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The map label for this gene is dcuC [H]

Identifier: 59711668

GI number: 59711668

Start: 1172014

End: 1173381

Strand: Direct

Name: dcuC [H]

Synonym: VF_1061

Alternate gene names: 59711668

Gene position: 1172014-1173381 (Clockwise)

Preceding gene: 59711667

Following gene: 59711670

Centisome position: 40.45

GC content: 40.64

Gene sequence:

>1368_bases
ATGGCTTCGTTATTACTTGTTCTTATCGTTGTTGTTATTGCGGCAAGGATGATTTTAAAGGGGTATAAAGCTGAACCTAC
TTTATTAATGTCAGGGACGATATTGATTTTCGCAACTGGACTTTTTGGCTGGGGCCCAATGTTGCCAGCTTCGGTTACAT
CGACTAATTTTTCAGGATTTGAGCCCTTTAAATACATACAATTTTTAATGGGGTATCGAGCGGGAGCGCTGGGGTTAATG
ATTATGGCTTTGGTCGGTTTTGCTGATTATATGAGTCATATTGGAGCTAACGATGTTGTCGTTCGTTTAGCCACTAAGCC
ACTAAGTCGTATTCAAAATAAAAACATTATGTTGTTCTTTGCTTACTGTATGGCAAGTATCTTACAACTGGCAATTCCTT
CAGCTACCGGTCTTGGCGTGTTATTGATGGGAACACTTTATCCTGTGATGTTGGGATTGGGTATTTCTCGTGGTAGCGCC
GCGGCGGTTATTGCTAGTTCATTAGCGGTAAGTTTTACGCCAACAGGGGTGGATGCAATACGTGCAAGTGAAGCTTTAGG
TATGGACTTGATGAGTTATGTTTCTCATTATCAAGCTCCAACATCGGTAGCAACTATGGTGGTTATCGGTATTATGCATG
TTATTTGGCAGACACAGGTTGATAAAAAGCATCCTGAACAATTCGAACAAGCATCAATTGAACAGACACAAAAAGAGGAA
GTGTTAGCACCTAGTTATTATGTCATTTTACCTTTGCTTCCTATTATTATGGCTGTTGTGTTTTCTAAACTCGTCATTTC
AACGATCAATATGGATGTGACGACGATTGTATTTGTTTCAATGTTTGTTGCTATGTTGTGTGAATGCATAACGAAAAGAA
GTTTAAAAACGGTTTTTGATGGTTTCAATGTGTTCTCAAAAGGAATGGGGAGTGCATTTAGCAGTGTGGTTGTATTATTA
GTTGCTGCTGGTGTTTTTGCTTATGGAATTCAAGCGACAGGAGCGATTACCAACCTAATCATGATGGCTAAATCAGTGGG
CTTACCAAGTGTAGCGATGACATTTGTTTTTGCTGTTGTGACGTTAATGGCTGCGGTGATTATGGGGTCGGGGAATGCGC
CATTCTTGGCGTTTGTTGAATTAATTCCTACTATAGCTTCCAGTATGGGAGCCAACGCAGCGGCAATGCTAATGCCAATG
CAACAAGCCTCAGCAATAGGTCGAGCAATGTCTCCTGTTTCTGCTGTTGTTATTGCTTCAGCAACGGGTGCCAAGTTAAG
TCCATTTGAAGTTGCAAAGCGAACATCTGTTCCAGTCTTAGTAGGCTTTGTGTTTCATTTTGTTATTGTTTACGCTTTTT
ATAGCTAA

Upstream 100 bases:

>100_bases
ACTCTATATTTGAATACCTTCCTGTCCCATCTTTAATTGCTGCAAGTAATGTTGTGAAAACAATCATTATTAACTTAACG
AAACATGAAGAGGTGTAGTC

Downstream 100 bases:

>100_bases
ATAGTTAATCAAATAAATACTATCATAATAAAAAGCCACACTACCTAAAATTCCCAAAATAGGTATGTGTGGCTTTATTA
GTTTATTAGATTAACGGATG

Product: anaerobic C4-dicarboxylate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MASLLLVLIVVVIAARMILKGYKAEPTLLMSGTILIFATGLFGWGPMLPASVTSTNFSGFEPFKYIQFLMGYRAGALGLM
IMALVGFADYMSHIGANDVVVRLATKPLSRIQNKNIMLFFAYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGISRGSA
AAVIASSLAVSFTPTGVDAIRASEALGMDLMSYVSHYQAPTSVATMVVIGIMHVIWQTQVDKKHPEQFEQASIEQTQKEE
VLAPSYYVILPLLPIIMAVVFSKLVISTINMDVTTIVFVSMFVAMLCECITKRSLKTVFDGFNVFSKGMGSAFSSVVVLL
VAAGVFAYGIQATGAITNLIMMAKSVGLPSVAMTFVFAVVTLMAAVIMGSGNAPFLAFVELIPTIASSMGANAAAMLMPM
QQASAIGRAMSPVSAVVIASATGAKLSPFEVAKRTSVPVLVGFVFHFVIVYAFYS

Sequences:

>Translated_455_residues
MASLLLVLIVVVIAARMILKGYKAEPTLLMSGTILIFATGLFGWGPMLPASVTSTNFSGFEPFKYIQFLMGYRAGALGLM
IMALVGFADYMSHIGANDVVVRLATKPLSRIQNKNIMLFFAYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGISRGSA
AAVIASSLAVSFTPTGVDAIRASEALGMDLMSYVSHYQAPTSVATMVVIGIMHVIWQTQVDKKHPEQFEQASIEQTQKEE
VLAPSYYVILPLLPIIMAVVFSKLVISTINMDVTTIVFVSMFVAMLCECITKRSLKTVFDGFNVFSKGMGSAFSSVVVLL
VAAGVFAYGIQATGAITNLIMMAKSVGLPSVAMTFVFAVVTLMAAVIMGSGNAPFLAFVELIPTIASSMGANAAAMLMPM
QQASAIGRAMSPVSAVVIASATGAKLSPFEVAKRTSVPVLVGFVFHFVIVYAFYS
>Mature_454_residues
ASLLLVLIVVVIAARMILKGYKAEPTLLMSGTILIFATGLFGWGPMLPASVTSTNFSGFEPFKYIQFLMGYRAGALGLMI
MALVGFADYMSHIGANDVVVRLATKPLSRIQNKNIMLFFAYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGISRGSAA
AVIASSLAVSFTPTGVDAIRASEALGMDLMSYVSHYQAPTSVATMVVIGIMHVIWQTQVDKKHPEQFEQASIEQTQKEEV
LAPSYYVILPLLPIIMAVVFSKLVISTINMDVTTIVFVSMFVAMLCECITKRSLKTVFDGFNVFSKGMGSAFSSVVVLLV
AAGVFAYGIQATGAITNLIMMAKSVGLPSVAMTFVFAVVTLMAAVIMGSGNAPFLAFVELIPTIASSMGANAAAMLMPMQ
QASAIGRAMSPVSAVVIASATGAKLSPFEVAKRTSVPVLVGFVFHFVIVYAFYS

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=426, Percent_Identity=45.0704225352113, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1789622, Length=452, Percent_Identity=34.9557522123894, Blast_Score=263, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 48238; Mature: 48106

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLLLVLIVVVIAARMILKGYKAEPTLLMSGTILIFATGLFGWGPMLPASVTSTNFSGF
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EPFKYIQFLMGYRAGALGLMIMALVGFADYMSHIGANDVVVRLATKPLSRIQNKNIMLFF
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHCCCCCEEEH
AYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGISRGSAAAVIASSLAVSFTPTGVDAI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCHHHH
RASEALGMDLMSYVSHYQAPTSVATMVVIGIMHVIWQTQVDKKHPEQFEQASIEQTQKEE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VLAPSYYVILPLLPIIMAVVFSKLVISTINMDVTTIVFVSMFVAMLCECITKRSLKTVFD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFNVFSKGMGSAFSSVVVLLVAAGVFAYGIQATGAITNLIMMAKSVGLPSVAMTFVFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLMAAVIMGSGNAPFLAFVELIPTIASSMGANAAAMLMPMQQASAIGRAMSPVSAVVIAS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHEEE
ATGAKLSPFEVAKRTSVPVLVGFVFHFVIVYAFYS
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASLLLVLIVVVIAARMILKGYKAEPTLLMSGTILIFATGLFGWGPMLPASVTSTNFSGF
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
EPFKYIQFLMGYRAGALGLMIMALVGFADYMSHIGANDVVVRLATKPLSRIQNKNIMLFF
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHCCCCCEEEH
AYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGISRGSAAAVIASSLAVSFTPTGVDAI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCHHHH
RASEALGMDLMSYVSHYQAPTSVATMVVIGIMHVIWQTQVDKKHPEQFEQASIEQTQKEE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VLAPSYYVILPLLPIIMAVVFSKLVISTINMDVTTIVFVSMFVAMLCECITKRSLKTVFD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFNVFSKGMGSAFSSVVVLLVAAGVFAYGIQATGAITNLIMMAKSVGLPSVAMTFVFAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TLMAAVIMGSGNAPFLAFVELIPTIASSMGANAAAMLMPMQQASAIGRAMSPVSAVVIAS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHEEE
ATGAKLSPFEVAKRTSVPVLVGFVFHFVIVYAFYS
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]