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The map label for this gene is ygeV [H]

Identifier: 59711605

GI number: 59711605

Start: 1100277

End: 1101845

Strand: Reverse

Name: ygeV [H]

Synonym: VF_0998

Alternate gene names: 59711605

Gene position: 1101845-1100277 (Counterclockwise)

Preceding gene: 59711606

Following gene: 172087683

Centisome position: 38.03

GC content: 36.52

Gene sequence:

>1569_bases
ATGCCAGAGCTATTAATGAATATTACTTCAGAACAACAAAGTGACTTTAATAAATTCACTCAATGTTGGTTATCTGGAAT
TTTAAAACACAGTGGTGCCCAAAAGGTAATTTGCTTTTTATCGCAACCTTCTGGTGCACAGTTATTTAAAATGGCTGAAG
GTTATTCTGACTCTAAACATCAACCTCAAATCACCTCTTTGCCTTTTGAGAATAAAAACGACAAAAATAACATCATAAAT
ACCGATTATCGTGAATTTAATACGTTAACTCTCTGTATGAGTGAAGGGCGTAATTTTAATCTTCATTTTAGTCAATGTAC
TGATGATATTAAGCATATTTTATTCGAACAATCAGAGTATTACACTCTAACCGATGGTGAAGTTGAATTTATGCCATTAA
GAAATTCACAACAAAGAATTTCAGGCGTACTCATGTTTTATTTCTCCAATTTTAGTACTTACCAAAAAAGTGATCGCCAA
ACAATTTATACCCTTAACTCACTTGCTATTGACCGAATCGCACTAGCAATTAAAAACAGTTACGCTTTATTGGATCAAAA
GATTGCTCCTCATTCATCAACAACCCACATCCCATCTGATTTTAATATTGTTGGCGATAGTAGTGCGATAAAAGAGGTGC
GCCTTAATATATCTAAAGCGCTACACATTAATCGAAATGTATTGGTTACTGGTGAAACAGGAAGCGGTAAAGAACTTATC
GCAAAAGCTATTCATCAATTTGGTAATAGAAGAAACGAGCCATACGTCGTACAAAACTGTGCCTCCATTCCTGAGCACCT
ACTTGAAAGTGAGTTATTTGGTTATCAAAAAGGAGCGTTTACTGGAGCGGATAGAGATTACATTGGTTTAATCCGATCCG
CTGACAAAGGTATCCTATTTTTAGATGAAATCGGAGATATGCCAAGCTCACTTCAAGCCAAGCTGCTTCGCGTATTAGAA
GAGAAAAAAGTTCGCCCATTAGGGTCAACTACCCTTTACGATATTGATGTCAAAGTTGTTGCAGCAACACACCAAGCTTT
AATCAAAAAAATTGAGCAAGGTGAATTCCGTCAAGACCTCTATTTCCGTTTAGCACAATTTACCATCGCTCTTCCTCCAC
TTAGAGAGCGTTATGGCGACATCGCTTTATTGAGTCATTTTTTTACTAAGCATTATGCTTTAGAGCTCCATCAACCTACC
CCCGCATTAACCAATGAGTTTATCAGCTACCTTGATAATTACTCATTTCCAGGGAATGTTCGTGAGCTAAAAAACATCAT
AGAGCGTTGCTGTATGGAAGCGCCTGACTGCCAACAGTTAGATAAATCTGTCATAGAAAAAGTCTTGAATAGCATCATGA
TGATGACGCCAAAAGAGAATAAAGAACAGGCGTTAACTGGCAGCTTATCTTCTCAAATAGACCAATTTGAGAAGAACGTT
TTAATGCAATATTTAGAGAAACATCAAGGACACTTGCAGACCATAGCTAACCATTTAGAGCTATCAAAAGGTTCTCTTGA
TTATCGATTACGAAAATTTAATTTATCCGCCAAGGAATGGAGATATTAA

Upstream 100 bases:

>100_bases
AAATACTGCTAGCACTGGCTAGAAAAGAACCATTAACCAGTATTTCTTTATGTATTGATGAAAATGGCCAAGTCTTTTGC
GAGTTTGAGGACTAGCCATC

Downstream 100 bases:

>100_bases
GCATGTTGTTACGCTTTTCACTAATCACAACCCTATTACTGCTGTCAGCATGCAGCAATTACGATGAATATCGTCCTGTT
GGCAACCCTGCTCCACAAGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MPELLMNITSEQQSDFNKFTQCWLSGILKHSGAQKVICFLSQPSGAQLFKMAEGYSDSKHQPQITSLPFENKNDKNNIIN
TDYREFNTLTLCMSEGRNFNLHFSQCTDDIKHILFEQSEYYTLTDGEVEFMPLRNSQQRISGVLMFYFSNFSTYQKSDRQ
TIYTLNSLAIDRIALAIKNSYALLDQKIAPHSSTTHIPSDFNIVGDSSAIKEVRLNISKALHINRNVLVTGETGSGKELI
AKAIHQFGNRRNEPYVVQNCASIPEHLLESELFGYQKGAFTGADRDYIGLIRSADKGILFLDEIGDMPSSLQAKLLRVLE
EKKVRPLGSTTLYDIDVKVVAATHQALIKKIEQGEFRQDLYFRLAQFTIALPPLRERYGDIALLSHFFTKHYALELHQPT
PALTNEFISYLDNYSFPGNVRELKNIIERCCMEAPDCQQLDKSVIEKVLNSIMMMTPKENKEQALTGSLSSQIDQFEKNV
LMQYLEKHQGHLQTIANHLELSKGSLDYRLRKFNLSAKEWRY

Sequences:

>Translated_522_residues
MPELLMNITSEQQSDFNKFTQCWLSGILKHSGAQKVICFLSQPSGAQLFKMAEGYSDSKHQPQITSLPFENKNDKNNIIN
TDYREFNTLTLCMSEGRNFNLHFSQCTDDIKHILFEQSEYYTLTDGEVEFMPLRNSQQRISGVLMFYFSNFSTYQKSDRQ
TIYTLNSLAIDRIALAIKNSYALLDQKIAPHSSTTHIPSDFNIVGDSSAIKEVRLNISKALHINRNVLVTGETGSGKELI
AKAIHQFGNRRNEPYVVQNCASIPEHLLESELFGYQKGAFTGADRDYIGLIRSADKGILFLDEIGDMPSSLQAKLLRVLE
EKKVRPLGSTTLYDIDVKVVAATHQALIKKIEQGEFRQDLYFRLAQFTIALPPLRERYGDIALLSHFFTKHYALELHQPT
PALTNEFISYLDNYSFPGNVRELKNIIERCCMEAPDCQQLDKSVIEKVLNSIMMMTPKENKEQALTGSLSSQIDQFEKNV
LMQYLEKHQGHLQTIANHLELSKGSLDYRLRKFNLSAKEWRY
>Mature_521_residues
PELLMNITSEQQSDFNKFTQCWLSGILKHSGAQKVICFLSQPSGAQLFKMAEGYSDSKHQPQITSLPFENKNDKNNIINT
DYREFNTLTLCMSEGRNFNLHFSQCTDDIKHILFEQSEYYTLTDGEVEFMPLRNSQQRISGVLMFYFSNFSTYQKSDRQT
IYTLNSLAIDRIALAIKNSYALLDQKIAPHSSTTHIPSDFNIVGDSSAIKEVRLNISKALHINRNVLVTGETGSGKELIA
KAIHQFGNRRNEPYVVQNCASIPEHLLESELFGYQKGAFTGADRDYIGLIRSADKGILFLDEIGDMPSSLQAKLLRVLEE
KKVRPLGSTTLYDIDVKVVAATHQALIKKIEQGEFRQDLYFRLAQFTIALPPLRERYGDIALLSHFFTKHYALELHQPTP
ALTNEFISYLDNYSFPGNVRELKNIIERCCMEAPDCQQLDKSVIEKVLNSIMMMTPKENKEQALTGSLSSQIDQFEKNVL
MQYLEKHQGHLQTIANHLELSKGSLDYRLRKFNLSAKEWRY

Specific function: Unknown

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=324, Percent_Identity=37.6543209876543, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1789087, Length=273, Percent_Identity=44.6886446886447, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI87082117, Length=371, Percent_Identity=37.1967654986523, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI1788550, Length=445, Percent_Identity=32.1348314606742, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1788905, Length=268, Percent_Identity=42.910447761194, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1790437, Length=407, Percent_Identity=32.6781326781327, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI87082152, Length=313, Percent_Identity=37.3801916932907, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1790299, Length=362, Percent_Identity=34.8066298342541, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1786524, Length=328, Percent_Identity=37.8048780487805, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787583, Length=317, Percent_Identity=35.6466876971609, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=41.1255411255411, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789828, Length=263, Percent_Identity=33.4600760456274, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081858, Length=296, Percent_Identity=27.7027027027027, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR000014
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 59678; Mature: 59547

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELLMNITSEQQSDFNKFTQCWLSGILKHSGAQKVICFLSQPSGAQLFKMAEGYSDSKH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCCCCCC
QPQITSLPFENKNDKNNIINTDYREFNTLTLCMSEGRNFNLHFSQCTDDIKHILFEQSEY
CCCEECCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCE
YTLTDGEVEFMPLRNSQQRISGVLMFYFSNFSTYQKSDRQTIYTLNSLAIDRIALAIKNS
EEEECCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHCCCCEEEEHHHHHHHHHHHHHHCH
YALLDQKIAPHSSTTHIPSDFNIVGDSSAIKEVRLNISKALHINRNVLVTGETGSGKELI
HHHHHHCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHEEECCEEEEECCCCCCHHHH
AKAIHQFGNRRNEPYVVQNCASIPEHLLESELFGYQKGAFTGADRDYIGLIRSADKGILF
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEE
LDEIGDMPSSLQAKLLRVLEEKKVRPLGSTTLYDIDVKVVAATHQALIKKIEQGEFRQDL
EHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCHHHHH
YFRLAQFTIALPPLRERYGDIALLSHFFTKHYALELHQPTPALTNEFISYLDNYSFPGNV
HHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCH
RELKNIIERCCMEAPDCQQLDKSVIEKVLNSIMMMTPKENKEQALTGSLSSQIDQFEKNV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LMQYLEKHQGHLQTIANHLELSKGSLDYRLRKFNLSAKEWRY
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHCCC
>Mature Secondary Structure 
PELLMNITSEQQSDFNKFTQCWLSGILKHSGAQKVICFLSQPSGAQLFKMAEGYSDSKH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCCCCCC
QPQITSLPFENKNDKNNIINTDYREFNTLTLCMSEGRNFNLHFSQCTDDIKHILFEQSEY
CCCEECCCCCCCCCCCCCCCCCHHHHHEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCE
YTLTDGEVEFMPLRNSQQRISGVLMFYFSNFSTYQKSDRQTIYTLNSLAIDRIALAIKNS
EEEECCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHCCCCEEEEHHHHHHHHHHHHHHCH
YALLDQKIAPHSSTTHIPSDFNIVGDSSAIKEVRLNISKALHINRNVLVTGETGSGKELI
HHHHHHCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHEEECCEEEEECCCCCCHHHH
AKAIHQFGNRRNEPYVVQNCASIPEHLLESELFGYQKGAFTGADRDYIGLIRSADKGILF
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEE
LDEIGDMPSSLQAKLLRVLEEKKVRPLGSTTLYDIDVKVVAATHQALIKKIEQGEFRQDL
EHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCHHHHH
YFRLAQFTIALPPLRERYGDIALLSHFFTKHYALELHQPTPALTNEFISYLDNYSFPGNV
HHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCH
RELKNIIERCCMEAPDCQQLDKSVIEKVLNSIMMMTPKENKEQALTGSLSSQIDQFEKNV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LMQYLEKHQGHLQTIANHLELSKGSLDYRLRKFNLSAKEWRY
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]