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The map label for this gene is rnhB [H]

Identifier: 59712555

GI number: 59712555

Start: 2177834

End: 2178457

Strand: Reverse

Name: rnhB [H]

Synonym: VF_1948

Alternate gene names: 59712555

Gene position: 2178457-2177834 (Counterclockwise)

Preceding gene: 59712556

Following gene: 59712554

Centisome position: 75.18

GC content: 40.71

Gene sequence:

>624_bases
ATGACAAAAAAAGCAGAATCAAAAGAATTACCGCCATTTGAGTATCCAGAAGGATATCAACTTTTCGCTGGAGTTGATGA
AGTTGGTCGTGGCCCTTTAGTCGGAGCCGTTGTGACCGCTGCGGTTATTTTGGATCCTAATAACCCAATTGAAGGGTTAA
CCGATTCTAAGAAATTAACGGATAAAAAGCGTGAGTTGCTATTTCCTGAAATTCAAGAAAAAGCATTAGCGTGGTCATTA
GGTCGTTGTGAAGCGCATGAGATTGATGAATTAAATATTCTTCAAGCGACTATGGTTGCTATGCAAAGAGCGATTGCTGG
TCTTAATATTACTCCTGATTTTGCATTAATTGATGGTAATAAAGTGCCTGAATTACCAATGGCAGGGCTTGCTGTAGTAA
AAGGGGACTTACGTGTTCAAGAGATCAGCGCCGCGTCCATTATTGCAAAGGTTACTCGTGATAGAGAGATGGAGGAGTTA
GATAAAGCTTATCCTCAATATGGTTTTGCGAAGCACAAAGGCTATCCGACAAAAGCACACTTTGAAGCAATTGAAGAGCA
CGGTGTTATTTCTGAGCATCGCCGAAGTTTTAAACCCGTAAAACGCGTTTTAGGGATTGAATAA

Upstream 100 bases:

>100_bases
AAATTCACAGAAATGCATCAATGGATTAGAAAAGATGCAGATAAACAAGCCGCCAATGCCGTATTACGCCTAATTAATAA
AGAAACAGCAGAATAACCAG

Downstream 100 bases:

>100_bases
TGTCTGAACCTAAATTCGTACATTTAAGAGTTCATAGTGACTTCTCAATGGTGGATGGCTTATCTAAAGTACCACCATTG
GTAAAAAAAGTCGGTGAACT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MTKKAESKELPPFEYPEGYQLFAGVDEVGRGPLVGAVVTAAVILDPNNPIEGLTDSKKLTDKKRELLFPEIQEKALAWSL
GRCEAHEIDELNILQATMVAMQRAIAGLNITPDFALIDGNKVPELPMAGLAVVKGDLRVQEISAASIIAKVTRDREMEEL
DKAYPQYGFAKHKGYPTKAHFEAIEEHGVISEHRRSFKPVKRVLGIE

Sequences:

>Translated_207_residues
MTKKAESKELPPFEYPEGYQLFAGVDEVGRGPLVGAVVTAAVILDPNNPIEGLTDSKKLTDKKRELLFPEIQEKALAWSL
GRCEAHEIDELNILQATMVAMQRAIAGLNITPDFALIDGNKVPELPMAGLAVVKGDLRVQEISAASIIAKVTRDREMEEL
DKAYPQYGFAKHKGYPTKAHFEAIEEHGVISEHRRSFKPVKRVLGIE
>Mature_206_residues
TKKAESKELPPFEYPEGYQLFAGVDEVGRGPLVGAVVTAAVILDPNNPIEGLTDSKKLTDKKRELLFPEIQEKALAWSLG
RCEAHEIDELNILQATMVAMQRAIAGLNITPDFALIDGNKVPELPMAGLAVVKGDLRVQEISAASIIAKVTRDREMEELD
KAYPQYGFAKHKGYPTKAHFEAIEEHGVISEHRRSFKPVKRVLGIE

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=194, Percent_Identity=70.6185567010309, Blast_Score=281, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 22889; Mature: 22757

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKAESKELPPFEYPEGYQLFAGVDEVGRGPLVGAVVTAAVILDPNNPIEGLTDSKKLT
CCCCCCCCCCCCCCCCCCCEEEECHHHHCCCCHHHHHHHHHHEECCCCCCCCCCCCHHHH
DKKRELLFPEIQEKALAWSLGRCEAHEIDELNILQATMVAMQRAIAGLNITPDFALIDGN
HHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
KVPELPMAGLAVVKGDLRVQEISAASIIAKVTRDREMEELDKAYPQYGFAKHKGYPTKAH
CCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHCCCCCCHHH
FEAIEEHGVISEHRRSFKPVKRVLGIE
HHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKKAESKELPPFEYPEGYQLFAGVDEVGRGPLVGAVVTAAVILDPNNPIEGLTDSKKLT
CCCCCCCCCCCCCCCCCCEEEECHHHHCCCCHHHHHHHHHHEECCCCCCCCCCCCHHHH
DKKRELLFPEIQEKALAWSLGRCEAHEIDELNILQATMVAMQRAIAGLNITPDFALIDGN
HHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
KVPELPMAGLAVVKGDLRVQEISAASIIAKVTRDREMEELDKAYPQYGFAKHKGYPTKAH
CCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHCCCCCCHHH
FEAIEEHGVISEHRRSFKPVKRVLGIE
HHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA