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The map label for this gene is macB [H]

Identifier: 59711770

GI number: 59711770

Start: 1290061

End: 1291278

Strand: Direct

Name: macB [H]

Synonym: VF_1163

Alternate gene names: 59711770

Gene position: 1290061-1291278 (Clockwise)

Preceding gene: 59711769

Following gene: 59711771

Centisome position: 44.52

GC content: 37.52

Gene sequence:

>1218_bases
ATGATGGCGTTATTCTCTCAAACAATTCAAACTTTATTGGCTCATCGTTTGAGAGGTTTTTTGGCTATCCTAGCTATTGT
ATGGGGAATTATTTCAGTTTTGGTTTTAGTTGCACTTGGTGAAGGCTTCTATCAAATAAATATGAAATCGTTTTCCTTAT
TAATGAATGATACTCAGGTAGTCTTTTTGGGGCAATCTACTACCAAAGAGTGGAAAGGAAGAGCAGCAAAAAGGCTAATA
GTACCTTCTGAAGCAGAAGTTCGTCAAATACGTAATCATCCTGCTATTGAGAATATATCAGTGATATACAGTAAACGGAA
TGCTAGCGTCACGGATAGTCAAGGTCGTTCTTTGCCGAGGAATGTTACAGGTATAGATGATCAATTTATTGAATTGCGAA
ATGTGAAATTAAGCAAGGGTTCACGACAAGTTAACCATGGTGATTTGGTTAATCATAAGCGTGTTGCCTTGGTTAGTTGG
CAATTAGCAGATATAGGCTCTTTACATATAGGAAGCTCTTTAAATATTAATGGTATTCCTTTTAAGGTTATTGGTATTAC
AAAGAAAAATGAAGATGGGATTTCACTTGGTGATGTTAGCCAAGCAATGATCCCAAGCACAGTATTTACTGATTTGTGGG
AGAGTGAACCAGATATGCTATTTATTTCCCCTGTAGAAGGTGTTTCTAGTTGGCTATTGAGAAAGAATATATTGTCATTT
TTTGCGAATCAACAATACTTTGATCCTAATGATAAAGATGCGATGTATATGCCTGACTTTGGACAGGAAGCGGCATTTTT
TAAAAAATTATTAAGGGGCATTCAACTGTTCTTAGGAGCAAATGGTGCTATGACTCTAGTTGTTGGCTCACTAGGTGTCG
CAAATATAATGTTTTTATCAGTGACTGAACGAACGAGAGAAGTTGGGGTTCGACTTGCGATAGGTGCGACACCAAATAAT
ATCTTAGGCCAATTTTTAATAGAAGGAGGCATTCTCATTGCATGTGGAACCGCTATTGGAATTGTATTCTCCTATGGCAT
AGTTATGTTATTAAATATGATTGGTATGCCTGAATGGTTAGGTGAACCAATGATCACGCTTGATGCTATTAAAATATCAT
TAGGGGTGACAGCTGTATTGGCATTATTAGCAGCGTATTTTCCTGCGCGTCGTGCATCGAATTTACTTCCAGTCATTGCC
TTAAGTGCGAGGGCTTGA

Upstream 100 bases:

>100_bases
CATTGCTTTATCAATATTGGAGGGATCGTATTTCCTTACTTAAGTCTGTCGGTAGATTAGATGATGAAACTATAACCTTG
ATTTCACAGGCACTGCAATC

Downstream 100 bases:

>100_bases
TTAATGCTATTGCCAATGAGACTAATATTTCAAGAAATGGCTGCTGAGAAAGTACGCTTGAGTTTACTTCTCTTAGCTGT
GGCATGGGCGACATTATGTA

Product: export ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MMALFSQTIQTLLAHRLRGFLAILAIVWGIISVLVLVALGEGFYQINMKSFSLLMNDTQVVFLGQSTTKEWKGRAAKRLI
VPSEAEVRQIRNHPAIENISVIYSKRNASVTDSQGRSLPRNVTGIDDQFIELRNVKLSKGSRQVNHGDLVNHKRVALVSW
QLADIGSLHIGSSLNINGIPFKVIGITKKNEDGISLGDVSQAMIPSTVFTDLWESEPDMLFISPVEGVSSWLLRKNILSF
FANQQYFDPNDKDAMYMPDFGQEAAFFKKLLRGIQLFLGANGAMTLVVGSLGVANIMFLSVTERTREVGVRLAIGATPNN
ILGQFLIEGGILIACGTAIGIVFSYGIVMLLNMIGMPEWLGEPMITLDAIKISLGVTAVLALLAAYFPARRASNLLPVIA
LSARA

Sequences:

>Translated_405_residues
MMALFSQTIQTLLAHRLRGFLAILAIVWGIISVLVLVALGEGFYQINMKSFSLLMNDTQVVFLGQSTTKEWKGRAAKRLI
VPSEAEVRQIRNHPAIENISVIYSKRNASVTDSQGRSLPRNVTGIDDQFIELRNVKLSKGSRQVNHGDLVNHKRVALVSW
QLADIGSLHIGSSLNINGIPFKVIGITKKNEDGISLGDVSQAMIPSTVFTDLWESEPDMLFISPVEGVSSWLLRKNILSF
FANQQYFDPNDKDAMYMPDFGQEAAFFKKLLRGIQLFLGANGAMTLVVGSLGVANIMFLSVTERTREVGVRLAIGATPNN
ILGQFLIEGGILIACGTAIGIVFSYGIVMLLNMIGMPEWLGEPMITLDAIKISLGVTAVLALLAAYFPARRASNLLPVIA
LSARA
>Mature_405_residues
MMALFSQTIQTLLAHRLRGFLAILAIVWGIISVLVLVALGEGFYQINMKSFSLLMNDTQVVFLGQSTTKEWKGRAAKRLI
VPSEAEVRQIRNHPAIENISVIYSKRNASVTDSQGRSLPRNVTGIDDQFIELRNVKLSKGSRQVNHGDLVNHKRVALVSW
QLADIGSLHIGSSLNINGIPFKVIGITKKNEDGISLGDVSQAMIPSTVFTDLWESEPDMLFISPVEGVSSWLLRKNILSF
FANQQYFDPNDKDAMYMPDFGQEAAFFKKLLRGIQLFLGANGAMTLVVGSLGVANIMFLSVTERTREVGVRLAIGATPNN
ILGQFLIEGGILIACGTAIGIVFSYGIVMLLNMIGMPEWLGEPMITLDAIKISLGVTAVLALLAAYFPARRASNLLPVIA
LSARA

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=235, Percent_Identity=28.936170212766, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44249; Mature: 44249

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMALFSQTIQTLLAHRLRGFLAILAIVWGIISVLVLVALGEGFYQINMKSFSLLMNDTQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHEEEEECCCEE
VFLGQSTTKEWKGRAAKRLIVPSEAEVRQIRNHPAIENISVIYSKRNASVTDSQGRSLPR
EEEECCCCHHHHCHHHCEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCC
NVTGIDDQFIELRNVKLSKGSRQVNHGDLVNHKRVALVSWQLADIGSLHIGSSLNINGIP
CCCCCCHHHHHHHCCEECCCCCCCCCCCCCCCCEEEEEEEEHHCCCCEEECCCCCCCCCC
FKVIGITKKNEDGISLGDVSQAMIPSTVFTDLWESEPDMLFISPVEGVSSWLLRKNILSF
EEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHH
FANQQYFDPNDKDAMYMPDFGQEAAFFKKLLRGIQLFLGANGAMTLVVGSLGVANIMFLS
HCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHEEEEE
VTERTREVGVRLAIGATPNNILGQFLIEGGILIACGTAIGIVFSYGIVMLLNMIGMPEWL
EHHHHHHCCEEEEECCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHH
GEPMITLDAIKISLGVTAVLALLAAYFPARRASNLLPVIALSARA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
>Mature Secondary Structure
MMALFSQTIQTLLAHRLRGFLAILAIVWGIISVLVLVALGEGFYQINMKSFSLLMNDTQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHEEEEECCCEE
VFLGQSTTKEWKGRAAKRLIVPSEAEVRQIRNHPAIENISVIYSKRNASVTDSQGRSLPR
EEEECCCCHHHHCHHHCEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCC
NVTGIDDQFIELRNVKLSKGSRQVNHGDLVNHKRVALVSWQLADIGSLHIGSSLNINGIP
CCCCCCHHHHHHHCCEECCCCCCCCCCCCCCCCEEEEEEEEHHCCCCEEECCCCCCCCCC
FKVIGITKKNEDGISLGDVSQAMIPSTVFTDLWESEPDMLFISPVEGVSSWLLRKNILSF
EEEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHH
FANQQYFDPNDKDAMYMPDFGQEAAFFKKLLRGIQLFLGANGAMTLVVGSLGVANIMFLS
HCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHEEEEE
VTERTREVGVRLAIGATPNNILGQFLIEGGILIACGTAIGIVFSYGIVMLLNMIGMPEWL
EHHHHHHCCEEEEECCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCHHHH
GEPMITLDAIKISLGVTAVLALLAAYFPARRASNLLPVIALSARA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]