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The map label for this gene is hscA [H]

Identifier: 59712125

GI number: 59712125

Start: 1694369

End: 1697185

Strand: Direct

Name: hscA [H]

Synonym: VF_1518

Alternate gene names: 59712125

Gene position: 1694369-1697185 (Clockwise)

Preceding gene: 59712124

Following gene: 172087715

Centisome position: 58.48

GC content: 41.75

Gene sequence:

>2817_bases
ATGAGTTCTTCTAATCGCTATTTAATTGGTATCGATCTTGGTACTACTCACACCGTTGTTGCTTATACTGATATTTCTCT
TGGTATTGAAACTAGCCCAATTGAAATCTTCAATATCGACCAATTAATTGGACCGGGTGAAGTGGCTCGTAAACCCCTAC
TTCCATCATTTCGTTACCATGCATCACAAAGTCAAATCACTGAAAATGATCTGACACTGCCTTGGAATGTAAAAGCAATT
GAAGGTGAGATAAAGAACGCCATTATTGGTGAGTGGGCTCGTGAATTAGGGTCAAAAGTAGAAGGTCGCCAAGTCGTAAG
TGCTAAGAGTTGGTTATCTCATACTAAAGTTGATCGCACCTCCAATATTCTTCCTTGGGCTGGCGCTGATGATGTCGAAA
AAGTCTCACCTATTGTTGCCAGTGCTAGTTATTTAAACCATGTACGCCAATCGTGGAATTACCACCACCCAGATGCCCCA
ATGGAGCTTCAGGAAGTGGTTGTTACCGTACCGGCATCTTTTGATGAAAGTGCACGCTCATTTACGATTGAGGCTGCAAA
ACTGGCAGGCCTTGATAAAATCATCCTATTAGAAGAGCCACAAGCGGTGTGTTACGACTGGTATCATCATCATCAAGATA
CGGCAAAAGAGATTTTAAAAACCATCCCACTAATGGTGGTATGCGATGTTGGCGGTGGTACAACCGATTTAAGCTTAATT
CAAGCGCGTTTTAATAAAGACGAATTAGCACTTGATCGCATTGGCGTGGGCGATCACTTAATGCTAGGTGGCGATAACAT
TGATTTAGCGCTAGCACATTTAGCTGAACAGCGCTTAGATAGCGGTAAAAAAATGACGGCAGCCGCGTTAACCAAGCTTA
TTCAACAAACACGTAAAACAAAAGAGCGTTTGTTATCTGCTAATGCTCCCGAATCAGGCCACATTACCCTACTTGGATCT
GGTTCTAAATTATTAGGTGGCAGTCGTAAAGTCGAGTTGACCAAAGAAGAAGTTCATCAAATTGCACTGGATGGATTCTT
ACCACTGACTGACTTTAATGACCGTCCAAATCAACGTCAAACTGCTGTTGTTGAATTTGGCTTACCTTACGCTTCAGATC
CTGCTATCAGTAAACACTTAGCTCAGTTCTTAGATAATCATAAAGAAGTATCAGCAAAAGCATTAGGTTGGGATGATGCT
GAATTGGCTAATCACGAGGACCGTGCAATACCTGTAGGTTTGCTGCTTAATGGCGGTGTTTTTAATAGCCCATTATTGGC
TGAACGTTCTCTTCAACTACTTAACAACTGGAAAGGTGACACTGTCACTCAACTATCAAACCCTCATCCAGATCTAGCGG
TTGCTTATGGCGCAGTTGCTTATGGCAAGGCACGTCATGGTGCACAATTAAAGATCGGTGGAGGCTCCGCTCGTTCATTC
TATTTACAGCTAGAAGAGAAAAACAAACAACCTCAAGGTCTGTGTTTATTGGCTAAAGGCAGTGAGGAAGGTGAAGAGAT
CCGCATGACGAGTCGTCGTTTCTCGTTAACCTTGGGAGAACCTGTTCGTTTTAATCTACTTTCTACAACAAAAGATCAAC
TTGCAACCTCGGGTATGATCACTGAATTAGCTGATTCTAGCTTTGTTAGCCTACCTCCTTATGTGGTAACACTAGAATCT
AGTAAATCAAAAGATGAACTGCATGCAAACCAAAAAGATCGCGTTGAAGTAACCTTAGCTTGCCAATTTACAGAAGTCGG
CACCATTAAAATTGAATGTGTTTCTGTTGAGGACGATTCACAGCGTTGGTTGGTTGAATTTGAAGTACGTAATCAGGCGT
CTAATAAAAGCGCTAACCTTGCGGATCAAGTTAGCCTTCCCCCTCGCCTACCTAATGCTATAGCAAGCATTAAAGAGGCT
TATGGTGGCAGCAAACAAAATCCAAATGCCATCAAAGCTTTTAATAAAAATATTGAAAAGCTAATTGGTAAGCGTGAATC
ATGGGATCTTATTACGTCTCGTGAACTTGCAACAGCATTACTTGATAGTAAAAAACGTCGTCGTCGCTCTGACAAACACG
AACAAAATTGGTTAAAAATGACGGGGTTCGCTTTACGCCCCGGTTTTGGCTACCCTGCTGATGAATGGAAGATATCTCAA
GCATGGGAAACCTATCAACAAGGTATTCAATTTGAATCGAAACAATCTTGGAACGATTGGTGGACATTCTGGCGTCGGAT
CTCTGGTGGTTTAAATCAAGAGCAACAAGAAACCATTTTAGCTGATATGGCGAAATACCTGCATCCTGGTTCTTTACGTA
ACCCAAAAACATTAGAAGAAGCCAGTAACAAAAGTTATGAAGCTATGGTACGACTTGCCGCAGCACTCGAACATTTGGAC
GTAGAAGATAAAATGCTGATTGCATCTTGGGTATTAGGTCATGCTAAAAATGGAAATCAACCGCAAGTACATTGGTGGGC
ATTAGGCCGAATTTGTTCACGTTCACCATTCTATGGAAGCCAGCATAATTTAGTTCCACCAAGCCAAATATCTCAATGGC
TACCAACATTATTAGAGCAAGATTGGAAAGAACAGCCCATGGCTGGTTTTGCCGCAGTAATGATGGCTCGCTTAACCGGT
GATAGAACCCTTGATGTTTCAGATGAATATCGAGAAAAAATCATCGAAAAATTGAAAAAAGATCGCTGCCCACAAAGCTG
GATTGAATTAGTATCAAGCCAACAAGCATTAACAGAAGCAGACTCTAAACGCTTATTTGGTGACGCATTACCCGCAGGCT
TACGTTTAATTAATTAG

Upstream 100 bases:

>100_bases
TTTTGCTGTTGCCTTCTTATACCAATGTAACTAATTAGATGTTCATTATTAATATTGATATTACTAACAGCTACAAGACT
AACATTACGTCGGGGTTTTT

Downstream 100 bases:

>100_bases
ACAGATTCTCATTAATGCTTTAATTAGTTATATGAGAAATGAATATCTCTGATGAAAAATTGCGCACCTCTGTCAAAGGT
GTGCAAACAACATCTTATTC

Product: DnaK-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 938; Mature: 937

Protein sequence:

>938_residues
MSSSNRYLIGIDLGTTHTVVAYTDISLGIETSPIEIFNIDQLIGPGEVARKPLLPSFRYHASQSQITENDLTLPWNVKAI
EGEIKNAIIGEWARELGSKVEGRQVVSAKSWLSHTKVDRTSNILPWAGADDVEKVSPIVASASYLNHVRQSWNYHHPDAP
MELQEVVVTVPASFDESARSFTIEAAKLAGLDKIILLEEPQAVCYDWYHHHQDTAKEILKTIPLMVVCDVGGGTTDLSLI
QARFNKDELALDRIGVGDHLMLGGDNIDLALAHLAEQRLDSGKKMTAAALTKLIQQTRKTKERLLSANAPESGHITLLGS
GSKLLGGSRKVELTKEEVHQIALDGFLPLTDFNDRPNQRQTAVVEFGLPYASDPAISKHLAQFLDNHKEVSAKALGWDDA
ELANHEDRAIPVGLLLNGGVFNSPLLAERSLQLLNNWKGDTVTQLSNPHPDLAVAYGAVAYGKARHGAQLKIGGGSARSF
YLQLEEKNKQPQGLCLLAKGSEEGEEIRMTSRRFSLTLGEPVRFNLLSTTKDQLATSGMITELADSSFVSLPPYVVTLES
SKSKDELHANQKDRVEVTLACQFTEVGTIKIECVSVEDDSQRWLVEFEVRNQASNKSANLADQVSLPPRLPNAIASIKEA
YGGSKQNPNAIKAFNKNIEKLIGKRESWDLITSRELATALLDSKKRRRRSDKHEQNWLKMTGFALRPGFGYPADEWKISQ
AWETYQQGIQFESKQSWNDWWTFWRRISGGLNQEQQETILADMAKYLHPGSLRNPKTLEEASNKSYEAMVRLAAALEHLD
VEDKMLIASWVLGHAKNGNQPQVHWWALGRICSRSPFYGSQHNLVPPSQISQWLPTLLEQDWKEQPMAGFAAVMMARLTG
DRTLDVSDEYREKIIEKLKKDRCPQSWIELVSSQQALTEADSKRLFGDALPAGLRLIN

Sequences:

>Translated_938_residues
MSSSNRYLIGIDLGTTHTVVAYTDISLGIETSPIEIFNIDQLIGPGEVARKPLLPSFRYHASQSQITENDLTLPWNVKAI
EGEIKNAIIGEWARELGSKVEGRQVVSAKSWLSHTKVDRTSNILPWAGADDVEKVSPIVASASYLNHVRQSWNYHHPDAP
MELQEVVVTVPASFDESARSFTIEAAKLAGLDKIILLEEPQAVCYDWYHHHQDTAKEILKTIPLMVVCDVGGGTTDLSLI
QARFNKDELALDRIGVGDHLMLGGDNIDLALAHLAEQRLDSGKKMTAAALTKLIQQTRKTKERLLSANAPESGHITLLGS
GSKLLGGSRKVELTKEEVHQIALDGFLPLTDFNDRPNQRQTAVVEFGLPYASDPAISKHLAQFLDNHKEVSAKALGWDDA
ELANHEDRAIPVGLLLNGGVFNSPLLAERSLQLLNNWKGDTVTQLSNPHPDLAVAYGAVAYGKARHGAQLKIGGGSARSF
YLQLEEKNKQPQGLCLLAKGSEEGEEIRMTSRRFSLTLGEPVRFNLLSTTKDQLATSGMITELADSSFVSLPPYVVTLES
SKSKDELHANQKDRVEVTLACQFTEVGTIKIECVSVEDDSQRWLVEFEVRNQASNKSANLADQVSLPPRLPNAIASIKEA
YGGSKQNPNAIKAFNKNIEKLIGKRESWDLITSRELATALLDSKKRRRRSDKHEQNWLKMTGFALRPGFGYPADEWKISQ
AWETYQQGIQFESKQSWNDWWTFWRRISGGLNQEQQETILADMAKYLHPGSLRNPKTLEEASNKSYEAMVRLAAALEHLD
VEDKMLIASWVLGHAKNGNQPQVHWWALGRICSRSPFYGSQHNLVPPSQISQWLPTLLEQDWKEQPMAGFAAVMMARLTG
DRTLDVSDEYREKIIEKLKKDRCPQSWIELVSSQQALTEADSKRLFGDALPAGLRLIN
>Mature_937_residues
SSSNRYLIGIDLGTTHTVVAYTDISLGIETSPIEIFNIDQLIGPGEVARKPLLPSFRYHASQSQITENDLTLPWNVKAIE
GEIKNAIIGEWARELGSKVEGRQVVSAKSWLSHTKVDRTSNILPWAGADDVEKVSPIVASASYLNHVRQSWNYHHPDAPM
ELQEVVVTVPASFDESARSFTIEAAKLAGLDKIILLEEPQAVCYDWYHHHQDTAKEILKTIPLMVVCDVGGGTTDLSLIQ
ARFNKDELALDRIGVGDHLMLGGDNIDLALAHLAEQRLDSGKKMTAAALTKLIQQTRKTKERLLSANAPESGHITLLGSG
SKLLGGSRKVELTKEEVHQIALDGFLPLTDFNDRPNQRQTAVVEFGLPYASDPAISKHLAQFLDNHKEVSAKALGWDDAE
LANHEDRAIPVGLLLNGGVFNSPLLAERSLQLLNNWKGDTVTQLSNPHPDLAVAYGAVAYGKARHGAQLKIGGGSARSFY
LQLEEKNKQPQGLCLLAKGSEEGEEIRMTSRRFSLTLGEPVRFNLLSTTKDQLATSGMITELADSSFVSLPPYVVTLESS
KSKDELHANQKDRVEVTLACQFTEVGTIKIECVSVEDDSQRWLVEFEVRNQASNKSANLADQVSLPPRLPNAIASIKEAY
GGSKQNPNAIKAFNKNIEKLIGKRESWDLITSRELATALLDSKKRRRRSDKHEQNWLKMTGFALRPGFGYPADEWKISQA
WETYQQGIQFESKQSWNDWWTFWRRISGGLNQEQQETILADMAKYLHPGSLRNPKTLEEASNKSYEAMVRLAAALEHLDV
EDKMLIASWVLGHAKNGNQPQVHWWALGRICSRSPFYGSQHNLVPPSQISQWLPTLLEQDWKEQPMAGFAAVMMARLTGD
RTLDVSDEYREKIIEKLKKDRCPQSWIELVSSQQALTEADSKRLFGDALPAGLRLIN

Specific function: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by hscB [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126
- InterPro:   IPR010236 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 104411; Mature: 104280

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSNRYLIGIDLGTTHTVVAYTDISLGIETSPIEIFNIDQLIGPGEVARKPLLPSFRYH
CCCCCCEEEEEECCCCEEEEEEEEEEECCCCCCEEEEEHHHHCCCHHHHHCCCCCCHHHC
ASQSQITENDLTLPWNVKAIEGEIKNAIIGEWARELGSKVEGRQVVSAKSWLSHTKVDRT
CCHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
SNILPWAGADDVEKVSPIVASASYLNHVRQSWNYHHPDAPMELQEVVVTVPASFDESARS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEECCCCCCCCCCE
FTIEAAKLAGLDKIILLEEPQAVCYDWYHHHQDTAKEILKTIPLMVVCDVGGGTTDLSLI
EEEEHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHH
QARFNKDELALDRIGVGDHLMLGGDNIDLALAHLAEQRLDSGKKMTAAALTKLIQQTRKT
HHHCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KERLLSANAPESGHITLLGSGSKLLGGSRKVELTKEEVHQIALDGFLPLTDFNDRPNQRQ
HHHHHCCCCCCCCCEEEEECCCHHCCCCCEEEECHHHHHHHHHHCCEECCCCCCCCCCCC
TAVVEFGLPYASDPAISKHLAQFLDNHKEVSAKALGWDDAELANHEDRAIPVGLLLNGGV
EEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCHHHCCCCCCCEEEEEEEECCC
FNSPLLAERSLQLLNNWKGDTVTQLSNPHPDLAVAYGAVAYGKARHGAQLKIGGGSARSF
CCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCEEHHHHHHHCCCCCCCEEEECCCCCEEE
YLQLEEKNKQPQGLCLLAKGSEEGEEIRMTSRRFSLTLGEPVRFNLLSTTKDQLATSGMI
EEEEECCCCCCCCEEEEECCCCCCCHHEEEHHEEEEEECCCEEEEEECCCHHHHHHCCHH
TELADSSFVSLPPYVVTLESSKSKDELHANQKDRVEVTLACQFTEVGTIKIECVSVEDDS
HHHCCCCCEECCCEEEEECCCCCCHHHCCCCCCCEEEEEEEEEEECCEEEEEEEEECCCC
QRWLVEFEVRNQASNKSANLADQVSLPPRLPNAIASIKEAYGGSKQNPNAIKAFNKNIEK
CEEEEEEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LIGKRESWDLITSRELATALLDSKKRRRRSDKHEQNWLKMTGFALRPGFGYPADEWKISQ
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCCCCCCHHH
AWETYQQGIQFESKQSWNDWWTFWRRISGGLNQEQQETILADMAKYLHPGSLRNPKTLEE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
ASNKSYEAMVRLAAALEHLDVEDKMLIASWVLGHAKNGNQPQVHWWALGRICSRSPFYGS
HCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCCCCCCC
QHNLVPPSQISQWLPTLLEQDWKEQPMAGFAAVMMARLTGDRTLDVSDEYREKIIEKLKK
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHH
DRCPQSWIELVSSQQALTEADSKRLFGDALPAGLRLIN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure 
SSSNRYLIGIDLGTTHTVVAYTDISLGIETSPIEIFNIDQLIGPGEVARKPLLPSFRYH
CCCCCEEEEEECCCCEEEEEEEEEEECCCCCCEEEEEHHHHCCCHHHHHCCCCCCHHHC
ASQSQITENDLTLPWNVKAIEGEIKNAIIGEWARELGSKVEGRQVVSAKSWLSHTKVDRT
CCHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
SNILPWAGADDVEKVSPIVASASYLNHVRQSWNYHHPDAPMELQEVVVTVPASFDESARS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEECCCCCCCCCCE
FTIEAAKLAGLDKIILLEEPQAVCYDWYHHHQDTAKEILKTIPLMVVCDVGGGTTDLSLI
EEEEHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHH
QARFNKDELALDRIGVGDHLMLGGDNIDLALAHLAEQRLDSGKKMTAAALTKLIQQTRKT
HHHCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KERLLSANAPESGHITLLGSGSKLLGGSRKVELTKEEVHQIALDGFLPLTDFNDRPNQRQ
HHHHHCCCCCCCCCEEEEECCCHHCCCCCEEEECHHHHHHHHHHCCEECCCCCCCCCCCC
TAVVEFGLPYASDPAISKHLAQFLDNHKEVSAKALGWDDAELANHEDRAIPVGLLLNGGV
EEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCHHHCCCCCCCEEEEEEEECCC
FNSPLLAERSLQLLNNWKGDTVTQLSNPHPDLAVAYGAVAYGKARHGAQLKIGGGSARSF
CCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCEEHHHHHHHCCCCCCCEEEECCCCCEEE
YLQLEEKNKQPQGLCLLAKGSEEGEEIRMTSRRFSLTLGEPVRFNLLSTTKDQLATSGMI
EEEEECCCCCCCCEEEEECCCCCCCHHEEEHHEEEEEECCCEEEEEECCCHHHHHHCCHH
TELADSSFVSLPPYVVTLESSKSKDELHANQKDRVEVTLACQFTEVGTIKIECVSVEDDS
HHHCCCCCEECCCEEEEECCCCCCHHHCCCCCCCEEEEEEEEEEECCEEEEEEEEECCCC
QRWLVEFEVRNQASNKSANLADQVSLPPRLPNAIASIKEAYGGSKQNPNAIKAFNKNIEK
CEEEEEEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LIGKRESWDLITSRELATALLDSKKRRRRSDKHEQNWLKMTGFALRPGFGYPADEWKISQ
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCCCCCCCCCCCHHH
AWETYQQGIQFESKQSWNDWWTFWRRISGGLNQEQQETILADMAKYLHPGSLRNPKTLEE
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
ASNKSYEAMVRLAAALEHLDVEDKMLIASWVLGHAKNGNQPQVHWWALGRICSRSPFYGS
HCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCCCCCCC
QHNLVPPSQISQWLPTLLEQDWKEQPMAGFAAVMMARLTGDRTLDVSDEYREKIIEKLKK
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHH
DRCPQSWIELVSSQQALTEADSKRLFGDALPAGLRLIN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA