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The map label for this gene is recG [H]

Identifier: 59711961

GI number: 59711961

Start: 1497737

End: 1499125

Strand: Reverse

Name: recG [H]

Synonym: VF_1354

Alternate gene names: 59711961

Gene position: 1499125-1497737 (Counterclockwise)

Preceding gene: 59711962

Following gene: 59711960

Centisome position: 51.74

GC content: 36.43

Gene sequence:

>1389_bases
GTGAAAATCGTAGAATTACAAGAAAAAGAATCTTTGTATTATTGTACTAAAGATGAAGACCATTTTTTCGACAGAAAAGC
ATTTGGACTAAAAGGTGAAAAAGTCCAAAAAATTGCTGTTGCATTCGCTAATGCCGATGGTGGTGAAATACTTGTCGGAA
TTGCGGATGATAAAGACGAAGTTATTCCTGAAAAAAGATGGCAAGGTCAAGAATCAACAGAAGCTTATAACTCGGTTATT
CAGGCGTTGAGTGAACTTGTACCTTCTGTTGATTTCCGTTTTGATTTTTTAACAAGAGTTAATGAGTCTCGGAACTATGT
GTTAAGGGTTAAGATCAATAAAGGTTTATCTGTTCATGAAACAGCGAAGAAAAAAATTTTTCTTCGACAAGGGGCACAGT
CTCTTCCAGTAACCGCGCCAATTAAGATCTTAGAGTTAACACATGCGAAAGGAATAATTTCTGAAGAAGATTCTCTTGTT
AATTCTGCCTCAATAGACGAGCTTGATTCTAGTATTGAGCTTACAAAGTTCTTATCTGAGCTTCCAATTAGAGCACCTGA
TCCTATAACATTTCTTTTAAAAGAAAAGTTGGTCGACTCTGAGACATGGGCACCAACTGTTGCTGCAGTACTTTTGTTCG
CGGAAAATCCTTCAGCAGAACTACCTAAGCAATGTGCGATCCGGATTGTCCGCTATGATACAGATGGTGAAGATATTGAT
AGAGATGCTTTAACTGAAGACAATATCGCGATTGAAGGGTCTTTATATCAACAAATTCAGGACGCATATTCTAAGATTGA
GCTGTTTTTATCTAAAAATAAGGTATGGAAAGTAGAGGGATTAGTAGAAACTAAATACCCGAAAGAAACTATTTGGGAAA
TATTAGTAAATACTGTTATTCATCGTGATTACGCAATCTCAGATAATGTGTTGGTTAGCATTTTCAACAACCGAATCGAG
TTTAAAAGTCCAGGTCGATTTACTGGTTTCGTCACTGCTGAAAACATACTCGAAAATAGATGTTCACGAAATTCGAAAAT
TGTTCGTATTTTATCCAAGTATAAAGACTCCCCAAATAAAGATTTAGGTGAAGGCATGAATACAGCTTTTCAACGTATGC
GTTCTATGGGACTTCGAGATCCTGAAATTCTGGAGGATGGAAACTATGTGAAGATTATATTAAGGCATAGTTCCAATGAT
GATCCTGAGACCTTAATCATGAAATTCATCGAATCGAATGGTGAAATTAACAATCGTCAAGCTCGAGATCTCACAGGTAT
AGACCGAACAGAAAAGGTAACGTACCAATTTTCTAAATTAAGAGATAAAGGCTTGATTCAAAGAAAAGATTCCTCAACCG
GGCTGAAAAGTAGTTGGATTGCTGTGTAA

Upstream 100 bases:

>100_bases
AAGTAACATTAAAAGCAATAGCTGATGAAGTCAGGGCTAGTAAGAAAGCAAAAAGAAATGCTTAACAAAGTATTTAAGAG
TGAATTAATTAGGAACTACC

Downstream 100 bases:

>100_bases
ATTTAACAATTTGTTTAAGAGTGATTCGCAACGCGTGGAATTTTTACTATGCGTTGCGTTTAGTGCTTAAGGAGGCGTTG
TTTACAACTTAATGCGACGA

Product: DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MKIVELQEKESLYYCTKDEDHFFDRKAFGLKGEKVQKIAVAFANADGGEILVGIADDKDEVIPEKRWQGQESTEAYNSVI
QALSELVPSVDFRFDFLTRVNESRNYVLRVKINKGLSVHETAKKKIFLRQGAQSLPVTAPIKILELTHAKGIISEEDSLV
NSASIDELDSSIELTKFLSELPIRAPDPITFLLKEKLVDSETWAPTVAAVLLFAENPSAELPKQCAIRIVRYDTDGEDID
RDALTEDNIAIEGSLYQQIQDAYSKIELFLSKNKVWKVEGLVETKYPKETIWEILVNTVIHRDYAISDNVLVSIFNNRIE
FKSPGRFTGFVTAENILENRCSRNSKIVRILSKYKDSPNKDLGEGMNTAFQRMRSMGLRDPEILEDGNYVKIILRHSSND
DPETLIMKFIESNGEINNRQARDLTGIDRTEKVTYQFSKLRDKGLIQRKDSSTGLKSSWIAV

Sequences:

>Translated_462_residues
MKIVELQEKESLYYCTKDEDHFFDRKAFGLKGEKVQKIAVAFANADGGEILVGIADDKDEVIPEKRWQGQESTEAYNSVI
QALSELVPSVDFRFDFLTRVNESRNYVLRVKINKGLSVHETAKKKIFLRQGAQSLPVTAPIKILELTHAKGIISEEDSLV
NSASIDELDSSIELTKFLSELPIRAPDPITFLLKEKLVDSETWAPTVAAVLLFAENPSAELPKQCAIRIVRYDTDGEDID
RDALTEDNIAIEGSLYQQIQDAYSKIELFLSKNKVWKVEGLVETKYPKETIWEILVNTVIHRDYAISDNVLVSIFNNRIE
FKSPGRFTGFVTAENILENRCSRNSKIVRILSKYKDSPNKDLGEGMNTAFQRMRSMGLRDPEILEDGNYVKIILRHSSND
DPETLIMKFIESNGEINNRQARDLTGIDRTEKVTYQFSKLRDKGLIQRKDSSTGLKSSWIAV
>Mature_462_residues
MKIVELQEKESLYYCTKDEDHFFDRKAFGLKGEKVQKIAVAFANADGGEILVGIADDKDEVIPEKRWQGQESTEAYNSVI
QALSELVPSVDFRFDFLTRVNESRNYVLRVKINKGLSVHETAKKKIFLRQGAQSLPVTAPIKILELTHAKGIISEEDSLV
NSASIDELDSSIELTKFLSELPIRAPDPITFLLKEKLVDSETWAPTVAAVLLFAENPSAELPKQCAIRIVRYDTDGEDID
RDALTEDNIAIEGSLYQQIQDAYSKIELFLSKNKVWKVEGLVETKYPKETIWEILVNTVIHRDYAISDNVLVSIFNNRIE
FKSPGRFTGFVTAENILENRCSRNSKIVRILSKYKDSPNKDLGEGMNTAFQRMRSMGLRDPEILEDGNYVKIILRHSSND
DPETLIMKFIESNGEINNRQARDLTGIDRTEKVTYQFSKLRDKGLIQRKDSSTGLKSSWIAV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG2865

COG function: function code K; Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 52453; Mature: 52453

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVELQEKESLYYCTKDEDHFFDRKAFGLKGEKVQKIAVAFANADGGEILVGIADDKDE
CCCEEEECCCCEEEEECCCCCHHCCHHCCCCCHHHEEEEEEEECCCCCEEEEEEECCCHH
VIPEKRWQGQESTEAYNSVIQALSELVPSVDFRFDFLTRVNESRNYVLRVKINKGLSVHE
CCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHH
TAKKKIFLRQGAQSLPVTAPIKILELTHAKGIISEEDSLVNSASIDELDSSIELTKFLSE
HHHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
LPIRAPDPITFLLKEKLVDSETWAPTVAAVLLFAENPSAELPKQCAIRIVRYDTDGEDID
CCCCCCCCHHHHHHHHHCCCCCCHHHHEEEEEEECCCCCCCCHHHEEEEEEECCCCCCCC
RDALTEDNIAIEGSLYQQIQDAYSKIELFLSKNKVWKVEGLVETKYPKETIWEILVNTVI
HHHCCCCCEEECHHHHHHHHHHHHHHHHHEECCCEEEEECEEECCCCHHHHHHHHHHHHH
HRDYAISDNVLVSIFNNRIEFKSPGRFTGFVTAENILENRCSRNSKIVRILSKYKDSPNK
HCCEECCCCEEEEEECCEEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHCCCCCC
DLGEGMNTAFQRMRSMGLRDPEILEDGNYVKIILRHSSNDDPETLIMKFIESNGEINNRQ
HHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCC
ARDLTGIDRTEKVTYQFSKLRDKGLIQRKDSSTGLKSSWIAV
CCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKIVELQEKESLYYCTKDEDHFFDRKAFGLKGEKVQKIAVAFANADGGEILVGIADDKDE
CCCEEEECCCCEEEEECCCCCHHCCHHCCCCCHHHEEEEEEEECCCCCEEEEEEECCCHH
VIPEKRWQGQESTEAYNSVIQALSELVPSVDFRFDFLTRVNESRNYVLRVKINKGLSVHE
CCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHHH
TAKKKIFLRQGAQSLPVTAPIKILELTHAKGIISEEDSLVNSASIDELDSSIELTKFLSE
HHHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
LPIRAPDPITFLLKEKLVDSETWAPTVAAVLLFAENPSAELPKQCAIRIVRYDTDGEDID
CCCCCCCCHHHHHHHHHCCCCCCHHHHEEEEEEECCCCCCCCHHHEEEEEEECCCCCCCC
RDALTEDNIAIEGSLYQQIQDAYSKIELFLSKNKVWKVEGLVETKYPKETIWEILVNTVI
HHHCCCCCEEECHHHHHHHHHHHHHHHHHEECCCEEEEECEEECCCCHHHHHHHHHHHHH
HRDYAISDNVLVSIFNNRIEFKSPGRFTGFVTAENILENRCSRNSKIVRILSKYKDSPNK
HCCEECCCCEEEEEECCEEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHCCCCCC
DLGEGMNTAFQRMRSMGLRDPEILEDGNYVKIILRHSSNDDPETLIMKFIESNGEINNRQ
HHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCC
ARDLTGIDRTEKVTYQFSKLRDKGLIQRKDSSTGLKSSWIAV
CCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9603897 [H]