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The map label for this gene is ccmF [H]

Identifier: 59712426

GI number: 59712426

Start: 2054132

End: 2056090

Strand: Reverse

Name: ccmF [H]

Synonym: VF_1819

Alternate gene names: 59712426

Gene position: 2056090-2054132 (Counterclockwise)

Preceding gene: 59712427

Following gene: 59712425

Centisome position: 70.96

GC content: 41.6

Gene sequence:

>1959_bases
ATGATCGCAGAACTTGGTCACTTTGCAATGATTGCTTCATTAGGGCTTGCCGTCCTTTTGAGCATATTACCTATGTATGG
CGCAAGCCGTGGTAATAAAGCATTAATGCAGAGTGCAAGACCATTAGCTTGGGGGATGTTTTTACTTCTAAGTTTATCAT
TTGGAATTTTAATGTGGGCTTTCTACGTTAATGATTTCACTCTTCAGTATGTAGCAAGTAACTCAAACAGCTTATTACCT
TGGTACTATCGTTTAACCGCGGTTTGGGGTGCGCATGAAGGTTCACTATTACTTTGGGTATTAATCCAAGCTGGTTGGAC
TGTTGCTGTAGCGACATTCAGCCGTGGTATGCCACAAGAATCTGTTGCGCGTGTATTAGCAGTAATGGGGTGGATCACCG
TTGGTTTCTTACTGTTTATTATTTTAACCTCTAACCCATTCTTACGTACTCTGCCTTATTTCCCAATTGATGGTCGTGAC
TTAAACCCGCTGCTTCAAGATCCAGGTTTAATTATTCACCCTCCAATGCTTTACATGGGTTATGTTGGTTTCTCTGTTGC
ATTCTCTTTTGCAATTGCTTCATTAATGACAGGGCGTTTAGATACGGCTTGGGCTCGTTGGTCTCGTCCTTGGACTATCG
CTGCATGGTCATTCCTAACGGTAGGTATCTCTCTAGGTTCTTGGTGGGCGTACTATGAACTTGGCTGGGGTGGCTGGTGG
TTCTGGGATCCAGTAGAAAACGCATCATTTATGCCTTGGCTTGTTGGTACTGCATTAATGCACTCATTAGCAGTAACAGA
AAAGCGTGGTACGTTTAAAGCATGGACCGTATTACTGGCGATTTCAGCGTTCTCATTAAGCTTATTAGGCACATTCTTAG
TTCGTTCTGGTATTTTAGTATCAGTTCACGCCTTTGCATCAGATCCTTCTCGAGGCATGTTTATCCTCGGTTTCTTGGTG
ATGGTTATTGGTGGTTCACTATTACTGTTTGCCTTAAAAGGTGCATCAGTTCGTGTTCGAGGTAACTTCTCTCTGTTCTC
TCGTGAGAATGCGTTATTAGCAAATAACATTTTATTAGTTACAGCATTAGTTGTGGTACTTGTTGGTACTTTATTACCAC
TGGTTCATAAGCAACTAGGCTTAGGCTCTGTTTCAATTGGTGCTCCATTCTTCGACATGCTATTTGCATGGTTGATGATC
CCATTTGCTTTCCTACTGGGTATTGGTCCACTAATTCGTTGGAAGAAAGACAAACTAAGCAACCTATCAAAACGTCTTGT
GATTTCTGGTGCGATAACTGTACCGCTTGCTGCGTTAATGATGGTGATGTTTGCTGATAAATTCCAATTCATGCCGTATT
TAGGCTGGATGATGGCGATTTGGATTGTGATTTTACATGGATTTGAGTTGTATGAACGTGCTACGCACCGTCACTCATTC
TCTGTGGGTATTACTAAGCTAGGACGCAGTCACTGGGCTATGATTTTTGCTCATATTGGTCTTGCCGTTACGATTATCGG
TATTGCTATGGTGCAAAACTACAGTATTGAAAAAGATGTACGTTTAGCGCCAGGTGAACACATTGAAATGAATGGCTACC
AGTTCTATTTCGCAGGTGTTAGAGATACAGATGGTCCTAACTATGATGGTTATACCGCTGATTTTGATATTACATTAGAT
GGTAAAGCGATTAATACATTGCACGCTGAAAAACGTTTTTATGAAACTGCAGGTTCTATGATGACAGAAGCAGCGATTGA
TCGTGGTTTTACTCGTGACTTATACATCGCAATGGGTGAGCGTTTAGATGACAACCGTTCATGGGCTGTACGTATTTACT
ACAAACCATTCGTTCGTTGGATCTGGGCTGGTTCATTGTTTATGGCATTTGGTGGTGCATTAGCTATGTCTGATAAACGC
TATCGTTTCCGTAAAAATGCTAAAAAACAGGAAGCTTAA

Upstream 100 bases:

>100_bases
AACACGATGAAGAATACATGCCACCAGAAGTTGCAGAAGCGATGAAAAAGACACATGAACCGCTTCAGTATACTGAACAA
CAAAAACAAGGAACGGGTCA

Downstream 100 bases:

>100_bases
TTTATGAATAAGAACTTTTTATTTGCACCATTAGCGCTGTTTTTAATTTTAGTCGCTGTGTTTGCTACCCAGTTAACACG
CAACTCAAATGGTGATGATC

Product: heme lyase, CcmF subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MIAELGHFAMIASLGLAVLLSILPMYGASRGNKALMQSARPLAWGMFLLLSLSFGILMWAFYVNDFTLQYVASNSNSLLP
WYYRLTAVWGAHEGSLLLWVLIQAGWTVAVATFSRGMPQESVARVLAVMGWITVGFLLFIILTSNPFLRTLPYFPIDGRD
LNPLLQDPGLIIHPPMLYMGYVGFSVAFSFAIASLMTGRLDTAWARWSRPWTIAAWSFLTVGISLGSWWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEKRGTFKAWTVLLAISAFSLSLLGTFLVRSGILVSVHAFASDPSRGMFILGFLV
MVIGGSLLLFALKGASVRVRGNFSLFSRENALLANNILLVTALVVVLVGTLLPLVHKQLGLGSVSIGAPFFDMLFAWLMI
PFAFLLGIGPLIRWKKDKLSNLSKRLVISGAITVPLAALMMVMFADKFQFMPYLGWMMAIWIVILHGFELYERATHRHSF
SVGITKLGRSHWAMIFAHIGLAVTIIGIAMVQNYSIEKDVRLAPGEHIEMNGYQFYFAGVRDTDGPNYDGYTADFDITLD
GKAINTLHAEKRFYETAGSMMTEAAIDRGFTRDLYIAMGERLDDNRSWAVRIYYKPFVRWIWAGSLFMAFGGALAMSDKR
YRFRKNAKKQEA

Sequences:

>Translated_652_residues
MIAELGHFAMIASLGLAVLLSILPMYGASRGNKALMQSARPLAWGMFLLLSLSFGILMWAFYVNDFTLQYVASNSNSLLP
WYYRLTAVWGAHEGSLLLWVLIQAGWTVAVATFSRGMPQESVARVLAVMGWITVGFLLFIILTSNPFLRTLPYFPIDGRD
LNPLLQDPGLIIHPPMLYMGYVGFSVAFSFAIASLMTGRLDTAWARWSRPWTIAAWSFLTVGISLGSWWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEKRGTFKAWTVLLAISAFSLSLLGTFLVRSGILVSVHAFASDPSRGMFILGFLV
MVIGGSLLLFALKGASVRVRGNFSLFSRENALLANNILLVTALVVVLVGTLLPLVHKQLGLGSVSIGAPFFDMLFAWLMI
PFAFLLGIGPLIRWKKDKLSNLSKRLVISGAITVPLAALMMVMFADKFQFMPYLGWMMAIWIVILHGFELYERATHRHSF
SVGITKLGRSHWAMIFAHIGLAVTIIGIAMVQNYSIEKDVRLAPGEHIEMNGYQFYFAGVRDTDGPNYDGYTADFDITLD
GKAINTLHAEKRFYETAGSMMTEAAIDRGFTRDLYIAMGERLDDNRSWAVRIYYKPFVRWIWAGSLFMAFGGALAMSDKR
YRFRKNAKKQEA
>Mature_652_residues
MIAELGHFAMIASLGLAVLLSILPMYGASRGNKALMQSARPLAWGMFLLLSLSFGILMWAFYVNDFTLQYVASNSNSLLP
WYYRLTAVWGAHEGSLLLWVLIQAGWTVAVATFSRGMPQESVARVLAVMGWITVGFLLFIILTSNPFLRTLPYFPIDGRD
LNPLLQDPGLIIHPPMLYMGYVGFSVAFSFAIASLMTGRLDTAWARWSRPWTIAAWSFLTVGISLGSWWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEKRGTFKAWTVLLAISAFSLSLLGTFLVRSGILVSVHAFASDPSRGMFILGFLV
MVIGGSLLLFALKGASVRVRGNFSLFSRENALLANNILLVTALVVVLVGTLLPLVHKQLGLGSVSIGAPFFDMLFAWLMI
PFAFLLGIGPLIRWKKDKLSNLSKRLVISGAITVPLAALMMVMFADKFQFMPYLGWMMAIWIVILHGFELYERATHRHSF
SVGITKLGRSHWAMIFAHIGLAVTIIGIAMVQNYSIEKDVRLAPGEHIEMNGYQFYFAGVRDTDGPNYDGYTADFDITLD
GKAINTLHAEKRFYETAGSMMTEAAIDRGFTRDLYIAMGERLDDNRSWAVRIYYKPFVRWIWAGSLFMAFGGALAMSDKR
YRFRKNAKKQEA

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=649, Percent_Identity=62.8659476117103, Blast_Score=791, Evalue=0.0,
Organism=Escherichia coli, GI1790511, Length=352, Percent_Identity=50, Blast_Score=293, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 72904; Mature: 72904

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAELGHFAMIASLGLAVLLSILPMYGASRGNKALMQSARPLAWGMFLLLSLSFGILMWA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FYVNDFTLQYVASNSNSLLPWYYRLTAVWGAHEGSLLLWVLIQAGWTVAVATFSRGMPQE
HHHHCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHCCCCEEEEHHHCCCCHH
SVARVLAVMGWITVGFLLFIILTSNPFLRTLPYFPIDGRDLNPLLQDPGLIIHPPMLYMG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHCCCEEEECHHHHHH
YVGFSVAFSFAIASLMTGRLDTAWARWSRPWTIAAWSFLTVGISLGSWWAYYELGWGGWW
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEHHHHHHHHHHHCCEEEEEEECCCCEE
FWDPVENASFMPWLVGTALMHSLAVTEKRGTFKAWTVLLAISAFSLSLLGTFLVRSGILV
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SVHAFASDPSRGMFILGFLVMVIGGSLLLFALKGASVRVRGNFSLFSRENALLANNILLV
EEEEECCCCCCCHHHHHHHHHHHCCHHEEHEECCCEEEEEECEEEEECCCCHHHHHHHHH
TALVVVLVGTLLPLVHKQLGLGSVSIGAPFFDMLFAWLMIPFAFLLGIGPLIRWKKDKLS
HHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHCCCHHHEECHHHHH
NLSKRLVISGAITVPLAALMMVMFADKFQFMPYLGWMMAIWIVILHGFELYERATHRHSF
HHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVGITKLGRSHWAMIFAHIGLAVTIIGIAMVQNYSIEKDVRLAPGEHIEMNGYQFYFAGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCEEEEEEEC
RDTDGPNYDGYTADFDITLDGKAINTLHAEKRFYETAGSMMTEAAIDRGFTRDLYIAMGE
CCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
RLDDNRSWAVRIYYKPFVRWIWAGSLFMAFGGALAMSDKRYRFRKNAKKQEA
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHCCCCCCC
>Mature Secondary Structure
MIAELGHFAMIASLGLAVLLSILPMYGASRGNKALMQSARPLAWGMFLLLSLSFGILMWA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FYVNDFTLQYVASNSNSLLPWYYRLTAVWGAHEGSLLLWVLIQAGWTVAVATFSRGMPQE
HHHHCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHCCCCEEEEHHHCCCCHH
SVARVLAVMGWITVGFLLFIILTSNPFLRTLPYFPIDGRDLNPLLQDPGLIIHPPMLYMG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHCCCEEEECHHHHHH
YVGFSVAFSFAIASLMTGRLDTAWARWSRPWTIAAWSFLTVGISLGSWWAYYELGWGGWW
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEHHHHHHHHHHHCCEEEEEEECCCCEE
FWDPVENASFMPWLVGTALMHSLAVTEKRGTFKAWTVLLAISAFSLSLLGTFLVRSGILV
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SVHAFASDPSRGMFILGFLVMVIGGSLLLFALKGASVRVRGNFSLFSRENALLANNILLV
EEEEECCCCCCCHHHHHHHHHHHCCHHEEHEECCCEEEEEECEEEEECCCCHHHHHHHHH
TALVVVLVGTLLPLVHKQLGLGSVSIGAPFFDMLFAWLMIPFAFLLGIGPLIRWKKDKLS
HHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHCCCHHHEECHHHHH
NLSKRLVISGAITVPLAALMMVMFADKFQFMPYLGWMMAIWIVILHGFELYERATHRHSF
HHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVGITKLGRSHWAMIFAHIGLAVTIIGIAMVQNYSIEKDVRLAPGEHIEMNGYQFYFAGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECCEEEEEEEC
RDTDGPNYDGYTADFDITLDGKAINTLHAEKRFYETAGSMMTEAAIDRGFTRDLYIAMGE
CCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
RLDDNRSWAVRIYYKPFVRWIWAGSLFMAFGGALAMSDKRYRFRKNAKKQEA
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]