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The map label for this gene is grxC [C]

Identifier: 59711869

GI number: 59711869

Start: 1403532

End: 1404107

Strand: Direct

Name: grxC [C]

Synonym: VF_1262

Alternate gene names: 59711869

Gene position: 1403532-1404107 (Clockwise)

Preceding gene: 59711868

Following gene: 59711870

Centisome position: 48.44

GC content: 40.97

Gene sequence:

>576_bases
ATGAAACCAGTAAAAATTACATTATATCGTTGGGCAGGCAGTTGGGGTCCATTTAAAGTCAATATTCCGTGTGGAGAGTG
CACCTTAACGAAAGACATTCTGGAAGATACATTTAACACTGAGCTTGATGGTATTCCTATTGAGCTTGAAGTGAAAGATT
GGCTGTCTTACTGGTGGGAGCCTTTAAAGCTCAAAGCGTGGCATGCTCCGATTATCATTGTTGAAGATAAAGTGATAAGC
CAAGGTGAGGCGTTAAATCGTGGTGTTTTGGTTCAAGCTGTTATAGCTCAAGTTGCCAAGCGTGATGATATCAAAGGTAA
CGTGGTATTTGGTAAAGCAACATGTCCTTATTGTATTAAAGCGAAAGCTGCATTGGATGAGGCCGGAGTTGAATACACTT
ATCACGATGTAGTGAAAGACAGTGCAGCCTTGTATCGAATGATCCCAGAGGTTAAAGCCATTATTGGTGAGAAAACACCT
GTGACAGTGCCTCAAATTTGGTTGGATGGTAAATACGTTGGTGGCTTTGATGATTTATCAAAACAGATGAACACTGATGT
GAAAGCGGGGAATTAA

Upstream 100 bases:

>100_bases
TCAATCATAAAGGTTGACTTAAATTGAAATTCAACTAAATTAAACTAAACGGTTCAGTTTAATTTTAAGATAAATCAGTT
TGCTGATAGGGGAAGTCGCA

Downstream 100 bases:

>100_bases
TATGAATAAAAAACTGATTTTATTACTTATTCTTTTTGCGTCATTTGCTGCAGTGTATGTCAATTTCGGGCATTTATTGA
CACTTGAGCAGGTGAAAGCA

Product: glutaredoxin

Products: NA

Alternate protein names: Glutaredoxin Family Protein; Glutaredoxin-Related Protein

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MKPVKITLYRWAGSWGPFKVNIPCGECTLTKDILEDTFNTELDGIPIELEVKDWLSYWWEPLKLKAWHAPIIIVEDKVIS
QGEALNRGVLVQAVIAQVAKRDDIKGNVVFGKATCPYCIKAKAALDEAGVEYTYHDVVKDSAALYRMIPEVKAIIGEKTP
VTVPQIWLDGKYVGGFDDLSKQMNTDVKAGN

Sequences:

>Translated_191_residues
MKPVKITLYRWAGSWGPFKVNIPCGECTLTKDILEDTFNTELDGIPIELEVKDWLSYWWEPLKLKAWHAPIIIVEDKVIS
QGEALNRGVLVQAVIAQVAKRDDIKGNVVFGKATCPYCIKAKAALDEAGVEYTYHDVVKDSAALYRMIPEVKAIIGEKTP
VTVPQIWLDGKYVGGFDDLSKQMNTDVKAGN
>Mature_191_residues
MKPVKITLYRWAGSWGPFKVNIPCGECTLTKDILEDTFNTELDGIPIELEVKDWLSYWWEPLKLKAWHAPIIIVEDKVIS
QGEALNRGVLVQAVIAQVAKRDDIKGNVVFGKATCPYCIKAKAALDEAGVEYTYHDVVKDSAALYRMIPEVKAIIGEKTP
VTVPQIWLDGKYVGGFDDLSKQMNTDVKAGN

Specific function: The Disulfide Bond Functions As An Electron Carrier In The Glutathione-Dependent Synthesis Of Deoxyribonucleotides By The Enzyme Ribonucleotide Reductase. In Addition, It Is Also Involved In Reducing Some Disulfides In A Coupled System With Glutathione R

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21311; Mature: 21311

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVKITLYRWAGSWGPFKVNIPCGECTLTKDILEDTFNTELDGIPIELEVKDWLSYWWE
CCCEEEEEEEECCCCCCEEEECCCCCCEECHHHHHHHCCCCCCCCEEEEEHHHHHHHCCC
PLKLKAWHAPIIIVEDKVISQGEALNRGVLVQAVIAQVAKRDDIKGNVVFGKATCPYCIK
CEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHEE
AKAALDEAGVEYTYHDVVKDSAALYRMIPEVKAIIGEKTPVTVPQIWLDGKYVGGFDDLS
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEECCHHHHH
KQMNTDVKAGN
HHHCCCCCCCC
>Mature Secondary Structure
MKPVKITLYRWAGSWGPFKVNIPCGECTLTKDILEDTFNTELDGIPIELEVKDWLSYWWE
CCCEEEEEEEECCCCCCEEEECCCCCCEECHHHHHHHCCCCCCCCEEEEEHHHHHHHCCC
PLKLKAWHAPIIIVEDKVISQGEALNRGVLVQAVIAQVAKRDDIKGNVVFGKATCPYCIK
CEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHEE
AKAALDEAGVEYTYHDVVKDSAALYRMIPEVKAIIGEKTPVTVPQIWLDGKYVGGFDDLS
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEECCHHHHH
KQMNTDVKAGN
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA