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The map label for this gene is usg [H]

Identifier: 59712305

GI number: 59712305

Start: 1913861

End: 1914874

Strand: Reverse

Name: usg [H]

Synonym: VF_1698

Alternate gene names: 59712305

Gene position: 1914874-1913861 (Counterclockwise)

Preceding gene: 59712306

Following gene: 59712304

Centisome position: 66.09

GC content: 41.12

Gene sequence:

>1014_bases
ATGACTCAAGAATTTGATGTTGCCATTCTTGGCGCAACTGGTGCCGTTGGCGAAGCAATCGTAGAAGTATTACAAGATCG
TAATTTTCCGGTTCGCAATTTATACCTTTTAGCGTCAGAGCGCAGTGAAGGTAAAACAGTTCGTTTTAATGGTAAAACAT
TAACCGTTGAGAACGTAGAAGAGTTTGATTGGAGCCAAGTACAAATTGGTTTATTTTCAGCAGGTGGTGAATTATCCGCT
AAATGGGCACCAATCGCAGCGGATTCAGGTGTCGTTGTTATCGATAACACATCACACTTCCGTTACGATCACGATATTCC
ATTGGTGATTCCTGAAGTGAACCCAGAAGCGTTAGCTGATTTCCGTAATCGTAATATTATTGCGAACCCTAACTGTTCAA
CGATTCAAATGTTAGTTGCTTTAAAACCGATTCACGATGCTGTAGGTATTGATCGTATCAACGTATCAACATACCAATCA
GTATCTGGTTCAGGTAAAGCGGGTATTGATGAGCTAGCGGGTCAAACAGCTAAATTGCTAAATGGCTTACCAGCAGAGAA
CAAAGCTTACGATAAGCAAATTGCGTTTAACTGTTTACCTCACATTGATGAGTTTATGGATAACGGCTACACCAAAGAAG
AAATGAAAATGGTGTGGGAAACGCAAAAAATCTTTGCTGATGATACGATTACAGTAAACCCAACATGTGTACGTGTACCA
GTATTCTACGGTCACGCAGAAGCCGTTCATATTGAAACTCGTGCTCCAATCGATGCTGCAGAAGCAACACGTTTACTTGA
AGAAACCGATGGTATCGAAGTTTTCCACGGTAATGATTATCCAACACAAGTAAGCGACGCTACGGGTAAAGAGCACGTAA
TGGTGGCTCGTATTCGTGAAGATATTAGCCATTCAATGGGCTTAAATATGTGGGTAGTTGCAGATAATGTACGTAAAGGC
GCTGCAACAAACGCAGTTCAAATTGCTGAAGTGTTAATCCGTGATTACTACTAA

Upstream 100 bases:

>100_bases
ATTGGGATAGAAGAGAATACAGTGCTATCACGATCACAGGGACTCAATGCTGTGATCTTACTCCGTTACAACAACTTGGA
TTTACAATCGAGGAAGTCTA

Downstream 100 bases:

>100_bases
TAATAATGCGTTAACTTGTTTTTTATAAAATAAAGAGCGTTATTTACTTTAAATTAAAAGCCTTAGTGAAAACTAAGGCT
TTTTTCTTCCATAAAGCACA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTQEFDVAILGATGAVGEAIVEVLQDRNFPVRNLYLLASERSEGKTVRFNGKTLTVENVEEFDWSQVQIGLFSAGGELSA
KWAPIAADSGVVVIDNTSHFRYDHDIPLVIPEVNPEALADFRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQS
VSGSGKAGIDELAGQTAKLLNGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADDTITVNPTCVRVP
VFYGHAEAVHIETRAPIDAAEATRLLEETDGIEVFHGNDYPTQVSDATGKEHVMVARIREDISHSMGLNMWVVADNVRKG
AATNAVQIAEVLIRDYY

Sequences:

>Translated_337_residues
MTQEFDVAILGATGAVGEAIVEVLQDRNFPVRNLYLLASERSEGKTVRFNGKTLTVENVEEFDWSQVQIGLFSAGGELSA
KWAPIAADSGVVVIDNTSHFRYDHDIPLVIPEVNPEALADFRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQS
VSGSGKAGIDELAGQTAKLLNGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADDTITVNPTCVRVP
VFYGHAEAVHIETRAPIDAAEATRLLEETDGIEVFHGNDYPTQVSDATGKEHVMVARIREDISHSMGLNMWVVADNVRKG
AATNAVQIAEVLIRDYY
>Mature_336_residues
TQEFDVAILGATGAVGEAIVEVLQDRNFPVRNLYLLASERSEGKTVRFNGKTLTVENVEEFDWSQVQIGLFSAGGELSAK
WAPIAADSGVVVIDNTSHFRYDHDIPLVIPEVNPEALADFRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQSV
SGSGKAGIDELAGQTAKLLNGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADDTITVNPTCVRVPV
FYGHAEAVHIETRAPIDAAEATRLLEETDGIEVFHGNDYPTQVSDATGKEHVMVARIREDISHSMGLNMWVVADNVRKGA
ATNAVQIAEVLIRDYY

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=45.4005934718101, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=24.6498599439776, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320362, Length=387, Percent_Identity=28.4237726098191, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37106; Mature: 36975

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQEFDVAILGATGAVGEAIVEVLQDRNFPVRNLYLLASERSEGKTVRFNGKTLTVENVE
CCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEECCCEEEECCCC
EFDWSQVQIGLFSAGGELSAKWAPIAADSGVVVIDNTSHFRYDHDIPLVIPEVNPEALAD
CCCCCEEEEEEEECCCCCCCEECEEECCCCEEEEECCCCEEECCCCCEEEECCCHHHHHH
FRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQSVSGSGKAGIDELAGQTAKLL
HHCCCEEECCCCHHEEEEEHHHHHHHHCCCCEEECHHHHCCCCCCCCCHHHHHHHHHHHH
NGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADDTITVNPTCVRVP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCEEEEEE
VFYGHAEAVHIETRAPIDAAEATRLLEETDGIEVFHGNDYPTQVSDATGKEHVMVARIRE
EEECCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEHHHHHH
DISHSMGLNMWVVADNVRKGAATNAVQIAEVLIRDYY
HHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TQEFDVAILGATGAVGEAIVEVLQDRNFPVRNLYLLASERSEGKTVRFNGKTLTVENVE
CCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEECCCEEEECCCC
EFDWSQVQIGLFSAGGELSAKWAPIAADSGVVVIDNTSHFRYDHDIPLVIPEVNPEALAD
CCCCCEEEEEEEECCCCCCCEECEEECCCCEEEEECCCCEEECCCCCEEEECCCHHHHHH
FRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQSVSGSGKAGIDELAGQTAKLL
HHCCCEEECCCCHHEEEEEHHHHHHHHCCCCEEECHHHHCCCCCCCCCHHHHHHHHHHHH
NGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADDTITVNPTCVRVP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCEEEEEE
VFYGHAEAVHIETRAPIDAAEATRLLEETDGIEVFHGNDYPTQVSDATGKEHVMVARIRE
EEECCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEHHHHHH
DISHSMGLNMWVVADNVRKGAATNAVQIAEVLIRDYY
HHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]