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The map label for this gene is fpr [H]

Identifier: 59712387

GI number: 59712387

Start: 2008659

End: 2009432

Strand: Reverse

Name: fpr [H]

Synonym: VF_1780

Alternate gene names: 59712387

Gene position: 2009432-2008659 (Counterclockwise)

Preceding gene: 59712388

Following gene: 59712386

Centisome position: 69.35

GC content: 36.95

Gene sequence:

>774_bases
ATGACAGAAATTCCTCATGGCTTAATTAAAGGCGTTGTCTTAAAACGCCATGATTGGACGGATAGATTATTTAGTCTGTT
TGTTGAAGCGCCAATCAATGCTTATCAAGCGGGACAGTTTACCAAGTTGGCATTATTAAATGATAAAGGTGACTGGGTAA
GAAGAGCTTATTCTATCGTAAATACCCCTGAGCATATTGAAGGGCGAGAGCGAATGGAATTTCTGATCATAGCCGATCAA
AAGGGAGAGTTATCTCCTTGTTTGCAAAAACTGAATTCTGGTGACGAGATTTTTGTAGGTAAAGACGCCAGTGGTTTTAT
GACTATTGATGAAGTTCCTAAAAATGCAGATGATTTTTGGTTGCTTTCAACAGGTACTGCCATTGGCCCATTTATATCGA
TATTAGAAACACCAGAACTTGAAATACGCTTTAAAAATTTTGTGTTAGTTCATGCGGTAAGAACAGAGTCTGAACTGATT
TATCAACAACGAATTGAACAGTTATCTAAACGATATAACAAGAGGTTTCATTATGTACCAATTGTTTCTAGAGAATATGT
CAGCGGAGCTTTATGTGGACGAATCCCGTCTTTATTACTCAACGGAGAGCTTGAAAAGAGAGCAGAACTTCAACTTAGTA
AAACATCTAGCTTCTTATATATTTGTGGTAACCCAAACATGGTTAAAGACACATCTGACGCACTAAAAGAATTAGGTTTT
GAAAAGCATTTACGTCGGAAACTTGGGCAATTTAGCTCAGAAAATTATTGGTAG

Upstream 100 bases:

>100_bases
AATAATCAATTAACGGGATTTGTAGTGACAAATGAGCGAGTTAAAAATGCTTTCCCACTATTTAGAGAGTTAAATACAAC
GAATTAAAAAGAGGTGAACT

Downstream 100 bases:

>100_bases
TGATTCGCTCTGTTTGAATCATACAAAACAATTTGGAGAAATATTATGAGTCATTTACGTATCCCAAAAAATTGGACAAT
TCAACGTTCAACGCCATTCT

Product: ferredoxin-NADP reductase

Products: NA

Alternate protein names: FNR; DA1; Flavodoxin reductase; FLDR; FLXR; Methyl viologen resistance protein A [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTEIPHGLIKGVVLKRHDWTDRLFSLFVEAPINAYQAGQFTKLALLNDKGDWVRRAYSIVNTPEHIEGRERMEFLIIADQ
KGELSPCLQKLNSGDEIFVGKDASGFMTIDEVPKNADDFWLLSTGTAIGPFISILETPELEIRFKNFVLVHAVRTESELI
YQQRIEQLSKRYNKRFHYVPIVSREYVSGALCGRIPSLLLNGELEKRAELQLSKTSSFLYICGNPNMVKDTSDALKELGF
EKHLRRKLGQFSSENYW

Sequences:

>Translated_257_residues
MTEIPHGLIKGVVLKRHDWTDRLFSLFVEAPINAYQAGQFTKLALLNDKGDWVRRAYSIVNTPEHIEGRERMEFLIIADQ
KGELSPCLQKLNSGDEIFVGKDASGFMTIDEVPKNADDFWLLSTGTAIGPFISILETPELEIRFKNFVLVHAVRTESELI
YQQRIEQLSKRYNKRFHYVPIVSREYVSGALCGRIPSLLLNGELEKRAELQLSKTSSFLYICGNPNMVKDTSDALKELGF
EKHLRRKLGQFSSENYW
>Mature_256_residues
TEIPHGLIKGVVLKRHDWTDRLFSLFVEAPINAYQAGQFTKLALLNDKGDWVRRAYSIVNTPEHIEGRERMEFLIIADQK
GELSPCLQKLNSGDEIFVGKDASGFMTIDEVPKNADDFWLLSTGTAIGPFISILETPELEIRFKNFVLVHAVRTESELIY
QQRIEQLSKRYNKRFHYVPIVSREYVSGALCGRIPSLLLNGELEKRAELQLSKTSSFLYICGNPNMVKDTSDALKELGFE
KHLRRKLGQFSSENYW

Specific function: Transports electrons between flavodoxin or ferredoxin and NADPH. Involved in the reductive activation of cobalamin- independent methionine synthase, pyruvate formate lyase and anaerobic ribonucleotide reductase. Also protects against superoxide radicals d

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=250, Percent_Identity=46.4, Blast_Score=222, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 29458; Mature: 29327

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIPHGLIKGVVLKRHDWTDRLFSLFVEAPINAYQAGQFTKLALLNDKGDWVRRAYSIV
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHC
NTPEHIEGRERMEFLIIADQKGELSPCLQKLNSGDEIFVGKDASGFMTIDEVPKNADDFW
CCCHHCCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEECCCCCCEEHHCCCCCCCCEE
LLSTGTAIGPFISILETPELEIRFKNFVLVHAVRTESELIYQQRIEQLSKRYNKRFHYVP
EEECCCHHHHHHHHHCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEE
IVSREYVSGALCGRIPSLLLNGELEKRAELQLSKTSSFLYICGNPNMVKDTSDALKELGF
ECCHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCEEEEECCCCCCCCHHHHHHHCCH
EKHLRRKLGQFSSENYW
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TEIPHGLIKGVVLKRHDWTDRLFSLFVEAPINAYQAGQFTKLALLNDKGDWVRRAYSIV
CCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHC
NTPEHIEGRERMEFLIIADQKGELSPCLQKLNSGDEIFVGKDASGFMTIDEVPKNADDFW
CCCHHCCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEECCCCCCEEHHCCCCCCCCEE
LLSTGTAIGPFISILETPELEIRFKNFVLVHAVRTESELIYQQRIEQLSKRYNKRFHYVP
EEECCCHHHHHHHHHCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEE
IVSREYVSGALCGRIPSLLLNGELEKRAELQLSKTSSFLYICGNPNMVKDTSDALKELGF
ECCHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCEEEEECCCCCCCCHHHHHHHCCH
EKHLRRKLGQFSSENYW
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8449868; 8346018; 9278503; 1400248; 2834327; 7961651; 9149148 [H]