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The map label for this gene is flaA [H]

Identifier: 59712473

GI number: 59712473

Start: 2099046

End: 2100185

Strand: Reverse

Name: flaA [H]

Synonym: VF_1866

Alternate gene names: 59712473

Gene position: 2100185-2099046 (Counterclockwise)

Preceding gene: 59712474

Following gene: 59712472

Centisome position: 72.48

GC content: 42.72

Gene sequence:

>1140_bases
ATGGCTGTAAATGTAAATACTAACGTATCTGCGATGACTGCGCAGCGTTACCTAAACAACGCAACAAATGACCTAAACAA
CTCAATGGAGCGTTTATCGTCAGGTACTAAAATCAACAGCGCAAAAGATGACGCTGCTGGTCTACAAATTTCTAACCGCT
TAACAGCTCAGACTCGTGGTCTTGATGTTGCTATGCGTAACGCGAACGATGGTATTTCTATCGCTCAAACAGCTGAAGGT
GCGATGAACGAATCGACTAATATCCTTCAACGTATGCGTGATTTATCACTACAAGCGGCAAATGGTTCAAACTCAGACCA
AGATCGTGCTTCTATCCAAGAAGAAGTTCACGCACTATCTGATGAACTAAACCGTATCGCAGAGACAACATCATTCGGTG
GTCGTCGTCTTCTTAACGGTCAATTCGGTGAGTCAGCATTCCAAATCGGTGCTAACGCTGGTGAAGCAATCCTAATCAAG
TTACCGTCAGTTCGTGCTGATGATGACAGCATGGGTGGCCAACGTTTCGTTTCTGAAAACGGCAAGAGTGCATCTTGGAA
CGTAGAACCTGGTAAGAATGACATGAAACTAGAATTCACTACTAAGAAAGGTGAAGCAGTTTCTATCGATATCAGTGCTA
AAGCTGGTGACGACATCGAAGAATTAGCAACATACATCAACGGTCAATCAGACAAGATCTCAGCATCTGTTGGTGATGAA
GGTAAACTTCAACTGTTTGTTGCTGAACCATCAATCGAAGGTGAGCTATCAATCACTGGTAACCTTGCAACTGAACTTGG
CCTAGAAAGTGGTCTTGGTTCTAAAGCAACGGTTGATAAACTAGACGTAACGTCTGTAGGTGATGCACAAGTGTCTATCG
GTGTTATCGATTCAGCTCTTGCTTACATCGACCGTGAGCGTGCTGATTTAGGTGCTAAACAAAACCGTCTAGGTCACAGC
ATCAACAACTTGTCAAACATTCAAGAGAATGTATCTGCTTCTAACAGCCGAATCAAAGATACTGATTTTGCTAAAGAAAC
AACAAACATGACAAAAGCACAAATCCTTCAGCAGTCTAGTACTTCTATTCTTGCTCAAGCGAAACAGTTACCAAACGCTG
CACTAACTTTACTGCAGTAA

Upstream 100 bases:

>100_bases
TATTGGCTGATTGTGGCTGATTGTGGCTGATATAAATTTAAATATTTCTGAATAGAGCAGAAATGAGTTTTCGTGAAAGC
GAAGCCAAAGGAGAGCAACG

Downstream 100 bases:

>100_bases
TTGAGTAACTAACAACAGTCATATGAATGGACAAGAGGTGCTCTCATCTCTCATCAACCTCTTGTTCACCTGATTGTTGT
GCAAGCTATAGGTAACTGGT

Product: flagellin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MAVNVNTNVSAMTAQRYLNNATNDLNNSMERLSSGTKINSAKDDAAGLQISNRLTAQTRGLDVAMRNANDGISIAQTAEG
AMNESTNILQRMRDLSLQAANGSNSDQDRASIQEEVHALSDELNRIAETTSFGGRRLLNGQFGESAFQIGANAGEAILIK
LPSVRADDDSMGGQRFVSENGKSASWNVEPGKNDMKLEFTTKKGEAVSIDISAKAGDDIEELATYINGQSDKISASVGDE
GKLQLFVAEPSIEGELSITGNLATELGLESGLGSKATVDKLDVTSVGDAQVSIGVIDSALAYIDRERADLGAKQNRLGHS
INNLSNIQENVSASNSRIKDTDFAKETTNMTKAQILQQSSTSILAQAKQLPNAALTLLQ

Sequences:

>Translated_379_residues
MAVNVNTNVSAMTAQRYLNNATNDLNNSMERLSSGTKINSAKDDAAGLQISNRLTAQTRGLDVAMRNANDGISIAQTAEG
AMNESTNILQRMRDLSLQAANGSNSDQDRASIQEEVHALSDELNRIAETTSFGGRRLLNGQFGESAFQIGANAGEAILIK
LPSVRADDDSMGGQRFVSENGKSASWNVEPGKNDMKLEFTTKKGEAVSIDISAKAGDDIEELATYINGQSDKISASVGDE
GKLQLFVAEPSIEGELSITGNLATELGLESGLGSKATVDKLDVTSVGDAQVSIGVIDSALAYIDRERADLGAKQNRLGHS
INNLSNIQENVSASNSRIKDTDFAKETTNMTKAQILQQSSTSILAQAKQLPNAALTLLQ
>Mature_378_residues
AVNVNTNVSAMTAQRYLNNATNDLNNSMERLSSGTKINSAKDDAAGLQISNRLTAQTRGLDVAMRNANDGISIAQTAEGA
MNESTNILQRMRDLSLQAANGSNSDQDRASIQEEVHALSDELNRIAETTSFGGRRLLNGQFGESAFQIGANAGEAILIKL
PSVRADDDSMGGQRFVSENGKSASWNVEPGKNDMKLEFTTKKGEAVSIDISAKAGDDIEELATYINGQSDKISASVGDEG
KLQLFVAEPSIEGELSITGNLATELGLESGLGSKATVDKLDVTSVGDAQVSIGVIDSALAYIDRERADLGAKQNRLGHSI
NNLSNIQENVSASNSRIKDTDFAKETTNMTKAQILQQSSTSILAQAKQLPNAALTLLQ

Specific function: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaA is essential for flagellar synthesis and full motility. Important for virulence at two different levels:is needed for crossing the fish integument and may

COG id: COG1344

COG function: function code N; Flagellin and related hook-associated proteins

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial flagellin family [H]

Homologues:

Organism=Escherichia coli, GI1788232, Length=166, Percent_Identity=47.5903614457831, Blast_Score=142, Evalue=4e-35,

Paralogues:

None

Copy number: 200,000-400,000 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001492
- InterPro:   IPR001029
- InterPro:   IPR010810 [H]

Pfam domain/function: PF00700 Flagellin_C; PF07196 Flagellin_IN; PF00669 Flagellin_N [H]

EC number: NA

Molecular weight: Translated: 40214; Mature: 40083

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVNVNTNVSAMTAQRYLNNATNDLNNSMERLSSGTKINSAKDDAAGLQISNRLTAQTRG
CEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHCC
LDVAMRNANDGISIAQTAEGAMNESTNILQRMRDLSLQAANGSNSDQDRASIQEEVHALS
CEEEEECCCCCCEEHHHHCCCCCHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHHH
DELNRIAETTSFGGRRLLNGQFGESAFQIGANAGEAILIKLPSVRADDDSMGGQRFVSEN
HHHHHHHHHHCCCCCEECCCCCCCHHHEECCCCCCEEEEECCCCCCCCCCCCCHHHHHCC
GKSASWNVEPGKNDMKLEFTTKKGEAVSIDISAKAGDDIEELATYINGQSDKISASVGDE
CCCCEEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCC
GKLQLFVAEPSIEGELSITGNLATELGLESGLGSKATVDKLDVTSVGDAQVSIGVIDSAL
CEEEEEEECCCCCCEEEEECCHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEHHHHHHHH
AYIDRERADLGAKQNRLGHSINNLSNIQENVSASNSRIKDTDFAKETTNMTKAQILQQSS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TSILAQAKQLPNAALTLLQ
HHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
AVNVNTNVSAMTAQRYLNNATNDLNNSMERLSSGTKINSAKDDAAGLQISNRLTAQTRG
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHCC
LDVAMRNANDGISIAQTAEGAMNESTNILQRMRDLSLQAANGSNSDQDRASIQEEVHALS
CEEEEECCCCCCEEHHHHCCCCCHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHHHHH
DELNRIAETTSFGGRRLLNGQFGESAFQIGANAGEAILIKLPSVRADDDSMGGQRFVSEN
HHHHHHHHHHCCCCCEECCCCCCCHHHEECCCCCCEEEEECCCCCCCCCCCCCHHHHHCC
GKSASWNVEPGKNDMKLEFTTKKGEAVSIDISAKAGDDIEELATYINGQSDKISASVGDE
CCCCEEECCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCC
GKLQLFVAEPSIEGELSITGNLATELGLESGLGSKATVDKLDVTSVGDAQVSIGVIDSAL
CEEEEEEECCCCCCEEEEECCHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEHHHHHHHH
AYIDRERADLGAKQNRLGHSINNLSNIQENVSASNSRIKDTDFAKETTNMTKAQILQQSS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TSILAQAKQLPNAALTLLQ
HHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8631707 [H]