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The map label for this gene is yafC [H]

Identifier: 59711928

GI number: 59711928

Start: 1469501

End: 1470412

Strand: Direct

Name: yafC [H]

Synonym: VF_1321

Alternate gene names: 59711928

Gene position: 1469501-1470412 (Clockwise)

Preceding gene: 59711926

Following gene: 59711929

Centisome position: 50.72

GC content: 38.71

Gene sequence:

>912_bases
ATGTTAAAGCAAGCCAAACAAATGATTGTGTTCAACGCCTTAACTCAACAACAAAGCTTTACCAAAGCCGCACAGCTTCT
TGATATATCTCGAACTCAAGTAAGCCAACAAATTCAATTATTAGAAGAACGTTTAGGTGTCCAATTGGTTCAACGTACAA
CACGTTCATTTTCTCTAACTGAAGCAGGACAAACCTTCGCAGTTCATTGCGCTAATATCGCCGATGAAATTAACGAAGCT
GAAAATGAATTGCTGACCAATATTGATAACTTGCAAGGTAAATTACGTGTTGGTATCGCGCAATCATTTGCTACCAACCA
CATTCTTCCTTACCTATCAGAGCTGCACCATGCTTATCCACAACTAAATATAGAGATCACTTTGTTCGATCATAAGATCG
ATGTGATTGCAGAGCAATTAGACTTATGGATAGGTGTCATGGATTCCCCACCAGAAGGATTTGTTGCACGTCACCTAATT
GATTGCCACTTTGTATTAGTTGCAAGTCCGCTATACCTGGCAAAGCAAGGGATCCCTTACCATCCTTATGACTTAAAAAA
GCATAATTGCTTAACCTATATCAGTAGAGAGCGTAAAGATGACGTCTGGGGTTTTCATAAAGAGGATGAAAACCTCCAGA
TAAAAGTGTCTGGTAACTACCGTATTGACTCAGCTGATGCCATTCGTAATGCCACCATAGCAGGTAATGGTATTGGTTAT
ATTGCCACTTATCTTCTTTCTGATGAATTGCAAGCAGGTAAACTTGTTCAACTCTTGCCTGATTGGGAATTAAACCAATC
AATGCCCCTATATGCCGTTTATCCAAGACGAAAATTCTTGCCTAAGAAGGTACATGTTTTCATGGAATTTGTTCGTCAGC
ATATTAATGAAACACAAATTGGTAAAATTTAA

Upstream 100 bases:

>100_bases
GTTTCTATGGATACCAAAAACAAACACCTAAGCTACTTTATTCAGCACAGCCCCTCCATTACAATGGAGTCAACCATACT
AATAATGAATAGAGATATAC

Downstream 100 bases:

>100_bases
TCATTTTACTGATGGGATTATTAATCAAAAATCCACCACAATTGTTTCATATAATAAAAACTAACTTCTAAATATGTGAT
AAAAGCCTCAATTAAGAGGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MLKQAKQMIVFNALTQQQSFTKAAQLLDISRTQVSQQIQLLEERLGVQLVQRTTRSFSLTEAGQTFAVHCANIADEINEA
ENELLTNIDNLQGKLRVGIAQSFATNHILPYLSELHHAYPQLNIEITLFDHKIDVIAEQLDLWIGVMDSPPEGFVARHLI
DCHFVLVASPLYLAKQGIPYHPYDLKKHNCLTYISRERKDDVWGFHKEDENLQIKVSGNYRIDSADAIRNATIAGNGIGY
IATYLLSDELQAGKLVQLLPDWELNQSMPLYAVYPRRKFLPKKVHVFMEFVRQHINETQIGKI

Sequences:

>Translated_303_residues
MLKQAKQMIVFNALTQQQSFTKAAQLLDISRTQVSQQIQLLEERLGVQLVQRTTRSFSLTEAGQTFAVHCANIADEINEA
ENELLTNIDNLQGKLRVGIAQSFATNHILPYLSELHHAYPQLNIEITLFDHKIDVIAEQLDLWIGVMDSPPEGFVARHLI
DCHFVLVASPLYLAKQGIPYHPYDLKKHNCLTYISRERKDDVWGFHKEDENLQIKVSGNYRIDSADAIRNATIAGNGIGY
IATYLLSDELQAGKLVQLLPDWELNQSMPLYAVYPRRKFLPKKVHVFMEFVRQHINETQIGKI
>Mature_303_residues
MLKQAKQMIVFNALTQQQSFTKAAQLLDISRTQVSQQIQLLEERLGVQLVQRTTRSFSLTEAGQTFAVHCANIADEINEA
ENELLTNIDNLQGKLRVGIAQSFATNHILPYLSELHHAYPQLNIEITLFDHKIDVIAEQLDLWIGVMDSPPEGFVARHLI
DCHFVLVASPLYLAKQGIPYHPYDLKKHNCLTYISRERKDDVWGFHKEDENLQIKVSGNYRIDSADAIRNATIAGNGIGY
IATYLLSDELQAGKLVQLLPDWELNQSMPLYAVYPRRKFLPKKVHVFMEFVRQHINETQIGKI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=303, Percent_Identity=26.7326732673267, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=30.8219178082192, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=30.6620209059233, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787128, Length=302, Percent_Identity=29.4701986754967, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=31.25, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1789639, Length=302, Percent_Identity=28.8079470198675, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=23.972602739726, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789173, Length=248, Percent_Identity=31.0483870967742, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=26.7796610169492, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788706, Length=301, Percent_Identity=24.5847176079734, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=29.0780141843972, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788748, Length=172, Percent_Identity=31.9767441860465, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787601, Length=170, Percent_Identity=26.4705882352941, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790011, Length=306, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=295, Percent_Identity=21.0169491525424, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786448, Length=299, Percent_Identity=24.0802675585284, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34606; Mature: 34606

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQAKQMIVFNALTQQQSFTKAAQLLDISRTQVSQQIQLLEERLGVQLVQRTTRSFSLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEC
EAGQTFAVHCANIADEINEAENELLTNIDNLQGKLRVGIAQSFATNHILPYLSELHHAYP
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
QLNIEITLFDHKIDVIAEQLDLWIGVMDSPPEGFVARHLIDCHFVLVASPLYLAKQGIPY
CEEEEEEEECCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCC
HPYDLKKHNCLTYISRERKDDVWGFHKEDENLQIKVSGNYRIDSADAIRNATIAGNGIGY
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCEEECCHHHHHCCEECCCCHHH
IATYLLSDELQAGKLVQLLPDWELNQSMPLYAVYPRRKFLPKKVHVFMEFVRQHINETQI
HHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEECCCHHCCHHHHHHHHHHHHHHCCCCCC
GKI
CCC
>Mature Secondary Structure
MLKQAKQMIVFNALTQQQSFTKAAQLLDISRTQVSQQIQLLEERLGVQLVQRTTRSFSLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEC
EAGQTFAVHCANIADEINEAENELLTNIDNLQGKLRVGIAQSFATNHILPYLSELHHAYP
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
QLNIEITLFDHKIDVIAEQLDLWIGVMDSPPEGFVARHLIDCHFVLVASPLYLAKQGIPY
CEEEEEEEECCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHCCCCC
HPYDLKKHNCLTYISRERKDDVWGFHKEDENLQIKVSGNYRIDSADAIRNATIAGNGIGY
CCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCEEECCHHHHHCCEECCCCHHH
IATYLLSDELQAGKLVQLLPDWELNQSMPLYAVYPRRKFLPKKVHVFMEFVRQHINETQI
HHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEECCCHHCCHHHHHHHHHHHHHHCCCCCC
GKI
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]