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The map label for this gene is chiS [H]

Identifier: 59712745

GI number: 59712745

Start: 2387189

End: 2390569

Strand: Direct

Name: chiS [H]

Synonym: VF_2138

Alternate gene names: 59712745

Gene position: 2387189-2390569 (Clockwise)

Preceding gene: 59712744

Following gene: 59712746

Centisome position: 82.39

GC content: 37.41

Gene sequence:

>3381_bases
ATGGATAAAAAACAACACTTTAAACGTCTACAAAATACGTTGATGATTGCGTTTCTTGTTTTAAGCATAACGCCACTATC
ACTTATTGCAATTTTCTTTCTTCACTCTCATAGCCAAGATCTTGCAACGCAAAGTACCGCACATCTTGTGTCATTACGAG
ACAACAAAGAACAACAAATTACAAACTACTTTAAAGGCCGTAAATCCGAAGTATTAGGGTTTGCTCGCTCTGAACTAGCT
AATGCAAGTGGCGGTCGATTTTACGGTTTGGTTAGTGCCTTTCCACACTTAGGAACCTCCATAGAAGACGCTCGTAAAAA
CGCACAACTACGGTATATTACCGGTTCTGGTGATAAAATTAGAACCAGTGTTCTTCCTGAATCAGACTCTTATATTGGTA
GTGAACGCTACCGTCTTCTACATAAACGTTACCATTGGGCATATTTAGAACTCTTAAAACGTTCAGACTTTAGTGACGTT
CTATTAGTTGATATTAATGGCAACGTTGTGTATTCCAAAGCCAAAGAAGACAATTATGGTACGAATTTATTAACAGGTAA
GTACAAAGACAGTACGTTAGCGGATACATATAAAAAGATCCGAACATTAATGAAAAAGCCTGAGAGCGAAGATAATATTC
CTATCATTTTTTCTGATTTCAATACCATAAATAACGAAACGGTAGCATGGTTTGCAGCTCCAATAGTACAGCAAGGTTAT
TTACATAGCTTTGCTCTATTCAAATTACCAAATACAGGTCTAATTGAATTGATTGGAGATAATACTGATACAAGTTCCAT
CAAAACCTACTTTGTAGGCCAAGACTCTTACTCCCGTATCAGCAATGAAGACATTGAAAAAAACCTCTCTGAAAATATGA
AGTTGGCACTATCAGGTGAATCAAATGTCGGTAGCTTTATTGATAAGCACGGAGAAAAAGTGCTTGCTGCATTTACTTCT
ATTAATGTTGATGGGCATTTATGGGGACTATCACTTGAACTTCCAGAAAAAGAAGCTTTTGCTCGCATTCAACAACTTGA
GCAAATCTTTGTTATTGCAATGATAATAGCCATTGTCTGTGTTGTTATTGCTTCGCATTTCTTATCTAACTCAATCACAG
CACCACTTTTACGCTTAACATGGGCGGCAGAACGAGTGTCTGCTGGTGATCTTGATCAAGAGATGATCAGCACGGATAGA
AAAGATGAAATTGGTCGCTTAGCGGTTAGTTTTGCACGAATGCAACGCTCAATAAGAGAAAAAATTCAACTAATTAAAGA
CCAAAATGAAGAGCTTGAAGCTAACTTAGCCACCATTCAATTAAAGAACAATGAACTGGAAGCTGCTGATAAGTTAAAAG
ATGAATTTTTAGCAACCACATCGCATGAGTTAAGAACACCATTACATGGAATGGTTGGCATTGCAGAAGCCTTATACACT
GGAGCTAACGGTCCAATATCAGCATCTCATCGCCATCAATTAGAGATCATTATAAATAGCGGTCAACGCTTAACAAGCCT
GGTTAATGACCTACTTGATTATCATAAAATGCGTCATGGTAACCTTGATATAAATAAACATGTTACCGATTTATCCTCTG
CAACCAGTTTAGTTCTGGAGTTATCGCAACACCTTCTTGGAAACAAATCCATCCGTATTATTAACCAAGTAGATAAATCA
TTACCTGTTGTTTTTGTCGATGAACAACGCCTTGAACAGGTTCTTTATAATCTTATTGGCAATGCGATTAAATATACATC
AGAAGGTAAAATTGTTATCTCAGCAAGTGTTGTAGATCAATTCTTGCGAGTTCAGGTCGTAGACACTGGGCACGGAATTC
CGGCTGATGAATTAGAACATATTTTTGAACCATTAATTCAAGCTGGTCATGATTCAAACCGCTATCGTCAAGGCTCTGGT
CTTGGTCTATCAATCAGTCGACAATTAATTGAATTAATGGGCGGTTCTTTATATGTGAGTAGCCAACCAATGGTAGGAGC
GACATTTAGCTTTACCCTTCCTCTTGCAACTAAAGAACAAATTCAACAACACAAATTGCTTGCTCAAGAAGGTATTACTC
ACTATCAAACGCCTGAAAAACTTGAATATAATTTAGATGAGATTGATGAGGAATTACCAGAAAACCCTGAGGGCCCACTT
TTATTAGTTGCGGATGATGAACCCGTCAATCTACAAGTACTTACTAGTTTCTTAAAACTCGAAGGGTACCGAGTGAAAGT
GGCTAATGATGGACCTGAAACATTAAAAGTATTTGAAGAAGAAAAGCCTGAATTATTATTGCTTGATGTCATGATGCCAG
GAATGAGCGGCTATGAAGTATGCCAATCATTAAGAGAGACTTATAGCCACTCTGAACTACCTATTATTATGTTAACAGCC
TTAAATCAAACTCAAGATAGAATTCGAGGTTTTGAGTCAGGCGCTAACGACTATTTAAGTAAGCCTTTTAATAAACAAGA
ACTAGCAGCTCGAATAAAAGCGCACCTTAAAGCAAGTAAGGCTGAATTATTCTTAAGTGAAAATGACCGTCTACAGCAGG
AAATTCGCCATAGAGAAAAAGTAGAAGCCAGTTTACTTGAGACACAGGCTCATATATTAGAGCAACTTAATCATGCACAA
GAAGCCATTATATGCGCAAAAAGTGATGGAAAAATTAAGTATGTAAATAACTCTGCTGCAAAACTATTTCAAAGAACAGA
AGAACAACTTTCACGTTATTCTATTGATGAGCTAATAGCTAAACGTAGCCTTATTGAAAGTAAACAAAACCACCGTGGCA
ATATTGATGTTTATATTGATGGTGAAATAACACAAATAAACGCTGATTTATTACATCTTCCTGCAGAGTCCGGGCTATCC
CTTATTCTTGTAGTTAGCCATAAACACGAAGCAAACGAACAACGAATTCATGACTTAGAAAGTGCAGTAGAAGCACTATC
TGCATTTGCATTCGAAGGCGATAAACAAAAGCTAAACTCGCTATCACTAGTTGGTGGGGATATTGCTCAACTAGCCACTA
AAGCCAATGAAAATAAAGAAGACAAAGGCACTATCATGCGAGAACTCATTGTTGACGGCATGATCTCAGGCCTTTCTTAT
TGGGAAGAGTCTACAGGGCAAACCAAATACACTCTCGCAGAAGAGAGTGGGTTATGGCGAGTGTATTTAGATAGAAGCAC
ACTACAAACACGTACACTTGATAAATACTTACGAGTAGAAACTCTGCCAAAAACACCACGCTGGAGAACCGTAATTAGTA
CGTTAGAGTACATTTTAGAACATTGTGAGCAATACAATGACCAACGTGACAAACTGGTTAGAATTAAAGATAAACTACAA
ATACTCATATCCAACAACTAA

Upstream 100 bases:

>100_bases
GCAGCAGAGTTTCTCGTTAAAATCAAACTCAATAAAATTTACTGACACGTTAAATATGTCAATTTCGCTGAATGGATAAC
AGTGTGGACTAGGCCTTCAA

Downstream 100 bases:

>100_bases
TTTTACCATCGTAACTCAAACTAAAAGCCCGTATATTTACGGGCTTTTTTTTCACCACTACCAAATTCACGGTTCAAAAA
AAGCACTTAATCAGCACAGT

Product: chitin sensor histidine kinase ChiS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1126; Mature: 1126

Protein sequence:

>1126_residues
MDKKQHFKRLQNTLMIAFLVLSITPLSLIAIFFLHSHSQDLATQSTAHLVSLRDNKEQQITNYFKGRKSEVLGFARSELA
NASGGRFYGLVSAFPHLGTSIEDARKNAQLRYITGSGDKIRTSVLPESDSYIGSERYRLLHKRYHWAYLELLKRSDFSDV
LLVDINGNVVYSKAKEDNYGTNLLTGKYKDSTLADTYKKIRTLMKKPESEDNIPIIFSDFNTINNETVAWFAAPIVQQGY
LHSFALFKLPNTGLIELIGDNTDTSSIKTYFVGQDSYSRISNEDIEKNLSENMKLALSGESNVGSFIDKHGEKVLAAFTS
INVDGHLWGLSLELPEKEAFARIQQLEQIFVIAMIIAIVCVVIASHFLSNSITAPLLRLTWAAERVSAGDLDQEMISTDR
KDEIGRLAVSFARMQRSIREKIQLIKDQNEELEANLATIQLKNNELEAADKLKDEFLATTSHELRTPLHGMVGIAEALYT
GANGPISASHRHQLEIIINSGQRLTSLVNDLLDYHKMRHGNLDINKHVTDLSSATSLVLELSQHLLGNKSIRIINQVDKS
LPVVFVDEQRLEQVLYNLIGNAIKYTSEGKIVISASVVDQFLRVQVVDTGHGIPADELEHIFEPLIQAGHDSNRYRQGSG
LGLSISRQLIELMGGSLYVSSQPMVGATFSFTLPLATKEQIQQHKLLAQEGITHYQTPEKLEYNLDEIDEELPENPEGPL
LLVADDEPVNLQVLTSFLKLEGYRVKVANDGPETLKVFEEEKPELLLLDVMMPGMSGYEVCQSLRETYSHSELPIIMLTA
LNQTQDRIRGFESGANDYLSKPFNKQELAARIKAHLKASKAELFLSENDRLQQEIRHREKVEASLLETQAHILEQLNHAQ
EAIICAKSDGKIKYVNNSAAKLFQRTEEQLSRYSIDELIAKRSLIESKQNHRGNIDVYIDGEITQINADLLHLPAESGLS
LILVVSHKHEANEQRIHDLESAVEALSAFAFEGDKQKLNSLSLVGGDIAQLATKANENKEDKGTIMRELIVDGMISGLSY
WEESTGQTKYTLAEESGLWRVYLDRSTLQTRTLDKYLRVETLPKTPRWRTVISTLEYILEHCEQYNDQRDKLVRIKDKLQ
ILISNN

Sequences:

>Translated_1126_residues
MDKKQHFKRLQNTLMIAFLVLSITPLSLIAIFFLHSHSQDLATQSTAHLVSLRDNKEQQITNYFKGRKSEVLGFARSELA
NASGGRFYGLVSAFPHLGTSIEDARKNAQLRYITGSGDKIRTSVLPESDSYIGSERYRLLHKRYHWAYLELLKRSDFSDV
LLVDINGNVVYSKAKEDNYGTNLLTGKYKDSTLADTYKKIRTLMKKPESEDNIPIIFSDFNTINNETVAWFAAPIVQQGY
LHSFALFKLPNTGLIELIGDNTDTSSIKTYFVGQDSYSRISNEDIEKNLSENMKLALSGESNVGSFIDKHGEKVLAAFTS
INVDGHLWGLSLELPEKEAFARIQQLEQIFVIAMIIAIVCVVIASHFLSNSITAPLLRLTWAAERVSAGDLDQEMISTDR
KDEIGRLAVSFARMQRSIREKIQLIKDQNEELEANLATIQLKNNELEAADKLKDEFLATTSHELRTPLHGMVGIAEALYT
GANGPISASHRHQLEIIINSGQRLTSLVNDLLDYHKMRHGNLDINKHVTDLSSATSLVLELSQHLLGNKSIRIINQVDKS
LPVVFVDEQRLEQVLYNLIGNAIKYTSEGKIVISASVVDQFLRVQVVDTGHGIPADELEHIFEPLIQAGHDSNRYRQGSG
LGLSISRQLIELMGGSLYVSSQPMVGATFSFTLPLATKEQIQQHKLLAQEGITHYQTPEKLEYNLDEIDEELPENPEGPL
LLVADDEPVNLQVLTSFLKLEGYRVKVANDGPETLKVFEEEKPELLLLDVMMPGMSGYEVCQSLRETYSHSELPIIMLTA
LNQTQDRIRGFESGANDYLSKPFNKQELAARIKAHLKASKAELFLSENDRLQQEIRHREKVEASLLETQAHILEQLNHAQ
EAIICAKSDGKIKYVNNSAAKLFQRTEEQLSRYSIDELIAKRSLIESKQNHRGNIDVYIDGEITQINADLLHLPAESGLS
LILVVSHKHEANEQRIHDLESAVEALSAFAFEGDKQKLNSLSLVGGDIAQLATKANENKEDKGTIMRELIVDGMISGLSY
WEESTGQTKYTLAEESGLWRVYLDRSTLQTRTLDKYLRVETLPKTPRWRTVISTLEYILEHCEQYNDQRDKLVRIKDKLQ
ILISNN
>Mature_1126_residues
MDKKQHFKRLQNTLMIAFLVLSITPLSLIAIFFLHSHSQDLATQSTAHLVSLRDNKEQQITNYFKGRKSEVLGFARSELA
NASGGRFYGLVSAFPHLGTSIEDARKNAQLRYITGSGDKIRTSVLPESDSYIGSERYRLLHKRYHWAYLELLKRSDFSDV
LLVDINGNVVYSKAKEDNYGTNLLTGKYKDSTLADTYKKIRTLMKKPESEDNIPIIFSDFNTINNETVAWFAAPIVQQGY
LHSFALFKLPNTGLIELIGDNTDTSSIKTYFVGQDSYSRISNEDIEKNLSENMKLALSGESNVGSFIDKHGEKVLAAFTS
INVDGHLWGLSLELPEKEAFARIQQLEQIFVIAMIIAIVCVVIASHFLSNSITAPLLRLTWAAERVSAGDLDQEMISTDR
KDEIGRLAVSFARMQRSIREKIQLIKDQNEELEANLATIQLKNNELEAADKLKDEFLATTSHELRTPLHGMVGIAEALYT
GANGPISASHRHQLEIIINSGQRLTSLVNDLLDYHKMRHGNLDINKHVTDLSSATSLVLELSQHLLGNKSIRIINQVDKS
LPVVFVDEQRLEQVLYNLIGNAIKYTSEGKIVISASVVDQFLRVQVVDTGHGIPADELEHIFEPLIQAGHDSNRYRQGSG
LGLSISRQLIELMGGSLYVSSQPMVGATFSFTLPLATKEQIQQHKLLAQEGITHYQTPEKLEYNLDEIDEELPENPEGPL
LLVADDEPVNLQVLTSFLKLEGYRVKVANDGPETLKVFEEEKPELLLLDVMMPGMSGYEVCQSLRETYSHSELPIIMLTA
LNQTQDRIRGFESGANDYLSKPFNKQELAARIKAHLKASKAELFLSENDRLQQEIRHREKVEASLLETQAHILEQLNHAQ
EAIICAKSDGKIKYVNNSAAKLFQRTEEQLSRYSIDELIAKRSLIESKQNHRGNIDVYIDGEITQINADLLHLPAESGLS
LILVVSHKHEANEQRIHDLESAVEALSAFAFEGDKQKLNSLSLVGGDIAQLATKANENKEDKGTIMRELIVDGMISGLSY
WEESTGQTKYTLAEESGLWRVYLDRSTLQTRTLDKYLRVETLPKTPRWRTVISTLEYILEHCEQYNDQRDKLVRIKDKLQ
ILISNN

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=393, Percent_Identity=31.8066157760814, Blast_Score=178, Evalue=2e-45,
Organism=Escherichia coli, GI48994928, Length=396, Percent_Identity=31.8181818181818, Blast_Score=174, Evalue=3e-44,
Organism=Escherichia coli, GI87081816, Length=453, Percent_Identity=27.8145695364238, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI1789149, Length=373, Percent_Identity=31.0991957104558, Blast_Score=154, Evalue=4e-38,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=34.156378600823, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=31.390134529148, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788393, Length=306, Percent_Identity=27.1241830065359, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=30.9623430962343, Blast_Score=103, Evalue=6e-23,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=31.25, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1788394, Length=267, Percent_Identity=29.2134831460674, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=38.9830508474576, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=37.2881355932203, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1789809, Length=123, Percent_Identity=38.2113821138211, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787894, Length=303, Percent_Identity=29.042904290429, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1790860, Length=119, Percent_Identity=36.1344537815126, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI2367329, Length=120, Percent_Identity=45.8333333333333, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=27.8026905829596, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1786784, Length=127, Percent_Identity=33.8582677165354, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790863, Length=115, Percent_Identity=35.6521739130435, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=263, Percent_Identity=29.6577946768061, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1787229, Length=113, Percent_Identity=35.3982300884956, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI1786783, Length=377, Percent_Identity=21.7506631299735, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1788550, Length=138, Percent_Identity=29.7101449275362, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1790300, Length=228, Percent_Identity=29.8245614035088, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786911, Length=121, Percent_Identity=34.7107438016529, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=27.8969957081545, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1790861, Length=205, Percent_Identity=28.780487804878, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI1789402, Length=138, Percent_Identity=28.9855072463768, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=30.7017543859649, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI145693140, Length=102, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=80, Percent_Identity=41.25, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=117, Percent_Identity=31.6239316239316, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 126824; Mature: 126824

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKQHFKRLQNTLMIAFLVLSITPLSLIAIFFLHSHSQDLATQSTAHLVSLRDNKEQQI
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCHHHH
TNYFKGRKSEVLGFARSELANASGGRFYGLVSAFPHLGTSIEDARKNAQLRYITGSGDKI
HHHHCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCHHHHHCCCEEEEEECCCCEE
RTSVLPESDSYIGSERYRLLHKRYHWAYLELLKRSDFSDVLLVDINGNVVYSKAKEDNYG
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCC
TNLLTGKYKDSTLADTYKKIRTLMKKPESEDNIPIIFSDFNTINNETVAWFAAPIVQQGY
CCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEHHHHHHHHHHCC
LHSFALFKLPNTGLIELIGDNTDTSSIKTYFVGQDSYSRISNEDIEKNLSENMKLALSGE
HHHEEEEECCCCCEEEEECCCCCCCCEEEEEECCCHHHHCCCHHHHHHHCCCCEEEEECC
SNVGSFIDKHGEKVLAAFTSINVDGHLWGLSLELPEKEAFARIQQLEQIFVIAMIIAIVC
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VVIASHFLSNSITAPLLRLTWAAERVSAGDLDQEMISTDRKDEIGRLAVSFARMQRSIRE
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
KIQLIKDQNEELEANLATIQLKNNELEAADKLKDEFLATTSHELRTPLHGMVGIAEALYT
HHHHHHCCCCHHCCEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHC
GANGPISASHRHQLEIIINSGQRLTSLVNDLLDYHKMRHGNLDINKHVTDLSSATSLVLE
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LSQHLLGNKSIRIINQVDKSLPVVFVDEQRLEQVLYNLIGNAIKYTSEGKIVISASVVDQ
HHHHHHCCCCEEHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEHHHHHH
FLRVQVVDTGHGIPADELEHIFEPLIQAGHDSNRYRQGSGLGLSISRQLIELMGGSLYVS
HHEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHCCEEEEE
SQPMVGATFSFTLPLATKEQIQQHKLLAQEGITHYQTPEKLEYNLDEIDEELPENPEGPL
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHCCCCCCCCE
LLVADDEPVNLQVLTSFLKLEGYRVKVANDGPETLKVFEEEKPELLLLDVMMPGMSGYEV
EEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCHHHH
CQSLRETYSHSELPIIMLTALNQTQDRIRGFESGANDYLSKPFNKQELAARIKAHLKASK
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHH
AELFLSENDRLQQEIRHREKVEASLLETQAHILEQLNHAQEAIICAKSDGKIKYVNNSAA
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCEEEEECCHHH
KLFQRTEEQLSRYSIDELIAKRSLIESKQNHRGNIDVYIDGEITQINADLLHLPAESGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCEECCCCCCCE
LILVVSHKHEANEQRIHDLESAVEALSAFAFEGDKQKLNSLSLVGGDIAQLATKANENKE
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCCC
DKGTIMRELIVDGMISGLSYWEESTGQTKYTLAEESGLWRVYLDRSTLQTRTLDKYLRVE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHH
TLPKTPRWRTVISTLEYILEHCEQYNDQRDKLVRIKDKLQILISNN
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCEEEEEECC
>Mature Secondary Structure
MDKKQHFKRLQNTLMIAFLVLSITPLSLIAIFFLHSHSQDLATQSTAHLVSLRDNKEQQI
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCHHHH
TNYFKGRKSEVLGFARSELANASGGRFYGLVSAFPHLGTSIEDARKNAQLRYITGSGDKI
HHHHCCCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCHHHHHCCCEEEEEECCCCEE
RTSVLPESDSYIGSERYRLLHKRYHWAYLELLKRSDFSDVLLVDINGNVVYSKAKEDNYG
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCCC
TNLLTGKYKDSTLADTYKKIRTLMKKPESEDNIPIIFSDFNTINNETVAWFAAPIVQQGY
CCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEEHHHHHHHHHHCC
LHSFALFKLPNTGLIELIGDNTDTSSIKTYFVGQDSYSRISNEDIEKNLSENMKLALSGE
HHHEEEEECCCCCEEEEECCCCCCCCEEEEEECCCHHHHCCCHHHHHHHCCCCEEEEECC
SNVGSFIDKHGEKVLAAFTSINVDGHLWGLSLELPEKEAFARIQQLEQIFVIAMIIAIVC
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VVIASHFLSNSITAPLLRLTWAAERVSAGDLDQEMISTDRKDEIGRLAVSFARMQRSIRE
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
KIQLIKDQNEELEANLATIQLKNNELEAADKLKDEFLATTSHELRTPLHGMVGIAEALYT
HHHHHHCCCCHHCCEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHC
GANGPISASHRHQLEIIINSGQRLTSLVNDLLDYHKMRHGNLDINKHVTDLSSATSLVLE
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LSQHLLGNKSIRIINQVDKSLPVVFVDEQRLEQVLYNLIGNAIKYTSEGKIVISASVVDQ
HHHHHHCCCCEEHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEHHHHHH
FLRVQVVDTGHGIPADELEHIFEPLIQAGHDSNRYRQGSGLGLSISRQLIELMGGSLYVS
HHEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHCCEEEEE
SQPMVGATFSFTLPLATKEQIQQHKLLAQEGITHYQTPEKLEYNLDEIDEELPENPEGPL
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHCCCCCCCCE
LLVADDEPVNLQVLTSFLKLEGYRVKVANDGPETLKVFEEEKPELLLLDVMMPGMSGYEV
EEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCHHHH
CQSLRETYSHSELPIIMLTALNQTQDRIRGFESGANDYLSKPFNKQELAARIKAHLKASK
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHH
AELFLSENDRLQQEIRHREKVEASLLETQAHILEQLNHAQEAIICAKSDGKIKYVNNSAA
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCEEEEECCHHH
KLFQRTEEQLSRYSIDELIAKRSLIESKQNHRGNIDVYIDGEITQINADLLHLPAESGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCEECCCCCCCE
LILVVSHKHEANEQRIHDLESAVEALSAFAFEGDKQKLNSLSLVGGDIAQLATKANENKE
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCCC
DKGTIMRELIVDGMISGLSYWEESTGQTKYTLAEESGLWRVYLDRSTLQTRTLDKYLRVE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHH
TLPKTPRWRTVISTLEYILEHCEQYNDQRDKLVRIKDKLQILISNN
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA