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The map label for this gene is flhA [H]

Identifier: 59712444

GI number: 59712444

Start: 2069627

End: 2071720

Strand: Reverse

Name: flhA [H]

Synonym: VF_1837

Alternate gene names: 59712444

Gene position: 2071720-2069627 (Counterclockwise)

Preceding gene: 59712446

Following gene: 59712443

Centisome position: 71.5

GC content: 41.79

Gene sequence:

>2094_bases
ATGAAATTTCCAATTCCGCTGCCAAATAAATTATCAGCTCTACAGGGGCGAGGTATACCACCAATCGGTGTACCTGTATT
AGTGTTGTCCACACTGGCAATGGTAATTTTACCCATACCGGCCTTCTTACTCGATTTAATGTTTACCTTTAACATTGCCT
TAGCCATGGTGGTGTTACTTGTGACTATCTATACCCGCCGACCTCTGGATTTTGCAGCGTTTCCGACGATACTTCTGGTA
TCAACACTATTACGTCTTGCTTTGAACGTTGCTTCAACACGAGTGGTTCTTTTACATGGTCATGAAGGGCCTGGTGCCGC
AGGTCACGTTATCGATGCTTTTGGTAATGTGGTTATCGGTGGTAACTATGCGGTTGGTTTAATTGTATTCATTATCCTAA
TGATCATTAACTTCATGGTTGTAACCAAAGGTGCGGGTCGTATTTCTGAAGTCAGTGCTCGTTTTACCTTGGATGCATTA
CCAGGTAAACAAATGGCGATCGATGCCGATTTAAACGCAGGCTTGATTGACCAAGATCAAGCACGTATTCGTCGTTTTGA
AGTGACAAAAGAAGCGGACTTTTATGGTTCAATGGACGGTGCTTCTAAATTCGTAAAAGGGGATGCCATCGCCGGTATTC
TTATTCTATTTATTAACATCATTGGTGGCCTTGCCATAGGTATGGCGCAATTCAATCTTGGCTTTGGTGAAGCGATTCAA
ATCTACACATTGCTAACGATTGGTGATGGCTTGGTTGCTCAAATTCCATCACTTCTTTTATCGATTGGTGCCGCTATTAT
GGTTACTCGCCAAAACACCGATGAAGATATGGGTGAACAACTGGTTTTCCAATTAGTTGATAATCCCAAAGCATTAATGG
TAACAGCAGGTATCATGTTTGTTATGGGTATCGTTCCTGGTATGCCCCATTTTCCATTCATCTTATTGGCATTATTAGCG
GGTGGTTGGTCGTATTATTTAACCAAGAAAAAAGAGCAAGAAAGCGAAGAGCAGAAAGCTGCACCACCAATGGAACTGTC
GGCTTCACAACCAAAAGAATTATCATGGGATGACGTTCAACCTGTTGATGTTATTGGTTTAGAAGTGGGTTACCGCTTGA
TCCCTATGGTAGATAAAGAGCAAGGTGGTGAATTACTTGATCGTGTGAAAGGGGTTCGTAAGAAGCTATCTCAAGATTTT
GGCTTCTTAGTACCTGCTGTACATATTCGAGATAACTTAGAATTACCGCCAAACGTATATCGTATTACTCTAATGGGCGT
AGCTGGTGGTGAAGCAGAAATTCGTCCTGATAAAGAATTGGCTATCAATCCAGGTCAGGTTTATGGTTCGATTGAAGGTG
AACCAACATTTGATCCAGCGTTTGGATTAGAAGCGGTTTGGATTAATGAAGAGCAAAGAGAGCACGCTCAAGCATTAGGC
TATACTGTAGTAGATGCAGCAACAGTACTGGCAACGCACTTAAGTCAGTTATTAACAAATAATGCAGCTCAGCTGTTAGG
TCACGAAGAAGTTCAGAACTTACTTGAGTTGTTGGCGCAGAGCTCACCTAAGTTAGTTGAGGGTCTGGTTCCTGATCAAT
TACCTCTGGGTGCGGTTGTAAAAGTGCTTCAGAATTTATTGAATGAAGCAATTCCAATTCGTGATATTCGAACCATTGTC
CAAACTTTGTCTGAATATGCGCCAAAAAGTCAAGAACCTGACATTTTGACGGCGGCTGTTCGAATTTCATTAAAACGATT
AATTGTTCAGGAAATCAATGGGATAGAGGCTGAAATGCCAGTTATTACTCTGATTCCTGAATTGGAACAAATCTTGCATC
AAACTATGCAGGCATCTGGTGGTGAGACCACTGGTATTGAGCCAGGGTTAGCAGAACGTCTGCAAGCATCATTAACTCAA
GCGACTCAAGAGCAAGAGTTAAAAGGCGAAGCAGCTGTGCTGTTAACATCAGGGGTATTACGTTCGACATTAGCTAAGTT
TGTGAAGAATACGATTCCAAACTTACGAGTTCTCTCTTACCAAGAGATCCCTGATGAGAAACAAATTAGAATTGTTCAAG
CTGTTGGTAACTAA

Upstream 100 bases:

>100_bases
TAATCTGGCTCGAAATTTGCTTTAGTAGCAAAGTAATTACGCTATTAGTCACTTAATATTTATTTCGTAAGAAATACGAG
TTTAGAAGAAGTAGAAGTTA

Downstream 100 bases:

>100_bases
CCGCGTCAACTTATTTAACGCAGGAATACGATATTGAAAATTAAACGATTTTTTGCAAAAGACATGCGCTCTGCTCTGGT
TCAGGTAAAAGAAGAGCTAG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MKFPIPLPNKLSALQGRGIPPIGVPVLVLSTLAMVILPIPAFLLDLMFTFNIALAMVVLLVTIYTRRPLDFAAFPTILLV
STLLRLALNVASTRVVLLHGHEGPGAAGHVIDAFGNVVIGGNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQDQARIRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLAIGMAQFNLGFGEAIQ
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTAGIMFVMGIVPGMPHFPFILLALLA
GGWSYYLTKKKEQESEEQKAAPPMELSASQPKELSWDDVQPVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDF
GFLVPAVHIRDNLELPPNVYRITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTFDPAFGLEAVWINEEQREHAQALG
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLAQSSPKLVEGLVPDQLPLGAVVKVLQNLLNEAIPIRDIRTIV
QTLSEYAPKSQEPDILTAAVRISLKRLIVQEINGIEAEMPVITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTQ
ATQEQELKGEAAVLLTSGVLRSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN

Sequences:

>Translated_697_residues
MKFPIPLPNKLSALQGRGIPPIGVPVLVLSTLAMVILPIPAFLLDLMFTFNIALAMVVLLVTIYTRRPLDFAAFPTILLV
STLLRLALNVASTRVVLLHGHEGPGAAGHVIDAFGNVVIGGNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQDQARIRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLAIGMAQFNLGFGEAIQ
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTAGIMFVMGIVPGMPHFPFILLALLA
GGWSYYLTKKKEQESEEQKAAPPMELSASQPKELSWDDVQPVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDF
GFLVPAVHIRDNLELPPNVYRITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTFDPAFGLEAVWINEEQREHAQALG
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLAQSSPKLVEGLVPDQLPLGAVVKVLQNLLNEAIPIRDIRTIV
QTLSEYAPKSQEPDILTAAVRISLKRLIVQEINGIEAEMPVITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTQ
ATQEQELKGEAAVLLTSGVLRSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN
>Mature_697_residues
MKFPIPLPNKLSALQGRGIPPIGVPVLVLSTLAMVILPIPAFLLDLMFTFNIALAMVVLLVTIYTRRPLDFAAFPTILLV
STLLRLALNVASTRVVLLHGHEGPGAAGHVIDAFGNVVIGGNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQDQARIRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLAIGMAQFNLGFGEAIQ
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTAGIMFVMGIVPGMPHFPFILLALLA
GGWSYYLTKKKEQESEEQKAAPPMELSASQPKELSWDDVQPVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDF
GFLVPAVHIRDNLELPPNVYRITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTFDPAFGLEAVWINEEQREHAQALG
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLAQSSPKLVEGLVPDQLPLGAVVKVLQNLLNEAIPIRDIRTIV
QTLSEYAPKSQEPDILTAAVRISLKRLIVQEINGIEAEMPVITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTQ
ATQEQELKGEAAVLLTSGVLRSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=673, Percent_Identity=53.6404160475483, Blast_Score=702, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75415; Mature: 75415

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPIPLPNKLSALQGRGIPPIGVPVLVLSTLAMVILPIPAFLLDLMFTFNIALAMVVLL
CCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTIYTRRPLDFAAFPTILLVSTLLRLALNVASTRVVLLHGHEGPGAAGHVIDAFGNVVIG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCEEEC
GNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDALPGKQMAIDADLNAGLIDQDQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHH
ARIRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLAIGMAQFNLGFGEAIQ
HHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTAGIMF
EEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
VMGIVPGMPHFPFILLALLAGGWSYYLTKKKEQESEEQKAAPPMELSASQPKELSWDDVQ
HHHHCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDFGFLVPAVHIRDNLELPPNVY
CHHEEEHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEE
RITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTFDPAFGLEAVWINEEQREHAQALG
EEEEEEECCCCCCCCCCCCEECCCCCEEECCCCCCCCCCCCCCEEEEECHHHHHHHHHHC
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLAQSSPKLVEGLVPDQLPLGAVV
HHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHH
KVLQNLLNEAIPIRDIRTIVQTLSEYAPKSQEPDILTAAVRISLKRLIVQEINGIEAEMP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
VITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTQATQEQELKGEAAVLLTSGVL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN
HHHHHHHHHHCCCCCEEEEHHCCCCHHHEEEEEECCC
>Mature Secondary Structure
MKFPIPLPNKLSALQGRGIPPIGVPVLVLSTLAMVILPIPAFLLDLMFTFNIALAMVVLL
CCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTIYTRRPLDFAAFPTILLVSTLLRLALNVASTRVVLLHGHEGPGAAGHVIDAFGNVVIG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCEEEC
GNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDALPGKQMAIDADLNAGLIDQDQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHH
ARIRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLAIGMAQFNLGFGEAIQ
HHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTAGIMF
EEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
VMGIVPGMPHFPFILLALLAGGWSYYLTKKKEQESEEQKAAPPMELSASQPKELSWDDVQ
HHHHCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDFGFLVPAVHIRDNLELPPNVY
CHHEEEHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEE
RITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTFDPAFGLEAVWINEEQREHAQALG
EEEEEEECCCCCCCCCCCCEECCCCCEEECCCCCCCCCCCCCCEEEEECHHHHHHHHHHC
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLAQSSPKLVEGLVPDQLPLGAVV
HHHHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHH
KVLQNLLNEAIPIRDIRTIVQTLSEYAPKSQEPDILTAAVRISLKRLIVQEINGIEAEMP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
VITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTQATQEQELKGEAAVLLTSGVL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
RSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN
HHHHHHHHHHCCCCCEEEEHHCCCCHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]