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The map label for this gene is oppA [H]

Identifier: 59712204

GI number: 59712204

Start: 1790148

End: 1791812

Strand: Reverse

Name: oppA [H]

Synonym: VF_1597

Alternate gene names: 59712204

Gene position: 1791812-1790148 (Counterclockwise)

Preceding gene: 59712206

Following gene: 59712203

Centisome position: 61.84

GC content: 39.16

Gene sequence:

>1665_bases
ATGTATAAGAATAAAATTACACAAGCGATTTTGCTTGGTGGCCTGTCACTAGCACTTGCTGGCTGTGGAGATAAAACCGC
AGAGCAACCTGTCAAACAAACGAAACCTGCTGAAAAACCTGAATCAACTGAAGTCGTATATGCAGATGTACAAGAGTTGG
TTCGTGGTAATGGTACTGAGGTTGCGACTTTAGACCCTCATAAATCCCAAGGTGTTCCTGAATCTCACGTTATCCGTGAT
CTATTAGAAGGTCTTGTAAATCAAGATGCTGACGGTAATACGATCCCAGGTGTTGCAGAAAGTTGGGAAACAACAGATAA
CAAAAAATTTGTATTCCATTTACGTAAAGATGCTAAATGGTCAAATGGTGATCCTGTAACTGCTGATGATTTTGTATACA
GTTTCCAAAGAGCAGTCGATCCAATGACAGCATCACCATACTCTTGGTATATGGAATATACTAAGATGGCAAATGCAAAA
GACATCGTTGCTGGTAAGAAAGATAAGAGTGAACTTGGCGTTAAAGCGATTGATGCTCATACTCTAGAAGTTCAACTTGA
GACTGCTGTTCCTTATTTCGTAAAAATGATGGGCCACACGACAGTGAAGCCTGTTCATAAAGCAACAATTGAAAAATTTG
GAGATCAATGGACTAAACCAGGTAATTTTGTTGGTAATGGTGCATTCGTTGTTAATGACTGGGTTGTAAATGAACGCCTA
GAGCTTGTTCGTAATGAACAATACTGGGACAACAAAGATACTAAACTAACTAAGGTAACGTTCTTACCTATCGAAAATCA
GGTTTCAGAAATGAACCGCTTCTTATCTGGAGAGCTAGACTTTACTAATGAACTTCCAGTTGAACACTTTAAACGTCTAC
AAAAAGAAGAACCTGATTCAGTTTCTGTTGTAGGTAGCTTATGTACTTACTACTACTCGTTTAATACTAAGAAAAAACCG
TTTGATGATGTTCGTGTCCGTAAAGCGATTTCTTACGCTATTGACCGTTCTATTGTTTCAGACGTAATTCTAGGTCAAGG
CCAAAAACCAGCTTATTTCTTAACACCTGAGATTACTGCTGGCTTCAATCCTGAACTTCCTGCTTATGGCAAAATGACTC
AAGATGAACGTAATGCAGAAGCAAAACGTTTATTAACAGAAGCGGGCTTTGGTCCTGAGAATCCACTTAAATTTACATTG
CTGTACAACACTTCTGAAAACCATAAGAAGATCGCTGTGGCAGCTGGCTCTATGTGGAAAAAGACACTTGGGCTAGAAGT
TGTTTTAGAAAACCAAGAGTGGAAAACATACCTAGATTCTAAAGATCAAGGCCAGTTTGAAGTGGCTCGTGCGGGTTGGT
GTGGCGATTATAATGAAGCGTCAGCTTTCCTAACATTAATGGTAAGTAAAAATACAACTGGTGGCCAACATTACGGTAGT
GCAGAGTATGATGCGTTGATTGAAAAAGCATTGGCATCAACTTCTGAAGAAGAGCGTAATGCTATCTATTTAGAAGCTGA
GAAACTTCTAGCGAAAGATATGCCAATTGCTCCTATTTATCAATATGTTAAATCACGTTTACTATCCCCACAAGTAGGTG
GCTTCCCAACGGGCAATGCGGAAGAAAAAATCTACTCGAAAGACCTATATATCAAAGCTAAGTAA

Upstream 100 bases:

>100_bases
TTTTTTAGGCGTATTTAACGTTTTTTAGATTTAAATGATTGGCGAGTCGTTTTGCCCGAAGAATGTCATGGATGCAAATT
GAATGTATTGGAGTTAATGC

Downstream 100 bases:

>100_bases
TTATTAGCAAAATAAAATTATAAAAAATGTCACTACACGCAGGATCGCGTGTAGTGACTAGATCCATCTTTTAATATTTT
TTGTCACAGACTGGAAGAGT

Product: oligopeptide-binding protein OppA

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MYKNKITQAILLGGLSLALAGCGDKTAEQPVKQTKPAEKPESTEVVYADVQELVRGNGTEVATLDPHKSQGVPESHVIRD
LLEGLVNQDADGNTIPGVAESWETTDNKKFVFHLRKDAKWSNGDPVTADDFVYSFQRAVDPMTASPYSWYMEYTKMANAK
DIVAGKKDKSELGVKAIDAHTLEVQLETAVPYFVKMMGHTTVKPVHKATIEKFGDQWTKPGNFVGNGAFVVNDWVVNERL
ELVRNEQYWDNKDTKLTKVTFLPIENQVSEMNRFLSGELDFTNELPVEHFKRLQKEEPDSVSVVGSLCTYYYSFNTKKKP
FDDVRVRKAISYAIDRSIVSDVILGQGQKPAYFLTPEITAGFNPELPAYGKMTQDERNAEAKRLLTEAGFGPENPLKFTL
LYNTSENHKKIAVAAGSMWKKTLGLEVVLENQEWKTYLDSKDQGQFEVARAGWCGDYNEASAFLTLMVSKNTTGGQHYGS
AEYDALIEKALASTSEEERNAIYLEAEKLLAKDMPIAPIYQYVKSRLLSPQVGGFPTGNAEEKIYSKDLYIKAK

Sequences:

>Translated_554_residues
MYKNKITQAILLGGLSLALAGCGDKTAEQPVKQTKPAEKPESTEVVYADVQELVRGNGTEVATLDPHKSQGVPESHVIRD
LLEGLVNQDADGNTIPGVAESWETTDNKKFVFHLRKDAKWSNGDPVTADDFVYSFQRAVDPMTASPYSWYMEYTKMANAK
DIVAGKKDKSELGVKAIDAHTLEVQLETAVPYFVKMMGHTTVKPVHKATIEKFGDQWTKPGNFVGNGAFVVNDWVVNERL
ELVRNEQYWDNKDTKLTKVTFLPIENQVSEMNRFLSGELDFTNELPVEHFKRLQKEEPDSVSVVGSLCTYYYSFNTKKKP
FDDVRVRKAISYAIDRSIVSDVILGQGQKPAYFLTPEITAGFNPELPAYGKMTQDERNAEAKRLLTEAGFGPENPLKFTL
LYNTSENHKKIAVAAGSMWKKTLGLEVVLENQEWKTYLDSKDQGQFEVARAGWCGDYNEASAFLTLMVSKNTTGGQHYGS
AEYDALIEKALASTSEEERNAIYLEAEKLLAKDMPIAPIYQYVKSRLLSPQVGGFPTGNAEEKIYSKDLYIKAK
>Mature_554_residues
MYKNKITQAILLGGLSLALAGCGDKTAEQPVKQTKPAEKPESTEVVYADVQELVRGNGTEVATLDPHKSQGVPESHVIRD
LLEGLVNQDADGNTIPGVAESWETTDNKKFVFHLRKDAKWSNGDPVTADDFVYSFQRAVDPMTASPYSWYMEYTKMANAK
DIVAGKKDKSELGVKAIDAHTLEVQLETAVPYFVKMMGHTTVKPVHKATIEKFGDQWTKPGNFVGNGAFVVNDWVVNERL
ELVRNEQYWDNKDTKLTKVTFLPIENQVSEMNRFLSGELDFTNELPVEHFKRLQKEEPDSVSVVGSLCTYYYSFNTKKKP
FDDVRVRKAISYAIDRSIVSDVILGQGQKPAYFLTPEITAGFNPELPAYGKMTQDERNAEAKRLLTEAGFGPENPLKFTL
LYNTSENHKKIAVAAGSMWKKTLGLEVVLENQEWKTYLDSKDQGQFEVARAGWCGDYNEASAFLTLMVSKNTTGGQHYGS
AEYDALIEKALASTSEEERNAIYLEAEKLLAKDMPIAPIYQYVKSRLLSPQVGGFPTGNAEEKIYSKDLYIKAK

Specific function: This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=508, Percent_Identity=52.1653543307087, Blast_Score=563, Evalue=1e-162,
Organism=Escherichia coli, GI87081878, Length=515, Percent_Identity=50.0970873786408, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI1789397, Length=505, Percent_Identity=42.7722772277228, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1787762, Length=513, Percent_Identity=25.1461988304094, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1789966, Length=476, Percent_Identity=25.2100840336134, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787052, Length=491, Percent_Identity=23.2179226069246, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1789887, Length=511, Percent_Identity=24.26614481409, Blast_Score=108, Evalue=9e-25,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61966; Mature: 61966

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKNKITQAILLGGLSLALAGCGDKTAEQPVKQTKPAEKPESTEVVYADVQELVRGNGTE
CCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHCCCCCE
VATLDPHKSQGVPESHVIRDLLEGLVNQDADGNTIPGVAESWETTDNKKFVFHLRKDAKW
EEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
SNGDPVTADDFVYSFQRAVDPMTASPYSWYMEYTKMANAKDIVAGKKDKSELGVKAIDAH
CCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCHHHCCEEEECCE
TLEVQLETAVPYFVKMMGHTTVKPVHKATIEKFGDQWTKPGNFVGNGAFVVNDWVVNERL
EEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEECCCEEEEECHHHHHHH
ELVRNEQYWDNKDTKLTKVTFLPIENQVSEMNRFLSGELDFTNELPVEHFKRLQKEEPDS
HHHHCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCH
VSVVGSLCTYYYSFNTKKKPFDDVRVRKAISYAIDRSIVSDVILGQGQKPAYFLTPEITA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
GFNPELPAYGKMTQDERNAEAKRLLTEAGFGPENPLKFTLLYNTSENHKKIAVAAGSMWK
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEECCHHHH
KTLGLEVVLENQEWKTYLDSKDQGQFEVARAGWCGDYNEASAFLTLMVSKNTTGGQHYGS
HHCCEEEEEECCCHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCC
AEYDALIEKALASTSEEERNAIYLEAEKLLAKDMPIAPIYQYVKSRLLSPQVGGFPTGNA
HHHHHHHHHHHHCCCHHHCCEEEEEHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
EEKIYSKDLYIKAK
HHHEECCCEEEEEC
>Mature Secondary Structure
MYKNKITQAILLGGLSLALAGCGDKTAEQPVKQTKPAEKPESTEVVYADVQELVRGNGTE
CCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHCCCCCE
VATLDPHKSQGVPESHVIRDLLEGLVNQDADGNTIPGVAESWETTDNKKFVFHLRKDAKW
EEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
SNGDPVTADDFVYSFQRAVDPMTASPYSWYMEYTKMANAKDIVAGKKDKSELGVKAIDAH
CCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCHHHCCEEEECCE
TLEVQLETAVPYFVKMMGHTTVKPVHKATIEKFGDQWTKPGNFVGNGAFVVNDWVVNERL
EEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEECCCEEEEECHHHHHHH
ELVRNEQYWDNKDTKLTKVTFLPIENQVSEMNRFLSGELDFTNELPVEHFKRLQKEEPDS
HHHHCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCH
VSVVGSLCTYYYSFNTKKKPFDDVRVRKAISYAIDRSIVSDVILGQGQKPAYFLTPEITA
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
GFNPELPAYGKMTQDERNAEAKRLLTEAGFGPENPLKFTLLYNTSENHKKIAVAAGSMWK
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEECCHHHH
KTLGLEVVLENQEWKTYLDSKDQGQFEVARAGWCGDYNEASAFLTLMVSKNTTGGQHYGS
HHCCEEEEEECCCHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCCC
AEYDALIEKALASTSEEERNAIYLEAEKLLAKDMPIAPIYQYVKSRLLSPQVGGFPTGNA
HHHHHHHHHHHHCCCHHHCCEEEEEHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
EEKIYSKDLYIKAK
HHHEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2821267; 3525163; 11677609; 8202710; 8747465; 10422831; 10438628 [H]