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The map label for this gene is visC [H]

Identifier: 59712707

GI number: 59712707

Start: 2335510

End: 2336718

Strand: Reverse

Name: visC [H]

Synonym: VF_2100

Alternate gene names: 59712707

Gene position: 2336718-2335510 (Counterclockwise)

Preceding gene: 59712708

Following gene: 172087753

Centisome position: 80.65

GC content: 40.12

Gene sequence:

>1209_bases
ATGATGCAGAGTGTAGATATTGCGATTATTGGTGGCGGTATGGTTGGTTTAACCGTAGCCGCTGCATTAGAAAACAGTGG
ATTAAGAATCGCAGTCATTGAAAGCCAACTGCCTGAAGAGGAATTAGCCTCTTTACCTGATATTCGAGTTTCAGCGATCA
GTCGAGCAAGTGAAAATATTTTAAATAATGTTGGAGCATGGCAGGGAATCTTGTCACGTCGTGCAGCACCATACACATCG
ATGCGAGTATGGGAGCAAGACAGCTTTGCTAAGATTGAATTTGAAGCAGAGGACATCGCTCAGCATAATTTAGGACATAT
TGTCGAAAACCGAGTTATACAACTTTCTCTTTTGGATAAAATTTCAAAACAAGAAAACGTTACATTATTAGCGCCAGAAC
GATGCACTAATATTATGTTTGGCGAAAGTGAAGCTTGGATTAATTTAGAATCAGGTAAAGCAATTACCGCAAAGTTGGTG
GTTGGTGCGGATGGTGCAAATTCATGGTTACGTAATCAGTTAGATATTCCTTTAACACATTGGGATTACGGTCATAGCGC
TCTGGTTGCAAATATTCGAACTGTAGATACTCATAATGCAACCGCTCGACAAATATTTAGACCTGAAGGACCGCTTGCAT
TTTTACCATTAGGTGAACCGAATTTAAGCTCTATTGTATGGTCTCTTGACCCTTTACAAGCCGAAGATTTAGTTTCGATG
CCTGAAGATGATTTCAATAAACGTTTAACTACGGCATTTGATAATCAACTTGGGCTATGTTCTGTTGAAGGGACTCGCCA
AGCTTTTCCATTAAAGATGCGTTATGCCAAAGATTTCGTTCGTGAGCGAGCGGTATTAGTCGGTGATGCTGCGCATACTA
TTCATCCTTTAGCTGGGCAAGGTGTGAATCTTGGACTTGCCGATGCTGCTGCATTAGCTGAAACGATTTTAGCGTTACAA
AATGAAAGTAAAGACATCGGTTTAAAAGTTAATTTACGTTCTTTTGAGCGATGGAGAAAAGCAGAAGCCGCTCAAATGAT
TGCCTCTATGCAAGGATTTAAAGAGTTATTTTCTGGAAGCAATCCAGTTAAGAAGTTCATTCGAGGGGTGGGAATGTCAT
TAACGAATGAGCTATCGCCTGTTAAAGATGAATGCTTAAAAAGAGCGCTAGGCTTATCTGGACATTTACCAGAAATAGCA
AAAAAATAG

Upstream 100 bases:

>100_bases
TGGTAATTGGACGAAATATTGGTTTGTATGCGGTTGATACTTTCCGTTTTTTATTAAAACCCGCGACATTACGAGCAATG
GGTAGAGTGAAAAGATAATT

Downstream 100 bases:

>100_bases
TATTTAGTTAAAAACAAAAAAGGTAGCGTAATGCTACCTTTATTTTTAATAAGCCATTTTCAACCGAGTTATTTCTGAGT
TAATTTCTTTTACCATTTTA

Product: 2-octaprenyl-6-methoxyphenol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MMQSVDIAIIGGGMVGLTVAAALENSGLRIAVIESQLPEEELASLPDIRVSAISRASENILNNVGAWQGILSRRAAPYTS
MRVWEQDSFAKIEFEAEDIAQHNLGHIVENRVIQLSLLDKISKQENVTLLAPERCTNIMFGESEAWINLESGKAITAKLV
VGADGANSWLRNQLDIPLTHWDYGHSALVANIRTVDTHNATARQIFRPEGPLAFLPLGEPNLSSIVWSLDPLQAEDLVSM
PEDDFNKRLTTAFDNQLGLCSVEGTRQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQGVNLGLADAAALAETILALQ
NESKDIGLKVNLRSFERWRKAEAAQMIASMQGFKELFSGSNPVKKFIRGVGMSLTNELSPVKDECLKRALGLSGHLPEIA
KK

Sequences:

>Translated_402_residues
MMQSVDIAIIGGGMVGLTVAAALENSGLRIAVIESQLPEEELASLPDIRVSAISRASENILNNVGAWQGILSRRAAPYTS
MRVWEQDSFAKIEFEAEDIAQHNLGHIVENRVIQLSLLDKISKQENVTLLAPERCTNIMFGESEAWINLESGKAITAKLV
VGADGANSWLRNQLDIPLTHWDYGHSALVANIRTVDTHNATARQIFRPEGPLAFLPLGEPNLSSIVWSLDPLQAEDLVSM
PEDDFNKRLTTAFDNQLGLCSVEGTRQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQGVNLGLADAAALAETILALQ
NESKDIGLKVNLRSFERWRKAEAAQMIASMQGFKELFSGSNPVKKFIRGVGMSLTNELSPVKDECLKRALGLSGHLPEIA
KK
>Mature_402_residues
MMQSVDIAIIGGGMVGLTVAAALENSGLRIAVIESQLPEEELASLPDIRVSAISRASENILNNVGAWQGILSRRAAPYTS
MRVWEQDSFAKIEFEAEDIAQHNLGHIVENRVIQLSLLDKISKQENVTLLAPERCTNIMFGESEAWINLESGKAITAKLV
VGADGANSWLRNQLDIPLTHWDYGHSALVANIRTVDTHNATARQIFRPEGPLAFLPLGEPNLSSIVWSLDPLQAEDLVSM
PEDDFNKRLTTAFDNQLGLCSVEGTRQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQGVNLGLADAAALAETILALQ
NESKDIGLKVNLRSFERWRKAEAAQMIASMQGFKELFSGSNPVKKFIRGVGMSLTNELSPVKDECLKRALGLSGHLPEIA
KK

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=393, Percent_Identity=32.3155216284987, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI32967307, Length=350, Percent_Identity=32, Blast_Score=161, Evalue=1e-39,
Organism=Escherichia coli, GI1789273, Length=398, Percent_Identity=54.7738693467337, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI1786883, Length=391, Percent_Identity=35.5498721227622, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1789274, Length=390, Percent_Identity=31.025641025641, Blast_Score=189, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI25146631, Length=426, Percent_Identity=31.4553990610329, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6321694, Length=449, Percent_Identity=26.5033407572383, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19920760, Length=422, Percent_Identity=31.2796208530806, Blast_Score=175, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 43937; Mature: 43937

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQSVDIAIIGGGMVGLTVAAALENSGLRIAVIESQLPEEELASLPDIRVSAISRASENI
CCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHH
LNNVGAWQGILSRRAAPYTSMRVWEQDSFAKIEFEAEDIAQHNLGHIVENRVIQLSLLDK
HHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHHEEEEHHHHH
ISKQENVTLLAPERCTNIMFGESEAWINLESGKAITAKLVVGADGANSWLRNQLDIPLTH
HCCCCCEEEECHHHHCCEEECCCCCEEEECCCCEEEEEEEEECCCCCHHHHCCCCCCEEE
WDYGHSALVANIRTVDTHNATARQIFRPEGPLAFLPLGEPNLSSIVWSLDPLQAEDLVSM
CCCCCCEEEEEEEEECCCCHHHHHHCCCCCCEEEEECCCCCHHHHEEECCCCCHHHHHCC
PEDDFNKRLTTAFDNQLGLCSVEGTRQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQ
CCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCHHHHCCCCCC
GVNLGLADAAALAETILALQNESKDIGLKVNLRSFERWRKAEAAQMIASMQGFKELFSGS
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPVKKFIRGVGMSLTNELSPVKDECLKRALGLSGHLPEIAKK
CHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCCCCHHHHCC
>Mature Secondary Structure
MMQSVDIAIIGGGMVGLTVAAALENSGLRIAVIESQLPEEELASLPDIRVSAISRASENI
CCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHH
LNNVGAWQGILSRRAAPYTSMRVWEQDSFAKIEFEAEDIAQHNLGHIVENRVIQLSLLDK
HHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHHHHEEEEHHHHH
ISKQENVTLLAPERCTNIMFGESEAWINLESGKAITAKLVVGADGANSWLRNQLDIPLTH
HCCCCCEEEECHHHHCCEEECCCCCEEEECCCCEEEEEEEEECCCCCHHHHCCCCCCEEE
WDYGHSALVANIRTVDTHNATARQIFRPEGPLAFLPLGEPNLSSIVWSLDPLQAEDLVSM
CCCCCCEEEEEEEEECCCCHHHHHHCCCCCCEEEEECCCCCHHHHEEECCCCCHHHHHCC
PEDDFNKRLTTAFDNQLGLCSVEGTRQAFPLKMRYAKDFVRERAVLVGDAAHTIHPLAGQ
CCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCHHHHCCCCCC
GVNLGLADAAALAETILALQNESKDIGLKVNLRSFERWRKAEAAQMIASMQGFKELFSGS
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NPVKKFIRGVGMSLTNELSPVKDECLKRALGLSGHLPEIAKK
CHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]