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The map label for this gene is lpxA [H]

Identifier: 59712557

GI number: 59712557

Start: 2179682

End: 2180470

Strand: Reverse

Name: lpxA [H]

Synonym: VF_1950

Alternate gene names: 59712557

Gene position: 2180470-2179682 (Counterclockwise)

Preceding gene: 59712558

Following gene: 59712556

Centisome position: 75.25

GC content: 40.05

Gene sequence:

>789_bases
ATGATTCATGAAACTGCTAAGATTCACCCATCAGCTGTTATTGAAGGTAACGTAACGATTGAAGCTAATGTATCTGTTGG
TCCATTTACTTACATTTCTGGTAATGTAACGATTGGCGAAGGTACGGAAGTGATGTCACATGTTGTCATCAAAGGTGATA
CAACGATTGGTAAAGATAACCGTATTTTCGCTTTTGCAATTATCGGTGAGGAAAGCCAAGACAAGAAATATGGTGGTGAA
GCAACAACAGTTGTTATCGGTGACCGTAATGTGATTCGTGAAAGTGTTCAAATTCACCGTGGTACTGTTCAAGACCGCGG
GGTAACTACAGTCGGTAGCGATAACTTACTTTGTGTTAATGTACATATTGCTCATGACTGTGTTGTTGGTGACAACATCA
TTATGGGGAATAACGCGACACTAGCGGGTCATGTAACGGTTGAAGACTTTGCTATTGTTTCTGCATTGTCACCTGTTCAT
CAGTTCTGTACGGTAGGTGCTCATAGCTTTATCGGTGGTGCTTCCGTTGTTGTTCAAGATGTACCTCCATTTGTGATGGC
ACAAGGTAACCACTGTAAACCGTTTGGTATTAATATCGAAGGCTTAAAACGTCGTGGTTTTGAAAAAGCTGAAATTCATG
CAATTCGTCGCGCTTATAAAGCACTTTACCGTAACGGTAATACGTTAGAAGAAGCAAAAGTTGAAATAAACAAAGAAATT
GAAGCGTTTCCTGTTCTTCAAGGCTTCTTAGATTTGTTTGAGAAATCAACGCGCGGTATTATTCGTTAA

Upstream 100 bases:

>100_bases
AAGATCGTCGTGGTATCGCACTATTTAACGGTGTAGCAAAAGTAGATGGCGAAGTTGTATGTTCTGCTGAGCTTAAGTGT
GCAAGACGAGAGTTTTAATT

Downstream 100 bases:

>100_bases
TAACGGCATTAAAAACAGTTAAAGTATATAAGGCCTATTCATGTAGGCCTTTTTTATTTGGAGTAAGTATGACCAAACCA
TTACGAATCGGAATTGTTGC

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MIHETAKIHPSAVIEGNVTIEANVSVGPFTYISGNVTIGEGTEVMSHVVIKGDTTIGKDNRIFAFAIIGEESQDKKYGGE
ATTVVIGDRNVIRESVQIHRGTVQDRGVTTVGSDNLLCVNVHIAHDCVVGDNIIMGNNATLAGHVTVEDFAIVSALSPVH
QFCTVGAHSFIGGASVVVQDVPPFVMAQGNHCKPFGINIEGLKRRGFEKAEIHAIRRAYKALYRNGNTLEEAKVEINKEI
EAFPVLQGFLDLFEKSTRGIIR

Sequences:

>Translated_262_residues
MIHETAKIHPSAVIEGNVTIEANVSVGPFTYISGNVTIGEGTEVMSHVVIKGDTTIGKDNRIFAFAIIGEESQDKKYGGE
ATTVVIGDRNVIRESVQIHRGTVQDRGVTTVGSDNLLCVNVHIAHDCVVGDNIIMGNNATLAGHVTVEDFAIVSALSPVH
QFCTVGAHSFIGGASVVVQDVPPFVMAQGNHCKPFGINIEGLKRRGFEKAEIHAIRRAYKALYRNGNTLEEAKVEINKEI
EAFPVLQGFLDLFEKSTRGIIR
>Mature_262_residues
MIHETAKIHPSAVIEGNVTIEANVSVGPFTYISGNVTIGEGTEVMSHVVIKGDTTIGKDNRIFAFAIIGEESQDKKYGGE
ATTVVIGDRNVIRESVQIHRGTVQDRGVTTVGSDNLLCVNVHIAHDCVVGDNIIMGNNATLAGHVTVEDFAIVSALSPVH
QFCTVGAHSFIGGASVVVQDVPPFVMAQGNHCKPFGINIEGLKRRGFEKAEIHAIRRAYKALYRNGNTLEEAKVEINKEI
EAFPVLQGFLDLFEKSTRGIIR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=262, Percent_Identity=59.5419847328244, Blast_Score=326, Evalue=9e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28289; Mature: 28289

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHETAKIHPSAVIEGNVTIEANVSVGPFTYISGNVTIGEGTEVMSHVVIKGDTTIGKDN
CCCCCCCCCCCEEEECCEEEEEECCCCCEEEEECEEEECCCHHHEEEEEEECCCEECCCC
RIFAFAIIGEESQDKKYGGEATTVVIGDRNVIRESVQIHRGTVQDRGVTTVGSDNLLCVN
CEEEEEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEE
VHIAHDCVVGDNIIMGNNATLAGHVTVEDFAIVSALSPVHQFCTVGAHSFIGGASVVVQD
EEEEEEEEECCCEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEC
VPPFVMAQGNHCKPFGINIEGLKRRGFEKAEIHAIRRAYKALYRNGNTLEEAKVEINKEI
CCCEEEECCCCCCEECCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHEEECCCC
EAFPVLQGFLDLFEKSTRGIIR
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIHETAKIHPSAVIEGNVTIEANVSVGPFTYISGNVTIGEGTEVMSHVVIKGDTTIGKDN
CCCCCCCCCCCEEEECCEEEEEECCCCCEEEEECEEEECCCHHHEEEEEEECCCEECCCC
RIFAFAIIGEESQDKKYGGEATTVVIGDRNVIRESVQIHRGTVQDRGVTTVGSDNLLCVN
CEEEEEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEE
VHIAHDCVVGDNIIMGNNATLAGHVTVEDFAIVSALSPVHQFCTVGAHSFIGGASVVVQD
EEEEEEEEECCCEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEC
VPPFVMAQGNHCKPFGINIEGLKRRGFEKAEIHAIRRAYKALYRNGNTLEEAKVEINKEI
CCCEEEECCCCCCEECCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHEEECCCC
EAFPVLQGFLDLFEKSTRGIIR
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA