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The map label for this gene is fliI [H]

Identifier: 59712456

GI number: 59712456

Start: 2080117

End: 2081436

Strand: Reverse

Name: fliI [H]

Synonym: VF_1849

Alternate gene names: 59712456

Gene position: 2081436-2080117 (Counterclockwise)

Preceding gene: 59712457

Following gene: 59712455

Centisome position: 71.83

GC content: 43.11

Gene sequence:

>1320_bases
ATGTTGCCATTATCTGAACGTTTATCTCAATATAAAACCACAGGCTTAACCACTCGCGCTATTGCCTCAGGTAAATTAGT
GCGTGTTGTTGGTTTAACACTTGAAGCAACAGGTTGTCGAGCGCCTATTGGTAGTTCCTGTTTGGTCGAAACCGTAAATG
GTGAGATTGAAGCCGAAGTTGTTGGCTTTTCTGGTGAAAACTTATTTTTAATGCCAAGTGAACAAGTTTCAGGCGTATTA
CCTGGCGCTAAAGTCACTCCAATCGCCGATGGCAGTGGTATTCCTGTTGGTATGGAACTACTTGGTCGTGTGGTTGATGG
GGTTGGTAATCCTATTGACGGTCTTGGTGAACTTTATACTGAACATACAGCATCATTTACTTCTGAGCCAATTAACCCAT
TATCACGAAAGCCTATTTCAGAGCCGCTTGATGTTGGTTTAAAAGCAATTAACGGCTTATTGACTGTGGGTAAAGGTCAG
CGTTTAGGTTTATTCGCTGGTTCTGGTGTTGGTAAATCGGTAACACTAGGCATGATGACTCGTGGTACAACAGCACAAGT
GGTTGTGGTTGGCTTAATTGGTGAGCGTGGACGTGAAGTTAAAGAGTTCATTGAAGAAATTTTAGGTCCTGAAGGTCGCC
AACGCTCTGTTGTGGTTGCCGCTCCTGCCGATGCATCTGCATTGATGCGATTAAAAGGGTGTCAAACCGCATTAACCATT
GCTGAGTATTTCCGCGATCAAGGCTTAGACGTTTTACTATTAATGGATTCGTTAACACGTTTTGCTCAAGCACAGCGTGA
AATTGCCTTATCTGTTGGTGAGCCACCGGCAACCAAAGGTTATCCGCCTTCTGTATTTGCAAAATTACCGGCATTGGTTG
AACGAGCGGGTAATGGTAATGAAAATCAAGGCTCTATTACGGCGTTCTTTACCGTATTAACCGAAGGGGATGATTTACAA
GATCCTATTGCTGATGCTTCACGTGCGATTTTGGATGGACACATTGTATTGTCTCGTGAAATGGCTGATGCCGGACATTA
CCCTGCTATCGATGTAGAGAAATCAGTCAGTCGTGTTATGCCACAAATCACCGACGAAGAACATATGCTTATGTCTAAAG
CGGTGAGACAAGTGTTGTCTACTTGCCGTAAAAACCAAGACTTGGTGTCGATTGGGGCGTATAAACCGGGTACTGATCCT
GCTATTGATCAAGCGTTTACGTTAAAACCAAGATTAGACGAATATTTACAGCAGCGTATGAAAGAAAGTGTTCCATACGA
TATGTGTAAAAACATGCTTAAAATGTTGCTTAGTGGCTAA

Upstream 100 bases:

>100_bases
TTCAAGCTTCTGATTCAAAAGTGAGTTATTTGCTAGAAGAACGAATTAAGAGCGTACTGAACAAATTCTGTGGTGTGAAC
CGTCATCAAGGAAATCAGTA

Downstream 100 bases:

