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The map label for this gene is yeeZ [H]

Identifier: 59711995

GI number: 59711995

Start: 1535545

End: 1536327

Strand: Reverse

Name: yeeZ [H]

Synonym: VF_1388

Alternate gene names: 59711995

Gene position: 1536327-1535545 (Counterclockwise)

Preceding gene: 59711996

Following gene: 59711994

Centisome position: 53.02

GC content: 37.04

Gene sequence:

>783_bases
ATGACATCAATAAGCGTACTGGGATGTGGCTGGTTAGGGTTGCCTTTAGCAAAACACCTCGTTGATACTGGTTTTATGGT
CAAAGGCTCTATAAGAAGTTCGAATAAAATAAGTGAATTAGAAAAAAATCATATTAAACCGTATTTATTGGATATCGATG
CCGTTGAACAATCATGGAGTCAGTTTCTAACCTCCGATGTTTTAATCATTGCGATACCATCAAAAAATATCGAAGGGTTT
ACCTCTTTAATTCCTATTATTGAAGCCTCGTCGATAAAACATGTGCTATTTGTAAGCTCCACATCAGTTTATGAGGATGC
TAATCGAGTGGTTACTGAAGAAGATGCAACCATACCTTCTTCTGCATTATCACAGATTGAACGTTTATTTATGCAGTCGA
CTAAGTTCACAACAACCGTAATTCGATTTAGTGGACTTGTAGGGTATTCACGGAATCCAGGACGCTTTTTTGCCAAAAGT
GGGCGCTCTGTGAGTAACCCTGATGTACCAGTAAATATGATCCATCAGGATGACTGTATTGGGCTGATCACTCAAATTAT
TAAGCAAGAAAAATGGAATGAGATCTTTAATGCGTGTGCTGATACTCATCCAAGTAAGCGTGAGTTTTATACACAAGCAA
CGCAACGTATTGGCGTTGAAACGCCAACGTTTATCGAATCCAATGAACAAACATTTAAAATCATCAGTAATCATAAAATA
AAAGAAGCGTTAGGTTATGAATTTATTCACCCTGATGTGATGAATATTACGTATGATAGCTAA

Upstream 100 bases:

>100_bases
GGATTCTATTTATTGAAGGAAGAGCAGGACTATTTTGGTCTTGGCGAAGATCGTTTGGTACTTGCTTTAGATATAAATTA
AATAAAGATTAGGGACTATT

Downstream 100 bases:

>100_bases
CAGAGACCAAATAGGGAGTCATCATGAATCAATTATTAGCTGATAACCCATTAGTTACTACCGAGTGGCTAGCAGAACAT
ATTAATGATACTAATCTTGT

Product: epimerase

Products: dTDP-4-dehydro-6-deoxy-D-glucose; H2O

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTSISVLGCGWLGLPLAKHLVDTGFMVKGSIRSSNKISELEKNHIKPYLLDIDAVEQSWSQFLTSDVLIIAIPSKNIEGF
TSLIPIIEASSIKHVLFVSSTSVYEDANRVVTEEDATIPSSALSQIERLFMQSTKFTTTVIRFSGLVGYSRNPGRFFAKS
GRSVSNPDVPVNMIHQDDCIGLITQIIKQEKWNEIFNACADTHPSKREFYTQATQRIGVETPTFIESNEQTFKIISNHKI
KEALGYEFIHPDVMNITYDS

Sequences:

>Translated_260_residues
MTSISVLGCGWLGLPLAKHLVDTGFMVKGSIRSSNKISELEKNHIKPYLLDIDAVEQSWSQFLTSDVLIIAIPSKNIEGF
TSLIPIIEASSIKHVLFVSSTSVYEDANRVVTEEDATIPSSALSQIERLFMQSTKFTTTVIRFSGLVGYSRNPGRFFAKS
GRSVSNPDVPVNMIHQDDCIGLITQIIKQEKWNEIFNACADTHPSKREFYTQATQRIGVETPTFIESNEQTFKIISNHKI
KEALGYEFIHPDVMNITYDS
>Mature_259_residues
TSISVLGCGWLGLPLAKHLVDTGFMVKGSIRSSNKISELEKNHIKPYLLDIDAVEQSWSQFLTSDVLIIAIPSKNIEGFT
SLIPIIEASSIKHVLFVSSTSVYEDANRVVTEEDATIPSSALSQIERLFMQSTKFTTTVIRFSGLVGYSRNPGRFFAKSG
RSVSNPDVPVNMIHQDDCIGLITQIIKQEKWNEIFNACADTHPSKREFYTQATQRIGVETPTFIESNEQTFKIISNHKIK
EALGYEFIHPDVMNITYDS

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788327, Length=271, Percent_Identity=30.9963099630996, Blast_Score=138, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: 4.2.1.46

Molecular weight: Translated: 29096; Mature: 28965

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSISVLGCGWLGLPLAKHLVDTGFMVKGSIRSSNKISELEKNHIKPYLLDIDAVEQSWS
CCCEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHH
QFLTSDVLIIAIPSKNIEGFTSLIPIIEASSIKHVLFVSSTSVYEDANRVVTEEDATIPS
HHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHCCEECCCCCCCCH
SALSQIERLFMQSTKFTTTVIRFSGLVGYSRNPGRFFAKSGRSVSNPDVPVNMIHQDDCI
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCEEEECCCHHH
GLITQIIKQEKWNEIFNACADTHPSKREFYTQATQRIGVETPTFIESNEQTFKIISNHKI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEECCCCCEEEEHHCCHH
KEALGYEFIHPDVMNITYDS
HHHHCCHHCCCCEEEEEECC
>Mature Secondary Structure 
TSISVLGCGWLGLPLAKHLVDTGFMVKGSIRSSNKISELEKNHIKPYLLDIDAVEQSWS
CCEEEECCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHH
QFLTSDVLIIAIPSKNIEGFTSLIPIIEASSIKHVLFVSSTSVYEDANRVVTEEDATIPS
HHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHCCEECCCCCCCCH
SALSQIERLFMQSTKFTTTVIRFSGLVGYSRNPGRFFAKSGRSVSNPDVPVNMIHQDDCI
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCEEEECCCHHH
GLITQIIKQEKWNEIFNACADTHPSKREFYTQATQRIGVETPTFIESNEQTFKIISNHKI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEECCCCCEEEEHHCCHH
KEALGYEFIHPDVMNITYDS
HHHHCCHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDPglucose

Specific reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]