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The map label for this gene is ccmG [H]

Identifier: 59712425

GI number: 59712425

Start: 2053577

End: 2054128

Strand: Reverse

Name: ccmG [H]

Synonym: VF_1818

Alternate gene names: 59712425

Gene position: 2054128-2053577 (Counterclockwise)

Preceding gene: 59712426

Following gene: 59712424

Centisome position: 70.89

GC content: 40.4

Gene sequence:

>552_bases
ATGAATAAGAACTTTTTATTTGCACCATTAGCGCTGTTTTTAATTTTAGTCGCTGTGTTTGCTACCCAGTTAACACGCAA
CTCAAATGGTGATGATCCAACTAAACTTGAATCGGTACTGGTAGGTAAACCAGTACCTGAATTCCGCTTAGAAGATCTTG
CTCAAGAAGGAAAGCTTTATGATCAAAGCATCTTTAAAGGCGAGCCTTTACTGCTAAATGTATGGGCTACATGGTGTCCA
ACGTGTTATGCAGAACACCAGTATTTAAATACGCTAGCAACAGAAGGCGTAAAAATCATCGGTATGAACTACAAAGATGA
CCGTGCAGGTGCTGTGCAATGGCTAAAAGAGCTAGGTAATCCGTACCTTATTACTCTTTTTGATGGTGATGGTATGTTAG
GGATGGATCTAGGTGTGTATGGTGCTCCAGAGACTTTCTTAATTGATAGCAATGGCATTGTTCGCTACCGTCATGTTGGT
GATGTTAATGAGCGTAATTGGAATGAAACACTAAAACCAATGTACGACCAACTTGTTGCGGAGGCGAAATAA

Upstream 100 bases:

>100_bases
CTGGGCTGGTTCATTGTTTATGGCATTTGGTGGTGCATTAGCTATGTCTGATAAACGCTATCGTTTCCGTAAAAATGCTA
AAAAACAGGAAGCTTAATTT

Downstream 100 bases:

>100_bases
TGAAATTAAACCTACGTAAATTAGGTCTTCGCAGTTTTGCAGTGATTGCATTTAGTTTATTTGCAGTGCAAGTAAGCTAC
GCAACGATTGACTTATATGA

Product: periplasmic thioredoxin of cytochrome c-type biogenesis

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MNKNFLFAPLALFLILVAVFATQLTRNSNGDDPTKLESVLVGKPVPEFRLEDLAQEGKLYDQSIFKGEPLLLNVWATWCP
TCYAEHQYLNTLATEGVKIIGMNYKDDRAGAVQWLKELGNPYLITLFDGDGMLGMDLGVYGAPETFLIDSNGIVRYRHVG
DVNERNWNETLKPMYDQLVAEAK

Sequences:

>Translated_183_residues
MNKNFLFAPLALFLILVAVFATQLTRNSNGDDPTKLESVLVGKPVPEFRLEDLAQEGKLYDQSIFKGEPLLLNVWATWCP
TCYAEHQYLNTLATEGVKIIGMNYKDDRAGAVQWLKELGNPYLITLFDGDGMLGMDLGVYGAPETFLIDSNGIVRYRHVG
DVNERNWNETLKPMYDQLVAEAK
>Mature_183_residues
MNKNFLFAPLALFLILVAVFATQLTRNSNGDDPTKLESVLVGKPVPEFRLEDLAQEGKLYDQSIFKGEPLLLNVWATWCP
TCYAEHQYLNTLATEGVKIIGMNYKDDRAGAVQWLKELGNPYLITLFDGDGMLGMDLGVYGAPETFLIDSNGIVRYRHVG
DVNERNWNETLKPMYDQLVAEAK

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=183, Percent_Identity=61.7486338797814, Blast_Score=256, Evalue=8e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 20593; Mature: 20593

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNFLFAPLALFLILVAVFATQLTRNSNGDDPTKLESVLVGKPVPEFRLEDLAQEGKLY
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHH
DQSIFKGEPLLLNVWATWCPTCYAEHQYLNTLATEGVKIIGMNYKDDRAGAVQWLKELGN
HHHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCC
PYLITLFDGDGMLGMDLGVYGAPETFLIDSNGIVRYRHVGDVNERNWNETLKPMYDQLVA
CEEEEEECCCCEEEECCCCCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
EAK
CCC
>Mature Secondary Structure
MNKNFLFAPLALFLILVAVFATQLTRNSNGDDPTKLESVLVGKPVPEFRLEDLAQEGKLY
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHH
DQSIFKGEPLLLNVWATWCPTCYAEHQYLNTLATEGVKIIGMNYKDDRAGAVQWLKELGN
HHHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHCCC
PYLITLFDGDGMLGMDLGVYGAPETFLIDSNGIVRYRHVGDVNERNWNETLKPMYDQLVA
CEEEEEECCCCEEEECCCCCCCCCEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
EAK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]