BacMap

Definition	Vibrio fischeri ES114 chromosome I, complete genome.
Accession	NC_006840
Length	2,897,536

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The map label for this gene is ccmA

Identifier: 59712431

GI number: 59712431

Start: 2058264

End: 2058878

Strand: Reverse

Name: ccmA

Synonym: VF_1824

Alternate gene names: 59712431

Gene position: 2058878-2058264 (Counterclockwise)

Preceding gene: 59712432

Following gene: 59712430

Centisome position: 71.06

GC content: 38.37

Gene sequence:

>615_bases
ATGTTAGAAATCCGCAACGTAACCTGTATCCGTGATGAACGTGTTTTGTTTGAGCGTTTAAACTTTACTATCTCTGATGG
TGAGCTAATTCAGATAGAAGGACAAAATGGTGCGGGTAAAACAACCTTACTCCGAATTATTGCTGGGCTAGGATATGCTG
ATGAAGGCGATATTTTTTGGAAAAATGAATCAATAAAACAGAATCGTGAAGAGTTTCATTCTGACTTACTGTTTCTTGGA
CATCATACTGGTGTTAAACGAGAGCTAACGGCGTTTGAGAATTTAGCCTTTTATCAATCAATGCATGATAACTATAACGA
AGCTGCAATATGGGATGCACTCGCTCGCGTTGGGTTAGCGGGTAGAGAAGATGTAGCCGCTGGACAATTATCTGCAGGAC
AACAGAGACGAGTTGCTTTAGCGCGTCTTTGGTTAAGTAATCATAAATTATGGATACTGGATGAGCCTTTAACTGCGATT
GATAAGCAAGGTGTAAAGGTGCTCGAAAAGTTATTTATGGATCATGCAAAACAAGGTGGAATTGTGTTATTAACGACTCA
CCAAGATTTATTCATTGATAGTAATGAACTTAAAAAAATTAGGTTAGGTGAGTAA

Upstream 100 bases:

>100_bases
TTTATTTACTTATCTATCCAATTAGATTTGTTTAATATCTAAGTTTCCCATTTTTTGCTGTGCTAGAATGCTTTCAATAT
TTTCCAATAAATAGAAGTCT

Downstream 100 bases:

>100_bases
ATGTTAACATCAATGACAACTGTTATTCGACGTGAGCTTTTGATTGCCTTTCGTCGTAAAGCCGATATTTTGAATCCATT
ATGGTTCTTTATTATCGTTA

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLEIRNVTCIRDERVLFERLNFTISDGELIQIEGQNGAGKTTLLRIIAGLGYADEGDIFWKNESIKQNREEFHSDLLFLG
HHTGVKRELTAFENLAFYQSMHDNYNEAAIWDALARVGLAGREDVAAGQLSAGQQRRVALARLWLSNHKLWILDEPLTAI
DKQGVKVLEKLFMDHAKQGGIVLLTTHQDLFIDSNELKKIRLGE

Sequences:

>Translated_204_residues
MLEIRNVTCIRDERVLFERLNFTISDGELIQIEGQNGAGKTTLLRIIAGLGYADEGDIFWKNESIKQNREEFHSDLLFLG
HHTGVKRELTAFENLAFYQSMHDNYNEAAIWDALARVGLAGREDVAAGQLSAGQQRRVALARLWLSNHKLWILDEPLTAI
DKQGVKVLEKLFMDHAKQGGIVLLTTHQDLFIDSNELKKIRLGE
>Mature_204_residues
MLEIRNVTCIRDERVLFERLNFTISDGELIQIEGQNGAGKTTLLRIIAGLGYADEGDIFWKNESIKQNREEFHSDLLFLG
HHTGVKRELTAFENLAFYQSMHDNYNEAAIWDALARVGLAGREDVAAGQLSAGQQRRVALARLWLSNHKLWILDEPLTAI
DKQGVKVLEKLFMDHAKQGGIVLLTTHQDLFIDSNELKKIRLGE

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI105990541, Length=179, Percent_Identity=27.9329608938547, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI21536376, Length=193, Percent_Identity=26.9430051813472, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI150417984, Length=193, Percent_Identity=28.4974093264249, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI45446740, Length=196, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI47078218, Length=196, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI27881501, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI30795238, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI116734710, Length=194, Percent_Identity=25.7731958762887, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI153792144, Length=181, Percent_Identity=27.0718232044199, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI42741659, Length=200, Percent_Identity=25.5, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI87082064, Length=204, Percent_Identity=52.4509803921569, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI87081709, Length=163, Percent_Identity=34.3558282208589, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787370, Length=188, Percent_Identity=32.9787234042553, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1787029, Length=203, Percent_Identity=30.0492610837438, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788761, Length=179, Percent_Identity=32.4022346368715, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789672, Length=181, Percent_Identity=29.8342541436464, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081791, Length=168, Percent_Identity=32.7380952380952, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87081834, Length=184, Percent_Identity=27.1739130434783, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786563, Length=199, Percent_Identity=31.6582914572864, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789586, Length=200, Percent_Identity=28, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789991, Length=211, Percent_Identity=26.0663507109005, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788225, Length=208, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787712, Length=165, Percent_Identity=29.6969696969697, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081782, Length=170, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786703, Length=181, Percent_Identity=30.3867403314917, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786698, Length=192, Percent_Identity=26.0416666666667, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790467, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789873, Length=200, Percent_Identity=27, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1786398, Length=200, Percent_Identity=25, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1788053, Length=172, Percent_Identity=32.5581395348837, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI48994943, Length=191, Percent_Identity=25.6544502617801, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786872, Length=162, Percent_Identity=27.1604938271605, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789593, Length=193, Percent_Identity=25.9067357512953, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787105, Length=215, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787041, Length=195, Percent_Identity=27.1794871794872, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082267, Length=171, Percent_Identity=29.8245614035088, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1787164, Length=183, Percent_Identity=30.6010928961749, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI2367384, Length=219, Percent_Identity=27.3972602739726, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI87082268, Length=141, Percent_Identity=31.2056737588652, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=172, Percent_Identity=27.906976744186, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17559834, Length=182, Percent_Identity=31.3186813186813, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=176, Percent_Identity=24.4318181818182, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666092, Length=190, Percent_Identity=25.7894736842105, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI19920532, Length=176, Percent_Identity=30.6818181818182, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580930, Length=176, Percent_Identity=30.6818181818182, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574150, Length=180, Percent_Identity=28.3333333333333, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007328, Length=180, Percent_Identity=28.3333333333333, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28574744, Length=185, Percent_Identity=29.1891891891892, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648314, Length=190, Percent_Identity=24.2105263157895, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641342, Length=187, Percent_Identity=31.0160427807487, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCMA_VIBF1 (Q5E3S7)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205207.1
- ProteinModelPortal:   Q5E3S7
- SMR:   Q5E3S7
- STRING:   Q5E3S7
- GeneID:   3279066
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_1824
- NMPDR:   fig|312309.3.peg.1823
- eggNOG:   COG4133
- HOGENOM:   HBG758042
- OMA:   VRRPIWL
- PhylomeDB:   Q5E3S7
- ProtClustDB:   PRK13538
- BioCyc:   VFIS312309:VF1824-MONOMER
- HAMAP:   MF_01707
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593
- PANTHER:   PTHR19222:SF5
- SMART:   SM00382
- TIGRFAMs:   TIGR01189

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.41

Molecular weight: Translated: 23141; Mature: 23141

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51243 CCMA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIRNVTCIRDERVLFERLNFTISDGELIQIEGQNGAGKTTLLRIIAGLGYADEGDIFW
CCEECCEEEEHHHHHHHHHHCEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEE
KNESIKQNREEFHSDLLFLGHHTGVKRELTAFENLAFYQSMHDNYNEAAIWDALARVGLA
CCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GREDVAAGQLSAGQQRRVALARLWLSNHKLWILDEPLTAIDKQGVKVLEKLFMDHAKQGG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCC
IVLLTTHQDLFIDSNELKKIRLGE
EEEEEECCCEEECCCCCCEEECCC
>Mature Secondary Structure
MLEIRNVTCIRDERVLFERLNFTISDGELIQIEGQNGAGKTTLLRIIAGLGYADEGDIFW
CCEECCEEEEHHHHHHHHHHCEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEE
KNESIKQNREEFHSDLLFLGHHTGVKRELTAFENLAFYQSMHDNYNEAAIWDALARVGLA
CCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
GREDVAAGQLSAGQQRRVALARLWLSNHKLWILDEPLTAIDKQGVKVLEKLFMDHAKQGG
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCC
IVLLTTHQDLFIDSNELKKIRLGE
EEEEEECCCEEECCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA