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The map label for this gene is tdk

Identifier: 59712206

GI number: 59712206

Start: 1795052

End: 1795630

Strand: Reverse

Name: tdk

Synonym: VF_1599

Alternate gene names: 59712206

Gene position: 1795630-1795052 (Counterclockwise)

Preceding gene: 59712207

Following gene: 59712204

Centisome position: 61.97

GC content: 36.44

Gene sequence:

>579_bases
GTGGCACAAATGTATTTTTATTACTCTGCAATGAATGCGGGGAAATCAACAACACTTCTTCAATCATCATTTAATTATCA
AGAACGCGGTATGAATCCTGCTATTTTTACAGCCGCGATTGATGATCGTTATGGTGTTGGTAAAGTAAGTTCTCGAATTG
GTTTACATGCAGAAGCACACTTGTTTAATAAAGAAACGAATGTATTCGACGCAATTAAAGAGTTGCATGAAGCAGAAAAA
CTTCACTGTGTTTTAATTGATGAATGTCAGTTTTTAACGAAAGAACAAGTATATCAACTGACAGAAGTCGTTGATAAATT
AAATATCCCAGCACTTTGTTATGGCTTACGAACTGACTTTTTAGGAGAGTTATTTGAGGGAAGTAAATATTTACTTTCTT
GGGCTGATAAATTGGTTGAATTAAAAACCATTTGTCACTGTGGACGTAAAGCAAACATGGTGATTCGTACGGATGAGCAT
GGTGTAGCCATTGCAGATGGTGATCAAGTTGCTATCGGTGGTAATGAGTTGTACGTTTCAGTATGTCGACGCCATTATAA
AGAAGCGCTAGGTAAATAG

Upstream 100 bases:

>100_bases
AACGTGGCGTCGTAAGTAATACAAACAGTTTTATATAAAGGGCTGGTATTTCCAGCCTTTTTTATTACCAAATTTTTAAA
CTTTAATAGAGGACACATTT

Downstream 100 bases:

>100_bases
AATTTACTTAATTAGTTTGTACGGTTTTAAAAGAAAGACCAAGTTCAGATAAGTGAGCTTGGTCTTTTTATTTTTAAATG
AAAGGATTAGTTACAAGTAG

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MAQMYFYYSAMNAGKSTTLLQSSFNYQERGMNPAIFTAAIDDRYGVGKVSSRIGLHAEAHLFNKETNVFDAIKELHEAEK
LHCVLIDECQFLTKEQVYQLTEVVDKLNIPALCYGLRTDFLGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEH
GVAIADGDQVAIGGNELYVSVCRRHYKEALGK

Sequences:

>Translated_192_residues
MAQMYFYYSAMNAGKSTTLLQSSFNYQERGMNPAIFTAAIDDRYGVGKVSSRIGLHAEAHLFNKETNVFDAIKELHEAEK
LHCVLIDECQFLTKEQVYQLTEVVDKLNIPALCYGLRTDFLGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEH
GVAIADGDQVAIGGNELYVSVCRRHYKEALGK
>Mature_191_residues
AQMYFYYSAMNAGKSTTLLQSSFNYQERGMNPAIFTAAIDDRYGVGKVSSRIGLHAEAHLFNKETNVFDAIKELHEAEKL
HCVLIDECQFLTKEQVYQLTEVVDKLNIPALCYGLRTDFLGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEHG
VAIADGDQVAIGGNELYVSVCRRHYKEALGK

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=70.5263157894737, Blast_Score=296, Evalue=5e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_VIBF1 (Q5E4F2)

Other databases:

- EMBL:   CP000020
- RefSeq:   YP_204982.1
- ProteinModelPortal:   Q5E4F2
- STRING:   Q5E4F2
- GeneID:   3278805
- GenomeReviews:   CP000020_GR
- KEGG:   vfi:VF_1599
- NMPDR:   fig|312309.3.peg.1599
- eggNOG:   COG1435
- HOGENOM:   HBG522108
- OMA:   FRYGAMN
- PhylomeDB:   Q5E4F2
- ProtClustDB:   PRK04296
- BioCyc:   VFIS312309:VF1599-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 21640; Mature: 21509

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 88-88

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMYFYYSAMNAGKSTTLLQSSFNYQERGMNPAIFTAAIDDRYGVGKVSSRIGLHAEAH
CCEEEEEEEECCCCCCHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCHHHH
LFNKETNVFDAIKELHEAEKLHCVLIDECQFLTKEQVYQLTEVVDKLNIPALCYGLRTDF
HHCCCCHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEHGVAIADGDQVAIGGNELYVS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCEEEECCCHHHHH
VCRRHYKEALGK
HHHHHHHHHHCC
>Mature Secondary Structure 
AQMYFYYSAMNAGKSTTLLQSSFNYQERGMNPAIFTAAIDDRYGVGKVSSRIGLHAEAH
CEEEEEEEECCCCCCHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCHHHH
LFNKETNVFDAIKELHEAEKLHCVLIDECQFLTKEQVYQLTEVVDKLNIPALCYGLRTDF
HHCCCCHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LGELFEGSKYLLSWADKLVELKTICHCGRKANMVIRTDEHGVAIADGDQVAIGGNELYVS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCEEEECCCHHHHH
VCRRHYKEALGK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA