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The map label for this gene is rsmC

Identifier: 59712744

GI number: 59712744

Start: 2386004

End: 2387023

Strand: Direct

Name: rsmC

Synonym: VF_2137

Alternate gene names: 59712744

Gene position: 2386004-2387023 (Clockwise)

Preceding gene: 59712743

Following gene: 59712745

Centisome position: 82.35

GC content: 36.57

Gene sequence:

>1020_bases
ATGTCTTACTCTGCACCAAGTCAAATTACTCAACGCCAACTTGCTTACTTTGAAGGCAAGCATGTTCTCATTGCTGGTGA
GTTAATCGATGACTTTCCTTTTGAGCTAGCAAAGCATTGTGAATCAACCTCAATTTTCACAACAAATTACTCATACTATA
AGCAATTTGCTGGGCATAATTCTATTCAATGTTATTTTGGTTCTGAATTAACAGAGCCGACTAATGTCGACATGATCTTA
CTCTACTGGCCTAAAGCGAAAGCAGAAGCGGAATACTTACTGACTATGCTGCTAGCAAAACTGGGTAAAAACACGGAAAT
TGTTGTTGTTGGTGAAAACCGAAGTGGTGTAAAAAGCATTGAAAAAATGTTTGCTGATTTTGGCCCGATAAATAAATTTG
ATTCAGCTCGTCGTTGTAGCTTTTATTGGGGTCAGTGCACTGAAGAAGCACCAACATTCAATCAACAAGATTGGTTTAAA
GAATACCAAGTTGAATTTGAAAACCACACTATAGAAGTAAGAAGCTTACCTGGTGTATTTAGCCATGGTGAATTTGATAA
AGGTTCTGAGCTTTTACTGCAAACCTTACCTGCACTACGAGGTCATGTACTTGATTTTGGGTGTGGTGCAGGTGTGATTG
GCTCGGTAATGAAAACAATCAACCCTAAAATTCACTTAGATATGGTTGATATCAGTGCGCTTGCAATAGCCTCGTCTATT
GAAACGTTAAAAGCTAATAACCTTGAAGGCAATGTATTTGCAAGTGACGTGTATTCTGATACGAAAGAGAATTACCAATT
TATTGTCAGTAATCCTCCTTTTCATGCTGGTCTAAAAACACATTACTCTTCAACAGAAGAACTATTAGAAAAAGCACCAC
AAAATCTAACCCATGAAGGACAATTAATTTTAGTGGCCAATAGCTTTTTACAGTACCCACCAATCATTGAAAAAGCATTT
GGTGAGTGTTTAACATTAGCTAAAAATAACAAATTTAAGATCTATTCAGCTCAAAAATAA

Upstream 100 bases:

>100_bases
TTAAGGCCACTGATTTTCATCATCTTCAGTGGCCTTTTCTTTTCCTTCAAAGCACTTTGTGGGACAATCCTGCCAGTTTT
TATATTATTTCGAGGCCATA

Downstream 100 bases:

>100_bases
TTCTTGCCTCCCGCCGCACTTTATCACTCTGCTGCTTGATTTTTAACATGAATTAAGTATAAGAAGCAGCAGAGTTTCTC
GTTAAAATCAAACTCAATAA

Product: 16S rRNA m2G1207 methylase

Products: NA

Alternate protein names: 16S rRNA m2G1207 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rsmC

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSYSAPSQITQRQLAYFEGKHVLIAGELIDDFPFELAKHCESTSIFTTNYSYYKQFAGHNSIQCYFGSELTEPTNVDMIL
LYWPKAKAEAEYLLTMLLAKLGKNTEIVVVGENRSGVKSIEKMFADFGPINKFDSARRCSFYWGQCTEEAPTFNQQDWFK
EYQVEFENHTIEVRSLPGVFSHGEFDKGSELLLQTLPALRGHVLDFGCGAGVIGSVMKTINPKIHLDMVDISALAIASSI
ETLKANNLEGNVFASDVYSDTKENYQFIVSNPPFHAGLKTHYSSTEELLEKAPQNLTHEGQLILVANSFLQYPPIIEKAF
GECLTLAKNNKFKIYSAQK

Sequences:

>Translated_339_residues
MSYSAPSQITQRQLAYFEGKHVLIAGELIDDFPFELAKHCESTSIFTTNYSYYKQFAGHNSIQCYFGSELTEPTNVDMIL
LYWPKAKAEAEYLLTMLLAKLGKNTEIVVVGENRSGVKSIEKMFADFGPINKFDSARRCSFYWGQCTEEAPTFNQQDWFK
EYQVEFENHTIEVRSLPGVFSHGEFDKGSELLLQTLPALRGHVLDFGCGAGVIGSVMKTINPKIHLDMVDISALAIASSI
ETLKANNLEGNVFASDVYSDTKENYQFIVSNPPFHAGLKTHYSSTEELLEKAPQNLTHEGQLILVANSFLQYPPIIEKAF
GECLTLAKNNKFKIYSAQK
>Mature_338_residues
SYSAPSQITQRQLAYFEGKHVLIAGELIDDFPFELAKHCESTSIFTTNYSYYKQFAGHNSIQCYFGSELTEPTNVDMILL
YWPKAKAEAEYLLTMLLAKLGKNTEIVVVGENRSGVKSIEKMFADFGPINKFDSARRCSFYWGQCTEEAPTFNQQDWFKE
YQVEFENHTIEVRSLPGVFSHGEFDKGSELLLQTLPALRGHVLDFGCGAGVIGSVMKTINPKIHLDMVDISALAIASSIE
TLKANNLEGNVFASDVYSDTKENYQFIVSNPPFHAGLKTHYSSTEELLEKAPQNLTHEGQLILVANSFLQYPPIIEKAFG
ECLTLAKNNKFKIYSAQK

Specific function: Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmC family

Homologues:

Organism=Escherichia coli, GI1790830, Length=339, Percent_Identity=40.117994100295, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI87082206, Length=334, Percent_Identity=27.2455089820359, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMC_VIBF1 (Q5E2W4)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205520.1
- ProteinModelPortal:   Q5E2W4
- SMR:   Q5E2W4
- STRING:   Q5E2W4
- GeneID:   3279299
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_2137
- NMPDR:   fig|312309.3.peg.2137
- eggNOG:   COG2813
- HOGENOM:   HBG296757
- OMA:   TGKFKVY
- PhylomeDB:   Q5E2W4
- ProtClustDB:   CLSK874045
- BioCyc:   VFIS312309:VF2137-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01862
- InterPro:   IPR002052
- InterPro:   IPR013675
- InterPro:   IPR007848

Pfam domain/function: PF05175 MTS; PF08468 MTS_N

EC number: =2.1.1.172

Molecular weight: Translated: 38100; Mature: 37968

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSAPSQITQRQLAYFEGKHVLIAGELIDDFPFELAKHCESTSIFTTNYSYYKQFAGHN
CCCCCHHHHHHHHHHHHCCCEEEEECCHHHCCHHHHHHHCCCCEEEEECHHHHHHHCCCC
SIQCYFGSELTEPTNVDMILLYWPKAKAEAEYLLTMLLAKLGKNTEIVVVGENRSGVKSI
CEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
EKMFADFGPINKFDSARRCSFYWGQCTEEAPTFNQQDWFKEYQVEFENHTIEVRSLPGVF
HHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHEEECCCEEEEEECCCCC
SHGEFDKGSELLLQTLPALRGHVLDFGCGAGVIGSVMKTINPKIHLDMVDISALAIASSI
CCCCCCCHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHH
ETLKANNLEGNVFASDVYSDTKENYQFIVSNPPFHAGLKTHYSSTEELLEKAPQNLTHEG
HHHHCCCCCCCEEEHHHHCCCCCCCEEEECCCCCCCCHHHHCCCHHHHHHHCCCCCCCCC
QLILVANSFLQYPPIIEKAFGECLTLAKNNKFKIYSAQK
CEEEEECCHHCCCCHHHHHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
SYSAPSQITQRQLAYFEGKHVLIAGELIDDFPFELAKHCESTSIFTTNYSYYKQFAGHN
CCCCHHHHHHHHHHHHCCCEEEEECCHHHCCHHHHHHHCCCCEEEEECHHHHHHHCCCC
SIQCYFGSELTEPTNVDMILLYWPKAKAEAEYLLTMLLAKLGKNTEIVVVGENRSGVKSI
CEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
EKMFADFGPINKFDSARRCSFYWGQCTEEAPTFNQQDWFKEYQVEFENHTIEVRSLPGVF
HHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHEEECCCEEEEEECCCCC
SHGEFDKGSELLLQTLPALRGHVLDFGCGAGVIGSVMKTINPKIHLDMVDISALAIASSI
CCCCCCCHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHH
ETLKANNLEGNVFASDVYSDTKENYQFIVSNPPFHAGLKTHYSSTEELLEKAPQNLTHEG
HHHHCCCCCCCEEEHHHHCCCCCCCEEEECCCCCCCCHHHHCCCHHHHHHHCCCCCCCCC
QLILVANSFLQYPPIIEKAFGECLTLAKNNKFKIYSAQK
CEEEEECCHHCCCCHHHHHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA