Click here to switch to the map view.

The map label for this gene is norW [H]

Identifier: 59712388

GI number: 59712388

Start: 2009446

End: 2010594

Strand: Reverse

Name: norW [H]

Synonym: VF_1781

Alternate gene names: 59712388

Gene position: 2010594-2009446 (Counterclockwise)

Preceding gene: 59712389

Following gene: 59712387

Centisome position: 69.39

GC content: 36.99

Gene sequence:

>1149_bases
ATGATGAGTTTACCTATCGTTATTATTGGTAGTGGTTTTGCCTCTTACCAATTAATTAAAACCATTCGTCGAACTAACAA
TGATTGTCCAATTCATGTCTTTACGAATGACAGTGGTGACGATTATAACAAGCCAGATTTGAGTCACGTATTTTCAAAAC
AACAAAGCCCAGAAGAGGTAGTTACATTATCTGGAGGGGATTTTGCTGAGCAATACAATGTCATTCTACATAGGCACACT
TGGGTTGAGTCGATAGATACTGAGATCCAAGCCATTACTGCAAATGGTGAGCAATATGCTTATGGAAAATTGGTCTTAGC
GACAGGCTCTCAAACATTTATTCCACCTTTTCATGGTGATGGATGTGGAGATATCCTGACGTTAAATAGCCTAAAAGAAT
TTGCTGGTATTCAACAAAAAGTACTGGAGTCTAAAAAAGTACTTGTTGTTGGTGGTGGTTTAATAGGTACAGAGCTCGCA
ATGGATTTGGCAAATGCAGGAAAAATGGTGACCTTGGTTGAACCAAATACCCATTTATTAGCCAATATGGTGCCTGATTT
TATCTCTTTACCGCTTGAGAAAGCTTGTAAAGAAAAGGGAATTACTGTCAATTTATCCGATTGTGTGCAAGCCGTGAATA
AGCAAGAACAAGGTTACAGAGTAACAACCAGTAATGGTCATTCATATTATGTTGATTGCGTAATATCGGCAGCAGGATTA
AAACCTAATACGAAATTAGCAACAGAAGCAAATCTCATGGTTAATCGGGGAATTGTGGTGGATTTAAATTTACAAACATC
AGCTAATAATATCTATGCTTTAGGTGACTGTGCGGAAATTGAAGGCAAAGTTATGGCGTATCTTCAACCTATTTTATTAA
GCGCGAATGCATTAGCCAAAACACTATTAGGTACAGATACTGCTCTTTCTATGCCTAATATGATGGTGAAAGTGAAAACA
CCTAATTATCCAATACAGTTAGCTGGCAATACATCCACTGATATCGAGCGATGGTCTGTTGATATTGATACACAAGGCTT
GTGTGCTAAAGCTTACAACATAAATAATCAATTAACGGGATTTGTAGTGACAAATGAGCGAGTTAAAAATGCTTTCCCAC
TATTTAGAGAGTTAAATACAACGAATTAA

Upstream 100 bases:

>100_bases
AACCAAATACACCGTGGTCTTCAGTTCCTAATGATTTCTTATGCCCTGAATGTCATTTAGGTAAAGACGTATTTGTGGAA
ATTAAGTAGTTGGAGGATAA

Downstream 100 bases:

>100_bases
AAAGAGGTGAACTATGACAGAAATTCCTCATGGCTTAATTAAAGGCGTTGTCTTAAAACGCCATGATTGGACGGATAGAT
TATTTAGTCTGTTTGTTGAA

Product: nitric oxide reductase

Products: NAD; reduced flavorubredoxin; H2O [C]

Alternate protein names: Flavorubredoxin reductase; FlRd-reductase; FlavoRb reductase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MMSLPIVIIGSGFASYQLIKTIRRTNNDCPIHVFTNDSGDDYNKPDLSHVFSKQQSPEEVVTLSGGDFAEQYNVILHRHT
WVESIDTEIQAITANGEQYAYGKLVLATGSQTFIPPFHGDGCGDILTLNSLKEFAGIQQKVLESKKVLVVGGGLIGTELA
MDLANAGKMVTLVEPNTHLLANMVPDFISLPLEKACKEKGITVNLSDCVQAVNKQEQGYRVTTSNGHSYYVDCVISAAGL
KPNTKLATEANLMVNRGIVVDLNLQTSANNIYALGDCAEIEGKVMAYLQPILLSANALAKTLLGTDTALSMPNMMVKVKT
PNYPIQLAGNTSTDIERWSVDIDTQGLCAKAYNINNQLTGFVVTNERVKNAFPLFRELNTTN

Sequences:

>Translated_382_residues
MMSLPIVIIGSGFASYQLIKTIRRTNNDCPIHVFTNDSGDDYNKPDLSHVFSKQQSPEEVVTLSGGDFAEQYNVILHRHT
WVESIDTEIQAITANGEQYAYGKLVLATGSQTFIPPFHGDGCGDILTLNSLKEFAGIQQKVLESKKVLVVGGGLIGTELA
MDLANAGKMVTLVEPNTHLLANMVPDFISLPLEKACKEKGITVNLSDCVQAVNKQEQGYRVTTSNGHSYYVDCVISAAGL
KPNTKLATEANLMVNRGIVVDLNLQTSANNIYALGDCAEIEGKVMAYLQPILLSANALAKTLLGTDTALSMPNMMVKVKT
PNYPIQLAGNTSTDIERWSVDIDTQGLCAKAYNINNQLTGFVVTNERVKNAFPLFRELNTTN
>Mature_382_residues
MMSLPIVIIGSGFASYQLIKTIRRTNNDCPIHVFTNDSGDDYNKPDLSHVFSKQQSPEEVVTLSGGDFAEQYNVILHRHT
WVESIDTEIQAITANGEQYAYGKLVLATGSQTFIPPFHGDGCGDILTLNSLKEFAGIQQKVLESKKVLVVGGGLIGTELA
MDLANAGKMVTLVEPNTHLLANMVPDFISLPLEKACKEKGITVNLSDCVQAVNKQEQGYRVTTSNGHSYYVDCVISAAGL
KPNTKLATEANLMVNRGIVVDLNLQTSANNIYALGDCAEIEGKVMAYLQPILLSANALAKTLLGTDTALSMPNMMVKVKT
PNYPIQLAGNTSTDIERWSVDIDTQGLCAKAYNINNQLTGFVVTNERVKNAFPLFRELNTTN

Specific function: One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1789065, Length=377, Percent_Identity=45.6233421750663, Blast_Score=347, Evalue=8e-97,
Organism=Escherichia coli, GI1788892, Length=280, Percent_Identity=26.0714285714286, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789765, Length=326, Percent_Identity=26.9938650306748, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559934, Length=278, Percent_Identity=29.8561151079137, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24581020, Length=314, Percent_Identity=22.2929936305732, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573993, Length=314, Percent_Identity=22.2929936305732, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 41524; Mature: 41524

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSLPIVIIGSGFASYQLIKTIRRTNNDCPIHVFTNDSGDDYNKPDLSHVFSKQQSPEEV
CCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCE
VTLSGGDFAEQYNVILHRHTWVESIDTEIQAITANGEQYAYGKLVLATGSQTFIPPFHGD
EEECCCCHHHHHEEEEEECHHHHHCCCEEEEEEECCCEEEEEEEEEEECCCEECCCCCCC
GCGDILTLNSLKEFAGIQQKVLESKKVLVVGGGLIGTELAMDLANAGKMVTLVEPNTHLL
CCCCEEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCCHHH
ANMVPDFISLPLEKACKEKGITVNLSDCVQAVNKQEQGYRVTTSNGHSYYVDCVISAAGL
HHHCHHHHHCCHHHHHHHCCCEEEHHHHHHHHCCCCCCEEEEECCCCEEEEEEEEEECCC
KPNTKLATEANLMVNRGIVVDLNLQTSANNIYALGDCAEIEGKVMAYLQPILLSANALAK
CCCCCEEEECCEEEECCEEEEEEEEECCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHH
TLLGTDTALSMPNMMVKVKTPNYPIQLAGNTSTDIERWSVDIDTQGLCAKAYNINNQLTG
HHHCCCHHCCCCCEEEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEEEEECCCCCEEE
FVVTNERVKNAFPLFRELNTTN
EEEECHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMSLPIVIIGSGFASYQLIKTIRRTNNDCPIHVFTNDSGDDYNKPDLSHVFSKQQSPEEV
CCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCE
VTLSGGDFAEQYNVILHRHTWVESIDTEIQAITANGEQYAYGKLVLATGSQTFIPPFHGD
EEECCCCHHHHHEEEEEECHHHHHCCCEEEEEEECCCEEEEEEEEEEECCCEECCCCCCC
GCGDILTLNSLKEFAGIQQKVLESKKVLVVGGGLIGTELAMDLANAGKMVTLVEPNTHLL
CCCCEEEHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCCEEEEECCCCHHH
ANMVPDFISLPLEKACKEKGITVNLSDCVQAVNKQEQGYRVTTSNGHSYYVDCVISAAGL
HHHCHHHHHCCHHHHHHHCCCEEEHHHHHHHHCCCCCCEEEEECCCCEEEEEEEEEECCC
KPNTKLATEANLMVNRGIVVDLNLQTSANNIYALGDCAEIEGKVMAYLQPILLSANALAK
CCCCCEEEECCEEEECCEEEEEEEEECCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHH
TLLGTDTALSMPNMMVKVKTPNYPIQLAGNTSTDIERWSVDIDTQGLCAKAYNINNQLTG
HHHCCCHHCCCCCEEEEEECCCCCEEECCCCCCCCEEEEEEECCCCCEEEEECCCCCEEE
FVVTNERVKNAFPLFRELNTTN
EEEECHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; oxidized flavorubredoxin; O2 [C]

Specific reaction: NADH + oxidized flavorubredoxin + O2 = NAD + reduced flavorubredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA