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The map label for this gene is mcp4 [H]

Identifier: 59712110

GI number: 59712110

Start: 1663205

End: 1664608

Strand: Direct

Name: mcp4 [H]

Synonym: VF_1503

Alternate gene names: 59712110

Gene position: 1663205-1664608 (Clockwise)

Preceding gene: 59712108

Following gene: 59712111

Centisome position: 57.4

GC content: 38.32

Gene sequence:

>1404_bases
ATGAAAGAAACGGCATTTCGTTGGATTGACAAATATCTTATTCACCTCAAGATCCAAGAAAAATTTTATTTACTCTTCTT
ACTTCCAGCTTTGGCACTTTTTAGCCTGATGTTTATTATGAACTCAGCCGCTGACAGTATGATGTCTAAAACTTTAGAAC
ATGAAGTTCAATTTATTGCTTCTATGTTAGATCAACAAAATGTATCTCGCCAAGATGCAATTACCCTACTTTCTCAATCA
GCAGAGTTTACTGTGGGTTCTGGTGAGCATACCGCTTATGTTGCTTCTGGAAACTACAGCATAAATGCAAATTCTGATGT
AACCCTATGGTCTACATTATCAAGCCTACAATTATCATTAATCATAGGCATTTTATTGGTAATGGCCATTGGTGTTTATT
ACATTATGACATTCATCGGTGGCGCTATGTTCACAATGAATAAAGCATTAGAAACACTTGAGTCTGGTGATCTTACGCAA
CGTCTAAACTTCTTCCCAGTAAGAGATGAATTTAGCACCATTGCTATGACCATTGATAAACTGGCAGAGCGTGAACAACA
GTTAGTGTTAGCCATGCAAGAATCCGTGGCACTAATTCAACAAATGAGTTCAGAATTAAGCCAAAACAGTTATAAAAGTT
CAGATGCTTCTGATAAGCAATTAGCTCAACTTGATCTCTTATCTAGCGCAGCAGAAGAGATGGCTACATCTATTCAAGAG
GTAGCAAGCTATACACATGAAGCCTCTTCTCAATCAACGGATGCGATGGAATCTGCACGCTTAGGGCAATCTCAAGTTGA
TTCTGCCGTTAGCTCTATTCAAGCTTTAGCACAAGAAATTAATCAAGCGGCAAATGCGGTTCAAGAATTAGATTCAGATG
CTGCAAAAATTGATGAAGTGGTGACTACAATCAACGCTATTTCTGAACAAACTAATTTATTAGCGCTTAATGCCGCAATT
GAAGCTGCACGAGCTGGTGAGCAAGGTCGTGGATTTGCAGTGGTTGCCGACGAAGTTCGTACATTAGCAAGCAGAACTCA
ACAAGCAACGGTTGAGATTCAGACCATGATTGAAGCATTACAAAATAACAGTAAGTCATTATTAACATTAACGTCGAACA
CGGTGACTAATGCTGAAACTGGTCAAGAATTAATGCATAAAGTTCACAATGATATTTCAAACATTGCAGAGCGTAACGAT
ACGATAGCTCAAAGTAATAATGAAATCGCAACCGCAGCAACTCAACAAGGAGAAGTTGCGGCAAGTATCGCTTCAACCGT
TGAAGATGTTCGTACTCAGTCAAATCAAGTTCATCAGATGATCAAAGATTCTGAATCGAATATCGAACAATTGCGAATAA
AAGGCCAAGATTTAGAGTTACTATTAAATGGCCTAAAAGCATAG

Upstream 100 bases:

>100_bases
GATTTTTGTGACATGCCTCACCTATAAGTGTCGATTATAATAAGAATTTCTTAATCATGAGATATTATCCTTCGCTCCTC
ATCATATATACGGATTTATT

Downstream 100 bases:

>100_bases
TTAATAAATTTAAGCCATTTATATTTTTTATTTATAGATGGCTTTCATCCCTTCCACTTAAATATATGTGTCAACATTCG
TTTGACGCTTATTTACAATA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKETAFRWIDKYLIHLKIQEKFYLLFLLPALALFSLMFIMNSAADSMMSKTLEHEVQFIASMLDQQNVSRQDAITLLSQS
AEFTVGSGEHTAYVASGNYSINANSDVTLWSTLSSLQLSLIIGILLVMAIGVYYIMTFIGGAMFTMNKALETLESGDLTQ
RLNFFPVRDEFSTIAMTIDKLAEREQQLVLAMQESVALIQQMSSELSQNSYKSSDASDKQLAQLDLLSSAAEEMATSIQE
VASYTHEASSQSTDAMESARLGQSQVDSAVSSIQALAQEINQAANAVQELDSDAAKIDEVVTTINAISEQTNLLALNAAI
EAARAGEQGRGFAVVADEVRTLASRTQQATVEIQTMIEALQNNSKSLLTLTSNTVTNAETGQELMHKVHNDISNIAERND
TIAQSNNEIATAATQQGEVAASIASTVEDVRTQSNQVHQMIKDSESNIEQLRIKGQDLELLLNGLKA

Sequences:

>Translated_467_residues
MKETAFRWIDKYLIHLKIQEKFYLLFLLPALALFSLMFIMNSAADSMMSKTLEHEVQFIASMLDQQNVSRQDAITLLSQS
AEFTVGSGEHTAYVASGNYSINANSDVTLWSTLSSLQLSLIIGILLVMAIGVYYIMTFIGGAMFTMNKALETLESGDLTQ
RLNFFPVRDEFSTIAMTIDKLAEREQQLVLAMQESVALIQQMSSELSQNSYKSSDASDKQLAQLDLLSSAAEEMATSIQE
VASYTHEASSQSTDAMESARLGQSQVDSAVSSIQALAQEINQAANAVQELDSDAAKIDEVVTTINAISEQTNLLALNAAI
EAARAGEQGRGFAVVADEVRTLASRTQQATVEIQTMIEALQNNSKSLLTLTSNTVTNAETGQELMHKVHNDISNIAERND
TIAQSNNEIATAATQQGEVAASIASTVEDVRTQSNQVHQMIKDSESNIEQLRIKGQDLELLLNGLKA
>Mature_467_residues
MKETAFRWIDKYLIHLKIQEKFYLLFLLPALALFSLMFIMNSAADSMMSKTLEHEVQFIASMLDQQNVSRQDAITLLSQS
AEFTVGSGEHTAYVASGNYSINANSDVTLWSTLSSLQLSLIIGILLVMAIGVYYIMTFIGGAMFTMNKALETLESGDLTQ
RLNFFPVRDEFSTIAMTIDKLAEREQQLVLAMQESVALIQQMSSELSQNSYKSSDASDKQLAQLDLLSSAAEEMATSIQE
VASYTHEASSQSTDAMESARLGQSQVDSAVSSIQALAQEINQAANAVQELDSDAAKIDEVVTTINAISEQTNLLALNAAI
EAARAGEQGRGFAVVADEVRTLASRTQQATVEIQTMIEALQNNSKSLLTLTSNTVTNAETGQELMHKVHNDISNIAERND
TIAQSNNEIATAATQQGEVAASIASTVEDVRTQSNQVHQMIKDSESNIEQLRIKGQDLELLLNGLKA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=230, Percent_Identity=34.3478260869565, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI2367378, Length=249, Percent_Identity=28.5140562248996, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788195, Length=249, Percent_Identity=30.5220883534137, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788194, Length=320, Percent_Identity=26.25, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789453, Length=293, Percent_Identity=29.3515358361775, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 50933; Mature: 50933

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETAFRWIDKYLIHLKIQEKFYLLFLLPALALFSLMFIMNSAADSMMSKTLEHEVQFIA
CCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLDQQNVSRQDAITLLSQSAEFTVGSGEHTAYVASGNYSINANSDVTLWSTLSSLQLSL
HHHHHCCCCHHHHHHHHHCCCCEEECCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHH
IIGILLVMAIGVYYIMTFIGGAMFTMNKALETLESGDLTQRLNFFPVRDEFSTIAMTIDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHH
LAEREQQLVLAMQESVALIQQMSSELSQNSYKSSDASDKQLAQLDLLSSAAEEMATSIQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VASYTHEASSQSTDAMESARLGQSQVDSAVSSIQALAQEINQAANAVQELDSDAAKIDEV
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VTTINAISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATVEIQTMIEAL
HHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
QNNSKSLLTLTSNTVTNAETGQELMHKVHNDISNIAERNDTIAQSNNEIATAATQQGEVA
HCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEHHCCCCHHH
ASIASTVEDVRTQSNQVHQMIKDSESNIEQLRIKGQDLELLLNGLKA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MKETAFRWIDKYLIHLKIQEKFYLLFLLPALALFSLMFIMNSAADSMMSKTLEHEVQFIA
CCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLDQQNVSRQDAITLLSQSAEFTVGSGEHTAYVASGNYSINANSDVTLWSTLSSLQLSL
HHHHHCCCCHHHHHHHHHCCCCEEECCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHH
IIGILLVMAIGVYYIMTFIGGAMFTMNKALETLESGDLTQRLNFFPVRDEFSTIAMTIDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHH
LAEREQQLVLAMQESVALIQQMSSELSQNSYKSSDASDKQLAQLDLLSSAAEEMATSIQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VASYTHEASSQSTDAMESARLGQSQVDSAVSSIQALAQEINQAANAVQELDSDAAKIDEV
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VTTINAISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATVEIQTMIEAL
HHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
QNNSKSLLTLTSNTVTNAETGQELMHKVHNDISNIAERNDTIAQSNNEIATAATQQGEVA
HCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEHHCCCCHHH
ASIASTVEDVRTQSNQVHQMIKDSESNIEQLRIKGQDLELLLNGLKA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]