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The map label for this gene is ccmB [H]

Identifier: 59712430

GI number: 59712430

Start: 2057595

End: 2058263

Strand: Reverse

Name: ccmB [H]

Synonym: VF_1823

Alternate gene names: 59712430

Gene position: 2058263-2057595 (Counterclockwise)

Preceding gene: 59712431

Following gene: 59712429

Centisome position: 71.03

GC content: 38.27

Gene sequence:

>669_bases
ATGTTAACATCAATGACAACTGTTATTCGACGTGAGCTTTTGATTGCCTTTCGTCGTAAAGCCGATATTTTGAATCCATT
ATGGTTCTTTATTATCGTTATTACGCTATTTCCATTAAGTATTGGCCCTGAGCCAAATTTGTTAGCACGTATTGCAGCAG
GTATTGTTTGGGTTGCTGCATTATTATCAGCATTACTTTCATTAGAGCGTCTATTCCGAGATGATTTCTCTGATGGTTCA
CTAGAACAAATGATGTTAATGCCAACACCTCTTTCAGTATTAGTGTTAGCCAAAGTGGTTGCTCACTGGCTATTAACTGG
GCTGCCTTTAATTATTATTAGTCCATTACTCGCTATTTTGCTCTCTTTGGATTTTAATACTTGGCTAGCGATTGTACTAA
CATTATTGTTGGGCACGCCGACATTGAGTTTTCTTGGTGGTGTTGGAGTAGCATTAACCGTAGGTTTACAAAAAGGAGGG
GTATTATTAAGTTTATTGATCCTTCCTCTGTATATTCCCGTTTTAATTTTTGCAACATCAGCAATAGATGCTGCAAGTTT
AGGTATGGCTTATAATGGCCAGTTAGCGATTTTAGGGGCCTTATTAATGGGCTCTGCAACATTGACTCCGTTTGCTATTA
GTTCGGCATTACGAGTCAGTGTGCAATAA

Upstream 100 bases:

>100_bases
TATGGATCATGCAAAACAAGGTGGAATTGTGTTATTAACGACTCACCAAGATTTATTCATTGATAGTAATGAACTTAAAA
AAATTAGGTTAGGTGAGTAA

Downstream 100 bases:

>100_bases
CATAATTATAATTTTTATATTTGAAAGTAAGTGAGATAAACCAATGTGGAAATGGCTACATCCTTACGCTAAACCAGAAA
AAGCGTATCAACTAAGTACC

Product: heme exporter subunit B

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MLTSMTTVIRRELLIAFRRKADILNPLWFFIIVITLFPLSIGPEPNLLARIAAGIVWVAALLSALLSLERLFRDDFSDGS
LEQMMLMPTPLSVLVLAKVVAHWLLTGLPLIIISPLLAILLSLDFNTWLAIVLTLLLGTPTLSFLGGVGVALTVGLQKGG
VLLSLLILPLYIPVLIFATSAIDAASLGMAYNGQLAILGALLMGSATLTPFAISSALRVSVQ

Sequences:

>Translated_222_residues
MLTSMTTVIRRELLIAFRRKADILNPLWFFIIVITLFPLSIGPEPNLLARIAAGIVWVAALLSALLSLERLFRDDFSDGS
LEQMMLMPTPLSVLVLAKVVAHWLLTGLPLIIISPLLAILLSLDFNTWLAIVLTLLLGTPTLSFLGGVGVALTVGLQKGG
VLLSLLILPLYIPVLIFATSAIDAASLGMAYNGQLAILGALLMGSATLTPFAISSALRVSVQ
>Mature_222_residues
MLTSMTTVIRRELLIAFRRKADILNPLWFFIIVITLFPLSIGPEPNLLARIAAGIVWVAALLSALLSLERLFRDDFSDGS
LEQMMLMPTPLSVLVLAKVVAHWLLTGLPLIIISPLLAILLSLDFNTWLAIVLTLLLGTPTLSFLGGVGVALTVGLQKGG
VLLSLLILPLYIPVLIFATSAIDAASLGMAYNGQLAILGALLMGSATLTPFAISSALRVSVQ

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=215, Percent_Identity=69.7674418604651, Blast_Score=243, Evalue=6e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23712; Mature: 23712

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSMTTVIRRELLIAFRRKADILNPLWFFIIVITLFPLSIGPEPNLLARIAAGIVWVAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLSALLSLERLFRDDFSDGSLEQMMLMPTPLSVLVLAKVVAHWLLTGLPLIIISPLLAIL
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LSLDFNTWLAIVLTLLLGTPTLSFLGGVGVALTVGLQKGGVLLSLLILPLYIPVLIFATS
HHCCHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIDAASLGMAYNGQLAILGALLMGSATLTPFAISSALRVSVQ
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLTSMTTVIRRELLIAFRRKADILNPLWFFIIVITLFPLSIGPEPNLLARIAAGIVWVAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLSALLSLERLFRDDFSDGSLEQMMLMPTPLSVLVLAKVVAHWLLTGLPLIIISPLLAIL
HHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LSLDFNTWLAIVLTLLLGTPTLSFLGGVGVALTVGLQKGGVLLSLLILPLYIPVLIFATS
HHCCHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIDAASLGMAYNGQLAILGALLMGSATLTPFAISSALRVSVQ
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]