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The map label for this gene is sprE [H]

Identifier: 59712296

GI number: 59712296

Start: 1901307

End: 1902413

Strand: Reverse

Name: sprE [H]

Synonym: VF_1689

Alternate gene names: 59712296

Gene position: 1902413-1901307 (Counterclockwise)

Preceding gene: 59712298

Following gene: 59712295

Centisome position: 65.66

GC content: 36.95

Gene sequence:

>1107_bases
ATGTCAGTAGAGCAGGCAACAAAAAAAAAGGAAGGAGAGGGTAACGCTCCTGTAGAAGATTTATTGTTAAACAAAGATAT
TTTGATTGTTGATGATGATCCAATCTTTCGTTCAATGATTAGAGCGGTCTTAGAAGCTTATTCATGCAATGTTAAAGAAG
CGAACAACGGCCTTGAAGGTTTACAAATGCTTAAGCATTCTTTACCTGATGTATTGTTGTGTGATTTAGCTATGCCAATA
TTAAATGGCATTGAATTTGTAGAGGAAGCGGTATTGGAATATCCAATGCTTCCAATCATTGTTATTTCAGGTAGTGGTGA
TATGCAAGATGTCGCTAAGGTGTTGCGTTTAGGAGCAAAAGATTTTCTTGTTAAACCAATCAGTGATGTCTCGATTTTAA
TTAAATCGCTTTCTTCTGCATTAAAGCTAAGTGAAGAAAGCTCGTTAAGAATGCAAGATTTTTCTAGTCAGTGGTTTAGA
ACATCAGAGCTTGATAAAAGCTGTAATGATGAACTGCATTGGCATTTAGAATACTTACAAGAAGAGCCGAACGTAGGACG
AGAATTACTGTTTGAGTTGTTACCTGAAAGTGAGGCTCAACATGCCAATTGGAAGTTAAGTTATCGTTTATTGCAGTCAA
CGGATGGTATGCCTTTAATCTTTGATTATGAATGGCTATTGGATGGACGTTTATTTTTCTACCTTGTTGATTCACATTCC
GGTGGGGAAAATGGCGTTATCTCTTGTTTATTGATCAGAGCGTTTTTTAATGATTTTATTCGAGAGCAGCAGATGTCAAC
AAATACTATATCGGCAATGGTGGCATCCATAGAAAAAGGCATGGGAACAATGGAAAATAGCCAAGCAATGTCTGGTGTTT
TTGGCTATGTGGATTTGTCTGAGCAAGCGGTATTTATTTTGTCTGCGGGTCTGGATGCTATCTGGGAAAGTAATAATCAA
CGTAATGTTTTAAGAGCAAATAACCAATTAACCACTCATGCCTCAACCAATCAGGTTCATCGTTTTTCAGTGAAAGAAGG
TATGAACAGTCTTTCATTAAATAACGTGGGATGCAGCAGTTTTAAGTTAGAATTGACATCGTTTTAG

Upstream 100 bases:

>100_bases
TAGCTAAAATTATTTGTGCTCACTTAGATCTCGAACTAAATTTATTTTAGATAATAAAAATAATAGGTACTGAATTTGGG
TGCGTGCAGAGGGTAGTAGT

Downstream 100 bases:

>100_bases
AATTGATTAAAGTCATTGTTGTTTACACTTCAATTAACTTTTTGATTCTTTAGAGGCTAATTTGCATTTTACCCGTAAAG
TATTTTGGTTTGTTGCTGGA

Product: proteolytic adapter for RpoS degradation by ClpXP (RssB, ExpM)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSVEQATKKKEGEGNAPVEDLLLNKDILIVDDDPIFRSMIRAVLEAYSCNVKEANNGLEGLQMLKHSLPDVLLCDLAMPI
LNGIEFVEEAVLEYPMLPIIVISGSGDMQDVAKVLRLGAKDFLVKPISDVSILIKSLSSALKLSEESSLRMQDFSSQWFR
TSELDKSCNDELHWHLEYLQEEPNVGRELLFELLPESEAQHANWKLSYRLLQSTDGMPLIFDYEWLLDGRLFFYLVDSHS
GGENGVISCLLIRAFFNDFIREQQMSTNTISAMVASIEKGMGTMENSQAMSGVFGYVDLSEQAVFILSAGLDAIWESNNQ
RNVLRANNQLTTHASTNQVHRFSVKEGMNSLSLNNVGCSSFKLELTSF

Sequences:

>Translated_368_residues
MSVEQATKKKEGEGNAPVEDLLLNKDILIVDDDPIFRSMIRAVLEAYSCNVKEANNGLEGLQMLKHSLPDVLLCDLAMPI
LNGIEFVEEAVLEYPMLPIIVISGSGDMQDVAKVLRLGAKDFLVKPISDVSILIKSLSSALKLSEESSLRMQDFSSQWFR
TSELDKSCNDELHWHLEYLQEEPNVGRELLFELLPESEAQHANWKLSYRLLQSTDGMPLIFDYEWLLDGRLFFYLVDSHS
GGENGVISCLLIRAFFNDFIREQQMSTNTISAMVASIEKGMGTMENSQAMSGVFGYVDLSEQAVFILSAGLDAIWESNNQ
RNVLRANNQLTTHASTNQVHRFSVKEGMNSLSLNNVGCSSFKLELTSF
>Mature_367_residues
SVEQATKKKEGEGNAPVEDLLLNKDILIVDDDPIFRSMIRAVLEAYSCNVKEANNGLEGLQMLKHSLPDVLLCDLAMPIL
NGIEFVEEAVLEYPMLPIIVISGSGDMQDVAKVLRLGAKDFLVKPISDVSILIKSLSSALKLSEESSLRMQDFSSQWFRT
SELDKSCNDELHWHLEYLQEEPNVGRELLFELLPESEAQHANWKLSYRLLQSTDGMPLIFDYEWLLDGRLFFYLVDSHSG
GENGVISCLLIRAFFNDFIREQQMSTNTISAMVASIEKGMGTMENSQAMSGVFGYVDLSEQAVFILSAGLDAIWESNNQR
NVLRANNQLTTHASTNQVHRFSVKEGMNSLSLNNVGCSSFKLELTSF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787487, Length=296, Percent_Identity=30.0675675675676, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=32.2033898305085, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=100, Percent_Identity=32, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=134, Percent_Identity=26.865671641791, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 41208; Mature: 41077

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEQATKKKEGEGNAPVEDLLLNKDILIVDDDPIFRSMIRAVLEAYSCNVKEANNGLEG
CCCHHHHHHCCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHCCCHHH
LQMLKHSLPDVLLCDLAMPILNGIEFVEEAVLEYPMLPIIVISGSGDMQDVAKVLRLGAK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCH
DFLVKPISDVSILIKSLSSALKLSEESSLRMQDFSSQWFRTSELDKSCNDELHWHLEYLQ
HHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EEPNVGRELLFELLPESEAQHANWKLSYRLLQSTDGMPLIFDYEWLLDGRLFFYLVDSHS
CCCCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCEEEEEEHHHCCCEEEEEEEECCC
GGENGVISCLLIRAFFNDFIREQQMSTNTISAMVASIEKGMGTMENSQAMSGVFGYVDLS
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEEECC
EQAVFILSAGLDAIWESNNQRNVLRANNQLTTHASTNQVHRFSVKEGMNSLSLNNVGCSS
CCEEEEEECCCHHHHCCCCCCCEEECCCEEEECCCCCHHEEEHHHHCCCCCCCCCCCCCC
FKLELTSF
EEEEEECC
>Mature Secondary Structure 
SVEQATKKKEGEGNAPVEDLLLNKDILIVDDDPIFRSMIRAVLEAYSCNVKEANNGLEG
CCHHHHHHCCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHCCCHHH
LQMLKHSLPDVLLCDLAMPILNGIEFVEEAVLEYPMLPIIVISGSGDMQDVAKVLRLGAK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCH
DFLVKPISDVSILIKSLSSALKLSEESSLRMQDFSSQWFRTSELDKSCNDELHWHLEYLQ
HHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EEPNVGRELLFELLPESEAQHANWKLSYRLLQSTDGMPLIFDYEWLLDGRLFFYLVDSHS
CCCCHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCEEEEEEHHHCCCEEEEEEEECCC
GGENGVISCLLIRAFFNDFIREQQMSTNTISAMVASIEKGMGTMENSQAMSGVFGYVDLS
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEEECC
EQAVFILSAGLDAIWESNNQRNVLRANNQLTTHASTNQVHRFSVKEGMNSLSLNNVGCSS
CCEEEEEECCCHHHHCCCCCCCEEECCCEEEECCCCCHHEEEHHHHCCCCCCCCCCCCCC
FKLELTSF
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]