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The map label for this gene is rpiA [H]

Identifier: 59712712

GI number: 59712712

Start: 2340005

End: 2340661

Strand: Direct

Name: rpiA [H]

Synonym: VF_2105

Alternate gene names: 59712712

Gene position: 2340005-2340661 (Clockwise)

Preceding gene: 59712711

Following gene: 59712713

Centisome position: 80.76

GC content: 41.7

Gene sequence:

>657_bases
ATGACTCAAGACGAGATGAAAAAAGCAGCTGGTTGGGCAGCGTTAGAATACGTAGAAGCTGGCAGCATTGTTGGTGTGGG
TACAGGTTCAACCGTAAACCATTTCATCGACGCACTTGCGACCATGAAGAATGAAATTAAAGGCGCAGTATCAAGCTCAG
TAGCTTCAACAGAGAAGTTAAAAGAACTGGGTATTGAAGTTTTTGATTGTAATGATGTTGCAGGCCTTGATGTTTATGTT
GATGGTGCCGACGAAATTAACGGCAAGAATGAAATGATTAAAGGCGGCGGCGCTGCTCTTACTCGTGAAAAAATCGTTGC
TGCAATTTCTGATAAATTTATCTGTATTGTTGATGACACAAAGCAAGTTGATGTTTTAGGTCAATTCCCACTTCCTGTTG
AAGTTATTCCAATGGCTCGCTCTTATGTTGCTCGTGAGTTAGTTAAATTAGGTGGCGATCCTGCATACCGTGAAGGCGTA
ATTACCGATAATGGTAATGTGATCCTTGATGTTCACGGTATGAAAATTACAGATGCAAAAGATCTAGAAGATAAAATCAA
TGCTCTTCCAGGCGTAGTAACTGTAGGTTTATTTGCACACCGCGGTGCAGATGTCCTATTAGTAGGGGCTCCAGAAGGCG
TTAAGAAGTTCGACTAA

Upstream 100 bases:

>100_bases
ATTTTTTACGCTTTACTGACTTATTTTTTCTGACGAAGAAAAAACTCTACGCTATAATCACGCCGCTTTCATTTGCACAT
TATATTTCTAGGAGAAGGTC

Downstream 100 bases:

>100_bases
ATAACTACCTTAACTTAATGTTCCCTTATTTAAGAGGGAGCAAAAATGTTATTTCATTACAAACGGTGCTCATTAGCACC
GTTTTTTATTAACTATTCCG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTQDEMKKAAGWAALEYVEAGSIVGVGTGSTVNHFIDALATMKNEIKGAVSSSVASTEKLKELGIEVFDCNDVAGLDVYV
DGADEINGKNEMIKGGGAALTREKIVAAISDKFICIVDDTKQVDVLGQFPLPVEVIPMARSYVARELVKLGGDPAYREGV
ITDNGNVILDVHGMKITDAKDLEDKINALPGVVTVGLFAHRGADVLLVGAPEGVKKFD

Sequences:

>Translated_218_residues
MTQDEMKKAAGWAALEYVEAGSIVGVGTGSTVNHFIDALATMKNEIKGAVSSSVASTEKLKELGIEVFDCNDVAGLDVYV
DGADEINGKNEMIKGGGAALTREKIVAAISDKFICIVDDTKQVDVLGQFPLPVEVIPMARSYVARELVKLGGDPAYREGV
ITDNGNVILDVHGMKITDAKDLEDKINALPGVVTVGLFAHRGADVLLVGAPEGVKKFD
>Mature_217_residues
TQDEMKKAAGWAALEYVEAGSIVGVGTGSTVNHFIDALATMKNEIKGAVSSSVASTEKLKELGIEVFDCNDVAGLDVYVD
GADEINGKNEMIKGGGAALTREKIVAAISDKFICIVDDTKQVDVLGQFPLPVEVIPMARSYVARELVKLGGDPAYREGVI
TDNGNVILDVHGMKITDAKDLEDKINALPGVVTVGLFAHRGADVLLVGAPEGVKKFD

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=209, Percent_Identity=36.3636363636364, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1789280, Length=215, Percent_Identity=74.8837209302326, Blast_Score=333, Evalue=5e-93,
Organism=Caenorhabditis elegans, GI17551758, Length=214, Percent_Identity=35.5140186915888, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324669, Length=225, Percent_Identity=29.3333333333333, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281364072, Length=203, Percent_Identity=32.0197044334975, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23005; Mature: 22873

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDEMKKAAGWAALEYVEAGSIVGVGTGSTVNHFIDALATMKNEIKGAVSSSVASTEKL
CCHHHHHHHHCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELGIEVFDCNDVAGLDVYVDGADEINGKNEMIKGGGAALTREKIVAAISDKFICIVDDT
HHCCCEEEECCCCCCEEEEECCCHHCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEECCC
KQVDVLGQFPLPVEVIPMARSYVARELVKLGGDPAYREGVITDNGNVILDVHGMKITDAK
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCEEECCCCEEEEECCEEECCCH
DLEDKINALPGVVTVGLFAHRGADVLLVGAPEGVKKFD
HHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TQDEMKKAAGWAALEYVEAGSIVGVGTGSTVNHFIDALATMKNEIKGAVSSSVASTEKL
CHHHHHHHHCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KELGIEVFDCNDVAGLDVYVDGADEINGKNEMIKGGGAALTREKIVAAISDKFICIVDDT
HHCCCEEEECCCCCCEEEEECCCHHCCCCCCEECCCCCHHHHHHHHHHHCCCEEEEECCC
KQVDVLGQFPLPVEVIPMARSYVARELVKLGGDPAYREGVITDNGNVILDVHGMKITDAK
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCEEECCCCEEEEECCEEECCCH
DLEDKINALPGVVTVGLFAHRGADVLLVGAPEGVKKFD
HHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA