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The map label for this gene is aroC

Identifier: 59712412

GI number: 59712412

Start: 2035926

End: 2037011

Strand: Reverse

Name: aroC

Synonym: VF_1805

Alternate gene names: 59712412

Gene position: 2037011-2035926 (Counterclockwise)

Preceding gene: 59712413

Following gene: 59712409

Centisome position: 70.3

GC content: 42.91

Gene sequence:

>1086_bases
ATGGCTGGAAATTCTATAGGACAACATTTTCGAGTAACGACGTTTGGTGAAAGCCACGGGTTAGCGTTAGGCTGCATTGT
TGATGGCTGCCCTCCAGGTTTGGAATTAACCGAAGCTGATTTACAAGTTGATCTTGATCGTCGCAAACCGGGGACGTCAA
AATACACAACACAGCGCCGCGAAGCGGATGAAGTGAAGATCTTATCTGGTGTTTTTGAAGGAAAAACAACGGGTACTTCT
ATTGGTCTATTAATTGAAAATACAGATCAACGCTCAAAAGATTACTCTGAGATAAAAGATAAATTCCGCCCAGGCCATGC
AGATTACACTTACCATCAGAAGTATGGGCAACGTGATTACCGTGGTGGTGGTCGTTCATCCGCACGTGAAACTGCTATGC
GTGTTGCAGCAGGTGCAGTAGCTAAAAAGTATTTGAAGCAAGAGTTTGGTATTGAGATTCGAGCTTATTTATCACAAATG
GGCGATGTATCGATTGATTCTGTTGATTGGAATGAAATTGAAAATAATGCTTTTTTCTGCCCTGACGCGAGTAAAGTTGA
TGCTTTTGATGAGCTTATTCGTAAGTTAAAGAAAGAAGGTGACTCTATTGGAGCAAAGATCACGGTTGTAGCGCAAGGCG
TTCCTGTTGGTTTAGGCGAGCCGGTATTTGATCGTTTAGATGCAGATGTTGCTCATGCTCTTATGGGGATTAATGCTGTT
AAAGGTGTTGAGATTGGTGATGGCTTTGAAGTGGTTAATCAGCGTGGTTCTGAACATCGTGATCCATTGACGCCTGAAGG
TTTTAGCTCGAATCACGCCGGTGGTATTTTAGGTGGTATTTCATCTGGCCAAGATATTGTGGCTCATATTGCCTTAAAAC
CAACGTCAAGCATTACGGTTCCGGGTGAAACCATTACTCGTAGCGGAGAAAAAACAGAATTGATAACTAAAGGTCGTCAT
GATCCATGTGTTGGTATTCGTGCTGTGCCAATTGCAGAAGCGATGCTAGCGATTGTTGTAATGGATCACTTAGTACGTCA
TCGTGGACAAAACTTTGGTGTTCAAACTGAGACGCCTAAGATTTAG

Upstream 100 bases:

>100_bases
GGGTTTACTCTCAATACGATTCAAGCCAATATGGTTTTATTAAGAACTGATTGTTAGTCAGGTGAATGATGACTAATCAC
TTATATTTACAGAGGAAGTA

Downstream 100 bases:

>100_bases
TTGTAGGAGATAGGGACTAGTTTTTAGGGACGAATAAGAGCGAGTTAAAAGCGGGGGAGAATAGCCCCTACTACTGACAT
AAATAAAAAGAGCCAGATTG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAGNSIGQHFRVTTFGESHGLALGCIVDGCPPGLELTEADLQVDLDRRKPGTSKYTTQRREADEVKILSGVFEGKTTGTS
IGLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQEFGIEIRAYLSQM
GDVSIDSVDWNEIENNAFFCPDASKVDAFDELIRKLKKEGDSIGAKITVVAQGVPVGLGEPVFDRLDADVAHALMGINAV
KGVEIGDGFEVVNQRGSEHRDPLTPEGFSSNHAGGILGGISSGQDIVAHIALKPTSSITVPGETITRSGEKTELITKGRH
DPCVGIRAVPIAEAMLAIVVMDHLVRHRGQNFGVQTETPKI

Sequences:

>Translated_361_residues
MAGNSIGQHFRVTTFGESHGLALGCIVDGCPPGLELTEADLQVDLDRRKPGTSKYTTQRREADEVKILSGVFEGKTTGTS
IGLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQEFGIEIRAYLSQM
GDVSIDSVDWNEIENNAFFCPDASKVDAFDELIRKLKKEGDSIGAKITVVAQGVPVGLGEPVFDRLDADVAHALMGINAV
KGVEIGDGFEVVNQRGSEHRDPLTPEGFSSNHAGGILGGISSGQDIVAHIALKPTSSITVPGETITRSGEKTELITKGRH
DPCVGIRAVPIAEAMLAIVVMDHLVRHRGQNFGVQTETPKI
>Mature_360_residues
AGNSIGQHFRVTTFGESHGLALGCIVDGCPPGLELTEADLQVDLDRRKPGTSKYTTQRREADEVKILSGVFEGKTTGTSI
GLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGQRDYRGGGRSSARETAMRVAAGAVAKKYLKQEFGIEIRAYLSQMG
DVSIDSVDWNEIENNAFFCPDASKVDAFDELIRKLKKEGDSIGAKITVVAQGVPVGLGEPVFDRLDADVAHALMGINAVK
GVEIGDGFEVVNQRGSEHRDPLTPEGFSSNHAGGILGGISSGQDIVAHIALKPTSSITVPGETITRSGEKTELITKGRHD
PCVGIRAVPIAEAMLAIVVMDHLVRHRGQNFGVQTETPKI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=79.7222222222222, Blast_Score=578, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6321290, Length=370, Percent_Identity=46.2162162162162, Blast_Score=315, Evalue=6e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_VIBF1 (Q5E3U6)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_205188.1
- ProteinModelPortal:   Q5E3U6
- SMR:   Q5E3U6
- STRING:   Q5E3U6
- GeneID:   3278946
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_1805
- NMPDR:   fig|312309.3.peg.1804
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q5E3U6
- ProtClustDB:   PRK05382
- BioCyc:   VFIS312309:VF1805-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39003; Mature: 38872

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQHFRVTTFGESHGLALGCIVDGCPPGLELTEADLQVDLDRRKPGTSKYTTQRR
CCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEECCCEEEEECCCCCCCCCHHHHHH
EADEVKILSGVFEGKTTGTSIGLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGQRDY
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAMRVAAGAVAKKYLKQEFGIEIRAYLSQMGDVSIDSVDWNEIENNAFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCHHHCCCCEEEC
PDASKVDAFDELIRKLKKEGDSIGAKITVVAQGVPVGLGEPVFDRLDADVAHALMGINAV
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFEVVNQRGSEHRDPLTPEGFSSNHAGGILGGISSGQDIVAHIALKPTSSITV
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEC
PGETITRSGEKTELITKGRHDPCVGIRAVPIAEAMLAIVVMDHLVRHRGQNFGVQTETPK
CCHHHHCCCCCHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
I
C
>Mature Secondary Structure 
AGNSIGQHFRVTTFGESHGLALGCIVDGCPPGLELTEADLQVDLDRRKPGTSKYTTQRR
CCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEECCCEEEEECCCCCCCCCHHHHHH
EADEVKILSGVFEGKTTGTSIGLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGQRDY
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCC
RGGGRSSARETAMRVAAGAVAKKYLKQEFGIEIRAYLSQMGDVSIDSVDWNEIENNAFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCHHHCCCCEEEC
PDASKVDAFDELIRKLKKEGDSIGAKITVVAQGVPVGLGEPVFDRLDADVAHALMGINAV
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFEVVNQRGSEHRDPLTPEGFSSNHAGGILGGISSGQDIVAHIALKPTSSITV
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEC
PGETITRSGEKTELITKGRHDPCVGIRAVPIAEAMLAIVVMDHLVRHRGQNFGVQTETPK
CCHHHHCCCCCHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA