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The map label for this gene is skp [H]

Identifier: 59712560

GI number: 59712560

Start: 2182081

End: 2182596

Strand: Reverse

Name: skp [H]

Synonym: VF_1953

Alternate gene names: 59712560

Gene position: 2182596-2182081 (Counterclockwise)

Preceding gene: 59712561

Following gene: 59712559

Centisome position: 75.33

GC content: 37.4

Gene sequence:

>516_bases
ATGATTTTGAAAAAATTAGTGAAAGTAGCCGCTTTAGGCGCAGTTCTGGTAAGTGGTTCTTTTTTTGCTAATGCAGCAGA
AGCCGCAACCAAAGTGGGTTATGTAAACATGGCTCAAATTGTTCAGCAAATGCCACAACGTGAAGCGATTTCAGAAAAGC
TTCGTGCTGAATTTAAAGATCGTATTGATGAGTTACGTGGTTTAGAATCAAAAATTAAAGATAAAGTTGAAACTATCAAA
CGCGATGGTGAGTTATTAGGTGCATCAGGTAAAACGAAGCTTGAGCGTGAAATCGCTTCACTTCAGTCTGATTACAAACT
AAAAGCACAAGCTTTAGATGAAGATAACCGTCGTCGTCAAGGTGAAGAGCGTCAAAAGTTAATTATGCAAGTACAACAAA
CTGTAGAGAAAGTAGCAAATAAAGAAGGCTACGATATGGTTGTTGACGCTGCAACATTGCTTTGGGCTAAACCAGAAGAC
AACCTATCAGAAAAAGTTATTAAAGCAATTAAATAA

Upstream 100 bases:

>100_bases
GTTTCACCATTGGTCGAACTTTCTAAGCATTGATAGCTCTAATAGAAAAGTGTTAATGTAAACTGTATTGGTTTATATAC
GATAATAGTTAAGTAAGGAT

Downstream 100 bases:

>100_bases
GGTTGAATATGTCTCGTATTACGCTTGCTGAATTGGCAGAAAAATTAGATGCAACAGTCCATGGTGATGGCACTGTTGTG
GTTCACTCAATCGCTTCGAT

Product: periplasmic chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MILKKLVKVAALGAVLVSGSFFANAAEAATKVGYVNMAQIVQQMPQREAISEKLRAEFKDRIDELRGLESKIKDKVETIK
RDGELLGASGKTKLEREIASLQSDYKLKAQALDEDNRRRQGEERQKLIMQVQQTVEKVANKEGYDMVVDAATLLWAKPED
NLSEKVIKAIK

Sequences:

>Translated_171_residues
MILKKLVKVAALGAVLVSGSFFANAAEAATKVGYVNMAQIVQQMPQREAISEKLRAEFKDRIDELRGLESKIKDKVETIK
RDGELLGASGKTKLEREIASLQSDYKLKAQALDEDNRRRQGEERQKLIMQVQQTVEKVANKEGYDMVVDAATLLWAKPED
NLSEKVIKAIK
>Mature_171_residues
MILKKLVKVAALGAVLVSGSFFANAAEAATKVGYVNMAQIVQQMPQREAISEKLRAEFKDRIDELRGLESKIKDKVETIK
RDGELLGASGKTKLEREIASLQSDYKLKAQALDEDNRRRQGEERQKLIMQVQQTVEKVANKEGYDMVVDAATLLWAKPED
NLSEKVIKAIK

Specific function: Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm [H]

COG id: COG2825

COG function: function code M; Outer membrane protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the skp family [H]

Homologues:

Organism=Escherichia coli, GI1786375, Length=148, Percent_Identity=33.7837837837838, Blast_Score=90, Evalue=9e-20,

Paralogues:

None

Copy number: 580 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005632 [H]

Pfam domain/function: PF03938 OmpH [H]

EC number: NA

Molecular weight: Translated: 19145; Mature: 19145

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKKLVKVAALGAVLVSGSFFANAAEAATKVGYVNMAQIVQQMPQREAISEKLRAEFKD
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHH
RIDELRGLESKIKDKVETIKRDGELLGASGKTKLEREIASLQSDYKLKAQALDEDNRRRQ
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
GEERQKLIMQVQQTVEKVANKEGYDMVVDAATLLWAKPEDNLSEKVIKAIK
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MILKKLVKVAALGAVLVSGSFFANAAEAATKVGYVNMAQIVQQMPQREAISEKLRAEFKD
CHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHH
RIDELRGLESKIKDKVETIKRDGELLGASGKTKLEREIASLQSDYKLKAQALDEDNRRRQ
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
GEERQKLIMQVQQTVEKVANKEGYDMVVDAATLLWAKPEDNLSEKVIKAIK
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]