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The map label for this gene is prmB [C]

Identifier: 59712413

GI number: 59712413

Start: 2037571

End: 2038503

Strand: Reverse

Name: prmB [C]

Synonym: VF_1806

Alternate gene names: 59712413

Gene position: 2038503-2037571 (Counterclockwise)

Preceding gene: 59712415

Following gene: 59712412

Centisome position: 70.35

GC content: 42.02

Gene sequence:

>933_bases
TTGGATAAGATTTTTGTAGAAGAGGCGGTCGCTGAGCTTCATACGTTACAAGATATGCTGCGTTGGACGGTAAGTCGTTT
TAATGCTGCGGGTCTTTTTTATGGTCACGGTACAGATAACGCATGGGATGAAGCTGTTCAACTTGTGCTTCCAACACTGT
ACTTACCAATTGATGTGCCAGCGCATGTGCGTGAATCACGCTTAACATCAACAGAGCGTTTACGTATTGTTGAGCGTGTT
GTACGTCGTATTAATGAGCGTATTCCTACGGCTTATTTAACGAATAAAGCGTGGTTCTGTGGCCTTGAGTTTTTTGTTGA
TGAGCGTGTACTTGTGCCTCGTTCACCAATTGCAGAGTTGATTGAAACACAATTCGAACCGTGGTTAACCGAAGAGCCTA
CACGTATTATGGATTTATGTACGGGTAGTGGTTGTATTGCGATTGCGTGTGCTCATGCGTTCCCAAATGCGGAAGTAGAT
GCGATTGATATTTCGACGGATGCATTAATGGTTGCTGAACAAAATGTTCAAGATCATGGCATGGAGCAACAAGTGTTCCC
AATCCGCTCAGATCTATTACGTGATATTCCTAAAGATCAGTATAACTTCATTGTCTCTAACCCACCTTATGTGGATGAAG
AGGATATGAATAGCTTACCGGAAGAGTTTGAGCATGAACCTGAATTAGGTTTAGCAGCAGGTACAGATGGATTGAAGTTA
GTTCGTCGTATTTTAGCAAATGCACCAGATTATTTAATGGATAACGGTTTCTTAATCTGTGAAGTGGGTAACTCAATGGT
TCATATGATGGAGCAATACCCAGACATTCCATTTACTTGGATTGAGTTTGCGGAAGGTGGACATGGTGTATTCATGTTAA
CTAAGCAGCAACTTCTTGATTGCGCAGATGAGTTTGCTCTTTATCGCGACTAA

Upstream 100 bases:

>100_bases
ACGGAACAGCGAAAGTTCGTCATCTGATAGGTGGTCGTTTTTGCTCATTTTTAAATTCCAATAATTAACAGTAGTATTAT
AACTTGTTTTGGGGGCAATT

Downstream 100 bases:

>100_bases
ACCAAATTAATCTAAATGAAAGCCTGATGGAAACATCGGGCTTTTTTTATGCTTGTTTACTTTGTGACATTGCAAAATCC
AGTCGTTTGCGAAGTTCTTG

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDKIFVEEAVAELHTLQDMLRWTVSRFNAAGLFYGHGTDNAWDEAVQLVLPTLYLPIDVPAHVRESRLTSTERLRIVERV
VRRINERIPTAYLTNKAWFCGLEFFVDERVLVPRSPIAELIETQFEPWLTEEPTRIMDLCTGSGCIAIACAHAFPNAEVD
AIDISTDALMVAEQNVQDHGMEQQVFPIRSDLLRDIPKDQYNFIVSNPPYVDEEDMNSLPEEFEHEPELGLAAGTDGLKL
VRRILANAPDYLMDNGFLICEVGNSMVHMMEQYPDIPFTWIEFAEGGHGVFMLTKQQLLDCADEFALYRD

Sequences:

>Translated_310_residues
MDKIFVEEAVAELHTLQDMLRWTVSRFNAAGLFYGHGTDNAWDEAVQLVLPTLYLPIDVPAHVRESRLTSTERLRIVERV
VRRINERIPTAYLTNKAWFCGLEFFVDERVLVPRSPIAELIETQFEPWLTEEPTRIMDLCTGSGCIAIACAHAFPNAEVD
AIDISTDALMVAEQNVQDHGMEQQVFPIRSDLLRDIPKDQYNFIVSNPPYVDEEDMNSLPEEFEHEPELGLAAGTDGLKL
VRRILANAPDYLMDNGFLICEVGNSMVHMMEQYPDIPFTWIEFAEGGHGVFMLTKQQLLDCADEFALYRD
>Mature_310_residues
MDKIFVEEAVAELHTLQDMLRWTVSRFNAAGLFYGHGTDNAWDEAVQLVLPTLYLPIDVPAHVRESRLTSTERLRIVERV
VRRINERIPTAYLTNKAWFCGLEFFVDERVLVPRSPIAELIETQFEPWLTEEPTRIMDLCTGSGCIAIACAHAFPNAEVD
AIDISTDALMVAEQNVQDHGMEQQVFPIRSDLLRDIPKDQYNFIVSNPPYVDEEDMNSLPEEFEHEPELGLAAGTDGLKL
VRRILANAPDYLMDNGFLICEVGNSMVHMMEQYPDIPFTWIEFAEGGHGVFMLTKQQLLDCADEFALYRD

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=226, Percent_Identity=26.1061946902655, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI87082085, Length=310, Percent_Identity=71.6129032258065, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1787463, Length=199, Percent_Identity=34.1708542713568, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24582226, Length=213, Percent_Identity=24.4131455399061, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 35328; Mature: 35328

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIFVEEAVAELHTLQDMLRWTVSRFNAAGLFYGHGTDNAWDEAVQLVLPTLYLPIDVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCC
AHVRESRLTSTERLRIVERVVRRINERIPTAYLTNKAWFCGLEFFVDERVLVPRSPIAEL
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHEEHHHHHHCCEEECCCCHHHHH
IETQFEPWLTEEPTRIMDLCTGSGCIAIACAHAFPNAEVDAIDISTDALMVAEQNVQDHG
HHHHCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCEEEEECCCHHHCC
MEQQVFPIRSDLLRDIPKDQYNFIVSNPPYVDEEDMNSLPEEFEHEPELGLAAGTDGLKL
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHCCCHHHCCCCCCCEECCCHHHHH
VRRILANAPDYLMDNGFLICEVGNSMVHMMEQYPDIPFTWIEFAEGGHGVFMLTKQQLLD
HHHHHCCCCCHHHCCCEEEEECCCHHHHHHHHCCCCCEEHEEECCCCCEEEEEEHHHHHH
CADEFALYRD
HHHHHHHCCC
>Mature Secondary Structure
MDKIFVEEAVAELHTLQDMLRWTVSRFNAAGLFYGHGTDNAWDEAVQLVLPTLYLPIDVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCC
AHVRESRLTSTERLRIVERVVRRINERIPTAYLTNKAWFCGLEFFVDERVLVPRSPIAEL
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHEEHHHHHHCCEEECCCCHHHHH
IETQFEPWLTEEPTRIMDLCTGSGCIAIACAHAFPNAEVDAIDISTDALMVAEQNVQDHG
HHHHCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCEEEEECCCHHHCC
MEQQVFPIRSDLLRDIPKDQYNFIVSNPPYVDEEDMNSLPEEFEHEPELGLAAGTDGLKL
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHCCCHHHCCCCCCCEECCCHHHHH
VRRILANAPDYLMDNGFLICEVGNSMVHMMEQYPDIPFTWIEFAEGGHGVFMLTKQQLLD
HHHHHCCCCCHHHCCCEEEEECCCHHHHHHHHCCCCCEEHEEECCCCCEEEEEEHHHHHH
CADEFALYRD
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]