Click here to switch to the map view.

The map label for this gene is tcpI [H]

Identifier: 59712111

GI number: 59712111

Start: 1664907

End: 1666868

Strand: Direct

Name: tcpI [H]

Synonym: VF_1504

Alternate gene names: 59712111

Gene position: 1664907-1666868 (Clockwise)

Preceding gene: 59712110

Following gene: 59712112

Centisome position: 57.46

GC content: 36.24

Gene sequence:

>1962_bases
ATGAACCACTCCTTTATATTTAAACTATCGCTAAATAAACCTTTACTAGCGTTATTGCTTGCACCAGTTTTCACTTCTCT
TATTTTATTCGCTATCGTTGCTTTCTTAATTGACGCTCGCAATAATGAAGTTGAAGATAATATTATTCAAACCGCAGAAA
GAGCCGCTCTTGGTTCTGAAATTATGCAACTACGCCACAATTGGCAAGAAATCCGTGTAAAAAATAGAGATACAATGTCT
GAAAATGGACAAGCTATGCAAGAGCAACAAAAAGAATTACAAAAGGCATTTGTATCCACAAACACCCATATCAAAGAGAA
CATTCTGACATCAAAGGTCTTAAGTGATGCAGGTAAGTCCGATATAGCTAATTTACAAAAAACATTAATTGATTACGAAA
AAAGTATTAATACTTCAGTAAAAATATTAACTGAGTTATATGATGCTCAAATCGCCACTCCTATTTTTTGGCAACCAATG
GTTGAAGTACTTACTTTTATTGGTCCTATATATAATGGTTCTGCATCAGATTGGGAAAAAGAGCGCATTACTTTTACCAC
TAACGTAGAGCGTTTTTATGACAGTTTAAGTCGAATGGTTAATGGTAGAGATTTGAGCGAACAAAAAACAGCAGAACAAT
ATCTTACTTCAATTACTTCTTTTTTAAGTCAATATAATAAATACCCTGAGGTTAAATACTTCACTGATAATGTTTTTGGT
TCATATTTATCTCTATACCAAGAAAGTATTAACACCTTAAAAGCAAACTCTGAGCAGTCTAAACTACGTGTAAAGATGGT
TGAAGATATTACTAATGTGATTTCAACTGTAAATGCACGTCAAGTTGAATTCACGCAAACACTAAATCAACGTTCTTTGA
ATGCAAGTAAAAATGTGGAAAACACTCAAATTTGGTCATGGCTTGGTGCTGCCCTACTTTCTACATTTATCGCCCTCTTA
CTTGCTCGTAATATTAATAATGTCTTAGCTGCAATTTCAAAAACAATTGCGGCAATGGCTAAACAAAATTTAGCGACATT
AACTAATTTATCAGGCACAAACGAGCTTGCGGTGCTTGCTACAAATCTAGATGCTTCAATTAAGAATATGGCCAATATGG
TTGGCTCTGTCAGAGAACAAAGTAATGATGTTGCTTCTTCTTCAACTGAACTTGCGTGTGTTATGACACAAAGCTCAAGC
AATGCTGAAGAACAAAGTGCGCAAATTGAACAAATTGCAGCTGCAGTCACTGAACTATCAGCCTCTTCAAACTTAGTGGC
TGATTCTGCGAAAAATACAGAATTACAAGCAACAGAAGCAGCAACACTGTGTGAATTAGGCCAAGAGATTGCTGAGCAAA
ATAAAACGCGTGCCGATGACTTAACCACTCAATTAAGTGAAACAGCATCGGTTGTAGAAAACTTACGTACTCACTGTGTA
AGTATTGAGGAAGTCGCAACGGTTATTAATAACATCTCAGAACAAACTAACTTACTAGCACTTAATGCAGCGATTGAAGC
AGCCCGTGCTGGTGAAATGGGACGAGGTTTTGCGGTTGTTGCCGATGAAGTTCGTAACCTTGCAGGGAAAACACAACAAT
CAACGGTTCACATTAAGAAGATCATTTCTGAATTGCAATCTTACTCATTAGATGCGACAGAAAAAGTAGACGGCTGTTTA
AACACGATTACCTTAACTCGTGAAACGTCAATTCAATCTTACGATCACTTAACGAACATCAACGCTGCAATTCAGTCTAT
TTACGGCAGCTCAACTGAAATGGCTTCAGCTGCGCTACAACAATCAAATGCGGTTGAAGAAATTACAGGAACGGTTATTG
GTATTAAAGAAATCATTAATCAAAACGTAACTGGTATTGAAGAATCAAGTAAAGCGTCAAACTTCTTATCAGAGCTAGCA
GAACAACAACGCTCACAACTTGAGCTGTTTAAAATTAAATAA

Upstream 100 bases:

>100_bases
GCTTTACAAAAATGCACTTATTTATATAACAAAATAACACTATTTTTGAATATATATCAAATAATGATATTTATTTGCAT
ATACATTCAGGAGAGCAAAC

Downstream 100 bases:

>100_bases
AATCACTACCCTAATCTAGCCATGGAAAGTTTAAAGCTTTCCATGGTTTATTTAATTTTCACCTCTATTCCCCTTTCCTC
ACTATATAAATCGTTTTATT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MNHSFIFKLSLNKPLLALLLAPVFTSLILFAIVAFLIDARNNEVEDNIIQTAERAALGSEIMQLRHNWQEIRVKNRDTMS
ENGQAMQEQQKELQKAFVSTNTHIKENILTSKVLSDAGKSDIANLQKTLIDYEKSINTSVKILTELYDAQIATPIFWQPM
VEVLTFIGPIYNGSASDWEKERITFTTNVERFYDSLSRMVNGRDLSEQKTAEQYLTSITSFLSQYNKYPEVKYFTDNVFG
SYLSLYQESINTLKANSEQSKLRVKMVEDITNVISTVNARQVEFTQTLNQRSLNASKNVENTQIWSWLGAALLSTFIALL
LARNINNVLAAISKTIAAMAKQNLATLTNLSGTNELAVLATNLDASIKNMANMVGSVREQSNDVASSSTELACVMTQSSS
NAEEQSAQIEQIAAAVTELSASSNLVADSAKNTELQATEAATLCELGQEIAEQNKTRADDLTTQLSETASVVENLRTHCV
SIEEVATVINNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRNLAGKTQQSTVHIKKIISELQSYSLDATEKVDGCL
NTITLTRETSIQSYDHLTNINAAIQSIYGSSTEMASAALQQSNAVEEITGTVIGIKEIINQNVTGIEESSKASNFLSELA
EQQRSQLELFKIK

Sequences:

>Translated_653_residues
MNHSFIFKLSLNKPLLALLLAPVFTSLILFAIVAFLIDARNNEVEDNIIQTAERAALGSEIMQLRHNWQEIRVKNRDTMS
ENGQAMQEQQKELQKAFVSTNTHIKENILTSKVLSDAGKSDIANLQKTLIDYEKSINTSVKILTELYDAQIATPIFWQPM
VEVLTFIGPIYNGSASDWEKERITFTTNVERFYDSLSRMVNGRDLSEQKTAEQYLTSITSFLSQYNKYPEVKYFTDNVFG
SYLSLYQESINTLKANSEQSKLRVKMVEDITNVISTVNARQVEFTQTLNQRSLNASKNVENTQIWSWLGAALLSTFIALL
LARNINNVLAAISKTIAAMAKQNLATLTNLSGTNELAVLATNLDASIKNMANMVGSVREQSNDVASSSTELACVMTQSSS
NAEEQSAQIEQIAAAVTELSASSNLVADSAKNTELQATEAATLCELGQEIAEQNKTRADDLTTQLSETASVVENLRTHCV
SIEEVATVINNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRNLAGKTQQSTVHIKKIISELQSYSLDATEKVDGCL
NTITLTRETSIQSYDHLTNINAAIQSIYGSSTEMASAALQQSNAVEEITGTVIGIKEIINQNVTGIEESSKASNFLSELA
EQQRSQLELFKIK
>Mature_653_residues
MNHSFIFKLSLNKPLLALLLAPVFTSLILFAIVAFLIDARNNEVEDNIIQTAERAALGSEIMQLRHNWQEIRVKNRDTMS
ENGQAMQEQQKELQKAFVSTNTHIKENILTSKVLSDAGKSDIANLQKTLIDYEKSINTSVKILTELYDAQIATPIFWQPM
VEVLTFIGPIYNGSASDWEKERITFTTNVERFYDSLSRMVNGRDLSEQKTAEQYLTSITSFLSQYNKYPEVKYFTDNVFG
SYLSLYQESINTLKANSEQSKLRVKMVEDITNVISTVNARQVEFTQTLNQRSLNASKNVENTQIWSWLGAALLSTFIALL
LARNINNVLAAISKTIAAMAKQNLATLTNLSGTNELAVLATNLDASIKNMANMVGSVREQSNDVASSSTELACVMTQSSS
NAEEQSAQIEQIAAAVTELSASSNLVADSAKNTELQATEAATLCELGQEIAEQNKTRADDLTTQLSETASVVENLRTHCV
SIEEVATVINNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRNLAGKTQQSTVHIKKIISELQSYSLDATEKVDGCL
NTITLTRETSIQSYDHLTNINAAIQSIYGSSTEMASAALQQSNAVEEITGTVIGIKEIINQNVTGIEESSKASNFLSELA
EQQRSQLELFKIK

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=383, Percent_Identity=28.7206266318538, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788195, Length=296, Percent_Identity=31.4189189189189, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788194, Length=325, Percent_Identity=30.7692307692308, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI2367378, Length=291, Percent_Identity=31.2714776632302, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1789453, Length=287, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71859; Mature: 71859

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHSFIFKLSLNKPLLALLLAPVFTSLILFAIVAFLIDARNNEVEDNIIQTAERAALGSE
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IMQLRHNWQEIRVKNRDTMSENGQAMQEQQKELQKAFVSTNTHIKENILTSKVLSDAGKS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
DIANLQKTLIDYEKSINTSVKILTELYDAQIATPIFWQPMVEVLTFIGPIYNGSASDWEK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
ERITFTTNVERFYDSLSRMVNGRDLSEQKTAEQYLTSITSFLSQYNKYPEVKYFTDNVFG
CCEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
SYLSLYQESINTLKANSEQSKLRVKMVEDITNVISTVNARQVEFTQTLNQRSLNASKNVE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
NTQIWSWLGAALLSTFIALLLARNINNVLAAISKTIAAMAKQNLATLTNLSGTNELAVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
TNLDASIKNMANMVGSVREQSNDVASSSTELACVMTQSSSNAEEQSAQIEQIAAAVTELS
ECCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
ASSNLVADSAKNTELQATEAATLCELGQEIAEQNKTRADDLTTQLSETASVVENLRTHCV
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SIEEVATVINNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRNLAGKTQQSTVHIKK
CHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
IISELQSYSLDATEKVDGCLNTITLTRETSIQSYDHLTNINAAIQSIYGSSTEMASAALQ
HHHHHHHCCCCCHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QSNAVEEITGTVIGIKEIINQNVTGIEESSKASNFLSELAEQQRSQLELFKIK
HCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNHSFIFKLSLNKPLLALLLAPVFTSLILFAIVAFLIDARNNEVEDNIIQTAERAALGSE
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IMQLRHNWQEIRVKNRDTMSENGQAMQEQQKELQKAFVSTNTHIKENILTSKVLSDAGKS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
DIANLQKTLIDYEKSINTSVKILTELYDAQIATPIFWQPMVEVLTFIGPIYNGSASDWEK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
ERITFTTNVERFYDSLSRMVNGRDLSEQKTAEQYLTSITSFLSQYNKYPEVKYFTDNVFG
CCEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHH
SYLSLYQESINTLKANSEQSKLRVKMVEDITNVISTVNARQVEFTQTLNQRSLNASKNVE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
NTQIWSWLGAALLSTFIALLLARNINNVLAAISKTIAAMAKQNLATLTNLSGTNELAVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
TNLDASIKNMANMVGSVREQSNDVASSSTELACVMTQSSSNAEEQSAQIEQIAAAVTELS
ECCCHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
ASSNLVADSAKNTELQATEAATLCELGQEIAEQNKTRADDLTTQLSETASVVENLRTHCV
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SIEEVATVINNISEQTNLLALNAAIEAARAGEMGRGFAVVADEVRNLAGKTQQSTVHIKK
CHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
IISELQSYSLDATEKVDGCLNTITLTRETSIQSYDHLTNINAAIQSIYGSSTEMASAALQ
HHHHHHHCCCCCHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QSNAVEEITGTVIGIKEIINQNVTGIEESSKASNFLSELAEQQRSQLELFKIK
HCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]