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The map label for this gene is nahR [H]

Identifier: 59711679

GI number: 59711679

Start: 1185368

End: 1186306

Strand: Direct

Name: nahR [H]

Synonym: VF_1072

Alternate gene names: 59711679

Gene position: 1185368-1186306 (Clockwise)

Preceding gene: 59711675

Following gene: 59711687

Centisome position: 40.91

GC content: 36.53

Gene sequence:

>939_bases
ATGAAGCATAAAATTCATCAGCTGGATCTTAATTTACTCAAAGTGTTTACGGTTTTATTAGAAGTTCGTAATACCCGAAA
GGCATCTGAACGTTTGTTTTTAAGCCAACCTGGTGTCAGTAGGGCACTTGCTCGATTAAGAGACTTCTTTGAAGATGAAT
TGTTTATACGCAGTCATTATGGCTTAACGCCAACCCCTAAGGCATTAGAGATTGGAGATAATATTGCGCCTGCAATGACT
TTACTTTTTTCTGCTTTAGAACCATCAGATAAATTTGATAGTTCACAGTTAGAGGGAAGAATAAATATCGCTATGAATGG
TTTTATTGCTCCGTCCATTGCTTCTAATTTGTGTGGCATTATTCTAGAAAAAGCACCAAATGTTGAAGTGGTATTTTCTA
ATTGGGACAGAGCAACGCCTGAAAATATTTTGCATGATCAAATACAGTTAGGTTTAAATTATTTTCCATTAGAAATTTCA
AAACAGCTTTCTCAGTCGGTACTGACCACCGATCGTTTTGTATTGATTGGACGTAAAGAACACCCTCTAATTACGGGTGA
AGAAAGCTTTGAAAATGCAGCTCAATTAGATATTGCGACACTTGTTATCCCAAATTGGAATGAGCATAAAGCTTATGTGG
TTAATTCTTTAAAATCATTAAATAAAGAATGTCGCATGAGGCTGAGAAGCAGCTACCTTGATGTCATCTTAAATTCAATA
CAACGAACGGATATGCTTTTTCCATGCTCAGAATCATTAGCAAATACCTTAGGTAGTGACTTTCAGAAACTACTATTGCC
AGATGATGTTATTCAACCGGGTGGAGAAATAGGGCTTGTTGTAGCGAGTAAAAATCGGAGAACTCCTTTAATTAAATGGT
TAAAGGAGTGTACTCAAGAGGCGGCCGCTGAGATTAAAACTTATAATTTAAGCCAGTAG

Upstream 100 bases:

>100_bases
ACCTAGATAATGAATTGAAGGGATATGAGATATATCATTTAGTCATTATTGGTGGCGTGATTCGTTTATGGTACTAATTT
GGATAAGTAAGTAGGACAAA

Downstream 100 bases:

>100_bases
AAATAATGTATTCAGAGTTATCGTAGAAAGTGATATTTGATTGTTCTGTGCCATATCCTGCAAAAGCAACGAGCGACCAA
TCTTTCCAATCCATGATATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKHKIHQLDLNLLKVFTVLLEVRNTRKASERLFLSQPGVSRALARLRDFFEDELFIRSHYGLTPTPKALEIGDNIAPAMT
LLFSALEPSDKFDSSQLEGRINIAMNGFIAPSIASNLCGIILEKAPNVEVVFSNWDRATPENILHDQIQLGLNYFPLEIS
KQLSQSVLTTDRFVLIGRKEHPLITGEESFENAAQLDIATLVIPNWNEHKAYVVNSLKSLNKECRMRLRSSYLDVILNSI
QRTDMLFPCSESLANTLGSDFQKLLLPDDVIQPGGEIGLVVASKNRRTPLIKWLKECTQEAAAEIKTYNLSQ

Sequences:

>Translated_312_residues
MKHKIHQLDLNLLKVFTVLLEVRNTRKASERLFLSQPGVSRALARLRDFFEDELFIRSHYGLTPTPKALEIGDNIAPAMT
LLFSALEPSDKFDSSQLEGRINIAMNGFIAPSIASNLCGIILEKAPNVEVVFSNWDRATPENILHDQIQLGLNYFPLEIS
KQLSQSVLTTDRFVLIGRKEHPLITGEESFENAAQLDIATLVIPNWNEHKAYVVNSLKSLNKECRMRLRSSYLDVILNSI
QRTDMLFPCSESLANTLGSDFQKLLLPDDVIQPGGEIGLVVASKNRRTPLIKWLKECTQEAAAEIKTYNLSQ
>Mature_312_residues
MKHKIHQLDLNLLKVFTVLLEVRNTRKASERLFLSQPGVSRALARLRDFFEDELFIRSHYGLTPTPKALEIGDNIAPAMT
LLFSALEPSDKFDSSQLEGRINIAMNGFIAPSIASNLCGIILEKAPNVEVVFSNWDRATPENILHDQIQLGLNYFPLEIS
KQLSQSVLTTDRFVLIGRKEHPLITGEESFENAAQLDIATLVIPNWNEHKAYVVNSLKSLNKECRMRLRSSYLDVILNSI
QRTDMLFPCSESLANTLGSDFQKLLLPDDVIQPGGEIGLVVASKNRRTPLIKWLKECTQEAAAEIKTYNLSQ

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=186, Percent_Identity=29.5698924731183, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786820, Length=257, Percent_Identity=27.2373540856031, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081766, Length=200, Percent_Identity=29, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35132; Mature: 35132

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHKIHQLDLNLLKVFTVLLEVRNTRKASERLFLSQPGVSRALARLRDFFEDELFIRSHY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEECC
GLTPTPKALEIGDNIAPAMTLLFSALEPSDKFDSSQLEGRINIAMNGFIAPSIASNLCGI
CCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCHHCCCEEEEEECCEECHHHHHHHHHH
ILEKAPNVEVVFSNWDRATPENILHDQIQLGLNYFPLEISKQLSQSVLTTDRFVLIGRKE
HHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
HPLITGEESFENAAQLDIATLVIPNWNEHKAYVVNSLKSLNKECRMRLRSSYLDVILNSI
CCEECCCHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRTDMLFPCSESLANTLGSDFQKLLLPDDVIQPGGEIGLVVASKNRRTPLIKWLKECTQE
HHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
AAAEIKTYNLSQ
HHHHHHHCCCCC
>Mature Secondary Structure
MKHKIHQLDLNLLKVFTVLLEVRNTRKASERLFLSQPGVSRALARLRDFFEDELFIRSHY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEECC
GLTPTPKALEIGDNIAPAMTLLFSALEPSDKFDSSQLEGRINIAMNGFIAPSIASNLCGI
CCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCHHCCCEEEEEECCEECHHHHHHHHHH
ILEKAPNVEVVFSNWDRATPENILHDQIQLGLNYFPLEISKQLSQSVLTTDRFVLIGRKE
HHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
HPLITGEESFENAAQLDIATLVIPNWNEHKAYVVNSLKSLNKECRMRLRSSYLDVILNSI
CCEECCCHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRTDMLFPCSESLANTLGSDFQKLLLPDDVIQPGGEIGLVVASKNRRTPLIKWLKECTQE
HHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
AAAEIKTYNLSQ
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]