>100_bases
GGCATAATAAATGACAAGTACTTTTGATTTCTTATTAGAGCAAGCCCAAGAAAGAGAAAACCAAGCGGTGATGGCGCTGA
ACAAAGCCAAAGCTGAATTG

Product: flagellum-specific ATP synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MLPLSERLSQYKTTGLTTRAIASGKLVRVVGLTLEATGCRAPIGSSCLVETVNGEIEAEVVGFSGENLFLMPSEQVSGVL
PGAKVTPIADGSGIPVGMELLGRVVDGVGNPIDGLGELYTEHTASFTSEPINPLSRKPISEPLDVGLKAINGLLTVGKGQ
RLGLFAGSGVGKSVTLGMMTRGTTAQVVVVGLIGERGREVKEFIEEILGPEGRQRSVVVAAPADASALMRLKGCQTALTI
AEYFRDQGLDVLLLMDSLTRFAQAQREIALSVGEPPATKGYPPSVFAKLPALVERAGNGNENQGSITAFFTVLTEGDDLQ
DPIADASRAILDGHIVLSREMADAGHYPAIDVEKSVSRVMPQITDEEHMLMSKAVRQVLSTCRKNQDLVSIGAYKPGTDP
AIDQAFTLKPRLDEYLQQRMKESVPYDMCKNMLKMLLSG

Sequences:

>Translated_439_residues
MLPLSERLSQYKTTGLTTRAIASGKLVRVVGLTLEATGCRAPIGSSCLVETVNGEIEAEVVGFSGENLFLMPSEQVSGVL
PGAKVTPIADGSGIPVGMELLGRVVDGVGNPIDGLGELYTEHTASFTSEPINPLSRKPISEPLDVGLKAINGLLTVGKGQ
RLGLFAGSGVGKSVTLGMMTRGTTAQVVVVGLIGERGREVKEFIEEILGPEGRQRSVVVAAPADASALMRLKGCQTALTI
AEYFRDQGLDVLLLMDSLTRFAQAQREIALSVGEPPATKGYPPSVFAKLPALVERAGNGNENQGSITAFFTVLTEGDDLQ
DPIADASRAILDGHIVLSREMADAGHYPAIDVEKSVSRVMPQITDEEHMLMSKAVRQVLSTCRKNQDLVSIGAYKPGTDP
AIDQAFTLKPRLDEYLQQRMKESVPYDMCKNMLKMLLSG
>Mature_439_residues
MLPLSERLSQYKTTGLTTRAIASGKLVRVVGLTLEATGCRAPIGSSCLVETVNGEIEAEVVGFSGENLFLMPSEQVSGVL
PGAKVTPIADGSGIPVGMELLGRVVDGVGNPIDGLGELYTEHTASFTSEPINPLSRKPISEPLDVGLKAINGLLTVGKGQ
RLGLFAGSGVGKSVTLGMMTRGTTAQVVVVGLIGERGREVKEFIEEILGPEGRQRSVVVAAPADASALMRLKGCQTALTI
AEYFRDQGLDVLLLMDSLTRFAQAQREIALSVGEPPATKGYPPSVFAKLPALVERAGNGNENQGSITAFFTVLTEGDDLQ
DPIADASRAILDGHIVLSREMADAGHYPAIDVEKSVSRVMPQITDEEHMLMSKAVRQVLSTCRKNQDLVSIGAYKPGTDP
AIDQAFTLKPRLDEYLQQRMKESVPYDMCKNMLKMLLSG

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=384, Percent_Identity=31.25, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI50345984, Length=341, Percent_Identity=28.7390029325513, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4757810, Length=341, Percent_Identity=28.7390029325513, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI19913424, Length=245, Percent_Identity=30.2040816326531, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19913428, Length=285, Percent_Identity=28.4210526315789, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI19913426, Length=282, Percent_Identity=27.3049645390071, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1788251, Length=425, Percent_Identity=60, Blast_Score=495, Evalue=1e-141,
Organism=Escherichia coli, GI1790170, Length=302, Percent_Identity=32.4503311258278, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790172, Length=361, Percent_Identity=27.4238227146814, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25144756, Length=395, Percent_Identity=31.3924050632911, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71988080, Length=341, Percent_Identity=28.4457478005865, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71988063, Length=341, Percent_Identity=28.4457478005865, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17510931, Length=301, Percent_Identity=27.906976744186, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17565854, Length=270, Percent_Identity=31.1111111111111, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=293, Percent_Identity=27.6450511945392, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988074, Length=327, Percent_Identity=26.605504587156, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=383, Percent_Identity=30.2872062663185, Blast_Score=159, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6319370, Length=343, Percent_Identity=30.6122448979592, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6319603, Length=282, Percent_Identity=28.7234042553192, Blast_Score=123, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6320016, Length=259, Percent_Identity=30.1158301158301, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24638766, Length=406, Percent_Identity=31.5270935960591, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI28574560, Length=318, Percent_Identity=35.2201257861635, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24658560, Length=341, Percent_Identity=29.9120234604106, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24583988, Length=250, Percent_Identity=30, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24583986, Length=250, Percent_Identity=30, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24583984, Length=250, Percent_Identity=30, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24583992, Length=321, Percent_Identity=28.3489096573209, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281361666, Length=287, Percent_Identity=28.9198606271777, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646341, Length=287, Percent_Identity=28.9198606271777, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136796, Length=287, Percent_Identity=28.9198606271777, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI20129479, Length=237, Percent_Identity=27.8481012658228, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005714
- InterPro:   IPR020005 [H]

Pfam domain/function: PF00006 ATP-synt_ab [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 46752; Mature: 46752

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLSERLSQYKTTGLTTRAIASGKLVRVVGLTLEATGCRAPIGSSCLVETVNGEIEAEV
CCCHHHHHHHHHHCCCCHHHHCCCCEEEEEEEEEEECCCCCCCCCCCEEEECCCCEEEEE
VGFSGENLFLMPSEQVSGVLPGAKVTPIADGSGIPVGMELLGRVVDGVGNPIDGLGELYT
EEECCCEEEEECCHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
EHTASFTSEPINPLSRKPISEPLDVGLKAINGLLTVGKGQRLGLFAGSGVGKSVTLGMMT
HHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHEEECCCCEEEEEECCCCCCEEEEEEEE
RGTTAQVVVVGLIGERGREVKEFIEEILGPEGRQRSVVVAAPADASALMRLKGCQTALTI
CCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
AEYFRDQGLDVLLLMDSLTRFAQAQREIALSVGEPPATKGYPPSVFAKLPALVERAGNGN
HHHHHHCCCEEEHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC
ENQGSITAFFTVLTEGDDLQDPIADASRAILDGHIVLSREMADAGHYPAIDVEKSVSRVM
CCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCEEEEEEHHHCCCCCCCCCHHHHHHHHC
PQITDEEHMLMSKAVRQVLSTCRKNQDLVSIGAYKPGTDPAIDQAFTLKPRLDEYLQQRM
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHH
KESVPYDMCKNMLKMLLSG
HHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPLSERLSQYKTTGLTTRAIASGKLVRVVGLTLEATGCRAPIGSSCLVETVNGEIEAEV
CCCHHHHHHHHHHCCCCHHHHCCCCEEEEEEEEEEECCCCCCCCCCCEEEECCCCEEEEE
VGFSGENLFLMPSEQVSGVLPGAKVTPIADGSGIPVGMELLGRVVDGVGNPIDGLGELYT
EEECCCEEEEECCHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
EHTASFTSEPINPLSRKPISEPLDVGLKAINGLLTVGKGQRLGLFAGSGVGKSVTLGMMT
HHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHEEECCCCEEEEEECCCCCCEEEEEEEE
RGTTAQVVVVGLIGERGREVKEFIEEILGPEGRQRSVVVAAPADASALMRLKGCQTALTI
CCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
AEYFRDQGLDVLLLMDSLTRFAQAQREIALSVGEPPATKGYPPSVFAKLPALVERAGNGN
HHHHHHCCCEEEHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCC
ENQGSITAFFTVLTEGDDLQDPIADASRAILDGHIVLSREMADAGHYPAIDVEKSVSRVM
CCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCEEEEEEHHHCCCCCCCCCHHHHHHHHC
PQITDEEHMLMSKAVRQVLSTCRKNQDLVSIGAYKPGTDPAIDQAFTLKPRLDEYLQQRM
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHH
KESVPYDMCKNMLKMLLSG
HHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]