAGTGGTTCGTAATATTGCAA
CGACTCACTTGCTTGATAAAGTCGCAGCAGATCACGGCGAAAAATGCTTTGAGGTACCTGTAGGCTTTAAGCACATCAGC
TCCCAAATGGAAGCCGATGATTCTTTAATCGGTGGGGAAAGTTCAGGTGGTTTAACCATTCGTGGACACATTAAAGGTAA
AGATGGCGTATTCGCTTCTAGCTTATTAGTTGAAATGATCAGCGTGACAGGTAAAAAACTATCTGAAATGCTTGATGAGA
TTTACGCTAAATATGGTTACGCCTATACAGCGGAAGGCGATTGCACCTTTAAACCAGCAGAAAAAGAAACACTGTATAAT
AAAATTTATGTAGAGAAGCAACTGCCTGAATTTGAATATGAAATAGAAAAAGTAAGCTATGAAGATGGTGCAAAAGTTTA
CTTTAAAAATGGCGGTTGGGTCATTGCTCGTTTCTCTGGTACCGAACCATTATTACGTATTTTTGCTGAAATGGAAGACA
AACCAACTGCAGAAAAAGTACTTAATGAAATGAAAGCTTTCCTTTCTCTTTAG

Upstream 100 bases:

>100_bases
TTGTCGTAATTATGGGCTAAGCTCGTTTAATGATGAGCTAAGTGTTATAGACAAAAGTAAGGCACCTTATTCTGGTGCCT
TACTATAAAAGGAATTTACT

Downstream 100 bases:

>100_bases
TTTCTACGTTTTAACTAAAACAAGAGCTCTAAAGAATTAACCCAGCTAATATAAGAGTCTGTTAGCTGGGTTCTTTTTAC
ACTATTAATCCTGAACAAAA

Product: phosphoglucomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MIQFGTGGWRAFIGEEFTKDNVRLVAQALSNIMINEQVQNKGFVIGYDRRFLSDKAGKWFAEVVAANGIKVSFIDKFVPT
PIVMFQTKEMGCIYSACITASHNPADYNGVKVFIEGGRDADEIITQKIEQQIAHLTQQDVNALEFEEAVTAGKIEIINPM
NAFVDSIIDFIDIESIKKANLRVLIDPMFGVAKNALQTVLINGRCDVDVINDGENPAFGGLMPSPSAATLYRLKHLVAHE
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDKVAADHGEKCFEVPVGFKHIS
SQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSEMLDEIYAKYGYAYTAEGDCTFKPAEKETLYN
KIYVEKQLPEFEYEIEKVSYEDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKPTAEKVLNEMKAFLSL

Sequences:

>Translated_470_residues
MIQFGTGGWRAFIGEEFTKDNVRLVAQALSNIMINEQVQNKGFVIGYDRRFLSDKAGKWFAEVVAANGIKVSFIDKFVPT
PIVMFQTKEMGCIYSACITASHNPADYNGVKVFIEGGRDADEIITQKIEQQIAHLTQQDVNALEFEEAVTAGKIEIINPM
NAFVDSIIDFIDIESIKKANLRVLIDPMFGVAKNALQTVLINGRCDVDVINDGENPAFGGLMPSPSAATLYRLKHLVAHE
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDKVAADHGEKCFEVPVGFKHIS
SQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSEMLDEIYAKYGYAYTAEGDCTFKPAEKETLYN
KIYVEKQLPEFEYEIEKVSYEDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKPTAEKVLNEMKAFLSL
>Mature_470_residues
MIQFGTGGWRAFIGEEFTKDNVRLVAQALSNIMINEQVQNKGFVIGYDRRFLSDKAGKWFAEVVAANGIKVSFIDKFVPT
PIVMFQTKEMGCIYSACITASHNPADYNGVKVFIEGGRDADEIITQKIEQQIAHLTQQDVNALEFEEAVTAGKIEIINPM
NAFVDSIIDFIDIESIKKANLRVLIDPMFGVAKNALQTVLINGRCDVDVINDGENPAFGGLMPSPSAATLYRLKHLVAHE
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDKVAADHGEKCFEVPVGFKHIS
SQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMISVTGKKLSEMLDEIYAKYGYAYTAEGDCTFKPAEKETLYN
KIYVEKQLPEFEYEIEKVSYEDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKPTAEKVLNEMKAFLSL

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=468, Percent_Identity=25.6410256410256, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI290463102, Length=456, Percent_Identity=25.4385964912281, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI133922562, Length=533, Percent_Identity=24.015009380863, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI290463104, Length=308, Percent_Identity=25.3246753246753, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786904, Length=485, Percent_Identity=25.979381443299, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1788361, Length=473, Percent_Identity=25.369978858351, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789566, Length=487, Percent_Identity=22.7926078028747, Blast_Score=89, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17535441, Length=499, Percent_Identity=26.8537074148297, Blast_Score=125, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6323752, Length=530, Percent_Identity=27.7358490566038, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6322722, Length=427, Percent_Identity=26.463700234192, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323934, Length=430, Percent_Identity=23.7209302325581, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17864244, Length=527, Percent_Identity=26.7552182163188, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI20129809, Length=544, Percent_Identity=25.1838235294118, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24651977, Length=425, Percent_Identity=25.6470588235294, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24653722, Length=420, Percent_Identity=24.5238095238095, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 52134; Mature: 52134

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQFGTGGWRAFIGEEFTKDNVRLVAQALSNIMINEQVQNKGFVIGYDRRFLSDKAGKWF
CCEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHCCHHHHHH
AEVVAANGIKVSFIDKFVPTPIVMFQTKEMGCIYSACITASHNPADYNGVKVFIEGGRDA
HHHHHCCCCEEEEEHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCH
DEIITQKIEQQIAHLTQQDVNALEFEEAVTAGKIEIINPMNAFVDSIIDFIDIESIKKAN
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCC
LRVLIDPMFGVAKNALQTVLINGRCDVDVINDGENPAFGGLMPSPSAATLYRLKHLVAHE
CEEEECCHHHHHHHHHHEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDK
CEEEECCCCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAADHGEKCFEVPVGFKHISSQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMI
HHHHCCCCEEECCCCHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHH
SVTGKKLSEMLDEIYAKYGYAYTAEGDCTFKPAEKETLYNKIYVEKQLPEFEYEIEKVSY
HHHHHHHHHHHHHHHHHHCCEEECCCCCEECCCHHHHHHHHEEEECCCCCHHHHHHEECC
EDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKPTAEKVLNEMKAFLSL
CCCCEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIQFGTGGWRAFIGEEFTKDNVRLVAQALSNIMINEQVQNKGFVIGYDRRFLSDKAGKWF
CCEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHCCHHHHHH
AEVVAANGIKVSFIDKFVPTPIVMFQTKEMGCIYSACITASHNPADYNGVKVFIEGGRDA
HHHHHCCCCEEEEEHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCH
DEIITQKIEQQIAHLTQQDVNALEFEEAVTAGKIEIINPMNAFVDSIIDFIDIESIKKAN
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCC
LRVLIDPMFGVAKNALQTVLINGRCDVDVINDGENPAFGGLMPSPSAATLYRLKHLVAHE
CEEEECCHHHHHHHHHHEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GYDIGIGTDGDADRLGIIDEKGNFIHPNEVLILLYYYLLEYKGWKGSVVRNIATTHLLDK
CEEEECCCCCCCCCEEEEECCCCEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAADHGEKCFEVPVGFKHISSQMEADDSLIGGESSGGLTIRGHIKGKDGVFASSLLVEMI
HHHHCCCCEEECCCCHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHH
SVTGKKLSEMLDEIYAKYGYAYTAEGDCTFKPAEKETLYNKIYVEKQLPEFEYEIEKVSY
HHHHHHHHHHHHHHHHHHCCEEECCCCCEECCCHHHHHHHHEEEECCCCCHHHHHHEECC
EDGAKVYFKNGGWVIARFSGTEPLLRIFAEMEDKPTAEKVLNEMKAFLSL
CCCCEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]