Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 59711823

GI number: 59711823

Start: 1351728

End: 1352198

Strand: Direct

Name: infC [H]

Synonym: VF_1216

Alternate gene names: 59711823

Gene position: 1351728-1352198 (Clockwise)

Preceding gene: 172087694

Following gene: 59711824

Centisome position: 46.65

GC content: 45.22

Gene sequence:

>471_bases
GTGCGCCTAACAGGCCTAGATGGTGAATCAGTAGGCATCGTTTCTTTAAACGAAGCTCTGGATGCAGCACTTGAAGCTGG
TGTTGACTTAGTTGAAATCAGCCCAAATGCCGAGCCACCAGTTGGTCGTGTGATGGACTATGGCAAATTCCTCTTCGAAA
AGGCGAAGGCTGCTAAAGAACAGAAGAAAAAGCAAAAACAGGTTCAGATCAAGGAAATTAAATTCCGACCTGGAACTGAT
GTAGGAGACTATCAGGTAAAACTACGCAACCTGACTGGTTTCCTAGAAGACGGCAACAAAGTGAAGGTAACAATTCGCTT
CCGTGGCCGCGAAATGGCTCACCAAAACATCGGTGTTGACGTTCTTAATCGTTTGAAAGCGGATACTGAAGAATTTGCAG
TAGTCGAATCTTTCCCAACGAGAATTGAAGGTCGCCAGATGATTATGGTGTTGGCCCCTAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
TACTGTGGAGGAATAAGGTATTAAAGGCGGAAAAAGAGCCCAACAGCCGGCTAAACAAAATGCTCATCGTCTAAACGGTG
AAATTCGTGGCGTTAAAGAA

Downstream 100 bases:

>100_bases
TTTAGTGCATTCAAGTAATACAGCAGGGTAGCTGTTCGCAGTTACCCTGTTTTATTCGCCTAATTACTGTATGTTTAATC
ACGCAACAATGCGGAGTTAT

Product: protein chain initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MRLTGLDGESVGIVSLNEALDAALEAGVDLVEISPNAEPPVGRVMDYGKFLFEKAKAAKEQKKKQKQVQIKEIKFRPGTD
VGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQNIGVDVLNRLKADTEEFAVVESFPTRIEGRQMIMVLAPKKK

Sequences:

>Translated_156_residues
MRLTGLDGESVGIVSLNEALDAALEAGVDLVEISPNAEPPVGRVMDYGKFLFEKAKAAKEQKKKQKQVQIKEIKFRPGTD
VGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQNIGVDVLNRLKADTEEFAVVESFPTRIEGRQMIMVLAPKKK
>Mature_156_residues
MRLTGLDGESVGIVSLNEALDAALEAGVDLVEISPNAEPPVGRVMDYGKFLFEKAKAAKEQKKKQKQVQIKEIKFRPGTD
VGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQNIGVDVLNRLKADTEEFAVVESFPTRIEGRQMIMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=156, Percent_Identity=77.5641025641026, Blast_Score=228, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17428; Mature: 17428

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTGLDGESVGIVSLNEALDAALEAGVDLVEISPNAEPPVGRVMDYGKFLFEKAKAAKE
CCCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
QKKKQKQVQIKEIKFRPGTDVGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQNIGVD
HHHHHHCCEEEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEEEECCCHHHHHCCCHH
VLNRLKADTEEFAVVESFPTRIEGRQMIMVLAPKKK
HHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MRLTGLDGESVGIVSLNEALDAALEAGVDLVEISPNAEPPVGRVMDYGKFLFEKAKAAKE
CCCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
QKKKQKQVQIKEIKFRPGTDVGDYQVKLRNLTGFLEDGNKVKVTIRFRGREMAHQNIGVD
HHHHHHCCEEEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEEEECCCHHHHHCCCHH
VLNRLKADTEEFAVVESFPTRIEGRQMIMVLAPKKK
HHHHHCCCHHHHHHHHHCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA